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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for RUNX3_BCL11A

Z-value: 1.37

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Transcription factors associated with RUNX3_BCL11A

Gene Symbol Gene ID Gene Info
RUNX3
ENSG00000020633.14 RUNX family transcription factor 3
BCL11A
ENSG00000119866.16 BAF chromatin remodeling complex subunit BCL11A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BCL11Ahg19_v2_chr2_-_60780536_607805410.722.8e-01Click!
RUNX3hg19_v2_chr1_-_25291475_25291511-0.406.0e-01Click!

Activity profile of RUNX3_BCL11A motif

Sorted Z-values of RUNX3_BCL11A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_34417479 2.58 ENST00000225245.5
CCL3
chemokine (C-C motif) ligand 3
chr19_+_10197463 1.22 ENST00000590378.1
ENST00000397881.3
C19orf66
chromosome 19 open reading frame 66
chr3_+_136676707 0.99 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr15_-_60695071 0.95 ENST00000557904.1
ANXA2
annexin A2
chr15_+_67390920 0.84 ENST00000559092.1
ENST00000560175.1
SMAD3
SMAD family member 3
chr3_+_136676851 0.84 ENST00000309741.5
IL20RB
interleukin 20 receptor beta
chr12_-_56753858 0.83 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
STAT2
signal transducer and activator of transcription 2, 113kDa
chr4_+_71091786 0.72 ENST00000317987.5
FDCSP
follicular dendritic cell secreted protein
chr6_+_45296391 0.72 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr4_-_57976544 0.72 ENST00000295666.4
ENST00000537922.1
IGFBP7
insulin-like growth factor binding protein 7
chr3_+_51575596 0.71 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chr13_-_41111323 0.65 ENST00000595486.1
AL133318.1
Uncharacterized protein
chr1_+_66796401 0.65 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_+_164528437 0.63 ENST00000485769.1
PBX1
pre-B-cell leukemia homeobox 1
chr5_+_133451254 0.63 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr17_-_39183452 0.61 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr5_+_131409476 0.60 ENST00000296871.2
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr12_+_54694979 0.59 ENST00000552848.1
COPZ1
coatomer protein complex, subunit zeta 1
chr17_+_40119801 0.59 ENST00000585452.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_+_209859510 0.57 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr5_-_39270725 0.55 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr6_+_31950150 0.53 ENST00000537134.1
C4A
complement component 4A (Rodgers blood group)
chr20_+_43343886 0.51 ENST00000190983.4
WISP2
WNT1 inducible signaling pathway protein 2
chr4_+_89299994 0.50 ENST00000264346.7
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr4_+_89299885 0.49 ENST00000380265.5
ENST00000273960.3
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr3_+_98699880 0.47 ENST00000473756.1
LINC00973
long intergenic non-protein coding RNA 973
chr1_-_94147385 0.47 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr1_+_239882842 0.47 ENST00000448020.1
CHRM3
cholinergic receptor, muscarinic 3
chr9_-_32526299 0.47 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr1_+_66999799 0.46 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr20_+_43343517 0.45 ENST00000372865.4
WISP2
WNT1 inducible signaling pathway protein 2
chr6_-_31514516 0.45 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr17_-_19281203 0.44 ENST00000487415.2
B9D1
B9 protein domain 1
chr1_-_235098861 0.44 ENST00000458044.1
RP11-443B7.1
RP11-443B7.1
chr20_+_43343476 0.43 ENST00000372868.2
WISP2
WNT1 inducible signaling pathway protein 2
chr12_+_75874984 0.43 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chrX_-_19688475 0.42 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr22_+_31488433 0.41 ENST00000455608.1
SMTN
smoothelin
chr5_-_94417186 0.41 ENST00000312216.8
ENST00000512425.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_+_74741569 0.41 ENST00000233638.7
TLX2
T-cell leukemia homeobox 2
chr19_-_8567478 0.41 ENST00000255612.3
PRAM1
PML-RARA regulated adaptor molecule 1
chr3_+_113251143 0.41 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr2_+_97202480 0.40 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr6_+_15401075 0.39 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr17_-_1532106 0.39 ENST00000301335.5
ENST00000382147.4
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr16_-_69418553 0.39 ENST00000569542.2
TERF2
telomeric repeat binding factor 2
chr15_-_33180439 0.39 ENST00000559610.1
FMN1
formin 1
chr2_+_177001685 0.39 ENST00000432796.2
HOXD3
homeobox D3
chr17_+_9745786 0.38 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr17_-_34625719 0.37 ENST00000422211.2
ENST00000542124.1
CCL3L1
chemokine (C-C motif) ligand 3-like 1
chr14_-_105767598 0.36 ENST00000548421.1
BRF1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr7_+_76751926 0.36 ENST00000285871.4
ENST00000431197.1
CCDC146
coiled-coil domain containing 146
chr22_-_30642782 0.35 ENST00000249075.3
LIF
leukemia inhibitory factor
chr16_-_71918033 0.35 ENST00000425432.1
ENST00000313565.6
ENST00000568666.1
ENST00000562797.1
ENST00000564134.1
ZNF821
zinc finger protein 821
chr1_+_156308245 0.35 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC
TSSK6 activating co-chaperone
chr3_+_96533621 0.35 ENST00000542517.1
ENST00000506569.1
EPHA6
EPH receptor A6
chrX_-_106146547 0.34 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr11_-_128457446 0.34 ENST00000392668.4
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr20_+_43992094 0.32 ENST00000453003.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chrX_+_48542168 0.31 ENST00000376701.4
WAS
Wiskott-Aldrich syndrome
chr10_+_101419187 0.31 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr1_-_113161730 0.31 ENST00000544629.1
ENST00000543570.1
ENST00000360743.4
ENST00000490067.1
ENST00000343210.7
ENST00000369666.1
ST7L
suppression of tumorigenicity 7 like
chr1_-_145715565 0.31 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr19_-_8567505 0.30 ENST00000600262.1
PRAM1
PML-RARA regulated adaptor molecule 1
chr12_+_19358192 0.30 ENST00000538305.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr14_+_31959154 0.30 ENST00000550005.1
NUBPL
nucleotide binding protein-like
chr3_+_9944303 0.30 ENST00000421412.1
ENST00000295980.3
IL17RE
interleukin 17 receptor E
chr15_+_67418047 0.30 ENST00000540846.2
SMAD3
SMAD family member 3
chrX_+_68048803 0.29 ENST00000204961.4
EFNB1
ephrin-B1
chr2_+_202937972 0.29 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr15_+_63335899 0.29 ENST00000561266.1
TPM1
tropomyosin 1 (alpha)
chr2_+_27071292 0.29 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr2_+_97203082 0.29 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chrM_+_8366 0.28 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr22_-_30642728 0.28 ENST00000403987.3
LIF
leukemia inhibitory factor
chr17_-_41836153 0.28 ENST00000301691.2
SOST
sclerostin
chr1_-_179112173 0.27 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr17_-_1531635 0.27 ENST00000571650.1
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr16_-_69418649 0.27 ENST00000566257.1
TERF2
telomeric repeat binding factor 2
chr12_-_96793142 0.27 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr17_+_40118805 0.27 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr17_-_39674668 0.26 ENST00000393981.3
KRT15
keratin 15
chr17_+_73780852 0.26 ENST00000589666.1
UNK
unkempt family zinc finger
chr16_+_2802623 0.26 ENST00000576924.1
ENST00000575009.1
ENST00000576415.1
ENST00000571378.1
SRRM2
serine/arginine repetitive matrix 2
chr11_+_71276609 0.26 ENST00000398531.1
ENST00000376536.4
KRTAP5-10
keratin associated protein 5-10
chr5_+_159895275 0.26 ENST00000517927.1
MIR146A
microRNA 146a
chr1_-_153348067 0.25 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr5_-_94417314 0.25 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr2_-_127977654 0.25 ENST00000409327.1
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr1_-_12677714 0.25 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chrX_+_47441712 0.25 ENST00000218388.4
ENST00000377018.2
ENST00000456754.2
ENST00000377017.1
ENST00000441738.1
TIMP1
TIMP metallopeptidase inhibitor 1
chr14_+_23352374 0.25 ENST00000267396.4
ENST00000536884.1
REM2
RAS (RAD and GEM)-like GTP binding 2
chr1_+_155099927 0.25 ENST00000368407.3
EFNA1
ephrin-A1
chr4_-_185820602 0.25 ENST00000515864.1
ENST00000507183.1
RP11-701P16.4
long intergenic non-protein coding RNA 1093
chr2_+_228678550 0.25 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr2_+_12246664 0.24 ENST00000449986.1
AC096559.1
AC096559.1
chr20_+_31595406 0.24 ENST00000170150.3
BPIFB2
BPI fold containing family B, member 2
chr19_-_39322299 0.24 ENST00000601094.1
ENST00000595567.1
ENST00000602115.1
ENST00000601778.1
ENST00000597205.1
ENST00000595470.1
ECH1
enoyl CoA hydratase 1, peroxisomal
chr5_-_94417339 0.24 ENST00000429576.2
ENST00000508509.1
ENST00000510732.1
MCTP1
multiple C2 domains, transmembrane 1
chr4_-_54930790 0.24 ENST00000263921.3
CHIC2
cysteine-rich hydrophobic domain 2
chr4_+_89444961 0.23 ENST00000513325.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr14_-_23564320 0.23 ENST00000605057.1
ACIN1
apoptotic chromatin condensation inducer 1
chr6_+_131571535 0.23 ENST00000474850.2
AKAP7
A kinase (PRKA) anchor protein 7
chr10_-_375422 0.23 ENST00000434695.2
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr11_-_66103867 0.23 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr4_-_48116540 0.23 ENST00000506073.1
TXK
TXK tyrosine kinase
chr12_-_8693469 0.22 ENST00000545274.1
ENST00000446457.2
CLEC4E
C-type lectin domain family 4, member E
chr10_+_82219058 0.22 ENST00000372156.1
TSPAN14
tetraspanin 14
chr14_-_74462922 0.22 ENST00000553284.1
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr10_+_24738355 0.22 ENST00000307544.6
KIAA1217
KIAA1217
chr3_-_33686925 0.22 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr17_-_61777090 0.22 ENST00000578061.1
LIMD2
LIM domain containing 2
chr2_+_220325441 0.22 ENST00000396688.1
SPEG
SPEG complex locus
chr16_+_67312049 0.22 ENST00000565899.1
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr12_-_120805872 0.21 ENST00000546985.1
MSI1
musashi RNA-binding protein 1
chr2_+_182850551 0.21 ENST00000452904.1
ENST00000409137.3
ENST00000280295.3
PPP1R1C
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr12_-_4754339 0.21 ENST00000228850.1
AKAP3
A kinase (PRKA) anchor protein 3
chr11_+_114310164 0.20 ENST00000544196.1
ENST00000539754.1
ENST00000539275.1
REXO2
RNA exonuclease 2
chr6_+_159071015 0.20 ENST00000360448.3
SYTL3
synaptotagmin-like 3
chr17_-_69198295 0.20 ENST00000569074.1
CASC17
cancer susceptibility candidate 17 (non-protein coding)
chr17_-_7164410 0.20 ENST00000574070.1
CLDN7
claudin 7
chr1_+_155290677 0.20 ENST00000368354.3
ENST00000368352.5
RUSC1
RUN and SH3 domain containing 1
chr9_-_98079965 0.20 ENST00000289081.3
FANCC
Fanconi anemia, complementation group C
chr3_-_71179988 0.19 ENST00000491238.1
FOXP1
forkhead box P1
chr6_+_37787262 0.19 ENST00000287218.4
ZFAND3
zinc finger, AN1-type domain 3
chr15_+_58724184 0.19 ENST00000433326.2
LIPC
lipase, hepatic
chr1_+_198608146 0.19 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr5_-_65018834 0.19 ENST00000506816.1
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr7_+_96634850 0.19 ENST00000518156.2
DLX6
distal-less homeobox 6
chr20_+_36405665 0.19 ENST00000373469.1
CTNNBL1
catenin, beta like 1
chr12_-_54694758 0.18 ENST00000553070.1
NFE2
nuclear factor, erythroid 2
chr1_-_92951607 0.18 ENST00000427103.1
GFI1
growth factor independent 1 transcription repressor
chr17_-_34524157 0.18 ENST00000378354.4
ENST00000394484.1
CCL3L3
chemokine (C-C motif) ligand 3-like 3
chr16_+_20911174 0.18 ENST00000568663.1
LYRM1
LYR motif containing 1
chr1_-_179112189 0.18 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr1_+_89246647 0.18 ENST00000544045.1
PKN2
protein kinase N2
chr11_-_64885111 0.17 ENST00000528598.1
ENST00000310597.4
ZNHIT2
zinc finger, HIT-type containing 2
chr17_-_2169425 0.17 ENST00000570606.1
ENST00000354901.4
SMG6
SMG6 nonsense mediated mRNA decay factor
chr1_+_151171012 0.17 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chrX_-_49041242 0.17 ENST00000453382.1
ENST00000540849.1
ENST00000536904.1
ENST00000432913.1
PRICKLE3
prickle homolog 3 (Drosophila)
chr2_+_234826016 0.17 ENST00000324695.4
ENST00000433712.2
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr1_+_149553003 0.17 ENST00000369222.3
PPIAL4C
peptidylprolyl isomerase A (cyclophilin A)-like 4C
chr6_-_42418999 0.17 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr16_+_2802316 0.17 ENST00000301740.8
SRRM2
serine/arginine repetitive matrix 2
chr2_-_158300556 0.17 ENST00000264192.3
CYTIP
cytohesin 1 interacting protein
chrX_-_80377162 0.17 ENST00000430960.1
ENST00000447319.1
HMGN5
high mobility group nucleosome binding domain 5
chr11_+_114310102 0.17 ENST00000265881.5
REXO2
RNA exonuclease 2
chr14_+_35761580 0.16 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr4_-_10686475 0.16 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr6_-_152623231 0.16 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr22_+_19419425 0.16 ENST00000333130.3
MRPL40
mitochondrial ribosomal protein L40
chr2_+_30455016 0.16 ENST00000401506.1
ENST00000407930.2
LBH
limb bud and heart development
chr1_-_223536679 0.16 ENST00000608996.1
SUSD4
sushi domain containing 4
chr3_+_49977894 0.16 ENST00000433811.1
RBM6
RNA binding motif protein 6
chr9_-_130541017 0.16 ENST00000314830.8
SH2D3C
SH2 domain containing 3C
chr5_+_67535647 0.16 ENST00000520675.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_149889382 0.16 ENST00000369145.1
ENST00000369146.3
SV2A
synaptic vesicle glycoprotein 2A
chr11_+_35198243 0.16 ENST00000528455.1
CD44
CD44 molecule (Indian blood group)
chr16_+_58033450 0.16 ENST00000561743.1
USB1
U6 snRNA biogenesis 1
chr20_-_45035223 0.16 ENST00000450812.1
ENST00000290246.6
ENST00000439931.2
ENST00000396391.1
ELMO2
engulfment and cell motility 2
chr2_+_169659121 0.16 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN
nitric oxide synthase trafficking
chr5_-_39203093 0.16 ENST00000515010.1
FYB
FYN binding protein
chr5_+_172386517 0.16 ENST00000519522.1
RPL26L1
ribosomal protein L26-like 1
chr6_-_112081113 0.16 ENST00000517419.1
FYN
FYN oncogene related to SRC, FGR, YES
chr2_-_47382442 0.16 ENST00000445927.2
C2orf61
chromosome 2 open reading frame 61
chr1_+_156308403 0.15 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC
TSSK6 activating co-chaperone
chrX_-_77225135 0.15 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr8_+_27168988 0.15 ENST00000397501.1
ENST00000338238.4
ENST00000544172.1
PTK2B
protein tyrosine kinase 2 beta
chr11_-_62457371 0.15 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr15_-_78358465 0.15 ENST00000435468.1
TBC1D2B
TBC1 domain family, member 2B
chr2_-_4703793 0.15 ENST00000421212.1
ENST00000412134.1
AC022311.1
AC022311.1
chr20_-_45035198 0.15 ENST00000372176.1
ELMO2
engulfment and cell motility 2
chr6_+_143771934 0.15 ENST00000367592.1
PEX3
peroxisomal biogenesis factor 3
chr10_+_115511434 0.15 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr18_-_35145593 0.15 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
CELF4
CUGBP, Elav-like family member 4
chr17_+_38673270 0.15 ENST00000578280.1
RP5-1028K7.2
RP5-1028K7.2
chr2_+_74757050 0.15 ENST00000352222.3
ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr14_+_23563952 0.15 ENST00000319074.4
C14orf119
chromosome 14 open reading frame 119
chr11_+_36397528 0.15 ENST00000311599.5
ENST00000378867.3
PRR5L
proline rich 5 like
chr3_+_49977523 0.14 ENST00000422955.1
RBM6
RNA binding motif protein 6
chr3_-_71179699 0.14 ENST00000497355.1
FOXP1
forkhead box P1
chr1_-_25291475 0.14 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr6_+_144904334 0.14 ENST00000367526.4
UTRN
utrophin
chr17_-_4545170 0.14 ENST00000576394.1
ENST00000574640.1
ALOX15
arachidonate 15-lipoxygenase
chr13_-_46756351 0.14 ENST00000323076.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_-_8693539 0.14 ENST00000299663.3
CLEC4E
C-type lectin domain family 4, member E
chr11_+_1092184 0.14 ENST00000361558.6
MUC2
mucin 2, oligomeric mucus/gel-forming
chr11_+_60739140 0.14 ENST00000313421.7
CD6
CD6 molecule
chr16_+_69221028 0.14 ENST00000336278.4
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr10_+_25463951 0.14 ENST00000376351.3
GPR158
G protein-coupled receptor 158
chr6_-_30043539 0.14 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr1_-_40157345 0.13 ENST00000372844.3
HPCAL4
hippocalcin like 4
chr9_-_16253112 0.13 ENST00000380683.1
C9orf92
chromosome 9 open reading frame 92
chr1_+_156211753 0.13 ENST00000368272.4
BGLAP
bone gamma-carboxyglutamate (gla) protein
chr1_+_26872324 0.13 ENST00000531382.1
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr11_+_1892102 0.13 ENST00000417766.1
LSP1
lymphocyte-specific protein 1
chr1_+_202385953 0.13 ENST00000466968.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr2_+_153191706 0.13 ENST00000288670.9
FMNL2
formin-like 2
chr8_-_112248400 0.13 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chr1_-_184006611 0.13 ENST00000546159.1
COLGALT2
collagen beta(1-O)galactosyltransferase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX3_BCL11A

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.4 2.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 1.0 GO:0052418 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.2 0.6 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 0.7 GO:1903770 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.2 1.1 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.6 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.5 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.6 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 0.7 GO:0051414 response to cortisol(GO:0051414)
0.1 0.3 GO:0044725 chromatin reprogramming in the zygote(GO:0044725) DNA demethylation of male pronucleus(GO:0044727)
0.1 0.3 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.2 GO:0045362 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.3 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.1 0.3 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.1 0.5 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.1 0.8 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.2 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.1 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.1 0.2 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.1 0.1 GO:1904204 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.2 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.3 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.3 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.1 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.3 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.6 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0006939 smooth muscle contraction(GO:0006939)
0.0 0.2 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.7 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.3 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.1 GO:0070377 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.3 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.2 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.0 0.2 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:2000864 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384) tRNA transcription(GO:0009304)
0.0 0.1 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.0 0.1 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.1 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.1 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.0 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.2 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0002725 tolerance induction dependent upon immune response(GO:0002461) positive regulation of T cell anergy(GO:0002669) negative regulation of T cell cytokine production(GO:0002725) positive regulation of lymphocyte anergy(GO:0002913) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.3 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.3 GO:0061458 reproductive system development(GO:0061458)
0.0 0.8 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.0 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.1 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.2 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.4 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0007566 embryo implantation(GO:0007566)
0.0 0.1 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.5 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0043587 tongue morphogenesis(GO:0043587)
0.0 0.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.5 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.0 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.4 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.7 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.5 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.4 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 0.2 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.2 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.6 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698) CCR1 chemokine receptor binding(GO:0031726)
0.3 1.9 GO:0042015 interleukin-20 binding(GO:0042015)
0.2 0.9 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 0.6 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 1.1 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.4 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.1 0.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.3 GO:0005502 11-cis retinal binding(GO:0005502)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.5 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.6 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.8 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 2.0 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0015254 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0050473 hepoxilin-epoxide hydrolase activity(GO:0047977) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811)
0.0 0.3 GO:0042835 BRE binding(GO:0042835)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.1 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.0 0.8 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0051018 protein kinase A binding(GO:0051018)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.2 GO:0046935 insulin binding(GO:0043559) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.3 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 2.5 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID FGF PATHWAY FGF signaling pathway
0.0 0.9 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane