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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for TEAD3_TEAD1
Z-value: 1.13
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Transcription factors associated with TEAD3_TEAD1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TEAD1 | hg19_v2_chr11_+_12696102_12696164 | -0.83 | 1.7e-01 | Click! |
| TEAD3 | hg19_v2_chr6_-_35464727_35464738 | 0.73 | 2.7e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_-_132272504 Show fit | 1.55 |
ENST00000367976.3
|
connective tissue growth factor |
|
| chr10_-_90712520 Show fit | 1.38 |
ENST00000224784.6
|
actin, alpha 2, smooth muscle, aorta |
|
| chr2_-_20212422 Show fit | 0.98 |
ENST00000421259.2
ENST00000407540.3 |
matrilin 3 |
|
| chr3_-_112360116 Show fit | 0.84 |
ENST00000206423.3
ENST00000439685.2 |
coiled-coil domain containing 80 |
|
| chr3_+_134032331 Show fit | 0.76 |
ENST00000482019.1
|
RP11-200A1.1 |
|
| chr3_-_127541194 Show fit | 0.70 |
ENST00000453507.2
|
monoglyceride lipase |
|
| chrX_+_106163626 Show fit | 0.64 |
ENST00000336803.1
|
claudin 2 |
|
| chr14_-_23446900 Show fit | 0.63 |
ENST00000556731.1
|
ajuba LIM protein |
|
| chr19_-_49567124 Show fit | 0.62 |
ENST00000301411.3
|
neurotrophin 4 |
|
| chr6_-_42110342 Show fit | 0.60 |
ENST00000356542.5
|
chromosome 6 open reading frame 132 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TEAD3_TEAD1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.5 | 1.5 | GO:0034059 | response to anoxia(GO:0034059) |
| 0.3 | 1.3 | GO:0090131 | mesenchyme migration(GO:0090131) |
| 0.2 | 1.0 | GO:1903412 | response to bile acid(GO:1903412) |
| 0.1 | 1.0 | GO:0060480 | lung goblet cell differentiation(GO:0060480) |
| 0.0 | 1.0 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.0 | 0.8 | GO:0061339 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.1 | 0.7 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.0 | 0.7 | GO:0070886 | positive regulation of calcineurin-NFAT signaling cascade(GO:0070886) |
| 0.0 | 0.7 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.2 | 1.4 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.0 | 0.9 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.7 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 0.1 | 0.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.0 | 0.7 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.5 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.1 | 0.4 | GO:1990851 | Wnt-Frizzled-LRP5/6 complex(GO:1990851) |
| 0.1 | 0.4 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.0 | 0.4 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.6 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.1 | 1.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.1 | 1.0 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 0.8 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 0.0 | 0.8 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.0 | 0.8 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.7 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.0 | 0.7 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 0.6 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.1 | 0.6 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 1.4 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 1.4 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 1.3 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 1.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.7 | PID SHP2 PATHWAY | SHP2 signaling |
| 0.0 | 0.7 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.0 | 0.6 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.0 | 0.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.5 | PID IL27 PATHWAY | IL27-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 1.6 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.0 | 1.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 1.1 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 1.0 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.0 | 0.8 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.0 | 0.6 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.5 | REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES | Genes involved in p75NTR recruits signalling complexes |
| 0.0 | 0.5 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.5 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |