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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SOX6

Z-value: 0.69

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Transcription factors associated with SOX6

Gene Symbol Gene ID Gene Info
SOX6
ENSG00000110693.11 SRY-box transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX6hg19_v2_chr11_-_16430399_164304400.881.2e-01Click!

Activity profile of SOX6 motif

Sorted Z-values of SOX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_50628745 0.66 ENST00000380984.4
ENST00000357936.5
ENST00000426377.1
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr3_-_148939598 0.61 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr4_+_89300158 0.54 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr6_+_64282447 0.48 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_-_108278456 0.46 ENST00000429168.1
SEC63
SEC63 homolog (S. cerevisiae)
chr10_-_25241499 0.41 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr12_-_58145889 0.41 ENST00000547853.1
CDK4
cyclin-dependent kinase 4
chr11_-_76155618 0.39 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr2_-_157198860 0.39 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chrX_-_106959631 0.39 ENST00000486554.1
ENST00000372390.4
TSC22D3
TSC22 domain family, member 3
chr8_-_124741451 0.37 ENST00000520519.1
ANXA13
annexin A13
chr11_-_62414070 0.36 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chr3_+_181429704 0.32 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr3_-_167813672 0.32 ENST00000470487.1
GOLIM4
golgi integral membrane protein 4
chr12_-_49581152 0.31 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr14_+_50234827 0.31 ENST00000554589.1
ENST00000557247.1
KLHDC2
kelch domain containing 2
chr4_-_105416039 0.31 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr1_-_26233423 0.31 ENST00000357865.2
STMN1
stathmin 1
chr13_+_110958124 0.30 ENST00000400163.2
COL4A2
collagen, type IV, alpha 2
chr3_-_8686479 0.30 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr16_-_15736881 0.30 ENST00000540441.2
KIAA0430
KIAA0430
chr1_-_93645818 0.29 ENST00000370280.1
ENST00000479918.1
TMED5
transmembrane emp24 protein transport domain containing 5
chr20_-_52645231 0.29 ENST00000448484.1
BCAS1
breast carcinoma amplified sequence 1
chr1_-_65533390 0.29 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr12_-_89919220 0.28 ENST00000549035.1
ENST00000393179.4
POC1B
POC1 centriolar protein B
chr22_-_39052300 0.27 ENST00000355830.6
FAM227A
family with sequence similarity 227, member A
chr14_+_74815116 0.26 ENST00000256362.4
VRTN
vertebrae development associated
chr15_+_52311398 0.26 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr14_-_51027838 0.26 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_228337553 0.26 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr4_-_140477928 0.26 ENST00000274031.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr20_+_61448376 0.26 ENST00000343916.3
COL9A3
collagen, type IX, alpha 3
chr9_-_123476719 0.26 ENST00000373930.3
MEGF9
multiple EGF-like-domains 9
chr9_-_88896977 0.26 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chr22_-_42336209 0.26 ENST00000472374.2
CENPM
centromere protein M
chr16_-_3068171 0.25 ENST00000572154.1
ENST00000328796.4
CLDN6
claudin 6
chr6_-_29527702 0.25 ENST00000377050.4
UBD
ubiquitin D
chr4_+_95128996 0.25 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_-_26232951 0.25 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr1_-_26232522 0.25 ENST00000399728.1
STMN1
stathmin 1
chr16_-_30798492 0.25 ENST00000262525.4
ZNF629
zinc finger protein 629
chr20_-_1317555 0.25 ENST00000537552.1
AL136531.1
HCG2043693; Uncharacterized protein
chr12_+_11081828 0.24 ENST00000381847.3
ENST00000396400.3
PRH2
proline-rich protein HaeIII subfamily 2
chr6_-_135375921 0.24 ENST00000367820.2
ENST00000314674.3
ENST00000524715.1
ENST00000415177.2
ENST00000367826.2
HBS1L
HBS1-like (S. cerevisiae)
chr12_+_50479101 0.24 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr4_+_95129061 0.24 ENST00000354268.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_+_95128748 0.24 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr20_+_48884002 0.23 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr8_+_107738240 0.23 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr12_-_88974236 0.23 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr3_-_148939835 0.23 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr2_+_70056762 0.23 ENST00000282570.3
GMCL1
germ cell-less, spermatogenesis associated 1
chr8_+_27631903 0.22 ENST00000305188.8
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chrX_-_63425561 0.22 ENST00000374869.3
ENST00000330258.3
AMER1
APC membrane recruitment protein 1
chr20_-_17511962 0.21 ENST00000377873.3
BFSP1
beaded filament structural protein 1, filensin
chr1_+_150229554 0.21 ENST00000369111.4
CA14
carbonic anhydrase XIV
chr10_+_35416223 0.21 ENST00000489321.1
ENST00000427847.2
ENST00000345491.3
ENST00000395895.2
ENST00000374728.3
ENST00000487132.1
CREM
cAMP responsive element modulator
chr4_+_2819883 0.21 ENST00000511747.1
ENST00000503393.2
SH3BP2
SH3-domain binding protein 2
chr17_+_72667239 0.21 ENST00000402449.4
RAB37
RAB37, member RAS oncogene family
chrX_+_80457442 0.20 ENST00000373212.5
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr3_+_112930306 0.20 ENST00000495514.1
BOC
BOC cell adhesion associated, oncogene regulated
chr3_-_123339343 0.20 ENST00000578202.1
MYLK
myosin light chain kinase
chr17_+_21729899 0.20 ENST00000583708.1
UBBP4
ubiquitin B pseudogene 4
chr1_+_47799542 0.20 ENST00000471289.2
ENST00000450808.2
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr17_+_21729593 0.19 ENST00000581769.1
ENST00000584755.1
UBBP4
ubiquitin B pseudogene 4
chr6_+_122720681 0.19 ENST00000368455.4
ENST00000452194.1
HSF2
heat shock transcription factor 2
chr1_-_204436344 0.19 ENST00000367184.2
PIK3C2B
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr11_-_102323489 0.19 ENST00000361236.3
TMEM123
transmembrane protein 123
chr1_+_68150744 0.19 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr12_+_104359614 0.19 ENST00000266775.9
ENST00000544861.1
TDG
thymine-DNA glycosylase
chr12_+_95611536 0.19 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr12_+_8849773 0.19 ENST00000541044.1
RIMKLB
ribosomal modification protein rimK-like family member B
chr17_+_21730180 0.19 ENST00000584398.1
UBBP4
ubiquitin B pseudogene 4
chr2_-_86790593 0.18 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr15_-_54025300 0.18 ENST00000559418.1
WDR72
WD repeat domain 72
chr5_-_173043591 0.18 ENST00000285908.5
ENST00000480951.1
ENST00000311086.4
BOD1
biorientation of chromosomes in cell division 1
chr12_-_105478339 0.18 ENST00000424857.2
ENST00000258494.9
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr1_+_166808667 0.18 ENST00000537173.1
ENST00000536514.1
ENST00000449930.1
POGK
pogo transposable element with KRAB domain
chr11_-_8892464 0.18 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
ST5
suppression of tumorigenicity 5
chr2_-_55276320 0.18 ENST00000357376.3
RTN4
reticulon 4
chr1_+_14075865 0.18 ENST00000413440.1
PRDM2
PR domain containing 2, with ZNF domain
chr13_-_41593425 0.18 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_-_167813132 0.18 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr7_+_139528952 0.17 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr1_-_26324534 0.17 ENST00000374284.1
ENST00000441420.1
ENST00000374282.3
PAFAH2
platelet-activating factor acetylhydrolase 2, 40kDa
chr12_+_104359576 0.17 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr2_-_175202151 0.17 ENST00000595354.1
AC018470.1
Uncharacterized protein FLJ46347
chr14_-_71107921 0.17 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr15_+_101402041 0.17 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
RP11-66B24.1
chr2_-_70475701 0.17 ENST00000282574.4
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr16_+_68573640 0.16 ENST00000398253.2
ENST00000573161.1
ZFP90
ZFP90 zinc finger protein
chr13_+_51913819 0.16 ENST00000419898.2
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr11_-_102323740 0.16 ENST00000398136.2
TMEM123
transmembrane protein 123
chr11_+_19799327 0.16 ENST00000540292.1
NAV2
neuron navigator 2
chr2_+_27805880 0.16 ENST00000379717.1
ENST00000355467.4
ENST00000556601.1
ENST00000416005.2
ZNF512
zinc finger protein 512
chr21_-_16437126 0.15 ENST00000318948.4
NRIP1
nuclear receptor interacting protein 1
chr21_-_16437255 0.15 ENST00000400199.1
ENST00000400202.1
NRIP1
nuclear receptor interacting protein 1
chr16_-_31085033 0.15 ENST00000414399.1
ZNF668
zinc finger protein 668
chr14_-_96830207 0.15 ENST00000359933.4
ATG2B
autophagy related 2B
chr3_+_151986709 0.15 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
MBNL1
muscleblind-like splicing regulator 1
chr19_+_49468558 0.15 ENST00000331825.6
FTL
ferritin, light polypeptide
chr22_-_38480100 0.15 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr17_-_53046058 0.14 ENST00000571584.1
ENST00000299335.3
COX11
cytochrome c oxidase assembly homolog 11 (yeast)
chr2_-_70475730 0.14 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1
TIA1 cytotoxic granule-associated RNA binding protein
chr7_+_73868439 0.14 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr6_-_64029879 0.14 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr17_+_27920486 0.14 ENST00000394859.3
ANKRD13B
ankyrin repeat domain 13B
chr6_+_83777374 0.14 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
DOPEY1
dopey family member 1
chr7_+_134464414 0.14 ENST00000361901.2
CALD1
caldesmon 1
chr11_+_125365110 0.14 ENST00000527818.1
AP000708.1
AP000708.1
chr2_-_37899323 0.14 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr12_+_124997766 0.14 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr11_+_125496619 0.14 ENST00000532669.1
ENST00000278916.3
CHEK1
checkpoint kinase 1
chr3_-_123339418 0.13 ENST00000583087.1
MYLK
myosin light chain kinase
chr5_+_110073853 0.13 ENST00000513807.1
ENST00000509442.2
SLC25A46
solute carrier family 25, member 46
chr21_+_35552978 0.13 ENST00000428914.2
ENST00000609062.1
ENST00000609947.1
LINC00310
long intergenic non-protein coding RNA 310
chr15_+_93426514 0.13 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2
chr15_-_56035177 0.13 ENST00000389286.4
ENST00000561292.1
PRTG
protogenin
chr9_-_39239171 0.13 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr10_+_70480963 0.13 ENST00000265872.6
ENST00000535016.1
ENST00000538031.1
ENST00000543719.1
ENST00000539539.1
ENST00000543225.1
ENST00000536012.1
ENST00000494903.2
CCAR1
cell division cycle and apoptosis regulator 1
chr17_+_36584662 0.13 ENST00000431231.2
ENST00000437668.3
ARHGAP23
Rho GTPase activating protein 23
chr3_-_15563229 0.13 ENST00000383786.5
ENST00000383787.2
ENST00000383785.2
ENST00000383788.5
ENST00000603808.1
COLQ
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr1_+_93645314 0.13 ENST00000343253.7
CCDC18
coiled-coil domain containing 18
chr2_-_47572105 0.13 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
AC073283.4
chr16_+_54964740 0.13 ENST00000394636.4
IRX5
iroquois homeobox 5
chr9_+_4662282 0.13 ENST00000381883.2
PPAPDC2
phosphatidic acid phosphatase type 2 domain containing 2
chr16_-_67970990 0.13 ENST00000358514.4
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr12_-_49582593 0.13 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr21_+_38445539 0.13 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3
tetratricopeptide repeat domain 3
chr2_+_46926326 0.12 ENST00000394861.2
SOCS5
suppressor of cytokine signaling 5
chr11_-_64013663 0.12 ENST00000392210.2
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr17_-_46716647 0.12 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr17_+_75283973 0.12 ENST00000431235.2
ENST00000449803.2
SEPT9
septin 9
chr21_+_30671690 0.12 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr5_+_134094461 0.12 ENST00000452510.2
ENST00000354283.4
DDX46
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr2_+_27070964 0.12 ENST00000288699.6
DPYSL5
dihydropyrimidinase-like 5
chr15_+_77224045 0.12 ENST00000320963.5
ENST00000394883.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr17_-_62308087 0.12 ENST00000583097.1
TEX2
testis expressed 2
chr6_+_13272904 0.12 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr1_-_6479963 0.12 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
HES2
hes family bHLH transcription factor 2
chr1_+_249200395 0.12 ENST00000355360.4
ENST00000329291.5
ENST00000539153.1
PGBD2
piggyBac transposable element derived 2
chr12_-_49582978 0.12 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr20_-_35492048 0.12 ENST00000237536.4
SOGA1
suppressor of glucose, autophagy associated 1
chr5_-_141338377 0.12 ENST00000510041.1
PCDH12
protocadherin 12
chr22_+_29168652 0.12 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr18_+_7946839 0.11 ENST00000578916.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr17_-_49124230 0.11 ENST00000510283.1
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr17_-_19648683 0.11 ENST00000573368.1
ENST00000457500.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr21_+_35553045 0.11 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr5_-_141338627 0.11 ENST00000231484.3
PCDH12
protocadherin 12
chr10_+_18429606 0.11 ENST00000324631.7
ENST00000352115.6
ENST00000377328.1
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr18_+_20494078 0.11 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
RBBP8
retinoblastoma binding protein 8
chr2_-_85641162 0.11 ENST00000447219.2
ENST00000409670.1
ENST00000409724.1
CAPG
capping protein (actin filament), gelsolin-like
chr1_+_24286287 0.11 ENST00000334351.7
ENST00000374468.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr15_+_52043758 0.11 ENST00000249700.4
ENST00000539962.2
TMOD2
tropomodulin 2 (neuronal)
chr12_-_48213735 0.11 ENST00000417902.1
ENST00000417107.1
HDAC7
histone deacetylase 7
chr17_+_52978156 0.11 ENST00000348161.4
TOM1L1
target of myb1 (chicken)-like 1
chrX_+_84498989 0.11 ENST00000395402.1
ZNF711
zinc finger protein 711
chr2_-_86564776 0.11 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1
receptor accessory protein 1
chr3_-_48470838 0.11 ENST00000358459.4
ENST00000358536.4
PLXNB1
plexin B1
chr6_-_128841503 0.10 ENST00000368215.3
ENST00000532331.1
ENST00000368213.5
ENST00000368207.3
ENST00000525459.1
ENST00000368210.3
ENST00000368226.4
ENST00000368227.3
PTPRK
protein tyrosine phosphatase, receptor type, K
chr4_+_78078304 0.10 ENST00000316355.5
ENST00000354403.5
ENST00000502280.1
CCNG2
cyclin G2
chr13_+_100153665 0.10 ENST00000376387.4
TM9SF2
transmembrane 9 superfamily member 2
chrX_+_84499038 0.10 ENST00000373165.3
ZNF711
zinc finger protein 711
chr5_+_140254884 0.10 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr1_+_166808692 0.10 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr20_+_34679725 0.10 ENST00000432589.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr12_-_53320245 0.10 ENST00000552150.1
KRT8
keratin 8
chr21_-_40720995 0.10 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chr12_+_50478977 0.10 ENST00000381513.4
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr4_-_71705027 0.10 ENST00000545193.1
GRSF1
G-rich RNA sequence binding factor 1
chr6_-_42110342 0.10 ENST00000356542.5
C6orf132
chromosome 6 open reading frame 132
chr4_-_71705060 0.10 ENST00000514161.1
GRSF1
G-rich RNA sequence binding factor 1
chr4_-_140477910 0.10 ENST00000404104.3
SETD7
SET domain containing (lysine methyltransferase) 7
chr15_-_80695917 0.10 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr17_+_75372165 0.10 ENST00000427674.2
SEPT9
septin 9
chr15_+_77223960 0.10 ENST00000394885.3
RCN2
reticulocalbin 2, EF-hand calcium binding domain
chr12_+_22778009 0.10 ENST00000266517.4
ENST00000335148.3
ETNK1
ethanolamine kinase 1
chr2_-_231989808 0.10 ENST00000258400.3
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
chr17_+_76037081 0.10 ENST00000588549.1
TNRC6C
trinucleotide repeat containing 6C
chr4_+_26585686 0.10 ENST00000505206.1
ENST00000511789.1
TBC1D19
TBC1 domain family, member 19
chr12_-_48213568 0.09 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
HDAC7
histone deacetylase 7
chr2_+_111880242 0.09 ENST00000393252.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr11_-_130184470 0.09 ENST00000357899.4
ENST00000397753.1
ZBTB44
zinc finger and BTB domain containing 44
chr15_+_52043813 0.09 ENST00000435126.2
TMOD2
tropomodulin 2 (neuronal)
chr18_+_55712915 0.09 ENST00000592846.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr9_+_71394945 0.09 ENST00000394264.3
FAM122A
family with sequence similarity 122A
chr12_+_64238539 0.09 ENST00000357825.3
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr5_-_76788024 0.09 ENST00000515253.1
ENST00000414719.2
ENST00000507654.1
ENST00000514559.1
ENST00000511791.1
WDR41
WD repeat domain 41
chr22_+_18593097 0.09 ENST00000426208.1
TUBA8
tubulin, alpha 8
chr14_-_55878538 0.09 ENST00000247178.5
ATG14
autophagy related 14
chr7_-_148725544 0.08 ENST00000413966.1
PDIA4
protein disulfide isomerase family A, member 4
chr7_+_87563557 0.08 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM22
ADAM metallopeptidase domain 22
chr2_+_42104692 0.08 ENST00000398796.2
ENST00000442214.1
AC104654.1
AC104654.1
chr9_+_139874683 0.08 ENST00000444903.1
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr17_-_19648916 0.08 ENST00000444455.1
ENST00000439102.2
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr2_-_204399976 0.08 ENST00000457812.1
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr3_-_57583052 0.08 ENST00000496292.1
ENST00000489843.1
ARF4
ADP-ribosylation factor 4
chr8_-_11660077 0.08 ENST00000533405.1
RP11-297N6.4
Uncharacterized protein
chrX_+_129473859 0.08 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) isoquinoline alkaloid metabolic process(GO:0033076)
0.2 0.5 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.1 0.4 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.4 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.4 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.2 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.4 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.3 GO:1904637 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.2 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.1 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0008037 cell recognition(GO:0008037)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.7 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0006581 acetylcholine catabolic process in synaptic cleft(GO:0001507) acetylcholine catabolic process(GO:0006581)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.7 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.1 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:1990523 bone regeneration(GO:1990523)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.3 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.3 GO:0032196 transposition(GO:0032196)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.4 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.2 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0071565 nBAF complex(GO:0071565)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.2 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.3 GO:0004803 transposase activity(GO:0004803)
0.1 0.2 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.2 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.4 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.7 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.0 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway