ISMARA results: RHOXF1

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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for RHOXF1

Z-value: 1.65

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Transcription factors associated with RHOXF1

Gene Symbol	Gene ID	Gene Info
RHOXF1 Ensembl NCBI GeneCards UniProt	ENSG00000101883.4	Rhox homeobox family member 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
RHOXF1	hg19_v2_chrX_-_119249819_119249847	-0.72	2.8e-01	Click!

Activity profile of RHOXF1 motif

Sorted Z-values of RHOXF1 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_121476959 Show fit	1.64	ENST00000339275.5	OASL Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase-like
chr12_+_113354341 Show fit	1.32	ENST00000553152.1	OAS1 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr6_-_32820529 Show fit	1.24	ENST00000425148.2	TAP1 Ensembl NCBI GeneCards UniProt Show fit	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_+_57308979 Show fit	1.16	ENST00000457912.1	SMTNL1 Ensembl NCBI GeneCards UniProt Show fit	smoothelin-like 1
chr12_+_113344811 Show fit	1.10	ENST00000551241.1 ENST00000553185.1 ENST00000550689.1	OAS1 Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_-_231090344 Show fit	1.06	ENST00000540870.1 ENST00000416610.1	SP110 Ensembl NCBI GeneCards UniProt Show fit	SP110 nuclear body protein
chr7_-_139763521 Show fit	0.98	ENST00000263549.3	PARP12 Ensembl NCBI GeneCards UniProt Show fit	poly (ADP-ribose) polymerase family, member 12
chr12_-_121476750 Show fit	0.97	ENST00000543677.1	OASL Ensembl NCBI GeneCards UniProt Show fit	2'-5'-oligoadenylate synthetase-like
chr11_-_33913708 Show fit	0.96	ENST00000257818.2	LMO2 Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 2 (rhombotin-like 1)
chr6_+_47666275 Show fit	0.94	ENST00000327753.3 ENST00000283303.2	GPR115 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 115

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of RHOXF1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	6.7	GO:0045071	negative regulation of viral genome replication(GO:0045071)
0.0	2.2	GO:0003254	regulation of membrane depolarization(GO:0003254)
0.4	1.7	GO:0046967	cytosol to ER transport(GO:0046967)
0.1	1.7	GO:0071294	cellular response to zinc ion(GO:0071294)
0.5	1.4	GO:0030187	melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1	1.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	1.3	GO:0070206	protein trimerization(GO:0070206)
0.2	1.2	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.2	1.2	GO:0061143	alveolar primary septum development(GO:0061143)
0.2	1.2	GO:1902164	mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)

Showing 1 to 10 of 301 entries

Gene overrepresentation in cellular_component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.1	GO:0001750	photoreceptor outer segment(GO:0001750)
0.2	1.7	GO:0042825	TAP complex(GO:0042825)
0.0	1.6	GO:0031430	M band(GO:0031430)
0.0	1.6	GO:0015030	Cajal body(GO:0015030)
0.1	1.2	GO:0097227	sperm annulus(GO:0097227)
0.0	1.1	GO:0045095	keratin filament(GO:0045095)
0.0	1.1	GO:0035577	azurophil granule membrane(GO:0035577)
0.1	1.0	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1	1.0	GO:0030678	mitochondrial ribonuclease P complex(GO:0030678)
0.1	0.9	GO:0030870	Mre11 complex(GO:0030870)

Showing 1 to 10 of 117 entries

Gene overrepresentation in molecular_function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.5	5.8	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2	1.7	GO:0046979	TAP2 binding(GO:0046979)
0.0	1.6	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	1.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.2	1.3	GO:0008172	S-methyltransferase activity(GO:0008172)
0.0	1.3	GO:0005112	Notch binding(GO:0005112)
0.0	1.3	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.0	1.2	GO:0002039	p53 binding(GO:0002039)
0.1	1.1	GO:0008179	adenylate cyclase binding(GO:0008179)
0.1	1.1	GO:0004526	ribonuclease P activity(GO:0004526)

Showing 1 to 10 of 199 entries

Gene overrepresentation in C2:CP category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	2.8	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.0	2.6	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	1.4	PID NOTCH PATHWAY	Notch signaling pathway
0.0	1.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	1.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.9	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.9	PID MYC PATHWAY	C-MYC pathway
0.1	0.8	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events

Showing 1 to 10 of 20 entries

Gene overrepresentation in C2:CP:REACTOME category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	8.6	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	1.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	1.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	1.2	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0	1.1	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.0	0.9	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.9	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.8	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.8	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation

Showing 1 to 10 of 39 entries

Results for RHOXF1

Z-value: 1.65

Motif logo

Transcription factors associated with RHOXF1

Activity-expression correlation:

Activity profile of RHOXF1 motif

Sorted Z-values of RHOXF1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of RHOXF1

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: