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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SOX7

Z-value: 1.01

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Transcription factors associated with SOX7

Gene Symbol Gene ID Gene Info
ENSG00000171056.6 SRY-box transcription factor 7
ENSG00000258724.1 SRY-box transcription factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX7hg19_v2_chr8_-_10588010_10588030-0.722.8e-01Click!

Activity profile of SOX7 motif

Sorted Z-values of SOX7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_190445499 1.31 ENST00000261024.2
solute carrier family 40 (iron-regulated transporter), member 1
chr12_-_57443886 1.07 ENST00000300119.3
myosin IA
chr2_-_152118276 0.88 ENST00000409092.1
RNA binding motif protein 43
chr21_+_34144411 0.86 ENST00000382375.4
ENST00000453404.1
ENST00000382378.1
ENST00000477513.1
chromosome 21 open reading frame 49
chr1_+_100598691 0.73 ENST00000370143.1
ENST00000370141.2
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr12_-_90049878 0.72 ENST00000359142.3
ATPase, Ca++ transporting, plasma membrane 1
chrY_+_14813160 0.69 ENST00000338981.3
ubiquitin specific peptidase 9, Y-linked
chr12_-_90049828 0.60 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr4_-_39034542 0.59 ENST00000344606.6
transmembrane protein 156
chr8_-_102803163 0.56 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
neurocalcin delta
chr12_+_64173583 0.50 ENST00000261234.6
transmembrane protein 5
chr10_-_71169031 0.50 ENST00000373307.1
tachykinin receptor 2
chr19_-_21950332 0.48 ENST00000598026.1
zinc finger protein 100
chr12_-_39734783 0.45 ENST00000552961.1
kinesin family member 21A
chr19_-_5784610 0.43 ENST00000390672.2
ENST00000419421.2
proline rich 22
chr10_+_122610687 0.41 ENST00000263461.6
WD repeat domain 11
chr2_+_179317994 0.41 ENST00000375129.4
deafness, autosomal recessive 59
chr1_+_10509971 0.40 ENST00000320498.4
cortistatin
chr3_-_123411191 0.38 ENST00000354792.5
ENST00000508240.1
myosin light chain kinase
chr6_-_86303833 0.31 ENST00000505648.1
sorting nexin 14
chr10_-_12084770 0.28 ENST00000357604.5
UPF2 regulator of nonsense transcripts homolog (yeast)
chr19_-_38916839 0.28 ENST00000433821.2
ENST00000426920.2
ENST00000587753.1
ENST00000454404.2
ENST00000293062.9
RAS guanyl releasing protein 4
chr19_+_37837185 0.27 ENST00000541583.2
HKR1, GLI-Kruppel zinc finger family member
chr15_+_63414760 0.27 ENST00000557972.1
lactamase, beta
chr10_+_5005445 0.27 ENST00000380872.4
aldo-keto reductase family 1, member C1
chr6_+_29555683 0.26 ENST00000383640.2
olfactory receptor, family 2, subfamily H, member 2
chr14_+_60712463 0.25 ENST00000325642.3
ENST00000529574.1
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr3_+_107318157 0.25 ENST00000406780.1
bobby sox homolog (Drosophila)
chr11_-_62474803 0.24 ENST00000533982.1
ENST00000360796.5
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr10_-_5652705 0.23 ENST00000425246.1
RP11-336A10.5
chr16_-_28303360 0.21 ENST00000501520.1
RP11-57A19.2
chr19_+_37837218 0.20 ENST00000591134.1
HKR1, GLI-Kruppel zinc finger family member
chr15_+_66585950 0.20 ENST00000525109.1
DIS3 mitotic control homolog (S. cerevisiae)-like
chr17_-_65235916 0.19 ENST00000579861.1
helicase with zinc finger
chr6_-_111804905 0.18 ENST00000358835.3
ENST00000435970.1
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chr12_-_57328187 0.18 ENST00000293502.1
short chain dehydrogenase/reductase family 9C, member 7
chr12_-_58027138 0.18 ENST00000341156.4
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr14_-_31856397 0.18 ENST00000538864.2
ENST00000550366.1
HEAT repeat containing 5A
chr18_+_32820990 0.18 ENST00000601719.1
ENST00000591206.1
ENST00000330501.7
ENST00000261333.6
ENST00000355632.4
ENST00000585800.1
zinc finger protein 397
chr1_-_54303934 0.18 ENST00000537333.1
NDC1 transmembrane nucleoporin
chr19_-_38916822 0.16 ENST00000586305.1
RAS guanyl releasing protein 4
chr1_+_100598742 0.14 ENST00000370139.1
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr17_-_28661065 0.14 ENST00000328886.4
ENST00000538566.2
transmembrane and immunoglobulin domain containing 1
chr5_-_95158644 0.14 ENST00000237858.6
glutaredoxin (thioltransferase)
chr17_+_80858418 0.13 ENST00000574422.1
tubulin folding cofactor D
chr13_-_28024681 0.13 ENST00000381116.1
ENST00000381120.3
ENST00000431572.2
mitochondrial translational initiation factor 3
chr5_-_95158375 0.13 ENST00000512469.2
ENST00000379979.4
ENST00000505427.1
ENST00000508780.1
glutaredoxin (thioltransferase)
chr1_+_40810516 0.12 ENST00000435168.2
small ArfGAP2
chr6_+_168434678 0.10 ENST00000496008.1
kinesin family member 25
chr1_-_43751230 0.09 ENST00000523677.1
chromosome 1 open reading frame 210
chr1_+_156698708 0.08 ENST00000519086.1
ribosomal RNA adenine dimethylase domain containing 1
chr6_+_147527103 0.07 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr10_-_17243579 0.07 ENST00000525762.1
ENST00000412821.3
ENST00000351358.4
ENST00000377766.5
ENST00000358282.7
ENST00000488990.1
ENST00000377799.3
tRNA aspartic acid methyltransferase 1
chr17_-_39623681 0.07 ENST00000225899.3
keratin 32
chr6_+_150690133 0.06 ENST00000392255.3
ENST00000500320.3
iodotyrosine deiodinase
chr10_+_96162242 0.06 ENST00000225235.4
TBC1 domain family, member 12
chr10_-_96829246 0.06 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
cytochrome P450, family 2, subfamily C, polypeptide 8
chr6_+_144164455 0.05 ENST00000367576.5
LTV1 homolog (S. cerevisiae)
chrX_+_69353284 0.05 ENST00000342206.6
ENST00000356413.4
immunoglobulin (CD79A) binding protein 1
chr12_-_123728548 0.05 ENST00000545406.1
M-phase phosphoprotein 9
chr6_+_80129989 0.04 ENST00000429444.1
RP1-232L24.3
chr9_-_37592561 0.03 ENST00000544379.1
ENST00000377773.5
ENST00000401811.3
ENST00000321301.6
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr9_-_70465758 0.02 ENST00000489273.1
COBW domain containing 5
chr1_+_158901329 0.01 ENST00000368140.1
ENST00000368138.3
ENST00000392254.2
ENST00000392252.3
ENST00000368135.4
pyrin and HIN domain family, member 1
chr16_+_28303804 0.00 ENST00000341901.4
SH3 domain binding kinase 1
chr6_-_3195981 0.00 ENST00000425384.2
ENST00000435043.2
RP1-40E16.9

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.1 1.3 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.5 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.1 0.2 GO:0070632 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 1.1 GO:0030033 microvillus assembly(GO:0030033)
0.0 0.1 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.4 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.8 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.2 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 0.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 1.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004995 tachykinin receptor activity(GO:0004995)
0.1 1.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.3 GO:0047023 androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 1.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.8 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors