Project
A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for SOX13_SOX12
Z-value: 1.47
Motif logo
Transcription factors associated with SOX13_SOX12
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX12 | hg19_v2_chr20_+_306221_306239 | -1.00 | 2.8e-04 | Click! |
| SOX13 | hg19_v2_chr1_+_204042723_204042784 | -0.96 | 4.3e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_+_39786962 Show fit | 1.70 |
ENST00000333625.2
|
interferon, lambda 1 |
|
| chr17_+_41158742 Show fit | 1.25 |
ENST00000415816.2
ENST00000438323.2 |
interferon-induced protein 35 |
|
| chr5_-_147211226 Show fit | 1.21 |
ENST00000296695.5
|
serine peptidase inhibitor, Kazal type 1 |
|
| chr12_-_10588539 Show fit | 1.18 |
ENST00000381902.2
ENST00000381901.1 ENST00000539033.1 |
killer cell lectin-like receptor subfamily C, member 2 Uncharacterized protein |
|
| chr11_+_5710919 Show fit | 1.12 |
ENST00000379965.3
ENST00000425490.1 |
tripartite motif containing 22 |
|
| chr7_+_100770328 Show fit | 1.10 |
ENST00000223095.4
ENST00000445463.2 |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
|
| chr11_-_327537 Show fit | 1.09 |
ENST00000602735.1
|
interferon induced transmembrane protein 3 |
|
| chr3_+_98699880 Show fit | 1.01 |
ENST00000473756.1
|
long intergenic non-protein coding RNA 973 |
|
| chr11_+_5711010 Show fit | 0.96 |
ENST00000454828.1
|
tripartite motif containing 22 |
|
| chr2_+_33661382 Show fit | 0.87 |
ENST00000402538.3
|
RAS guanyl releasing protein 3 (calcium and DAG-regulated) |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX13_SOX12
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.3 | GO:0060337 | type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357) |
| 0.0 | 2.7 | GO:0060333 | interferon-gamma-mediated signaling pathway(GO:0060333) |
| 0.4 | 1.7 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) |
| 0.0 | 1.6 | GO:0006968 | cellular defense response(GO:0006968) |
| 0.2 | 1.5 | GO:0010751 | negative regulation of nitric oxide mediated signal transduction(GO:0010751) |
| 0.1 | 1.3 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.4 | 1.1 | GO:0001300 | chronological cell aging(GO:0001300) |
| 0.0 | 1.1 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 1.1 | GO:0030318 | melanocyte differentiation(GO:0030318) |
| 0.1 | 1.0 | GO:0042904 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 2.2 | GO:0015030 | Cajal body(GO:0015030) |
| 0.6 | 1.7 | GO:0032002 | interleukin-28 receptor complex(GO:0032002) |
| 0.0 | 1.0 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.0 | 0.8 | GO:0031430 | M band(GO:0031430) |
| 0.0 | 0.7 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 0.6 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 0.6 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 0.6 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.0 | 0.5 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.9 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 1.2 | GO:0017159 | pantetheine hydrolase activity(GO:0017159) |
| 0.0 | 1.1 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 1.1 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.1 | 1.0 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.0 | 0.8 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.0 | 0.8 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.1 | 0.7 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
| 0.0 | 0.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 0.6 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 1.1 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.0 | 1.1 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.6 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.0 | 0.6 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.0 | 0.5 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.0 | 0.4 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.2 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.0 | 0.2 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 0.2 | PID IGF1 PATHWAY | IGF1 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.7 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 0.8 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 0.8 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.6 | REACTOME LIPOPROTEIN METABOLISM | Genes involved in Lipoprotein metabolism |
| 0.0 | 0.6 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.5 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.4 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.0 | 0.4 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.0 | 0.4 | REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Extrinsic Pathway for Apoptosis |