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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SPDEF

Z-value: 1.02

Motif logo

Transcription factors associated with SPDEF

Gene Symbol Gene ID Gene Info
ENSG00000124664.6 SAM pointed domain containing ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SPDEFhg19_v2_chr6_-_34524049_345240910.455.5e-01Click!

Activity profile of SPDEF motif

Sorted Z-values of SPDEF motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_105212297 0.88 ENST00000556623.1
ENST00000555674.1
adenylosuccinate synthase like 1
chr7_-_91875109 0.81 ENST00000412043.2
ENST00000430102.1
ENST00000425073.1
ENST00000394503.2
ENST00000454017.1
ENST00000440209.1
ENST00000413688.1
ENST00000452773.1
ENST00000433016.1
ENST00000394505.2
ENST00000422347.1
ENST00000458493.1
ENST00000425919.1
KRIT1, ankyrin repeat containing
chr12_+_102513950 0.80 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARP1 binding protein
chr5_+_158690089 0.66 ENST00000296786.6
ubiquitin-like domain containing CTD phosphatase 1
chr19_+_38880695 0.65 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chr1_-_65533390 0.57 ENST00000448344.1
RP4-535B20.1
chr5_+_110074685 0.53 ENST00000355943.3
ENST00000447245.2
solute carrier family 25, member 46
chr1_+_193028717 0.53 ENST00000415442.2
ENST00000506303.1
TROVE domain family, member 2
chr6_+_134274322 0.53 ENST00000367871.1
ENST00000237264.4
TBP-like 1
chr4_+_48833312 0.50 ENST00000508293.1
ENST00000513391.2
OCIA domain containing 1
chr4_+_48833183 0.47 ENST00000503016.1
OCIA domain containing 1
chr2_+_27805880 0.44 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
zinc finger protein 512
chr1_-_184723942 0.44 ENST00000318130.8
ER degradation enhancer, mannosidase alpha-like 3
chr10_-_119806085 0.43 ENST00000355624.3
RAB11 family interacting protein 2 (class I)
chrX_-_131352152 0.43 ENST00000342983.2
RAP2C, member of RAS oncogene family
chr15_-_64648273 0.43 ENST00000607537.1
ENST00000303052.7
ENST00000303032.6
casein kinase 1, gamma 1
chr7_+_99613195 0.42 ENST00000324306.6
zinc finger with KRAB and SCAN domains 1
chr17_-_7108436 0.42 ENST00000493294.1
discs, large homolog 4 (Drosophila)
chr4_+_41992489 0.41 ENST00000264451.7
solute carrier family 30 (zinc transporter), member 9
chr1_-_193028426 0.40 ENST00000367450.3
ENST00000530098.2
ENST00000367451.4
ENST00000367448.1
ENST00000367449.1
ubiquitin carboxyl-terminal hydrolase L5
chr15_-_55700457 0.39 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
cell cycle progression 1
chr2_+_37311588 0.39 ENST00000409774.1
ENST00000608836.1
G patch domain containing 11
chr7_+_77428066 0.39 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
putative homeodomain transcription factor 2
chr7_-_38948774 0.38 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr1_+_67395922 0.37 ENST00000401042.3
ENST00000355356.3
mesoderm induction early response 1, transcriptional regulator
chr4_+_153701081 0.37 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ADP-ribosylation factor interacting protein 1
chr1_+_235492300 0.36 ENST00000476121.1
ENST00000497327.1
geranylgeranyl diphosphate synthase 1
chr8_+_100025476 0.35 ENST00000355155.1
ENST00000357162.2
ENST00000358544.2
ENST00000395996.1
ENST00000441350.2
vacuolar protein sorting 13 homolog B (yeast)
chr2_+_47596634 0.35 ENST00000419334.1
epithelial cell adhesion molecule
chr14_-_64010006 0.34 ENST00000555899.1
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr1_-_193028632 0.34 ENST00000421683.1
ubiquitin carboxyl-terminal hydrolase L5
chr2_-_128785619 0.34 ENST00000450957.1
Sin3A-associated protein, 130kDa
chr16_+_77224732 0.33 ENST00000569610.1
ENST00000248248.3
ENST00000567291.1
ENST00000320859.6
ENST00000563612.1
ENST00000563279.1
MON1 secretory trafficking family member B
chr7_-_91875358 0.33 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1, ankyrin repeat containing
chr3_-_37218023 0.31 ENST00000416425.1
leucine rich repeat (in FLII) interacting protein 2
chr17_-_33905521 0.31 ENST00000225873.4
peroxisomal biogenesis factor 12
chr16_-_25122785 0.30 ENST00000563962.1
ENST00000569920.1
RP11-449H11.1
chr11_+_65383227 0.30 ENST00000355703.3
pecanex-like 3 (Drosophila)
chr1_+_235491714 0.29 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
geranylgeranyl diphosphate synthase 1
chr1_-_169337176 0.29 ENST00000472647.1
ENST00000367811.3
NME/NM23 family member 7
chr15_-_65809991 0.29 ENST00000559526.1
ENST00000358939.4
ENST00000560665.1
ENST00000321118.7
ENST00000339244.5
ENST00000300141.6
dipeptidyl-peptidase 8
chr4_-_44728559 0.28 ENST00000509756.1
ENST00000507917.1
ENST00000295448.3
glucosamine-6-phosphate deaminase 2
chr4_+_48833015 0.28 ENST00000509122.1
ENST00000509664.1
ENST00000505922.2
ENST00000514981.1
OCIA domain containing 1
chr1_+_84630053 0.28 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
protein kinase, cAMP-dependent, catalytic, beta
chr8_-_77912431 0.28 ENST00000357039.4
ENST00000522527.1
peroxisomal biogenesis factor 2
chr5_+_31532373 0.28 ENST00000325366.9
ENST00000355907.3
ENST00000507818.2
chromosome 5 open reading frame 22
chr9_-_72374848 0.27 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
protein prenyltransferase alpha subunit repeat containing 1
chr14_+_89029866 0.27 ENST00000557693.1
ENST00000555120.1
zinc finger CCCH-type containing 14
chr5_+_86564739 0.27 ENST00000456692.2
ENST00000512763.1
ENST00000506290.1
RAS p21 protein activator (GTPase activating protein) 1
chrX_-_135962876 0.27 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr14_-_64010046 0.26 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr12_+_102514019 0.26 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARP1 binding protein
chr1_+_193028552 0.25 ENST00000400968.2
ENST00000432079.1
TROVE domain family, member 2
chr15_-_55700216 0.25 ENST00000569205.1
cell cycle progression 1
chr19_-_52674896 0.25 ENST00000322146.8
ENST00000597065.1
zinc finger protein 836
chr18_+_21033239 0.25 ENST00000581585.1
ENST00000577501.1
RIO kinase 3
chr7_+_77428149 0.25 ENST00000415251.2
ENST00000275575.7
putative homeodomain transcription factor 2
chr3_+_32023232 0.24 ENST00000360311.4
zinc finger protein 860
chr6_+_30524663 0.24 ENST00000376560.3
proline rich 3
chrX_-_154299501 0.24 ENST00000369476.3
ENST00000369484.3
mature T-cell proliferation 1
C-x(9)-C motif containing 4
chr15_-_55700522 0.24 ENST00000564092.1
ENST00000310958.6
cell cycle progression 1
chr8_-_101964265 0.24 ENST00000395958.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr2_+_65454926 0.23 ENST00000542850.1
ENST00000377982.4
ARP2 actin-related protein 2 homolog (yeast)
chr2_-_63815628 0.23 ENST00000409562.3
WD repeat containing planar cell polarity effector
chr6_+_30525051 0.23 ENST00000376557.3
proline rich 3
chr2_+_54014168 0.23 ENST00000405123.3
ENST00000185150.4
ENST00000378239.5
endoplasmic reticulum lectin 1
chr14_+_89029323 0.23 ENST00000554602.1
zinc finger CCCH-type containing 14
chr2_+_187350973 0.23 ENST00000544130.1
zinc finger CCCH-type containing 15
chr17_+_65714018 0.23 ENST00000581106.1
ENST00000535137.1
nucleolar protein 11
chr11_-_61197406 0.23 ENST00000541963.1
ENST00000477890.2
cleavage and polyadenylation specific factor 7, 59kDa
chr22_-_41215328 0.23 ENST00000434185.1
ENST00000435456.2
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr4_+_141445311 0.22 ENST00000323570.3
ENST00000511887.2
ELMO/CED-12 domain containing 2
chr4_+_48833234 0.21 ENST00000510824.1
ENST00000425583.2
OCIA domain containing 1
chr1_+_44435646 0.21 ENST00000255108.3
ENST00000412950.2
ENST00000396758.2
DPH2 homolog (S. cerevisiae)
chr14_+_89029336 0.21 ENST00000556945.1
ENST00000556158.1
ENST00000557607.1
zinc finger CCCH-type containing 14
chr2_+_39103103 0.20 ENST00000340556.6
ENST00000410014.1
ENST00000409665.1
ENST00000409077.2
ENST00000409131.2
MORN repeat containing 2
chr13_+_111855414 0.20 ENST00000375737.5
Rho guanine nucleotide exchange factor (GEF) 7
chr5_+_76326187 0.20 ENST00000312916.7
ENST00000506806.1
angiogenic factor with G patch and FHA domains 1
chr14_+_60716159 0.20 ENST00000325658.3
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr10_-_14996321 0.20 ENST00000378289.4
DNA cross-link repair 1C
chr7_-_135662056 0.20 ENST00000393085.3
ENST00000435723.1
myotrophin
chr1_+_151129103 0.19 ENST00000368910.3
tumor necrosis factor, alpha-induced protein 8-like 2
chr10_-_15902449 0.19 ENST00000277632.3
family with sequence similarity 188, member A
chr14_-_21567009 0.19 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
zinc finger protein 219
chr1_+_213224572 0.19 ENST00000543470.1
ENST00000366960.3
ENST00000366959.3
ENST00000543354.1
ribosomal protein S6 kinase, 52kDa, polypeptide 1
chr12_-_64616019 0.19 ENST00000311915.8
ENST00000398055.3
ENST00000544871.1
chromosome 12 open reading frame 66
chr14_+_89029366 0.19 ENST00000555799.1
ENST00000555755.1
ENST00000393514.5
zinc finger CCCH-type containing 14
chr16_+_25123148 0.19 ENST00000570981.1
leucine carboxyl methyltransferase 1
chr18_-_55288973 0.18 ENST00000423481.2
ENST00000587194.1
ENST00000591599.1
ENST00000588661.1
asparaginyl-tRNA synthetase
chr22_-_22337154 0.18 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
topoisomerase (DNA) III beta
chr4_+_48833070 0.18 ENST00000511662.1
ENST00000508996.1
ENST00000507210.1
ENST00000264312.7
ENST00000396448.2
ENST00000512236.1
ENST00000509164.1
ENST00000511102.1
ENST00000381473.3
OCIA domain containing 1
chrX_+_117629766 0.18 ENST00000276204.6
ENST00000276202.7
dedicator of cytokinesis 11
chr2_+_118846008 0.18 ENST00000245787.4
insulin induced gene 2
chr10_+_5726764 0.18 ENST00000328090.5
ENST00000496681.1
family with sequence similarity 208, member B
chr1_+_203765437 0.18 ENST00000550078.1
zinc finger, BED-type containing 6
chr2_+_187350883 0.18 ENST00000337859.6
zinc finger CCCH-type containing 15
chr14_-_74416829 0.17 ENST00000534936.1
family with sequence similarity 161, member B
chr17_-_47755436 0.17 ENST00000505581.1
ENST00000514121.1
ENST00000393328.2
ENST00000509079.1
ENST00000393331.3
ENST00000347630.2
ENST00000504102.1
speckle-type POZ protein
chr3_-_133380731 0.17 ENST00000260810.5
topoisomerase (DNA) II binding protein 1
chr14_-_69263043 0.17 ENST00000408913.2
ZFP36 ring finger protein-like 1
chr4_-_83812248 0.17 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31 homolog A (S. cerevisiae)
chr5_+_892745 0.17 ENST00000166345.3
thyroid hormone receptor interactor 13
chr2_+_198380289 0.17 ENST00000233892.4
ENST00000409916.1
MOB family member 4, phocein
chr2_+_27805971 0.17 ENST00000413371.2
zinc finger protein 512
chr6_-_143832793 0.17 ENST00000438118.2
fucosidase, alpha-L- 2, plasma
chr1_-_193028621 0.17 ENST00000367455.4
ENST00000367454.1
ubiquitin carboxyl-terminal hydrolase L5
chrX_-_122866874 0.17 ENST00000245838.8
ENST00000355725.4
THO complex 2
chr13_+_46039037 0.17 ENST00000349995.5
component of oligomeric golgi complex 3
chr4_-_83812402 0.17 ENST00000395310.2
SEC31 homolog A (S. cerevisiae)
chr12_+_69080734 0.17 ENST00000378905.2
nucleoporin 107kDa
chr2_+_37311645 0.16 ENST00000281932.5
G patch domain containing 11
chr4_+_48833160 0.16 ENST00000506801.1
OCIA domain containing 1
chr17_+_65713925 0.16 ENST00000253247.4
nucleolar protein 11
chr14_-_24711764 0.16 ENST00000557921.1
ENST00000558476.1
TERF1 (TRF1)-interacting nuclear factor 2
chr2_+_162016916 0.15 ENST00000405852.1
TRAF family member-associated NFKB activator
chr12_+_22199108 0.15 ENST00000229329.2
cytidine monophosphate N-acetylneuraminic acid synthetase
chr8_-_130951940 0.15 ENST00000522250.1
ENST00000522941.1
ENST00000522746.1
ENST00000520204.1
ENST00000519070.1
ENST00000520254.1
ENST00000519824.2
ENST00000519540.1
family with sequence similarity 49, member B
chr12_+_109490370 0.15 ENST00000257548.5
ENST00000536723.1
ENST00000536393.1
ubiquitin specific peptidase 30
chrX_+_69509870 0.15 ENST00000374388.3
kinesin family member 4A
chr2_+_148602058 0.15 ENST00000241416.7
ENST00000535787.1
ENST00000404590.1
activin A receptor, type IIA
chr11_+_61129827 0.15 ENST00000542946.1
transmembrane protein 138
chr17_-_56065484 0.15 ENST00000581208.1
vascular endothelial zinc finger 1
chr15_-_65809581 0.15 ENST00000341861.5
dipeptidyl-peptidase 8
chr11_+_36616355 0.15 ENST00000532470.2
chromosome 11 open reading frame 74
chr14_+_24701870 0.15 ENST00000561035.1
ENST00000559409.1
ENST00000558865.1
ENST00000558279.1
guanosine monophosphate reductase 2
chr2_+_162165038 0.15 ENST00000437630.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr2_+_138721850 0.15 ENST00000329366.4
ENST00000280097.3
histamine N-methyltransferase
chr22_-_41215291 0.14 ENST00000542412.1
ENST00000544408.1
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr11_-_46722117 0.14 ENST00000311956.4
Rho GTPase activating protein 1
chr15_+_80987617 0.14 ENST00000258884.4
ENST00000558464.1
abhydrolase domain containing 17C
chr14_+_89029253 0.14 ENST00000251038.5
ENST00000359301.3
ENST00000302216.8
zinc finger CCCH-type containing 14
chr9_+_34458851 0.14 ENST00000545019.1
dynein, axonemal, intermediate chain 1
chr18_-_19180681 0.14 ENST00000269214.5
establishment of sister chromatid cohesion N-acetyltransferase 1
chr17_+_37844331 0.14 ENST00000578199.1
ENST00000406381.2
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
chr20_-_42839378 0.14 ENST00000255174.2
oxidative stress responsive serine-rich 1
chr1_+_43637996 0.13 ENST00000528956.1
ENST00000529956.1
WD repeat domain 65
chr16_+_77225071 0.13 ENST00000439557.2
ENST00000545553.1
MON1 secretory trafficking family member B
chr10_-_14996017 0.13 ENST00000378241.1
ENST00000456122.1
ENST00000418843.1
ENST00000378249.1
ENST00000396817.2
ENST00000378255.1
ENST00000378254.1
ENST00000378278.2
ENST00000357717.2
DNA cross-link repair 1C
chr2_+_66662249 0.13 ENST00000560281.2
Meis homeobox 1
chr6_-_143832820 0.13 ENST00000002165.6
fucosidase, alpha-L- 2, plasma
chr11_-_32816156 0.13 ENST00000531481.1
ENST00000335185.5
coiled-coil domain containing 73
chr2_+_162016827 0.13 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TRAF family member-associated NFKB activator
chr7_-_77427676 0.12 ENST00000257663.3
transmembrane protein 60
chr14_-_31926623 0.12 ENST00000356180.4
D-tyrosyl-tRNA deacylase 2 (putative)
chr1_-_235324530 0.12 ENST00000447801.1
ENST00000366606.3
ENST00000429912.1
RNA binding motif protein 34
chr18_+_48556470 0.12 ENST00000589076.1
ENST00000590061.1
ENST00000591914.1
ENST00000342988.3
SMAD family member 4
chr4_+_144106063 0.12 ENST00000510377.1
ubiquitin specific peptidase 38
chr15_-_65810042 0.12 ENST00000321147.6
dipeptidyl-peptidase 8
chr2_+_198380763 0.12 ENST00000448447.2
ENST00000409360.1
MOB family member 4, phocein
chr10_-_120840309 0.12 ENST00000369144.3
eukaryotic translation initiation factor 3, subunit A
chr12_+_29302119 0.12 ENST00000536681.3
fatty acyl CoA reductase 2
chr10_-_14996070 0.12 ENST00000378258.1
ENST00000453695.2
ENST00000378246.2
DNA cross-link repair 1C
chr1_+_84629976 0.12 ENST00000446538.1
ENST00000370684.1
ENST00000436133.1
protein kinase, cAMP-dependent, catalytic, beta
chr19_-_45004556 0.12 ENST00000587047.1
ENST00000391956.4
ENST00000221327.4
ENST00000586637.1
ENST00000591064.1
ENST00000592529.1
zinc finger protein 180
chr11_-_71823715 0.11 ENST00000545944.1
ENST00000502597.2
anaphase promoting complex subunit 15
chr1_-_28415075 0.11 ENST00000373863.3
ENST00000436342.2
ENST00000540618.1
ENST00000545175.1
eyes absent homolog 3 (Drosophila)
chr12_-_57914275 0.11 ENST00000547303.1
ENST00000552740.1
ENST00000547526.1
ENST00000551116.1
ENST00000346473.3
DNA-damage-inducible transcript 3
chr3_-_139108463 0.11 ENST00000512242.1
coatomer protein complex, subunit beta 2 (beta prime)
chr12_+_10366223 0.11 ENST00000545290.1
GABA(A) receptor-associated protein like 1
chr3_+_33840050 0.11 ENST00000457054.2
ENST00000413073.1
programmed cell death 6 interacting protein
chr4_+_141445333 0.11 ENST00000507667.1
ELMO/CED-12 domain containing 2
chr11_+_57480046 0.11 ENST00000378312.4
ENST00000278422.4
thioredoxin-related transmembrane protein 2
chr5_-_31532238 0.11 ENST00000507438.1
drosha, ribonuclease type III
chr1_-_111506562 0.11 ENST00000485275.2
ENST00000369763.4
ligand dependent nuclear receptor interacting factor 1
chr14_+_21566980 0.11 ENST00000418511.2
ENST00000554329.2
transmembrane protein 253
chr14_-_69262947 0.11 ENST00000557086.1
ZFP36 ring finger protein-like 1
chr2_+_219536749 0.10 ENST00000295709.3
ENST00000392106.2
ENST00000392105.3
ENST00000455724.1
serine/threonine kinase 36
chr3_-_196669248 0.10 ENST00000447325.1
nuclear cap binding protein subunit 2, 20kDa
chr12_+_57914481 0.10 ENST00000548887.1
methyl-CpG binding domain protein 6
chr1_+_110091189 0.10 ENST00000369851.4
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chrX_-_152486108 0.10 ENST00000356661.5
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr8_-_100025238 0.10 ENST00000521696.1
RP11-410L14.2
chr12_+_50794592 0.10 ENST00000293618.8
ENST00000429001.3
ENST00000548174.1
ENST00000548697.1
ENST00000548993.1
ENST00000398473.2
ENST00000522085.1
ENST00000518444.1
ENST00000551886.1
La ribonucleoprotein domain family, member 4
chr3_-_37217756 0.10 ENST00000440230.1
ENST00000421276.2
ENST00000421307.1
ENST00000354379.4
leucine rich repeat (in FLII) interacting protein 2
chr12_-_120663792 0.09 ENST00000546532.1
ENST00000548912.1
paxillin
chr7_+_99613212 0.09 ENST00000426572.1
ENST00000535170.1
zinc finger with KRAB and SCAN domains 1
chr11_+_94706973 0.09 ENST00000536741.1
lysine (K)-specific demethylase 4D
chr8_-_101965146 0.09 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr8_+_8860314 0.09 ENST00000250263.7
ENST00000519292.1
exoribonuclease 1
chr3_+_100428316 0.09 ENST00000479672.1
ENST00000476228.1
ENST00000463568.1
TRK-fused gene
chr1_+_24829384 0.09 ENST00000374395.4
ENST00000436717.2
RCAN family member 3
chr8_-_56987061 0.09 ENST00000009589.3
ENST00000524349.1
ENST00000519606.1
ENST00000519807.1
ENST00000521262.1
ENST00000520627.1
ribosomal protein S20
chr6_+_134274354 0.09 ENST00000367869.1
TBP-like 1
chr18_+_11851383 0.09 ENST00000526991.2
charged multivesicular body protein 1B
chr5_+_93954039 0.09 ENST00000265140.5
ankyrin repeat domain 32
chr1_+_43124087 0.08 ENST00000304979.3
ENST00000372550.1
ENST00000440068.1
peptidylprolyl isomerase H (cyclophilin H)
chr1_-_235324772 0.08 ENST00000408888.3
RNA binding motif protein 34
chr17_-_27277615 0.08 ENST00000583747.1
ENST00000584236.1
PHD finger protein 12
chr2_+_219537015 0.08 ENST00000440309.1
ENST00000424080.1
serine/threonine kinase 36
chr19_+_37178482 0.08 ENST00000536254.2
zinc finger protein 567
chr17_-_74733404 0.08 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
serine/arginine-rich splicing factor 2
chr11_-_118122996 0.08 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
myelin protein zero-like 3
chr3_-_69101461 0.08 ENST00000543976.1
TATA element modulatory factor 1
chr14_+_60715928 0.08 ENST00000395076.4
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_169337172 0.08 ENST00000367807.3
ENST00000367808.3
ENST00000329281.2
ENST00000420531.1
basic leucine zipper nuclear factor 1
chr3_+_57541975 0.08 ENST00000487257.1
ENST00000311180.8
phosphodiesterase 12
chr14_-_69262916 0.08 ENST00000553375.1
ZFP36 ring finger protein-like 1
chr4_+_144106080 0.07 ENST00000307017.4
ubiquitin specific peptidase 38
chr20_+_42839600 0.07 ENST00000439943.1
ENST00000437730.1
OSER1 antisense RNA 1 (head to head)
chr3_+_38495333 0.07 ENST00000352511.4
activin A receptor, type IIB

Network of associatons between targets according to the STRING database.

First level regulatory network of SPDEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.2 0.9 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.2 0.5 GO:0019085 early viral transcription(GO:0019085)
0.1 0.9 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.1 0.4 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.1 0.4 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.3 GO:0006043 glucosamine catabolic process(GO:0006043)
0.1 0.6 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 1.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.1 0.4 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.3 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.3 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1 0.2 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.4 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0 0.2 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 1.0 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.9 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.4 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688) regulation of grooming behavior(GO:2000821)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.3 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.3 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.5 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0 1.1 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.4 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.2 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.6 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.3 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.3 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.4 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.0 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.1 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.6 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 1.1 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.5 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.4 GO:0044447 axoneme part(GO:0044447)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.7 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.4 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.4 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.3 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.2 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.6 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.3 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.1 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.3 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 1.0 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.3 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.1 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.5 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0031013 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) troponin I binding(GO:0031013)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL