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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SOX10_SOX15

Z-value: 1.02

Motif logo

Transcription factors associated with SOX10_SOX15

Gene Symbol Gene ID Gene Info
ENSG00000100146.12 SRY-box transcription factor 10
ENSG00000129194.3 SRY-box transcription factor 15

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX15hg19_v2_chr17_-_7493390_7493488-0.168.4e-01Click!

Activity profile of SOX10_SOX15 motif

Sorted Z-values of SOX10_SOX15 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_76649546 1.09 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
GTPase activating protein (SH3 domain) binding protein 2
chr12_+_95611536 0.99 ENST00000549002.1
vezatin, adherens junctions transmembrane protein
chr6_+_64282447 0.92 ENST00000370650.2
ENST00000578299.1
protein tyrosine phosphatase type IVA, member 1
chr5_+_31193847 0.86 ENST00000514738.1
ENST00000265071.2
cadherin 6, type 2, K-cadherin (fetal kidney)
chr3_-_148939598 0.80 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr12_-_42631529 0.71 ENST00000548917.1
YY1 associated factor 2
chr2_-_37501692 0.68 ENST00000443977.1
protein kinase D3
chr1_-_26233423 0.64 ENST00000357865.2
stathmin 1
chr22_-_39052300 0.64 ENST00000355830.6
family with sequence similarity 227, member A
chr10_-_75351088 0.63 ENST00000451492.1
ENST00000413442.1
ubiquitin specific peptidase 54
chr15_+_57210961 0.57 ENST00000557843.1
transcription factor 12
chr9_-_123476612 0.54 ENST00000426959.1
multiple EGF-like-domains 9
chr14_-_50583271 0.53 ENST00000395860.2
ENST00000395859.2
valosin containing protein lysine (K) methyltransferase
chrX_+_80457442 0.53 ENST00000373212.5
SH3 domain binding glutamic acid-rich protein like
chr5_+_149865377 0.53 ENST00000522491.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_-_167813672 0.51 ENST00000470487.1
golgi integral membrane protein 4
chr4_+_95128748 0.51 ENST00000359052.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_+_95128996 0.51 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr1_+_228337553 0.50 ENST00000366714.2
gap junction protein, gamma 2, 47kDa
chr14_-_65409438 0.49 ENST00000557049.1
glutathione peroxidase 2 (gastrointestinal)
chr4_+_95129061 0.48 ENST00000354268.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr4_-_140477910 0.47 ENST00000404104.3
SET domain containing (lysine methyltransferase) 7
chr12_+_8849773 0.47 ENST00000541044.1
ribosomal modification protein rimK-like family member B
chr14_-_31495569 0.46 ENST00000357479.5
ENST00000355683.5
striatin, calmodulin binding protein 3
chr6_+_83777374 0.43 ENST00000349129.2
ENST00000237163.5
ENST00000536812.1
dopey family member 1
chr20_+_60718785 0.41 ENST00000421564.1
ENST00000450482.1
ENST00000331758.3
synovial sarcoma translocation gene on chromosome 18-like 1
chr11_-_8892464 0.41 ENST00000527347.1
ENST00000526241.1
ENST00000526126.1
ENST00000530938.1
ENST00000526057.1
suppression of tumorigenicity 5
chr14_-_80678512 0.40 ENST00000553968.1
deiodinase, iodothyronine, type II
chr4_-_140477928 0.38 ENST00000274031.3
SET domain containing (lysine methyltransferase) 7
chr6_-_64029879 0.38 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
lengsin, lens protein with glutamine synthetase domain
chr2_+_70056762 0.38 ENST00000282570.3
germ cell-less, spermatogenesis associated 1
chr15_+_52043813 0.36 ENST00000435126.2
tropomodulin 2 (neuronal)
chr14_-_65409502 0.36 ENST00000389614.5
glutathione peroxidase 2 (gastrointestinal)
chr6_-_134861089 0.35 ENST00000606039.1
RP11-557H15.4
chr15_+_57210818 0.34 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
transcription factor 12
chrX_-_45629661 0.33 ENST00000602507.1
ENST00000602461.1
RP6-99M1.2
chr3_+_151986709 0.33 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chrX_-_63425561 0.32 ENST00000374869.3
ENST00000330258.3
APC membrane recruitment protein 1
chr10_-_99094458 0.32 ENST00000371019.2
frequently rearranged in advanced T-cell lymphomas 2
chr1_-_93645818 0.32 ENST00000370280.1
ENST00000479918.1
transmembrane emp24 protein transport domain containing 5
chr3_-_123339343 0.32 ENST00000578202.1
myosin light chain kinase
chr3_+_189349162 0.31 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
tumor protein p63
chr1_-_65533390 0.31 ENST00000448344.1
RP4-535B20.1
chrX_-_131352152 0.30 ENST00000342983.2
RAP2C, member of RAS oncogene family
chr14_+_38065052 0.30 ENST00000556845.1
tetratricopeptide repeat domain 6
chr5_-_138718973 0.30 ENST00000353963.3
ENST00000348729.3
solute carrier family 23 (ascorbic acid transporter), member 1
chr11_-_76155618 0.30 ENST00000530759.1
RP11-111M22.3
chr12_+_50479101 0.30 ENST00000551966.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr1_+_93913713 0.29 ENST00000604705.1
ENST00000370253.2
formin binding protein 1-like
chr15_+_52311398 0.29 ENST00000261845.5
mitogen-activated protein kinase 6
chr2_-_204400013 0.28 ENST00000374489.2
ENST00000374488.2
ENST00000308091.4
ENST00000453034.1
ENST00000420371.1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr15_+_52043758 0.28 ENST00000249700.4
ENST00000539962.2
tropomodulin 2 (neuronal)
chr3_-_27525826 0.28 ENST00000454389.1
ENST00000440156.1
ENST00000437179.1
ENST00000446700.1
ENST00000455077.1
ENST00000435667.2
ENST00000388777.4
ENST00000425128.2
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr7_+_23146271 0.28 ENST00000545771.1
kelch-like family member 7
chr6_+_122720681 0.28 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr4_+_76649797 0.27 ENST00000538159.1
ENST00000514213.2
USO1 vesicle transport factor
chr3_+_181429704 0.27 ENST00000431565.2
ENST00000325404.1
SRY (sex determining region Y)-box 2
chr4_+_154387480 0.27 ENST00000409663.3
ENST00000440693.1
ENST00000409959.3
KIAA0922
chr6_+_43968306 0.27 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
chromosome 6 open reading frame 223
chr13_-_41593425 0.26 ENST00000239882.3
E74-like factor 1 (ets domain transcription factor)
chr9_-_123476719 0.26 ENST00000373930.3
multiple EGF-like-domains 9
chr16_+_30934376 0.26 ENST00000562798.1
ENST00000471231.2
F-box and leucine-rich repeat protein 19
chr17_-_49124230 0.26 ENST00000510283.1
ENST00000510855.1
sperm associated antigen 9
chr2_+_27070964 0.26 ENST00000288699.6
dihydropyrimidinase-like 5
chr15_+_101402041 0.26 ENST00000558475.1
ENST00000558641.1
ENST00000559673.1
RP11-66B24.1
chr6_-_111888474 0.25 ENST00000368735.1
TRAF3 interacting protein 2
chr18_-_74728998 0.24 ENST00000359645.3
ENST00000397875.3
ENST00000397869.3
ENST00000578193.1
ENST00000578873.1
ENST00000397866.4
ENST00000528160.1
ENST00000527041.1
ENST00000526111.1
ENST00000397865.5
ENST00000382582.3
myelin basic protein
chr16_+_53242350 0.24 ENST00000565442.1
chromodomain helicase DNA binding protein 9
chr17_+_27920486 0.24 ENST00000394859.3
ankyrin repeat domain 13B
chr4_+_90033968 0.24 ENST00000317005.2
tigger transposable element derived 2
chr2_-_118943930 0.23 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
chr4_+_76649753 0.23 ENST00000603759.1
USO1 vesicle transport factor
chr5_+_149865838 0.23 ENST00000519157.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr10_+_114710211 0.23 ENST00000349937.2
ENST00000369397.4
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr8_+_21777159 0.23 ENST00000434536.1
ENST00000252512.9
exportin 7
chr11_-_66445219 0.23 ENST00000525754.1
ENST00000531969.1
ENST00000524637.1
ENST00000531036.2
ENST00000310046.4
RNA binding motif protein 4B
chr4_-_164534657 0.23 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr14_-_71107921 0.23 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr5_+_137514834 0.22 ENST00000508792.1
ENST00000504621.1
kinesin family member 20A
chr2_-_85625857 0.22 ENST00000453973.1
capping protein (actin filament), gelsolin-like
chr12_-_58145889 0.22 ENST00000547853.1
cyclin-dependent kinase 4
chr6_+_119215308 0.22 ENST00000229595.5
anti-silencing function 1A histone chaperone
chr15_-_80695917 0.22 ENST00000559008.1
Uncharacterized protein
chr2_+_32288657 0.22 ENST00000345662.1
spastin
chr4_+_113152978 0.22 ENST00000309703.6
adaptor-related protein complex 1 associated regulatory protein
chr2_-_70475701 0.22 ENST00000282574.4
TIA1 cytotoxic granule-associated RNA binding protein
chr12_+_11081828 0.22 ENST00000381847.3
ENST00000396400.3
proline-rich protein HaeIII subfamily 2
chr16_-_15736881 0.22 ENST00000540441.2
KIAA0430
chr2_+_69240302 0.22 ENST00000303714.4
anthrax toxin receptor 1
chr15_-_52944231 0.22 ENST00000546305.2
family with sequence similarity 214, member A
chr14_-_67981916 0.21 ENST00000357461.2
transmembrane protein 229B
chr3_-_57583052 0.21 ENST00000496292.1
ENST00000489843.1
ADP-ribosylation factor 4
chr3_-_148939835 0.21 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr10_+_114709999 0.21 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr7_+_102553430 0.21 ENST00000339431.4
ENST00000249377.4
leucine rich repeat containing 17
chr2_+_181845843 0.21 ENST00000602710.1
ubiquitin-conjugating enzyme E2E 3
chr10_-_14613968 0.21 ENST00000488576.1
ENST00000472095.1
family with sequence similarity 107, member B
chr11_-_111781610 0.21 ENST00000525823.1
crystallin, alpha B
chr1_-_114355083 0.20 ENST00000261441.5
round spermatid basic protein 1
chrX_-_106960285 0.20 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr4_+_106067943 0.20 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
tet methylcytosine dioxygenase 2
chr16_+_53483983 0.20 ENST00000544545.1
retinoblastoma-like 2 (p130)
chr16_-_30798492 0.20 ENST00000262525.4
zinc finger protein 629
chr8_-_80993010 0.20 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
tumor protein D52
chr1_+_183774240 0.20 ENST00000360851.3
ral guanine nucleotide dissociation stimulator-like 1
chr1_+_93645314 0.20 ENST00000343253.7
coiled-coil domain containing 18
chr10_-_735553 0.20 ENST00000280886.6
ENST00000423550.1
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr10_-_70092671 0.20 ENST00000358769.2
ENST00000432941.1
ENST00000495025.2
phenazine biosynthesis-like protein domain containing
chr3_-_48470838 0.20 ENST00000358459.4
ENST00000358536.4
plexin B1
chr5_-_111092930 0.20 ENST00000257435.7
neuronal regeneration related protein
chr5_-_14871866 0.20 ENST00000284268.6
ANKH inorganic pyrophosphate transport regulator
chr6_+_30689350 0.20 ENST00000330914.3
tubulin, beta class I
chr20_+_48884002 0.19 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
chr2_-_70475730 0.19 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1 cytotoxic granule-associated RNA binding protein
chr7_+_74379083 0.19 ENST00000361825.7
GATS protein-like 1
chr19_+_13228917 0.19 ENST00000586171.1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr10_-_70092635 0.19 ENST00000309049.4
phenazine biosynthesis-like protein domain containing
chr17_-_46623441 0.19 ENST00000330070.4
homeobox B2
chr19_+_1249869 0.19 ENST00000591446.2
midnolin
chr12_-_71551868 0.19 ENST00000247829.3
tetraspanin 8
chr5_+_137514687 0.19 ENST00000394894.3
kinesin family member 20A
chr2_+_120517174 0.18 ENST00000263708.2
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr12_-_2966193 0.18 ENST00000382678.3
Uncharacterized protein ENSP00000372125
chr11_-_111781454 0.18 ENST00000533280.1
crystallin, alpha B
chr22_+_31742875 0.18 ENST00000504184.2
CDNA FLJ20464 fis, clone KAT06158; HCG1777549; Uncharacterized protein
chrX_-_135962876 0.18 ENST00000431446.3
ENST00000570135.1
ENST00000320676.7
ENST00000562646.1
RNA binding motif protein, X-linked
chr5_-_135701164 0.18 ENST00000355180.3
ENST00000426057.2
ENST00000513104.1
transient receptor potential cation channel, subfamily C, member 7
chr1_+_68150744 0.18 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr12_-_105478339 0.17 ENST00000424857.2
ENST00000258494.9
aldehyde dehydrogenase 1 family, member L2
chr7_+_116660246 0.17 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
suppression of tumorigenicity 7
chr12_+_53443963 0.17 ENST00000546602.1
ENST00000552570.1
ENST00000549700.1
tensin like C1 domain containing phosphatase (tensin 2)
chr2_-_47572105 0.17 ENST00000419035.1
ENST00000448713.1
ENST00000450550.1
ENST00000413185.2
AC073283.4
chr5_-_111092873 0.17 ENST00000509025.1
ENST00000515855.1
neuronal regeneration related protein
chr6_+_151358048 0.17 ENST00000450635.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr12_+_53443680 0.17 ENST00000314250.6
ENST00000451358.1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_149688971 0.17 ENST00000498307.1
ENST00000489155.1
profilin 2
chr4_+_113152881 0.17 ENST00000274000.5
adaptor-related protein complex 1 associated regulatory protein
chr14_-_67981870 0.16 ENST00000555994.1
transmembrane protein 229B
chr6_+_108881012 0.16 ENST00000343882.6
forkhead box O3
chr9_+_103235365 0.16 ENST00000374879.4
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_+_30185406 0.16 ENST00000324489.5
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr2_+_32288725 0.16 ENST00000315285.3
spastin
chr14_-_91884115 0.16 ENST00000389857.6
coiled-coil domain containing 88C
chr8_-_17579726 0.16 ENST00000381861.3
microtubule associated tumor suppressor 1
chr12_-_102591604 0.16 ENST00000329406.4
pro-melanin-concentrating hormone
chr7_+_29234101 0.16 ENST00000435288.2
chimerin 2
chr14_-_51027838 0.16 ENST00000555216.1
mitogen-activated protein kinase kinase kinase kinase 5
chr5_+_78532003 0.15 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr1_-_204436344 0.15 ENST00000367184.2
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
chr21_-_40720995 0.15 ENST00000380749.5
high mobility group nucleosome binding domain 1
chr22_-_23484246 0.15 ENST00000216036.4
rhabdoid tumor deletion region gene 1
chr7_-_32111009 0.15 ENST00000396184.3
ENST00000396189.2
ENST00000321453.7
phosphodiesterase 1C, calmodulin-dependent 70kDa
chr1_-_6479963 0.15 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
hes family bHLH transcription factor 2
chr1_-_151431909 0.14 ENST00000361398.3
ENST00000271715.2
pogo transposable element with ZNF domain
chrX_+_37639302 0.14 ENST00000545017.1
ENST00000536160.1
cytochrome b-245, beta polypeptide
chr6_+_87865262 0.14 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
zinc finger protein 292
chr18_+_20494078 0.14 ENST00000579124.1
ENST00000577588.1
ENST00000582354.1
ENST00000581819.1
retinoblastoma binding protein 8
chrX_+_129473859 0.14 ENST00000424447.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_-_37899323 0.14 ENST00000295324.3
ENST00000457889.1
CDC42 effector protein (Rho GTPase binding) 3
chr11_-_102323489 0.14 ENST00000361236.3
transmembrane protein 123
chr5_+_137514403 0.14 ENST00000513276.1
kinesin family member 20A
chr5_+_65222438 0.14 ENST00000380938.2
erbb2 interacting protein
chr6_-_29527702 0.13 ENST00000377050.4
ubiquitin D
chr21_-_16437126 0.13 ENST00000318948.4
nuclear receptor interacting protein 1
chr11_-_102323740 0.13 ENST00000398136.2
transmembrane protein 123
chr21_-_16437255 0.13 ENST00000400199.1
ENST00000400202.1
nuclear receptor interacting protein 1
chr9_+_128510454 0.13 ENST00000491787.3
ENST00000447726.2
pre-B-cell leukemia homeobox 3
chr9_-_119162885 0.13 ENST00000445861.2
PAPPA antisense RNA 1
chr15_+_58724184 0.13 ENST00000433326.2
lipase, hepatic
chr1_+_166808667 0.13 ENST00000537173.1
ENST00000536514.1
ENST00000449930.1
pogo transposable element with KRAB domain
chr17_+_53046096 0.13 ENST00000376352.2
ENST00000299341.4
ENST00000405898.1
ENST00000434978.2
ENST00000398391.2
syntaxin binding protein 4
chr7_-_94953878 0.13 ENST00000222381.3
paraoxonase 1
chr21_-_40720974 0.13 ENST00000380748.1
high mobility group nucleosome binding domain 1
chr6_+_74405804 0.13 ENST00000287097.5
CD109 molecule
chr7_+_73868439 0.13 ENST00000424337.2
GTF2I repeat domain containing 1
chr6_+_74405501 0.13 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr12_+_104359576 0.13 ENST00000392872.3
ENST00000436021.2
thymine-DNA glycosylase
chr10_+_97803151 0.13 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
cyclin J
chr3_-_167813132 0.13 ENST00000309027.4
golgi integral membrane protein 4
chr3_-_52719888 0.13 ENST00000458294.1
polybromo 1
chr5_-_141338377 0.13 ENST00000510041.1
protocadherin 12
chr20_-_52645231 0.13 ENST00000448484.1
breast carcinoma amplified sequence 1
chr5_-_138780159 0.13 ENST00000512473.1
ENST00000515581.1
ENST00000515277.1
DnaJ (Hsp40) homolog, subfamily C, member 18
chrX_+_70443050 0.13 ENST00000361726.6
gap junction protein, beta 1, 32kDa
chr4_-_5890145 0.13 ENST00000397890.2
collapsin response mediator protein 1
chr21_+_30671690 0.12 ENST00000399921.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr12_-_12419703 0.12 ENST00000543091.1
ENST00000261349.4
low density lipoprotein receptor-related protein 6
chr14_-_50999190 0.12 ENST00000557390.1
mitogen-activated protein kinase kinase kinase kinase 5
chr14_+_97263641 0.12 ENST00000216639.3
vaccinia related kinase 1
chr4_-_40516560 0.12 ENST00000513473.1
RNA binding motif protein 47
chr11_-_111781554 0.12 ENST00000526167.1
ENST00000528961.1
crystallin, alpha B
chrX_+_84498989 0.12 ENST00000395402.1
zinc finger protein 711
chr21_+_35553045 0.12 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
long intergenic non-protein coding RNA 310
chr10_-_14614311 0.12 ENST00000479731.1
ENST00000468492.1
family with sequence similarity 107, member B
chr15_+_62359175 0.12 ENST00000355522.5
C2 calcium-dependent domain containing 4A
chr7_-_15601595 0.12 ENST00000342526.3
alkylglycerol monooxygenase
chr11_-_64013663 0.12 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_86564740 0.12 ENST00000540790.1
ENST00000428491.1
receptor accessory protein 1
chr11_-_117166276 0.12 ENST00000510630.1
ENST00000392937.6
beta-site APP-cleaving enzyme 1
chr14_-_95236551 0.12 ENST00000238558.3
goosecoid homeobox

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX10_SOX15

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060996 dendritic spine development(GO:0060996) regulation of dendritic spine development(GO:0060998) positive regulation of dendritic spine development(GO:0060999)
0.1 0.6 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 0.4 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.4 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.3 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.6 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.1 0.7 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.6 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.2 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.7 GO:0006477 protein sulfation(GO:0006477)
0.1 0.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.4 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.1 0.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 1.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:0007388 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.4 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.2 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 1.0 GO:0006825 copper ion transport(GO:0006825)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.5 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.3 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.1 GO:1903452 regulation of G1 to G0 transition(GO:1903450) positive regulation of G1 to G0 transition(GO:1903452)
0.0 0.1 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.0 0.4 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.1 GO:1902811 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.4 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0046661 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) male sex differentiation(GO:0046661)
0.0 0.3 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0090166 histone-threonine phosphorylation(GO:0035405) Golgi disassembly(GO:0090166)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:1904247 positive regulation of polynucleotide adenylyltransferase activity(GO:1904247)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.0 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.2 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.1 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.0 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.1 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.3 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.1 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.4 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.3 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.5 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 1.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.7 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 1.3 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290) Flemming body(GO:0090543)
0.0 0.1 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 0.8 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.3 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.4 GO:0004356 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 0.3 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 1.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.3 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.5 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.4 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.4 GO:0016279 protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.1 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.6 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.1 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.5 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 1.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade