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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SOX30

Z-value: 1.19

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Transcription factors associated with SOX30

Gene Symbol Gene ID Gene Info
SOX30
ENSG00000039600.6 SRY-box transcription factor 30

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX30hg19_v2_chr5_-_157079372_157079395-0.604.0e-01Click!

Activity profile of SOX30 motif

Sorted Z-values of SOX30 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_100770328 1.40 ENST00000223095.4
ENST00000445463.2
SERPINE1
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr3_-_122283424 0.84 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr22_-_30970498 0.82 ENST00000431313.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr22_+_31488433 0.82 ENST00000455608.1
SMTN
smoothelin
chr5_-_146461027 0.79 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr14_+_101299520 0.64 ENST00000455531.1
MEG3
maternally expressed 3 (non-protein coding)
chr4_+_54243798 0.61 ENST00000337488.6
ENST00000358575.5
ENST00000507922.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr2_-_158182322 0.60 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr12_-_10588539 0.59 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
KLRC2
NKG2-E
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr22_-_30970560 0.59 ENST00000402369.1
ENST00000406361.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr1_+_149239529 0.55 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr17_+_67498295 0.52 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_232573208 0.52 ENST00000409115.3
PTMA
prothymosin, alpha
chr6_-_134639180 0.51 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr1_-_201476274 0.50 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr20_-_5426380 0.50 ENST00000609252.1
ENST00000422352.1
LINC00658
long intergenic non-protein coding RNA 658
chr4_-_176733897 0.49 ENST00000393658.2
GPM6A
glycoprotein M6A
chr12_+_93096619 0.49 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr14_-_36645674 0.48 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr12_+_9066472 0.47 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr12_+_93096759 0.46 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr9_-_134145880 0.46 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr11_+_46402744 0.46 ENST00000533952.1
MDK
midkine (neurite growth-promoting factor 2)
chr22_+_46449674 0.43 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr2_+_143635067 0.40 ENST00000264170.4
KYNU
kynureninase
chr4_+_54243862 0.39 ENST00000306932.6
FIP1L1
factor interacting with PAPOLA and CPSF1
chr5_+_179135246 0.38 ENST00000508787.1
CANX
calnexin
chr2_+_232573222 0.36 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr18_+_68002675 0.35 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr12_+_27623565 0.34 ENST00000535986.1
SMCO2
single-pass membrane protein with coiled-coil domains 2
chr15_+_76629064 0.34 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr6_-_161085291 0.32 ENST00000316300.5
LPA
lipoprotein, Lp(a)
chr1_+_244998602 0.31 ENST00000411948.2
COX20
COX20 cytochrome C oxidase assembly factor
chr11_-_89224638 0.30 ENST00000535633.1
ENST00000263317.4
NOX4
NADPH oxidase 4
chr1_-_21503337 0.30 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr7_+_870547 0.28 ENST00000457598.1
SUN1
Sad1 and UNC84 domain containing 1
chr12_+_95611536 0.28 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr2_+_99953816 0.28 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr3_+_19988736 0.27 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr2_+_179184955 0.27 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr1_+_244998918 0.26 ENST00000366528.3
COX20
COX20 cytochrome C oxidase assembly factor
chr10_+_35484793 0.26 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM
cAMP responsive element modulator
chr12_+_11905413 0.25 ENST00000545027.1
ETV6
ets variant 6
chr22_-_43485381 0.25 ENST00000331018.7
ENST00000266254.7
ENST00000445824.1
TTLL1
tubulin tyrosine ligase-like family, member 1
chr4_+_113152978 0.25 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr6_+_131958436 0.24 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr14_+_52456193 0.23 ENST00000261700.3
C14orf166
chromosome 14 open reading frame 166
chr6_-_49712123 0.23 ENST00000263045.4
CRISP3
cysteine-rich secretory protein 3
chr5_+_140593509 0.23 ENST00000341948.4
PCDHB13
protocadherin beta 13
chr12_-_99288986 0.22 ENST00000552407.1
ENST00000551613.1
ENST00000548447.1
ENST00000546364.3
ENST00000552748.1
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_+_180897269 0.22 ENST00000367587.1
KIAA1614
KIAA1614
chr2_-_158182410 0.22 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chrX_+_102192200 0.20 ENST00000218249.5
RAB40AL
RAB40A, member RAS oncogene family-like
chr6_+_126240442 0.20 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr3_+_140981456 0.19 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr4_+_54243917 0.19 ENST00000507166.1
FIP1L1
factor interacting with PAPOLA and CPSF1
chr12_-_11036844 0.18 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr1_+_40942887 0.17 ENST00000372706.1
ZFP69
ZFP69 zinc finger protein
chr11_+_63137251 0.17 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chrX_-_24690771 0.17 ENST00000379145.1
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr16_+_20499024 0.17 ENST00000593357.1
AC137056.1
Uncharacterized protein; cDNA FLJ34659 fis, clone KIDNE2018863
chr8_+_42195972 0.16 ENST00000532157.1
ENST00000265421.4
ENST00000520008.1
POLB
polymerase (DNA directed), beta
chr7_-_122840015 0.16 ENST00000194130.2
SLC13A1
solute carrier family 13 (sodium/sulfate symporter), member 1
chr12_-_10251539 0.16 ENST00000420265.2
CLEC1A
C-type lectin domain family 1, member A
chr8_+_24151620 0.16 ENST00000437154.2
ADAM28
ADAM metallopeptidase domain 28
chr2_-_166060571 0.15 ENST00000360093.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr7_-_82792215 0.15 ENST00000333891.9
ENST00000423517.2
PCLO
piccolo presynaptic cytomatrix protein
chr4_-_69111401 0.15 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr12_+_50898881 0.15 ENST00000301180.5
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr10_+_35416090 0.15 ENST00000354759.3
CREM
cAMP responsive element modulator
chr1_-_85930246 0.15 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr12_-_10251603 0.14 ENST00000457018.2
CLEC1A
C-type lectin domain family 1, member A
chr1_+_74701062 0.14 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr12_+_95611516 0.13 ENST00000436874.1
VEZT
vezatin, adherens junctions transmembrane protein
chr11_+_128563652 0.13 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr12_-_10251576 0.13 ENST00000315330.4
CLEC1A
C-type lectin domain family 1, member A
chr1_-_156828810 0.13 ENST00000368195.3
INSRR
insulin receptor-related receptor
chr1_+_47489240 0.13 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr12_-_10282836 0.12 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
CLEC7A
C-type lectin domain family 7, member A
chr21_+_30671690 0.12 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_-_45981138 0.12 ENST00000446994.2
ZMYND8
zinc finger, MYND-type containing 8
chr12_+_95611569 0.12 ENST00000261219.6
ENST00000551472.1
ENST00000552821.1
VEZT
vezatin, adherens junctions transmembrane protein
chr19_-_17375541 0.12 ENST00000252597.3
USHBP1
Usher syndrome 1C binding protein 1
chr3_-_18466026 0.11 ENST00000417717.2
SATB1
SATB homeobox 1
chr2_-_162931052 0.11 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr1_+_185014496 0.11 ENST00000367510.3
RNF2
ring finger protein 2
chr1_-_167883353 0.10 ENST00000545172.1
ADCY10
adenylate cyclase 10 (soluble)
chr1_-_201476220 0.10 ENST00000526723.1
ENST00000524951.1
CSRP1
cysteine and glycine-rich protein 1
chr4_-_40516560 0.10 ENST00000513473.1
RBM47
RNA binding motif protein 47
chr1_-_243418650 0.09 ENST00000522995.1
CEP170
centrosomal protein 170kDa
chr3_-_57583130 0.09 ENST00000303436.6
ARF4
ADP-ribosylation factor 4
chr1_-_119532127 0.09 ENST00000207157.3
TBX15
T-box 15
chr3_-_19988462 0.08 ENST00000344838.4
EFHB
EF-hand domain family, member B
chr1_+_185703513 0.08 ENST00000271588.4
ENST00000367492.2
HMCN1
hemicentin 1
chr11_+_36317830 0.08 ENST00000530639.1
PRR5L
proline rich 5 like
chr17_+_67498538 0.08 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_+_128563948 0.08 ENST00000534087.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr11_-_18548426 0.08 ENST00000357193.3
ENST00000536719.1
TSG101
tumor susceptibility 101
chr2_-_166060382 0.07 ENST00000409101.3
SCN3A
sodium channel, voltage-gated, type III, alpha subunit
chr10_-_28270795 0.07 ENST00000545014.1
ARMC4
armadillo repeat containing 4
chr9_-_74383302 0.07 ENST00000377066.5
TMEM2
transmembrane protein 2
chr1_+_240255166 0.07 ENST00000319653.9
FMN2
formin 2
chr5_+_66254698 0.07 ENST00000405643.1
ENST00000407621.1
ENST00000432426.1
MAST4
microtubule associated serine/threonine kinase family member 4
chrX_+_41192595 0.07 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr5_+_140235469 0.07 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr6_-_11779174 0.07 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr7_-_107443652 0.06 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3
solute carrier family 26 (anion exchanger), member 3
chr12_-_10282742 0.06 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr11_-_85430356 0.06 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr4_+_71457970 0.05 ENST00000322937.6
AMBN
ameloblastin (enamel matrix protein)
chr2_+_223536428 0.05 ENST00000446656.3
MOGAT1
monoacylglycerol O-acyltransferase 1
chr11_-_8964580 0.05 ENST00000325884.1
ASCL3
achaete-scute family bHLH transcription factor 3
chr5_+_170288856 0.04 ENST00000523189.1
RANBP17
RAN binding protein 17
chr4_+_71458012 0.04 ENST00000449493.2
AMBN
ameloblastin (enamel matrix protein)
chrY_+_15016013 0.04 ENST00000360160.4
ENST00000454054.1
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr10_+_35415851 0.04 ENST00000374726.3
CREM
cAMP responsive element modulator
chr6_-_11779014 0.03 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr18_+_7946839 0.03 ENST00000578916.1
PTPRM
protein tyrosine phosphatase, receptor type, M
chr2_-_37899323 0.03 ENST00000295324.3
ENST00000457889.1
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr4_-_70725856 0.03 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr5_+_38148582 0.02 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr4_-_87028478 0.02 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chr4_+_144303093 0.02 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr9_-_85882145 0.02 ENST00000328788.1
FRMD3
FERM domain containing 3
chr1_-_243418621 0.01 ENST00000366544.1
ENST00000366543.1
CEP170
centrosomal protein 170kDa
chr3_+_19988566 0.01 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr14_+_52456327 0.01 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr19_-_17375527 0.01 ENST00000431146.2
ENST00000594190.1
USHBP1
Usher syndrome 1C binding protein 1
chr1_+_228337553 0.00 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX30

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0001300 chronological cell aging(GO:0001300)
0.1 1.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.4 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.8 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.5 GO:0030421 defecation(GO:0030421)
0.1 1.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.2 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.3 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.3 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.3 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.2 GO:1902358 sulfate transmembrane transport(GO:1902358)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0033269 internode region of axon(GO:0033269)
0.0 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.4 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.4 GO:0031093 platelet alpha granule lumen(GO:0031093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.4 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.2 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.3 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.7 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.1 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.8 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation