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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for SIX1_SIX3_SIX2

Z-value: 1.07

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Transcription factors associated with SIX1_SIX3_SIX2

Gene Symbol Gene ID Gene Info
ENSG00000126778.7 SIX homeobox 1
ENSG00000138083.3 SIX homeobox 3
ENSG00000170577.7 SIX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SIX1hg19_v2_chr14_-_61124977_61125037-0.742.6e-01Click!
SIX3hg19_v2_chr2_+_45168875_45168916-0.188.2e-01Click!

Activity profile of SIX1_SIX3_SIX2 motif

Sorted Z-values of SIX1_SIX3_SIX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_241695424 1.40 ENST00000366558.3
ENST00000366559.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr10_-_33405600 1.37 ENST00000414308.1
RP11-342D11.3
chr1_+_241695670 1.33 ENST00000366557.4
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr15_-_31521567 1.10 ENST00000560812.1
ENST00000559853.1
ENST00000558109.1
RP11-16E12.2
chr13_-_46679144 0.97 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr5_-_159846066 0.84 ENST00000519349.1
ENST00000520664.1
SLU7 splicing factor homolog (S. cerevisiae)
chr13_-_46679185 0.81 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr16_-_28550320 0.76 ENST00000395641.2
nuclear protein, transcriptional regulator, 1
chr7_+_139025875 0.65 ENST00000297534.6
chromosome 7 open reading frame 55
chr6_-_136847099 0.64 ENST00000438100.2
microtubule-associated protein 7
chr6_-_136847610 0.63 ENST00000454590.1
ENST00000432797.2
microtubule-associated protein 7
chr17_+_4675175 0.63 ENST00000270560.3
transmembrane 4 L six family member 5
chr16_+_22517166 0.62 ENST00000356156.3
nuclear pore complex interacting protein family, member B5
chr9_-_34662651 0.61 ENST00000259631.4
chemokine (C-C motif) ligand 27
chr16_-_28550348 0.60 ENST00000324873.6
nuclear protein, transcriptional regulator, 1
chr15_+_75491203 0.59 ENST00000562637.1
chromosome 15 open reading frame 39
chr3_+_149191723 0.57 ENST00000305354.4
transmembrane 4 L six family member 4
chr4_-_140477928 0.57 ENST00000274031.3
SET domain containing (lysine methyltransferase) 7
chr9_+_67977438 0.55 ENST00000456982.1
Protein LOC644249
chr2_-_150444300 0.54 ENST00000303319.5
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr19_+_45445524 0.51 ENST00000591600.1
apolipoprotein C-IV
chr10_-_134331695 0.49 ENST00000455414.1
RP11-432J24.5
chr12_+_147052 0.48 ENST00000594563.1
Uncharacterized protein
chr1_+_64014588 0.46 ENST00000371086.2
ENST00000340052.3
deleted in lymphocytic leukemia 2-like
chr3_+_149192475 0.46 ENST00000465758.1
transmembrane 4 L six family member 4
chr1_+_207277632 0.44 ENST00000421786.1
complement component 4 binding protein, alpha
chr4_+_89300158 0.43 ENST00000502870.1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr16_+_19098178 0.43 ENST00000568032.1
RP11-626G11.4
chr4_-_140477910 0.42 ENST00000404104.3
SET domain containing (lysine methyltransferase) 7
chr1_+_214776516 0.40 ENST00000366955.3
centromere protein F, 350/400kDa
chr12_-_10826612 0.39 ENST00000535345.1
ENST00000542562.1
serine/threonine/tyrosine kinase 1
chr15_+_59279851 0.39 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
ring finger protein 111
chr1_-_109618566 0.38 ENST00000338366.5
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr1_-_207119738 0.38 ENST00000356495.4
polymeric immunoglobulin receptor
chr8_-_95229531 0.36 ENST00000450165.2
cadherin 17, LI cadherin (liver-intestine)
chr17_-_7080883 0.36 ENST00000570576.1
asialoglycoprotein receptor 1
chr3_-_149095652 0.36 ENST00000305366.3
transmembrane 4 L six family member 1
chr4_-_467892 0.35 ENST00000506646.1
ENST00000505900.1
zinc finger protein 721
chr11_-_8892900 0.34 ENST00000526155.1
ENST00000524757.1
ENST00000527392.1
ENST00000534665.1
ENST00000525169.1
ENST00000527516.1
ENST00000533471.1
suppression of tumorigenicity 5
chr14_-_74296806 0.34 ENST00000555539.1
RP5-1021I20.2
chr4_+_155484155 0.33 ENST00000509493.1
fibrinogen beta chain
chr7_-_48068643 0.33 ENST00000453192.2
Sad1 and UNC84 domain containing 3
chr2_-_150444116 0.33 ENST00000428879.1
ENST00000422782.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr6_-_138428613 0.33 ENST00000421351.3
PERP, TP53 apoptosis effector
chr16_+_29690358 0.31 ENST00000395384.4
ENST00000562473.1
quinolinate phosphoribosyltransferase
chr10_-_38265517 0.31 ENST00000302609.7
zinc finger protein 25
chr20_-_55100981 0.30 ENST00000243913.4
glucosaminyl (N-acetyl) transferase family member 7
chr4_+_2794750 0.29 ENST00000452765.2
ENST00000389838.2
SH3-domain binding protein 2
chr4_+_159131346 0.29 ENST00000508243.1
ENST00000296529.6
transmembrane protein 144
chr1_+_53793885 0.28 ENST00000445039.2
RP4-784A16.5
chr2_+_161993465 0.28 ENST00000457476.1
TRAF family member-associated NFKB activator
chr14_+_54863667 0.28 ENST00000335183.6
cyclin-dependent kinase inhibitor 3
chr1_+_150245099 0.28 ENST00000369099.3
chromosome 1 open reading frame 54
chr14_+_54863682 0.27 ENST00000543789.2
ENST00000442975.2
ENST00000458126.2
ENST00000556102.2
cyclin-dependent kinase inhibitor 3
chr1_+_93913665 0.27 ENST00000271234.7
ENST00000370256.4
ENST00000260506.8
formin binding protein 1-like
chr11_+_327171 0.27 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr12_-_112614506 0.27 ENST00000548588.2
HECT domain containing E3 ubiquitin protein ligase 4
chr2_+_183989157 0.27 ENST00000541912.1
nucleoporin 35kDa
chr3_+_11267691 0.26 ENST00000413416.1
histamine receptor H1
chr10_-_103603523 0.26 ENST00000370046.1
Kv channel interacting protein 2
chr12_-_53594227 0.26 ENST00000550743.2
integrin, beta 7
chr3_+_184529929 0.25 ENST00000287546.4
ENST00000437079.3
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr8_+_19536083 0.25 ENST00000519803.1
RP11-1105O14.1
chr11_-_2924720 0.24 ENST00000455942.2
solute carrier family 22 (organic cation transporter), member 18 antisense
chr3_+_172034218 0.24 ENST00000366261.2
Uncharacterized protein
chr14_+_58711539 0.24 ENST00000216455.4
ENST00000412908.2
ENST00000557508.1
proteasome (prosome, macropain) subunit, alpha type, 3
chr11_+_85339623 0.23 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
transmembrane protein 126B
chr11_+_17298522 0.23 ENST00000529313.1
nucleobindin 2
chr11_+_71900572 0.23 ENST00000312293.4
folate receptor 1 (adult)
chr4_-_14889791 0.23 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
long intergenic non-protein coding RNA 504
chr19_+_11750566 0.23 ENST00000344893.3
zinc finger protein 833, pseudogene
chr1_-_44818599 0.22 ENST00000537474.1
ERI1 exoribonuclease family member 3
chr1_-_169337176 0.22 ENST00000472647.1
ENST00000367811.3
NME/NM23 family member 7
chr19_+_11457232 0.22 ENST00000587531.1
coiled-coil domain containing 159
chr9_-_113018746 0.22 ENST00000374515.5
thioredoxin
chr6_+_96969672 0.22 ENST00000369278.4
UFM1-specific ligase 1
chr22_+_21321531 0.21 ENST00000405089.1
ENST00000335375.5
apoptosis-inducing factor, mitochondrion-associated, 3
chr1_+_150245177 0.21 ENST00000369098.3
chromosome 1 open reading frame 54
chr14_+_91709103 0.20 ENST00000553725.1
HCG1816139; Uncharacterized protein
chr15_-_100258029 0.20 ENST00000378904.2
DKFZP779J2370
chr2_-_105953912 0.20 ENST00000610036.1
RP11-332H14.2
chr12_+_16500037 0.20 ENST00000536371.1
ENST00000010404.2
microsomal glutathione S-transferase 1
chr2_-_128615681 0.20 ENST00000409955.1
ENST00000272645.4
polymerase (RNA) II (DNA directed) polypeptide D
chr14_-_94759361 0.20 ENST00000393096.1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr1_+_215740709 0.20 ENST00000259154.4
potassium channel tetramerization domain containing 3
chr2_-_220034745 0.20 ENST00000455516.2
ENST00000396775.3
ENST00000295738.7
solute carrier family 23, member 3
chrX_+_75392771 0.20 ENST00000373358.3
ENST00000373357.3
polysaccharide biosynthesis domain containing 1
chr7_-_141541221 0.20 ENST00000350549.3
ENST00000438520.1
protease, serine, 37
chr2_-_107502456 0.20 ENST00000419159.2
ST6 beta-galactosamide alpha-2,6-sialyltranferase 2
chr7_+_90012986 0.19 ENST00000416322.1
claudin 12
chr11_-_118134997 0.19 ENST00000278937.2
myelin protein zero-like 2
chr18_+_61575200 0.19 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr19_+_45445491 0.19 ENST00000592954.1
ENST00000419266.2
ENST00000589057.1
apolipoprotein C-IV
APOC4-APOC2 readthrough (NMD candidate)
chr3_+_184529948 0.19 ENST00000436792.2
ENST00000446204.2
ENST00000422105.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr2_+_211421262 0.19 ENST00000233072.5
carbamoyl-phosphate synthase 1, mitochondrial
chr14_+_54863739 0.18 ENST00000541304.1
cyclin-dependent kinase inhibitor 3
chr11_+_102552041 0.18 ENST00000537079.1
Uncharacterized protein
chr5_-_145562147 0.18 ENST00000545646.1
ENST00000274562.9
ENST00000510191.1
ENST00000394434.2
leucyl-tRNA synthetase
chr4_-_156298028 0.18 ENST00000433024.1
ENST00000379248.2
microtubule-associated protein 9
chr14_-_24729251 0.18 ENST00000559136.1
transglutaminase 1
chr7_-_92219337 0.18 ENST00000456502.1
ENST00000427372.1
family with sequence similarity 133, member B
chr15_+_40331456 0.18 ENST00000504245.1
ENST00000560341.1
SRP14 antisense RNA1 (head to head)
chr8_-_124749609 0.18 ENST00000262219.6
ENST00000419625.1
annexin A13
chr1_-_179457805 0.18 ENST00000600581.1
Uncharacterized protein
chr12_-_89920030 0.18 ENST00000413530.1
ENST00000547474.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
POC1B-GALNT4 readthrough
chr17_-_33446735 0.18 ENST00000460118.2
ENST00000335858.7
RAD51 paralog D
chr17_+_73997796 0.17 ENST00000586261.1
cyclin-dependent kinase 3
chr6_-_31846744 0.17 ENST00000414427.1
ENST00000229729.6
ENST00000375562.4
solute carrier family 44, member 4
chr11_-_76155618 0.17 ENST00000530759.1
RP11-111M22.3
chr1_-_108743471 0.17 ENST00000569674.1
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr11_-_118135160 0.17 ENST00000438295.2
myelin protein zero-like 2
chr12_-_89919965 0.17 ENST00000548729.1
POC1B-GALNT4 readthrough
chr11_-_111794446 0.17 ENST00000527950.1
crystallin, alpha B
chr12_+_49717019 0.17 ENST00000549275.1
ENST00000551245.1
ENST00000380327.5
ENST00000548311.1
ENST00000550346.1
ENST00000550709.1
ENST00000549534.1
ENST00000257909.3
trophinin associated protein
chr11_+_34654011 0.17 ENST00000531794.1
ets homologous factor
chr1_+_207277590 0.17 ENST00000367070.3
complement component 4 binding protein, alpha
chr14_-_94759595 0.17 ENST00000261994.4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr11_+_100862811 0.16 ENST00000303130.2
transmembrane protein 133
chr12_-_49523896 0.16 ENST00000549870.1
tubulin, alpha 1b
chr4_+_119199904 0.16 ENST00000602483.1
ENST00000602819.1
small nucleolar RNA host gene 8 (non-protein coding)
chr3_+_42850959 0.16 ENST00000442925.1
ENST00000422265.1
ENST00000497921.1
ENST00000426937.1
atypical chemokine receptor 2
KRAB box domain containing 1
chr19_+_42055879 0.15 ENST00000407170.2
ENST00000601116.1
ENST00000595395.1
carcinoembryonic antigen-related cell adhesion molecule 21
AC006129.2
chrX_-_154060946 0.15 ENST00000369529.1
small integral membrane protein 9
chr5_-_133304473 0.15 ENST00000231512.3
chromosome 5 open reading frame 15
chr1_+_198189921 0.15 ENST00000391974.3
NIMA-related kinase 7
chr17_-_45056606 0.15 ENST00000322329.3
reprimo-like
chr6_+_147830362 0.15 ENST00000566741.1
sterile alpha motif domain containing 5
chr9_-_117568365 0.15 ENST00000374045.4
tumor necrosis factor (ligand) superfamily, member 15
chr3_-_129147432 0.15 ENST00000503957.1
ENST00000505956.1
ENST00000326085.3
EF-hand calcium binding domain 12
chr12_-_53901266 0.14 ENST00000609999.1
ENST00000267017.3
neuropeptide FF-amide peptide precursor
chr7_-_92219698 0.14 ENST00000438306.1
ENST00000445716.1
family with sequence similarity 133, member B
chr9_-_27005686 0.14 ENST00000380055.5
leucine rich repeat containing 19
chr2_-_55496344 0.14 ENST00000403721.1
ENST00000263629.4
mitochondrial translational initiation factor 2
chr8_+_76452097 0.14 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr4_-_156297919 0.14 ENST00000450097.1
microtubule-associated protein 9
chr4_+_159131596 0.14 ENST00000512481.1
transmembrane protein 144
chr2_-_18770812 0.13 ENST00000359846.2
ENST00000304081.4
ENST00000600945.1
ENST00000532967.1
ENST00000444297.2
5'-nucleotidase, cytosolic IB
NT5C1B-RDH14 readthrough
chr17_-_4938712 0.13 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chrX_+_101906294 0.13 ENST00000361600.5
ENST00000415986.1
ENST00000444152.1
ENST00000537097.1
G protein-coupled receptor associated sorting protein 1
chr10_+_48359344 0.13 ENST00000412534.1
ENST00000444585.1
zinc finger protein 488
chr19_-_3600549 0.13 ENST00000589966.1
thromboxane A2 receptor
chr16_+_16481306 0.13 ENST00000422673.2
nuclear pore complex interacting protein family, member A7
chr16_+_84402098 0.13 ENST00000262429.4
ENST00000416219.2
ATPase, Ca++ transporting, type 2C, member 2
chr7_+_141490017 0.13 ENST00000247883.4
taste receptor, type 2, member 5
chr15_+_75041184 0.13 ENST00000343932.4
cytochrome P450, family 1, subfamily A, polypeptide 2
chr7_+_95171457 0.13 ENST00000601424.1
Protein LOC100996577
chr6_-_32160622 0.12 ENST00000487761.1
ENST00000375040.3
G-protein signaling modulator 3
chr3_+_187957646 0.12 ENST00000457242.1
LIM domain containing preferred translocation partner in lipoma
chr7_+_16685756 0.12 ENST00000415365.1
ENST00000258761.3
ENST00000433922.2
ENST00000452975.2
ENST00000405202.1
basic leucine zipper and W2 domains 2
chr1_-_171711387 0.12 ENST00000236192.7
vesicle-associated membrane protein 4
chr10_+_104613980 0.12 ENST00000339834.5
chromosome 10 open reading frame 32
chr2_+_58134756 0.12 ENST00000435505.2
ENST00000417641.2
vaccinia related kinase 2
chr8_+_95835438 0.11 ENST00000521860.1
ENST00000519457.1
ENST00000519053.1
ENST00000523731.1
ENST00000447247.1
integrator complex subunit 8
chr9_+_6645887 0.11 ENST00000413145.1
RP11-390F4.6
chr16_+_22524379 0.11 ENST00000536620.1
nuclear pore complex interacting protein family, member B5
chr11_+_58874658 0.11 ENST00000411426.1
family with sequence similarity 111, member B
chr16_-_15736345 0.11 ENST00000549219.1
KIAA0430
chr5_+_70220768 0.11 ENST00000351205.4
ENST00000503079.2
ENST00000380707.4
ENST00000514951.1
ENST00000506163.1
survival of motor neuron 1, telomeric
chr1_+_17531614 0.11 ENST00000375471.4
peptidyl arginine deiminase, type I
chr5_-_141392538 0.11 ENST00000503794.1
ENST00000510194.1
ENST00000504424.1
ENST00000513454.1
ENST00000458112.2
ENST00000542860.1
ENST00000503229.1
ENST00000500692.2
ENST00000311337.6
ENST00000504139.1
ENST00000505689.1
glucosamine-6-phosphate deaminase 1
chr8_-_83589388 0.11 ENST00000522776.1
RP11-653B10.1
chr3_-_196669298 0.11 ENST00000411704.1
ENST00000452404.2
nuclear cap binding protein subunit 2, 20kDa
chr2_-_207630033 0.11 ENST00000449792.1
malate dehydrogenase 1B, NAD (soluble)
chr17_+_43213004 0.11 ENST00000586346.1
ENST00000398322.3
ENST00000592162.1
ENST00000376955.4
ENST00000321854.8
acyl-CoA binding domain containing 4
chr11_+_125365110 0.11 ENST00000527818.1
AP000708.1
chr8_+_35649365 0.11 ENST00000437887.1
Uncharacterized protein
chr11_-_82782952 0.11 ENST00000534141.1
RAB30, member RAS oncogene family
chr2_-_198299726 0.11 ENST00000409915.4
ENST00000487698.1
ENST00000414963.2
ENST00000335508.6
splicing factor 3b, subunit 1, 155kDa
chr4_-_156298087 0.11 ENST00000311277.4
microtubule-associated protein 9
chr2_+_161993412 0.10 ENST00000259075.2
ENST00000432002.1
TRAF family member-associated NFKB activator
chr2_-_187367356 0.10 ENST00000595956.1
AC018867.2
chr2_+_207630081 0.10 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FAST kinase domains 2
chr19_+_57999101 0.10 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
zinc finger protein 419
chr5_-_143550241 0.10 ENST00000522203.1
Yip1 domain family, member 5
chr17_+_75315654 0.10 ENST00000590595.1
septin 9
chrX_+_72064876 0.10 ENST00000373532.3
ENST00000333826.5
DMRT-like family C1B
chr8_-_29120604 0.10 ENST00000521515.1
kinesin family member 13B
chr17_-_8113542 0.10 ENST00000578549.1
ENST00000535053.1
ENST00000582368.1
aurora kinase B
chr7_+_151771377 0.10 ENST00000434507.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr12_-_111395610 0.10 ENST00000548329.1
ENST00000546852.1
RP1-46F2.3
chr19_+_56116771 0.10 ENST00000568956.1
zinc finger protein 865
chr19_-_43702231 0.10 ENST00000597374.1
ENST00000599371.1
pregnancy specific beta-1-glycoprotein 4
chr6_+_28048753 0.10 ENST00000377325.1
zinc finger protein 165
chr12_+_70574088 0.10 ENST00000552324.1
RP11-320P7.2
chr1_-_220220000 0.10 ENST00000366923.3
glutamyl-prolyl-tRNA synthetase
chr3_+_141144954 0.10 ENST00000441582.2
ENST00000321464.5
zinc finger and BTB domain containing 38
chr1_+_186265399 0.09 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
proteoglycan 4
chr8_-_66546373 0.09 ENST00000518908.1
ENST00000458464.2
ENST00000519352.1
armadillo repeat containing 1
chr7_-_123198284 0.09 ENST00000355749.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr7_+_139026057 0.09 ENST00000541515.3
LUC7-like 2 (S. cerevisiae)
chr4_-_156297949 0.09 ENST00000515654.1
microtubule-associated protein 9
chr10_-_43762329 0.09 ENST00000395810.1
RasGEF domain family, member 1A
chr1_-_156647189 0.09 ENST00000368223.3
nestin
chr20_+_34824355 0.09 ENST00000397286.3
ENST00000320849.4
ENST00000373932.3
AAR2 splicing factor homolog (S. cerevisiae)
chr16_+_29832634 0.09 ENST00000565164.1
ENST00000570234.1
major vault protein
chr13_-_47471155 0.09 ENST00000543956.1
ENST00000542664.1
5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
chr6_-_35656685 0.09 ENST00000539068.1
ENST00000540787.1
FK506 binding protein 5
chr4_-_83719884 0.09 ENST00000282709.4
ENST00000273908.4
stearoyl-CoA desaturase 5
chr1_-_12908578 0.09 ENST00000317869.6
heterogeneous nuclear ribonucleoprotein C-like 1
chr10_-_6622258 0.09 ENST00000263125.5
protein kinase C, theta

Network of associatons between targets according to the STRING database.

First level regulatory network of SIX1_SIX3_SIX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.4 2.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.3 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.3 GO:1903717 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 0.2 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 1.4 GO:2000194 regulation of female gonad development(GO:2000194)
0.1 0.8 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.4 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.4 GO:0008218 bioluminescence(GO:0008218)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.6 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.2 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.1 1.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 0.2 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.1 0.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.2 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.1 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.5 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.2 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.9 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.3 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.0 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:2000570 T-helper 2 cell activation(GO:0035712) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0010459 negative regulation of heart rate(GO:0010459)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.3 GO:0002934 desmosome organization(GO:0002934)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:1902159 regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:0006286 base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.4 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.6 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.7 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.4 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.2 0.8 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.4 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 0.4 GO:0032184 SUMO polymer binding(GO:0032184)
0.1 0.2 GO:0061714 folic acid receptor activity(GO:0061714)
0.1 0.3 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.2 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.1 1.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.4 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220) azole transporter activity(GO:0045118)
0.0 0.1 GO:0004766 spermidine synthase activity(GO:0004766)
0.0 0.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.0 0.2 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.0 0.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.0 GO:0015616 DNA translocase activity(GO:0015616)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome