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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for SOX30
Z-value: 1.19
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Transcription factors associated with SOX30
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX30 | hg19_v2_chr5_-_157079372_157079395 | -0.60 | 4.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr7_+_100770328 Show fit | 1.40 |
ENST00000223095.4
ENST00000445463.2 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
|
| chr3_-_122283424 Show fit | 0.84 |
ENST00000477522.2
ENST00000360356.2 |
poly (ADP-ribose) polymerase family, member 9 |
|
| chr22_-_30970498 Show fit | 0.82 |
ENST00000431313.1
|
galactose-3-O-sulfotransferase 1 |
|
| chr22_+_31488433 Show fit | 0.82 |
ENST00000455608.1
|
smoothelin |
|
| chr5_-_146461027 Show fit | 0.79 |
ENST00000394410.2
ENST00000508267.1 ENST00000504198.1 |
protein phosphatase 2, regulatory subunit B, beta |
|
| chr14_+_101299520 Show fit | 0.64 |
ENST00000455531.1
|
maternally expressed 3 (non-protein coding) |
|
| chr4_+_54243798 Show fit | 0.61 |
ENST00000337488.6
ENST00000358575.5 ENST00000507922.1 |
factor interacting with PAPOLA and CPSF1 |
|
| chr2_-_158182322 Show fit | 0.60 |
ENST00000420719.2
ENST00000409216.1 |
ermin, ERM-like protein |
|
| chr12_-_10588539 Show fit | 0.59 |
ENST00000381902.2
ENST00000381901.1 ENST00000539033.1 |
killer cell lectin-like receptor subfamily C, member 2 Uncharacterized protein |
|
| chr22_-_30970560 Show fit | 0.59 |
ENST00000402369.1
ENST00000406361.1 |
galactose-3-O-sulfotransferase 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX30
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.4 | GO:0001300 | chronological cell aging(GO:0001300) |
| 0.1 | 1.4 | GO:0019375 | galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375) |
| 0.1 | 1.2 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.1 | 0.8 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 0.0 | 0.8 | GO:0070262 | peptidyl-serine dephosphorylation(GO:0070262) |
| 0.0 | 0.6 | GO:0033617 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
| 0.1 | 0.5 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 0.1 | 0.5 | GO:0030421 | defecation(GO:0030421) |
| 0.0 | 0.5 | GO:0070294 | renal sodium ion absorption(GO:0070294) |
| 0.1 | 0.4 | GO:0019442 | tryptophan catabolic process to acetyl-CoA(GO:0019442) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 1.2 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.1 | 0.8 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.0 | 0.8 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.6 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 0.5 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 0.4 | GO:0044233 | ER-mitochondrion membrane contact site(GO:0044233) |
| 0.0 | 0.3 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.0 | 0.3 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.0 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | GO:0050694 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.0 | 1.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.8 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.0 | 0.7 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.1 | 0.6 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.0 | 0.5 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.0 | 0.5 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 0.4 | GO:0016823 | hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823) |
| 0.0 | 0.3 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.0 | 0.3 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 0.8 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 0.5 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 1.4 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.0 | 0.5 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 0.4 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.4 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |