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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SMAD3

Z-value: 0.71

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Transcription factors associated with SMAD3

Gene Symbol Gene ID Gene Info
SMAD3
ENSG00000166949.11 SMAD family member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SMAD3hg19_v2_chr15_+_67390920_67391046-0.981.9e-02Click!

Activity profile of SMAD3 motif

Sorted Z-values of SMAD3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_90712520 0.97 ENST00000224784.6
ACTA2
actin, alpha 2, smooth muscle, aorta
chr14_-_100625932 0.79 ENST00000553834.1
DEGS2
delta(4)-desaturase, sphingolipid 2
chr22_-_36013368 0.56 ENST00000442617.1
ENST00000397326.2
ENST00000397328.1
ENST00000451685.1
MB
myoglobin
chr19_-_36304201 0.56 ENST00000301175.3
PRODH2
proline dehydrogenase (oxidase) 2
chr6_-_26189304 0.45 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr5_-_79950775 0.43 ENST00000439211.2
DHFR
dihydrofolate reductase
chr1_+_205682497 0.41 ENST00000598338.1
AC119673.1
AC119673.1
chr13_-_60738003 0.40 ENST00000400330.1
ENST00000400324.4
DIAPH3
diaphanous-related formin 3
chr11_+_45376922 0.39 ENST00000524410.1
ENST00000524488.1
ENST00000524565.1
RP11-430H10.1
RP11-430H10.1
chr10_-_102046417 0.38 ENST00000370372.2
BLOC1S2
biogenesis of lysosomal organelles complex-1, subunit 2
chr7_+_139529040 0.35 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr6_+_26124373 0.34 ENST00000377791.2
ENST00000602637.1
HIST1H2AC
histone cluster 1, H2ac
chr7_+_139528952 0.34 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1
thromboxane A synthase 1 (platelet)
chr11_+_72983246 0.33 ENST00000393590.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_-_71781096 0.33 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr20_-_23030296 0.31 ENST00000377103.2
THBD
thrombomodulin
chr6_-_27100529 0.29 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
HIST1H2BJ
histone cluster 1, H2bj
chr12_-_110906027 0.29 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN3
GPN-loop GTPase 3
chr6_-_27806117 0.29 ENST00000330180.2
HIST1H2AK
histone cluster 1, H2ak
chr6_-_26285737 0.28 ENST00000377727.1
ENST00000289352.1
HIST1H4H
histone cluster 1, H4h
chr17_-_39165366 0.28 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr7_-_55620433 0.26 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr11_+_117070037 0.25 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr6_+_26204825 0.24 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr1_-_36906474 0.24 ENST00000433045.2
OSCP1
organic solute carrier partner 1
chr7_-_120497178 0.22 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr1_-_21113765 0.21 ENST00000438032.1
ENST00000424732.1
ENST00000437575.1
HP1BP3
heterochromatin protein 1, binding protein 3
chr1_+_200863949 0.21 ENST00000413687.2
C1orf106
chromosome 1 open reading frame 106
chr14_-_65409502 0.21 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr6_+_27100811 0.21 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chr16_+_19098178 0.20 ENST00000568032.1
RP11-626G11.4
RP11-626G11.4
chr5_+_140625147 0.19 ENST00000231173.3
PCDHB15
protocadherin beta 15
chr6_+_116937636 0.19 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A
radial spoke head 4 homolog A (Chlamydomonas)
chr5_+_52776228 0.19 ENST00000256759.3
FST
follistatin
chr19_+_34850385 0.18 ENST00000587521.2
ENST00000587384.1
ENST00000592277.1
GPI
glucose-6-phosphate isomerase
chr10_+_94451574 0.18 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr11_-_12031273 0.18 ENST00000525493.1
DKK3
dickkopf WNT signaling pathway inhibitor 3
chr6_+_30850862 0.18 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr18_+_44526786 0.18 ENST00000245121.5
ENST00000356157.7
KATNAL2
katanin p60 subunit A-like 2
chr19_-_13947099 0.17 ENST00000587762.1
MIR24-2
microRNA 24-2
chr11_-_61101247 0.17 ENST00000543627.1
DDB1
damage-specific DNA binding protein 1, 127kDa
chr6_-_133119668 0.17 ENST00000275227.4
ENST00000538764.1
SLC18B1
solute carrier family 18, subfamily B, member 1
chr14_+_53196872 0.17 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr5_-_41870621 0.16 ENST00000196371.5
OXCT1
3-oxoacid CoA transferase 1
chr5_+_140566 0.16 ENST00000502646.1
PLEKHG4B
pleckstrin homology domain containing, family G (with RhoGef domain) member 4B
chr20_+_24449821 0.16 ENST00000376862.3
SYNDIG1
synapse differentiation inducing 1
chr1_-_156399184 0.16 ENST00000368243.1
ENST00000357975.4
ENST00000310027.5
ENST00000400991.2
C1orf61
chromosome 1 open reading frame 61
chr15_+_71184931 0.16 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr1_-_9129735 0.16 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr3_-_14220068 0.15 ENST00000449060.2
ENST00000511155.1
XPC
xeroderma pigmentosum, complementation group C
chr14_-_65409438 0.15 ENST00000557049.1
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr20_+_44036620 0.15 ENST00000372710.3
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr12_+_49212514 0.14 ENST00000301050.2
ENST00000548279.1
ENST00000547230.1
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr2_-_45162783 0.14 ENST00000432125.2
RP11-89K21.1
RP11-89K21.1
chr1_+_90287480 0.14 ENST00000394593.3
LRRC8D
leucine rich repeat containing 8 family, member D
chr20_+_55926625 0.14 ENST00000452119.1
RAE1
ribonucleic acid export 1
chr6_+_139349817 0.14 ENST00000367660.3
ABRACL
ABRA C-terminal like
chr11_-_34938039 0.14 ENST00000395787.3
APIP
APAF1 interacting protein
chr14_+_96858433 0.13 ENST00000267584.4
AK7
adenylate kinase 7
chr20_+_55926566 0.13 ENST00000411894.1
ENST00000429339.1
RAE1
ribonucleic acid export 1
chr7_+_133261209 0.12 ENST00000545148.1
EXOC4
exocyst complex component 4
chr15_+_63796779 0.12 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
USP3
ubiquitin specific peptidase 3
chr9_+_5890802 0.11 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
MLANA
melan-A
chr17_-_34195889 0.11 ENST00000311880.2
C17orf66
chromosome 17 open reading frame 66
chr17_-_34195862 0.11 ENST00000592980.1
ENST00000587626.1
C17orf66
chromosome 17 open reading frame 66
chr9_+_37485932 0.11 ENST00000377798.4
ENST00000442009.2
POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr6_-_41888814 0.11 ENST00000409060.1
ENST00000265350.4
MED20
mediator complex subunit 20
chr12_-_9913489 0.11 ENST00000228434.3
ENST00000536709.1
CD69
CD69 molecule
chr6_+_30850697 0.11 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr20_+_44036900 0.11 ENST00000443296.1
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_-_41196458 0.10 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr6_-_27775694 0.10 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr6_+_27861190 0.10 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr15_+_63889552 0.10 ENST00000360587.2
FBXL22
F-box and leucine-rich repeat protein 22
chr16_-_11723066 0.09 ENST00000576036.1
LITAF
lipopolysaccharide-induced TNF factor
chr16_-_15180257 0.09 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr9_+_37486005 0.09 ENST00000377792.3
POLR1E
polymerase (RNA) I polypeptide E, 53kDa
chr19_+_42724423 0.09 ENST00000301215.3
ENST00000597945.1
ZNF526
zinc finger protein 526
chr11_+_124824000 0.09 ENST00000529051.1
ENST00000344762.5
CCDC15
coiled-coil domain containing 15
chr16_-_3350614 0.09 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr16_+_30483962 0.09 ENST00000356798.6
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr14_+_96858454 0.09 ENST00000555570.1
AK7
adenylate kinase 7
chr16_+_699319 0.08 ENST00000549091.1
ENST00000293879.4
WDR90
WD repeat domain 90
chr4_+_2813946 0.08 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr6_+_30851205 0.08 ENST00000515881.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr15_-_83316711 0.08 ENST00000568128.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr2_+_220110177 0.07 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
STK16
serine/threonine kinase 16
chr9_+_44867571 0.07 ENST00000377548.2
RP11-160N1.10
RP11-160N1.10
chr19_-_37958086 0.07 ENST00000592490.1
ENST00000392149.2
ZNF569
zinc finger protein 569
chr12_+_65563329 0.07 ENST00000308330.2
LEMD3
LEM domain containing 3
chrX_-_2847366 0.07 ENST00000381154.1
ARSD
arylsulfatase D
chr2_-_220110111 0.07 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L
galactosidase, beta 1-like
chr16_-_57798253 0.07 ENST00000565270.1
KIFC3
kinesin family member C3
chr16_+_30484054 0.06 ENST00000564118.1
ENST00000454514.2
ENST00000433423.2
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr11_-_34937858 0.06 ENST00000278359.5
APIP
APAF1 interacting protein
chr5_+_79950463 0.06 ENST00000265081.6
MSH3
mutS homolog 3
chr22_-_46644182 0.06 ENST00000404583.1
ENST00000404744.1
CDPF1
cysteine-rich, DPF motif domain containing 1
chr3_+_12838161 0.06 ENST00000456430.2
CAND2
cullin-associated and neddylation-dissociated 2 (putative)
chr5_-_68628543 0.06 ENST00000396496.2
ENST00000511257.1
ENST00000383374.2
CCDC125
coiled-coil domain containing 125
chr6_+_139349903 0.06 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr11_+_46383121 0.06 ENST00000454345.1
DGKZ
diacylglycerol kinase, zeta
chr18_+_55862622 0.06 ENST00000456173.2
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_+_12008986 0.06 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_+_59762642 0.06 ENST00000371218.4
ENST00000303721.7
FGGY
FGGY carbohydrate kinase domain containing
chr14_-_24551137 0.05 ENST00000396995.1
NRL
neural retina leucine zipper
chr7_-_22862448 0.05 ENST00000358435.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr2_-_220110187 0.05 ENST00000295759.7
ENST00000392089.2
GLB1L
galactosidase, beta 1-like
chr11_+_116700600 0.05 ENST00000227667.3
APOC3
apolipoprotein C-III
chr16_+_30484021 0.05 ENST00000358164.5
ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr21_+_33031935 0.05 ENST00000270142.6
ENST00000389995.4
SOD1
superoxide dismutase 1, soluble
chr20_+_55926274 0.05 ENST00000371242.2
ENST00000527947.1
RAE1
ribonucleic acid export 1
chrX_-_62571220 0.05 ENST00000374884.2
SPIN4
spindlin family, member 4
chr11_+_116700614 0.05 ENST00000375345.1
APOC3
apolipoprotein C-III
chr1_-_9129631 0.04 ENST00000377414.3
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr19_-_50143452 0.04 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr8_+_128747661 0.04 ENST00000259523.6
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr3_-_123710893 0.04 ENST00000467907.1
ENST00000459660.1
ENST00000495093.1
ENST00000460743.1
ENST00000405845.3
ENST00000484329.1
ENST00000479867.1
ENST00000496145.1
ROPN1
rhophilin associated tail protein 1
chr15_-_82338460 0.04 ENST00000558133.1
ENST00000329713.4
MEX3B
mex-3 RNA binding family member B
chr6_-_99842041 0.04 ENST00000254759.3
ENST00000369242.1
COQ3
coenzyme Q3 methyltransferase
chr4_-_39033963 0.04 ENST00000381938.3
TMEM156
transmembrane protein 156
chrX_-_62571187 0.04 ENST00000335144.3
SPIN4
spindlin family, member 4
chr7_-_22862406 0.04 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr8_+_38585704 0.04 ENST00000519416.1
ENST00000520615.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr15_-_22473353 0.04 ENST00000557788.2
IGHV4OR15-8
immunoglobulin heavy variable 4/OR15-8 (non-functional)
chr19_+_36132631 0.04 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr8_-_80942061 0.04 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr4_+_2814011 0.04 ENST00000502260.1
ENST00000435136.2
SH3BP2
SH3-domain binding protein 2
chr5_+_167913450 0.04 ENST00000231572.3
ENST00000538719.1
RARS
arginyl-tRNA synthetase
chr5_+_55147205 0.03 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
IL31RA
interleukin 31 receptor A
chr4_+_186990298 0.03 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr12_+_67663056 0.03 ENST00000545606.1
CAND1
cullin-associated and neddylation-dissociated 1
chr1_+_207039154 0.03 ENST00000367096.3
ENST00000391930.2
IL20
interleukin 20
chr12_+_110906169 0.03 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr15_-_83315874 0.03 ENST00000569257.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr1_-_160040038 0.03 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr1_+_193091080 0.03 ENST00000367435.3
CDC73
cell division cycle 73
chr12_-_110939870 0.03 ENST00000447578.2
ENST00000546588.1
ENST00000360579.7
ENST00000549970.1
ENST00000549578.1
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr1_-_11042094 0.03 ENST00000377004.4
ENST00000377008.4
C1orf127
chromosome 1 open reading frame 127
chr17_-_26733604 0.03 ENST00000584426.1
ENST00000584995.1
SLC46A1
solute carrier family 46 (folate transporter), member 1
chr17_+_12859080 0.03 ENST00000583608.1
ARHGAP44
Rho GTPase activating protein 44
chr19_-_42006539 0.03 ENST00000597702.1
ENST00000588495.1
ENST00000595837.1
ENST00000594315.1
AC011526.1
AC011526.1
chr7_-_27169801 0.03 ENST00000511914.1
HOXA4
homeobox A4
chr8_+_22250334 0.02 ENST00000520832.1
SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr6_-_27114577 0.02 ENST00000356950.1
ENST00000396891.4
HIST1H2BK
histone cluster 1, H2bk
chr14_+_24600484 0.02 ENST00000267426.5
FITM1
fat storage-inducing transmembrane protein 1
chr3_+_141103634 0.02 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr16_+_618837 0.02 ENST00000409439.2
PIGQ
phosphatidylinositol glycan anchor biosynthesis, class Q
chr2_+_75061108 0.02 ENST00000290573.2
HK2
hexokinase 2
chr9_-_43133544 0.02 ENST00000254835.2
ANKRD20A3
ankyrin repeat domain 20 family, member A3
chr6_-_41888843 0.02 ENST00000434077.1
ENST00000409312.1
MED20
mediator complex subunit 20
chr11_+_113258495 0.02 ENST00000303941.3
ANKK1
ankyrin repeat and kinase domain containing 1
chr2_-_75788424 0.01 ENST00000410071.1
EVA1A
eva-1 homolog A (C. elegans)
chr20_-_60795296 0.01 ENST00000340177.5
HRH3
histamine receptor H3
chr9_-_14322319 0.01 ENST00000606230.1
NFIB
nuclear factor I/B
chr22_+_20877924 0.01 ENST00000445189.1
MED15
mediator complex subunit 15
chr15_+_68117872 0.01 ENST00000380035.2
ENST00000389002.1
SKOR1
SKI family transcriptional corepressor 1
chr8_+_38586068 0.01 ENST00000443286.2
ENST00000520340.1
ENST00000518415.1
TACC1
transforming, acidic coiled-coil containing protein 1
chr12_-_323689 0.01 ENST00000428720.1
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr19_-_55691614 0.01 ENST00000592470.1
ENST00000354308.3
SYT5
synaptotagmin V
chr12_+_14927270 0.01 ENST00000544848.1
H2AFJ
H2A histone family, member J
chr15_+_51633826 0.01 ENST00000335449.6
GLDN
gliomedin
chr18_+_55862873 0.01 ENST00000588494.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr6_-_11807277 0.01 ENST00000379415.2
ADTRP
androgen-dependent TFPI-regulating protein
chr11_+_33563821 0.01 ENST00000321505.4
ENST00000265654.5
ENST00000389726.3
KIAA1549L
KIAA1549-like
chr11_+_35211511 0.01 ENST00000524922.1
CD44
CD44 molecule (Indian blood group)
chr15_+_68117844 0.01 ENST00000554054.1
SKOR1
SKI family transcriptional corepressor 1
chr15_-_26874230 0.01 ENST00000400188.3
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr6_+_27806319 0.01 ENST00000606613.1
ENST00000396980.3
HIST1H2BN
histone cluster 1, H2bn
chr14_+_91581011 0.01 ENST00000523894.1
ENST00000522322.1
ENST00000523771.1
C14orf159
chromosome 14 open reading frame 159
chr11_-_107729504 0.01 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr17_+_36452989 0.00 ENST00000312513.5
ENST00000582535.1
MRPL45
mitochondrial ribosomal protein L45
chr9_+_114287433 0.00 ENST00000358151.4
ENST00000355824.3
ENST00000374374.3
ENST00000309235.5
ZNF483
zinc finger protein 483
chr2_-_71062938 0.00 ENST00000410009.3
CD207
CD207 molecule, langerin
chr9_+_100069933 0.00 ENST00000529487.1
CCDC180
coiled-coil domain containing 180
chr4_-_38666430 0.00 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr19_-_46148820 0.00 ENST00000587152.1
EML2
echinoderm microtubule associated protein like 2
chr4_-_177116772 0.00 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr10_-_105437909 0.00 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A

Network of associatons between targets according to the STRING database.

First level regulatory network of SMAD3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 1.0 GO:0090131 mesenchyme migration(GO:0090131)
0.1 0.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.6 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.2 GO:0061010 negative regulation of transcription by transcription factor localization(GO:0010621) gall bladder development(GO:0061010)
0.1 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.0 0.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:0055048 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.3 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.2 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) pyroptosis(GO:0070269)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.0 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.0 0.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.0 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.2 GO:0001534 radial spoke(GO:0001534)
0.0 0.3 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.2 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0032302 MutSbeta complex(GO:0032302)
0.0 0.2 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.4 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.2 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.0 0.2 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:0071553 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.3 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes