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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for STAT6
Z-value: 0.63
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Transcription factors associated with STAT6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| STAT6 | hg19_v2_chr12_-_57504069_57504123 | -0.91 | 9.2e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_-_3469181 Show fit | 0.78 |
ENST00000366116.2
|
Uncharacterized protein |
|
| chr5_+_667759 Show fit | 0.63 |
ENST00000594226.1
|
Uncharacterized protein |
|
| chr1_-_179834311 Show fit | 0.51 |
ENST00000553856.1
|
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA. |
|
| chr7_-_50628745 Show fit | 0.48 |
ENST00000380984.4
ENST00000357936.5 ENST00000426377.1 |
dopa decarboxylase (aromatic L-amino acid decarboxylase) |
|
| chr3_+_172034218 Show fit | 0.47 |
ENST00000366261.2
|
Uncharacterized protein |
|
| chr15_+_96869165 Show fit | 0.44 |
ENST00000421109.2
|
nuclear receptor subfamily 2, group F, member 2 |
|
| chr1_-_36020531 Show fit | 0.41 |
ENST00000440579.1
ENST00000494948.1 |
KIAA0319-like |
|
| chr4_-_120988229 Show fit | 0.38 |
ENST00000296509.6
|
MAD2 mitotic arrest deficient-like 1 (yeast) |
|
| chr1_+_45965725 Show fit | 0.38 |
ENST00000401061.4
|
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
|
| chr7_+_106415457 Show fit | 0.36 |
ENST00000490162.2
ENST00000470135.1 |
RP5-884M6.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of STAT6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 0.5 | GO:0015842 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) isoquinoline alkaloid metabolic process(GO:0033076) |
| 0.1 | 0.4 | GO:0009956 | radial pattern formation(GO:0009956) |
| 0.1 | 0.4 | GO:0009236 | cobalamin biosynthetic process(GO:0009236) |
| 0.0 | 0.4 | GO:0090267 | positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267) |
| 0.1 | 0.3 | GO:1903565 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.1 | 0.3 | GO:0002874 | regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925) |
| 0.1 | 0.3 | GO:0042144 | vacuole fusion, non-autophagic(GO:0042144) |
| 0.1 | 0.3 | GO:0015742 | alpha-ketoglutarate transport(GO:0015742) |
| 0.1 | 0.3 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.0 | 0.3 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 0.0 | 0.3 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.0 | 0.2 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.0 | 0.2 | GO:0030891 | VCB complex(GO:0030891) |
| 0.0 | 0.2 | GO:0000798 | nuclear cohesin complex(GO:0000798) |
| 0.0 | 0.2 | GO:0032039 | integrator complex(GO:0032039) |
| 0.0 | 0.2 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 0.1 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.0 | 0.1 | GO:0045298 | tubulin complex(GO:0045298) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.4 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.1 | 0.3 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.1 | 0.3 | GO:0047223 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223) |
| 0.0 | 0.2 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 0.2 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 0.2 | GO:0005025 | transforming growth factor beta receptor activity, type I(GO:0005025) |
| 0.0 | 0.2 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.0 | 0.2 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.0 | 0.1 | GO:0002094 | polyprenyltransferase activity(GO:0002094) |
| 0.0 | 0.1 | GO:0004917 | interleukin-7 receptor activity(GO:0004917) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 0.4 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.0 | 0.2 | REACTOME OPSINS | Genes involved in Opsins |