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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for TAF1
Z-value: 3.44
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Transcription factors associated with TAF1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TAF1 | hg19_v2_chrX_+_70586082_70586114 | 0.96 | 4.1e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of TAF1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.1 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.2 | 6.3 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.4 | 5.5 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.1 | 4.1 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.4 | 4.0 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.0 | 3.8 | GO:0070936 | protein K48-linked ubiquitination(GO:0070936) |
| 0.4 | 3.7 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.3 | 3.5 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.8 | 3.1 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 0.2 | 3.0 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.5 | GO:0000798 | nuclear cohesin complex(GO:0000798) |
| 0.3 | 5.5 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
| 0.0 | 4.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 4.9 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.2 | 4.5 | GO:0097227 | sperm annulus(GO:0097227) |
| 0.3 | 4.0 | GO:0000796 | condensin complex(GO:0000796) |
| 0.0 | 3.7 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 3.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 3.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.4 | 2.9 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.7 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 5.3 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.0 | 5.0 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 4.9 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 4.6 | GO:0019213 | deacetylase activity(GO:0019213) |
| 0.0 | 3.7 | GO:0019003 | GDP binding(GO:0019003) |
| 0.0 | 3.5 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.1 | 3.3 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.1 | 3.3 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 2.9 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.1 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 7.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 6.0 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 5.7 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 4.2 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 3.1 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 2.9 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.1 | 2.8 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.0 | 2.8 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.1 | 2.6 | ST G ALPHA S PATHWAY | G alpha s Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 10.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 5.0 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 4.7 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |
| 0.1 | 4.5 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 4.2 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 3.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 3.1 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 2.7 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 2.5 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 2.4 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |