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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SPIC

Z-value: 1.02

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Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
SPIC
ENSG00000166211.6 Spi-C transcription factor

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_49431073 0.85 ENST00000335783.3
CENPQ
centromere protein Q
chr8_-_101733794 0.77 ENST00000523555.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr6_-_49430886 0.74 ENST00000274813.3
MUT
methylmalonyl CoA mutase
chr3_+_52321827 0.70 ENST00000473032.1
ENST00000305690.8
ENST00000354773.4
ENST00000471180.1
ENST00000436784.2
GLYCTK
glycerate kinase
chr22_-_37880543 0.66 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_138721850 0.60 ENST00000329366.4
ENST00000280097.3
HNMT
histamine N-methyltransferase
chr1_+_241695424 0.60 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chrX_+_24073048 0.57 ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr7_-_102252589 0.53 ENST00000520042.1
RASA4
RAS p21 protein activator 4
chr20_-_52687059 0.49 ENST00000371435.2
ENST00000395961.3
BCAS1
breast carcinoma amplified sequence 1
chr18_-_61089611 0.49 ENST00000591519.1
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr1_+_76251912 0.46 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr1_+_196788887 0.45 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
CFHR1
CFHR2
complement factor H-related 1
complement factor H-related 2
chr5_+_82373379 0.44 ENST00000396027.4
ENST00000511817.1
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr1_-_211848899 0.43 ENST00000366998.3
ENST00000540251.1
ENST00000366999.4
NEK2
NIMA-related kinase 2
chr5_+_82373317 0.43 ENST00000282268.3
ENST00000338635.6
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr14_-_23284703 0.42 ENST00000555911.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr3_+_16926441 0.39 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr6_+_26087646 0.38 ENST00000309234.6
HFE
hemochromatosis
chr5_+_162864575 0.37 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr7_-_91509972 0.35 ENST00000425936.1
MTERF
mitochondrial transcription termination factor
chr10_+_104614008 0.34 ENST00000369883.3
C10orf32
chromosome 10 open reading frame 32
chrX_-_51239425 0.34 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr12_-_71533055 0.34 ENST00000552128.1
TSPAN8
tetraspanin 8
chr17_-_7082861 0.34 ENST00000269299.3
ASGR1
asialoglycoprotein receptor 1
chr7_-_108209897 0.33 ENST00000313516.5
THAP5
THAP domain containing 5
chr14_+_32414059 0.33 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chr1_-_242162375 0.33 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr2_+_109065634 0.33 ENST00000409821.1
GCC2
GRIP and coiled-coil domain containing 2
chr14_-_23285069 0.32 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_+_196912902 0.32 ENST00000476712.2
ENST00000367415.5
CFHR2
complement factor H-related 2
chr11_-_64851496 0.31 ENST00000404147.3
ENST00000275517.3
CDCA5
cell division cycle associated 5
chr15_+_63682335 0.31 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1
RP11-321G12.1
chrX_-_11129229 0.30 ENST00000608176.1
ENST00000433747.2
ENST00000608576.1
ENST00000608916.1
RP11-120D5.1
RP11-120D5.1
chr5_-_60458179 0.30 ENST00000507416.1
ENST00000339020.3
SMIM15
small integral membrane protein 15
chr3_+_130613226 0.30 ENST00000509662.1
ENST00000328560.8
ENST00000428331.2
ENST00000359644.3
ENST00000422190.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr6_+_139349817 0.29 ENST00000367660.3
ABRACL
ABRA C-terminal like
chr8_-_95229531 0.29 ENST00000450165.2
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr3_+_130612803 0.29 ENST00000510168.1
ENST00000508532.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr8_+_104426942 0.29 ENST00000297579.5
DCAF13
DDB1 and CUL4 associated factor 13
chrX_+_24072833 0.29 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr14_-_23285011 0.29 ENST00000397532.3
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr5_-_93447333 0.28 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
FAM172A
family with sequence similarity 172, member A
chr12_-_44152551 0.28 ENST00000416848.2
ENST00000550784.1
ENST00000547156.1
ENST00000549868.1
ENST00000553166.1
ENST00000551923.1
ENST00000431332.3
ENST00000344862.5
PUS7L
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr15_+_75335604 0.28 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr3_-_154042205 0.28 ENST00000329463.5
DHX36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr12_-_49523896 0.27 ENST00000549870.1
TUBA1B
tubulin, alpha 1b
chr3_+_130613001 0.27 ENST00000504948.1
ENST00000513801.1
ENST00000505072.1
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr1_+_206138884 0.27 ENST00000341209.5
ENST00000607379.1
FAM72A
family with sequence similarity 72, member A
chr1_+_179335101 0.27 ENST00000508285.1
ENST00000511889.1
AXDND1
axonemal dynein light chain domain containing 1
chr1_-_197036364 0.27 ENST00000367412.1
F13B
coagulation factor XIII, B polypeptide
chr4_+_41992489 0.26 ENST00000264451.7
SLC30A9
solute carrier family 30 (zinc transporter), member 9
chr4_-_88312301 0.26 ENST00000507286.1
HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chr7_+_108210012 0.26 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr7_-_23145288 0.26 ENST00000419813.1
KLHL7-AS1
KLHL7 antisense RNA 1 (head to head)
chr5_+_158690089 0.26 ENST00000296786.6
UBLCP1
ubiquitin-like domain containing CTD phosphatase 1
chr1_-_165738072 0.26 ENST00000481278.1
TMCO1
transmembrane and coiled-coil domains 1
chr15_-_90233866 0.26 ENST00000561257.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr2_+_32853093 0.26 ENST00000448773.1
ENST00000317907.4
TTC27
tetratricopeptide repeat domain 27
chr5_-_142782862 0.25 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_-_27149904 0.25 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
ABI1
abl-interactor 1
chr2_-_152382500 0.25 ENST00000434685.1
NEB
nebulin
chr2_-_32236002 0.25 ENST00000404530.1
MEMO1
mediator of cell motility 1
chr2_+_32390925 0.24 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr19_+_32896646 0.24 ENST00000392250.2
DPY19L3
dpy-19-like 3 (C. elegans)
chr2_-_37458749 0.24 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chrX_-_100604184 0.24 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr6_-_8435706 0.24 ENST00000379660.4
SLC35B3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr21_+_17566643 0.23 ENST00000419952.1
ENST00000445461.2
LINC00478
long intergenic non-protein coding RNA 478
chr6_-_100016678 0.23 ENST00000523799.1
ENST00000520429.1
CCNC
cyclin C
chr7_-_21985489 0.23 ENST00000356195.5
ENST00000447180.1
ENST00000373934.4
ENST00000457951.1
CDCA7L
cell division cycle associated 7-like
chr1_-_143913143 0.23 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr10_-_27149851 0.23 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
ABI1
abl-interactor 1
chr10_+_91461337 0.23 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
KIF20B
kinesin family member 20B
chr3_+_101292939 0.22 ENST00000265260.3
ENST00000469941.1
ENST00000296024.5
PCNP
PEST proteolytic signal containing nuclear protein
chr11_-_22647350 0.22 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr17_+_28443819 0.22 ENST00000479218.2
NSRP1
nuclear speckle splicing regulatory protein 1
chr3_-_154042235 0.22 ENST00000308361.6
ENST00000496811.1
ENST00000544526.1
DHX36
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr19_+_36346734 0.22 ENST00000586102.3
KIRREL2
kin of IRRE like 2 (Drosophila)
chr12_+_10658489 0.22 ENST00000538173.1
EIF2S3L
Putative eukaryotic translation initiation factor 2 subunit 3-like protein
chr5_-_114632307 0.22 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr5_-_142783175 0.22 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_+_148847371 0.22 ENST00000296051.2
ENST00000460120.1
HPS3
Hermansky-Pudlak syndrome 3
chrX_-_107018969 0.22 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr10_+_115439630 0.22 ENST00000369318.3
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr1_+_150245177 0.22 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr19_+_32896697 0.22 ENST00000586987.1
DPY19L3
dpy-19-like 3 (C. elegans)
chr3_+_99979828 0.22 ENST00000485687.1
ENST00000344949.5
ENST00000394144.4
TBC1D23
TBC1 domain family, member 23
chr9_-_26947220 0.22 ENST00000520884.1
PLAA
phospholipase A2-activating protein
chr1_+_206138457 0.22 ENST00000367128.3
ENST00000431655.2
FAM72A
family with sequence similarity 72, member A
chr1_+_104068562 0.22 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr1_+_222886694 0.21 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr8_+_97657531 0.21 ENST00000519900.1
ENST00000517742.1
CPQ
carboxypeptidase Q
chr3_+_151986709 0.21 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr2_+_113299990 0.21 ENST00000537335.1
ENST00000417433.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr5_-_43313269 0.21 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr15_-_33360085 0.21 ENST00000334528.9
FMN1
formin 1
chr9_-_95640218 0.21 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484
zinc finger protein 484
chr9_-_140095186 0.21 ENST00000409012.4
TPRN
taperin
chrX_-_135056106 0.21 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chr10_+_104613980 0.21 ENST00000339834.5
C10orf32
chromosome 10 open reading frame 32
chr19_-_9731872 0.21 ENST00000424629.1
ENST00000326044.5
ENST00000354661.4
ENST00000435550.1
ENST00000444611.1
ENST00000421525.1
ZNF561
zinc finger protein 561
chr6_-_91296602 0.21 ENST00000369325.3
ENST00000369327.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr2_-_26101314 0.20 ENST00000336112.4
ENST00000272341.4
ASXL2
additional sex combs like 2 (Drosophila)
chr1_-_54519134 0.20 ENST00000371341.1
TMEM59
transmembrane protein 59
chr14_-_39639523 0.20 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
TRAPPC6B
trafficking protein particle complex 6B
chr8_-_104427289 0.20 ENST00000543107.1
SLC25A32
solute carrier family 25 (mitochondrial folate carrier), member 32
chr5_-_148929848 0.20 ENST00000504676.1
ENST00000515435.1
CSNK1A1
casein kinase 1, alpha 1
chr10_-_18944123 0.20 ENST00000606425.1
RP11-139J15.7
Uncharacterized protein
chr6_-_151773232 0.20 ENST00000444024.1
ENST00000367303.4
RMND1
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr6_-_100016527 0.20 ENST00000523985.1
ENST00000518714.1
ENST00000520371.1
CCNC
cyclin C
chr8_-_27941380 0.20 ENST00000413272.2
ENST00000341513.6
NUGGC
nuclear GTPase, germinal center associated
chr10_+_115439699 0.20 ENST00000369315.1
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr3_+_179322481 0.20 ENST00000259037.3
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr2_+_233925064 0.20 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr3_+_149530836 0.19 ENST00000466478.1
ENST00000491086.1
ENST00000467977.1
RNF13
ring finger protein 13
chr22_-_36013368 0.19 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr10_+_115439282 0.19 ENST00000369321.2
ENST00000345633.4
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr19_-_6481776 0.19 ENST00000543576.1
ENST00000590173.1
ENST00000381480.2
DENND1C
DENN/MADD domain containing 1C
chr11_+_22646739 0.19 ENST00000428556.2
AC103801.2
AC103801.2
chr17_+_21730180 0.19 ENST00000584398.1
UBBP4
ubiquitin B pseudogene 4
chr1_+_233463507 0.19 ENST00000366623.3
ENST00000366624.3
MLK4
Mitogen-activated protein kinase kinase kinase MLK4
chr5_+_102455968 0.19 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr9_-_135282195 0.19 ENST00000334270.2
TTF1
transcription termination factor, RNA polymerase I
chr15_-_90456156 0.19 ENST00000357484.5
C15orf38
chromosome 15 open reading frame 38
chr3_-_176914238 0.19 ENST00000430069.1
ENST00000428970.1
TBL1XR1
transducin (beta)-like 1 X-linked receptor 1
chr4_-_159094194 0.19 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr17_+_37844331 0.19 ENST00000578199.1
ENST00000406381.2
ERBB2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr9_-_95087838 0.18 ENST00000442668.2
ENST00000421075.2
ENST00000536624.1
NOL8
nucleolar protein 8
chr17_+_62075703 0.18 ENST00000577953.1
ENST00000582540.1
ENST00000579184.1
ENST00000425164.3
ENST00000412177.1
ENST00000539996.1
ENST00000583891.1
ENST00000580752.1
C17orf72
chromosome 17 open reading frame 72
chr17_+_18684563 0.18 ENST00000476139.1
TVP23B
trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
chr5_+_115177178 0.18 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr7_-_108210048 0.18 ENST00000415914.3
ENST00000438865.1
THAP5
THAP domain containing 5
chr6_+_3849584 0.18 ENST00000380274.1
ENST00000380272.3
FAM50B
family with sequence similarity 50, member B
chr16_-_15736881 0.18 ENST00000540441.2
KIAA0430
KIAA0430
chr8_+_86019382 0.18 ENST00000360375.3
LRRCC1
leucine rich repeat and coiled-coil centrosomal protein 1
chr1_+_150245099 0.18 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr19_-_50464338 0.18 ENST00000426971.2
ENST00000447370.2
SIGLEC11
sialic acid binding Ig-like lectin 11
chr7_+_99613195 0.18 ENST00000324306.6
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr6_-_91296737 0.18 ENST00000369332.3
ENST00000369329.3
MAP3K7
mitogen-activated protein kinase kinase kinase 7
chr12_-_120884175 0.18 ENST00000546954.1
TRIAP1
TP53 regulated inhibitor of apoptosis 1
chr6_+_151773583 0.17 ENST00000545879.1
C6orf211
chromosome 6 open reading frame 211
chr3_-_121379739 0.17 ENST00000428394.2
ENST00000314583.3
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_194030493 0.17 ENST00000456816.1
ENST00000414120.1
ENST00000429578.1
LINC00887
long intergenic non-protein coding RNA 887
chr19_-_42758040 0.17 ENST00000593944.1
ERF
Ets2 repressor factor
chr11_+_72983246 0.17 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr16_+_57576584 0.17 ENST00000340339.4
GPR114
G protein-coupled receptor 114
chr2_+_67624430 0.17 ENST00000272342.5
ETAA1
Ewing tumor-associated antigen 1
chrY_+_15016725 0.17 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_+_158519654 0.17 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chrX_-_48858630 0.17 ENST00000376425.3
ENST00000376444.3
GRIPAP1
GRIP1 associated protein 1
chr12_+_19593515 0.17 ENST00000360995.4
AEBP2
AE binding protein 2
chrX_+_55478538 0.17 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr10_+_94590910 0.17 ENST00000371547.4
EXOC6
exocyst complex component 6
chr4_-_110723134 0.17 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr14_-_57735528 0.17 ENST00000340918.7
ENST00000413566.2
EXOC5
exocyst complex component 5
chr3_+_179322573 0.17 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr4_-_89152474 0.17 ENST00000515655.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr18_+_6256746 0.16 ENST00000578427.1
RP11-760N9.1
RP11-760N9.1
chr11_+_327171 0.16 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr4_-_76861392 0.16 ENST00000505594.1
NAAA
N-acylethanolamine acid amidase
chr19_-_51920952 0.16 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr4_-_155471528 0.16 ENST00000302078.5
ENST00000499023.2
PLRG1
pleiotropic regulator 1
chr2_+_64751433 0.16 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
AFTPH
aftiphilin
chr10_+_44101850 0.16 ENST00000361807.3
ENST00000374437.2
ENST00000430885.1
ENST00000374435.3
ZNF485
zinc finger protein 485
chr1_-_145470383 0.16 ENST00000369314.1
ENST00000369313.3
POLR3GL
polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like
chr3_+_156544057 0.16 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
LEKR1
leucine, glutamate and lysine rich 1
chr15_+_50716576 0.16 ENST00000560297.1
ENST00000307179.4
ENST00000396444.3
ENST00000433963.1
ENST00000425032.3
USP8
ubiquitin specific peptidase 8
chr19_-_52307357 0.16 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr22_-_38539185 0.16 ENST00000452542.1
PLA2G6
phospholipase A2, group VI (cytosolic, calcium-independent)
chr15_-_90234006 0.16 ENST00000300056.3
ENST00000559170.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr10_+_51576285 0.16 ENST00000443446.1
NCOA4
nuclear receptor coactivator 4
chr9_-_26947453 0.16 ENST00000397292.3
PLAA
phospholipase A2-activating protein
chr5_-_130970723 0.16 ENST00000308008.6
ENST00000296859.6
ENST00000507093.1
ENST00000510071.1
ENST00000509018.1
ENST00000307984.5
RAPGEF6
Rap guanine nucleotide exchange factor (GEF) 6
chr2_-_201374781 0.16 ENST00000359878.3
ENST00000409157.1
KCTD18
potassium channel tetramerization domain containing 18
chr8_-_74205851 0.16 ENST00000396467.1
RPL7
ribosomal protein L7
chr17_+_28443799 0.16 ENST00000584423.1
ENST00000247026.5
NSRP1
nuclear speckle splicing regulatory protein 1
chr19_-_2090131 0.16 ENST00000591326.1
MOB3A
MOB kinase activator 3A
chr8_-_101962777 0.15 ENST00000395951.3
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr14_-_23292596 0.15 ENST00000554741.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chrX_-_48858667 0.15 ENST00000376423.4
ENST00000376441.1
GRIPAP1
GRIP1 associated protein 1
chr2_-_64751227 0.15 ENST00000561559.1
RP11-568N6.1
RP11-568N6.1
chr3_+_101659682 0.15 ENST00000465215.1
RP11-221J22.1
RP11-221J22.1
chr5_+_175299743 0.15 ENST00000502265.1
CPLX2
complexin 2
chr2_-_26101374 0.15 ENST00000435504.4
ASXL2
additional sex combs like 2 (Drosophila)
chr1_-_71546690 0.15 ENST00000254821.6
ZRANB2
zinc finger, RAN-binding domain containing 2
chr2_+_27805880 0.15 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512
zinc finger protein 512
chr7_+_74188309 0.15 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr1_-_108742957 0.15 ENST00000565488.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr2_-_40006289 0.15 ENST00000260619.6
ENST00000454352.2
THUMPD2
THUMP domain containing 2
chr15_-_75917955 0.15 ENST00000568162.1
ENST00000563875.1
SNUPN
snurportin 1
chr1_+_246729815 0.15 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr5_-_10249990 0.15 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B
family with sequence similarity 173, member B
chr17_-_60005365 0.15 ENST00000444766.3
INTS2
integrator complex subunit 2
chr1_-_220445757 0.15 ENST00000358951.2
RAB3GAP2
RAB3 GTPase activating protein subunit 2 (non-catalytic)
chr2_+_201981527 0.15 ENST00000441224.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr5_-_74062867 0.15 ENST00000509097.1
GFM2
G elongation factor, mitochondrial 2
chr1_+_110091189 0.15 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr10_+_37414785 0.15 ENST00000374660.1
ENST00000602533.1
ENST00000361713.1
ANKRD30A
ankyrin repeat domain 30A
chrX_+_27826107 0.15 ENST00000356790.2
MAGEB10
melanoma antigen family B, 10

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0001692 histamine metabolic process(GO:0001692)
0.2 1.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.6 GO:1903542 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.1 0.4 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.1 0.4 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.7 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 1.0 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
0.1 0.3 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 0.8 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.1 0.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.3 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.4 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 0.6 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.5 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.1 0.4 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 0.5 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.7 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.1 0.3 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.3 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 0.9 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.3 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.1 GO:1903371 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.6 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.3 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.5 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.6 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.0 GO:1903378 positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.0 0.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.1 GO:0034059 response to anoxia(GO:0034059)
0.0 0.1 GO:0010585 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.1 GO:0070374 positive regulation of ERK1 and ERK2 cascade(GO:0070374)
0.0 0.1 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.0 0.1 GO:0070206 protein trimerization(GO:0070206)
0.0 0.0 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.0 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.2 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.4 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0006045 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.9 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.6 GO:0043101 purine-containing compound salvage(GO:0043101)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.0 0.5 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.0 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.0 0.1 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0060585 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.1 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.2 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.2 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.1 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410) positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.2 GO:0071372 response to vitamin E(GO:0033197) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:0060174 limb bud formation(GO:0060174)
0.0 0.1 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.0 GO:0090135 actin filament branching(GO:0090135)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:1903943 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.0 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.0 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.0 0.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 1.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.3 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.5 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.3 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.6 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 1.4 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.1 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.1 0.3 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 0.4 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.1 0.3 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.2 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.6 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.5 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.2 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 0.6 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.5 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 1.0 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.3 GO:0052846 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.8 GO:0008494 translation activator activity(GO:0008494)
0.0 0.2 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.5 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.1 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.1 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.2 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0045118 azole transporter activity(GO:0045118)
0.0 0.3 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.0 0.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.4 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0015065 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0032089 NACHT domain binding(GO:0032089)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0005346 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.6 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.1 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.2 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A