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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for RFX7_RFX4_RFX1
Z-value: 1.54
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Transcription factors associated with RFX7_RFX4_RFX1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| RFX1 | hg19_v2_chr19_-_14117074_14117141 | 0.41 | 5.9e-01 | Click! |
| RFX7 | hg19_v2_chr15_-_56535464_56535521 | -0.24 | 7.6e-01 | Click! |
| RFX4 | hg19_v2_chr12_+_106976678_106976708 | -0.19 | 8.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_51014460 Show fit | 1.77 |
ENST00000595669.1
|
Josephin domain containing 2 |
|
| chr19_-_51014588 Show fit | 1.62 |
ENST00000598418.1
|
Josephin domain containing 2 |
|
| chr17_+_2264983 Show fit | 1.21 |
ENST00000574650.1
|
small G protein signaling modulator 2 |
|
| chr1_+_161068179 Show fit | 1.18 |
ENST00000368011.4
ENST00000392192.2 |
kelch domain containing 9 |
|
| chr19_+_38880695 Show fit | 1.07 |
ENST00000587947.1
ENST00000338502.4 |
sprouty-related, EVH1 domain containing 3 |
|
| chr9_-_135545380 Show fit | 1.04 |
ENST00000544003.1
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
|
| chr5_-_7851260 Show fit | 0.97 |
ENST00000509627.1
|
chromosome 5 open reading frame 49 |
|
| chr19_-_51014345 Show fit | 0.89 |
ENST00000391815.3
ENST00000594350.1 ENST00000601423.1 |
Josephin domain containing 2 |
|
| chr2_+_54558004 Show fit | 0.85 |
ENST00000405749.1
ENST00000398634.2 ENST00000447328.1 |
chromosome 2 open reading frame 73 |
|
| chr17_+_48585794 Show fit | 0.76 |
ENST00000576179.1
ENST00000419930.1 |
MYCBP associated protein |
Network of associatons between targets according to the STRING database.
First level regulatory network of RFX7_RFX4_RFX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.2 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.0 | 1.0 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.0 | 0.8 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 0.7 | GO:1900242 | regulation of synaptic vesicle endocytosis(GO:1900242) |
| 0.2 | 0.6 | GO:0051562 | negative regulation of mitochondrial calcium ion concentration(GO:0051562) |
| 0.1 | 0.6 | GO:1903615 | regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615) |
| 0.0 | 0.5 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.0 | 0.5 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.5 | GO:0002021 | response to dietary excess(GO:0002021) |
| 0.1 | 0.4 | GO:0098904 | regulation of AV node cell action potential(GO:0098904) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.3 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 1.1 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.5 | GO:0031045 | dense core granule(GO:0031045) |
| 0.0 | 0.5 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.4 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.0 | 0.4 | GO:0034464 | BBSome(GO:0034464) |
| 0.0 | 0.3 | GO:0000125 | PCAF complex(GO:0000125) |
| 0.0 | 0.3 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.0 | 0.3 | GO:0002080 | acrosomal membrane(GO:0002080) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.6 | GO:0004843 | thiol-dependent ubiquitin-specific protease activity(GO:0004843) |
| 0.0 | 1.0 | GO:0031005 | filamin binding(GO:0031005) |
| 0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.0 | 0.5 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.1 | 0.4 | GO:0031812 | G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.0 | 0.4 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.0 | 0.4 | GO:0071253 | connexin binding(GO:0071253) |
| 0.0 | 0.4 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.0 | 0.4 | GO:0045503 | dynein light chain binding(GO:0045503) |
| 0.1 | 0.3 | GO:0052857 | NADHX epimerase activity(GO:0052856) NADPHX epimerase activity(GO:0052857) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.4 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.0 | 0.3 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |