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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for RELA

Z-value: 3.04

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Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
RELA
ENSG00000173039.14 RELA proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELAhg19_v2_chr11_-_65429891_654299150.821.8e-01Click!

Activity profile of RELA motif

Sorted Z-values of RELA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr20_-_62203808 4.38 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr6_+_138188351 4.37 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_-_191885686 4.28 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr9_-_21077939 3.78 ENST00000380232.2
IFNB1
interferon, beta 1, fibroblast
chr14_-_35873856 3.56 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr17_-_34207295 3.26 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr6_+_29691056 3.19 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr19_+_39759154 3.18 ENST00000331982.5
IFNL2
interferon, lambda 2
chr6_+_138188551 3.10 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_29691198 3.02 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr6_+_138188378 2.94 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_-_163175133 2.75 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr10_+_104154229 2.64 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_+_45504688 2.62 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr11_+_102188272 2.59 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr5_-_150460914 2.56 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr19_-_39735646 2.27 ENST00000413851.2
IFNL3
interferon, lambda 3
chr7_+_22766766 2.26 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr4_-_74864386 2.15 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr1_+_6845384 2.03 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr17_+_40440481 1.97 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr7_-_93520259 1.93 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr5_-_150460539 1.91 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr7_-_93520191 1.87 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr5_-_150467221 1.85 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr19_+_4229495 1.83 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr4_-_76957214 1.75 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr7_+_143078379 1.75 ENST00000449630.1
ENST00000457235.1
ZYX
zyxin
chr11_+_102188224 1.74 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr14_+_103589789 1.67 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr10_+_99609996 1.66 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr4_-_185395191 1.54 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr3_-_156878482 1.52 ENST00000295925.4
CCNL1
cyclin L1
chr3_+_101546827 1.45 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr14_-_24616426 1.44 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr9_-_136344197 1.44 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr4_+_74735102 1.44 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr19_+_10381769 1.43 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr4_-_74964904 1.42 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr9_-_32526299 1.42 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr4_+_4861385 1.38 ENST00000382723.4
MSX1
msh homeobox 1
chr12_+_48499883 1.35 ENST00000546755.1
ENST00000549366.1
ENST00000552792.1
PFKM
phosphofructokinase, muscle
chr4_-_74904398 1.28 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr9_-_32526184 1.28 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr20_+_1115821 1.26 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr9_-_125667494 1.25 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
RC3H2
ring finger and CCCH-type domains 2
chr20_-_4795747 1.25 ENST00000379376.2
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr14_+_103243813 1.25 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr5_-_150466692 1.22 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr10_+_104155450 1.21 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr11_+_18287801 1.20 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr2_+_97202480 1.20 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr14_+_24616588 1.16 ENST00000324103.6
ENST00000559260.1
RNF31
ring finger protein 31
chr19_+_35940486 1.16 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr9_+_127054254 1.15 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr7_+_69064566 1.14 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr5_+_118604385 1.12 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr11_+_18287721 1.11 ENST00000356524.4
SAA1
serum amyloid A1
chr6_+_144471643 1.07 ENST00000367568.4
STX11
syntaxin 11
chr5_-_141257954 1.07 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr10_+_13142075 1.07 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr14_-_103589246 1.06 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr3_-_156878540 1.03 ENST00000461804.1
CCNL1
cyclin L1
chr12_-_132905789 1.00 ENST00000328957.8
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr5_-_158526756 1.00 ENST00000313708.6
ENST00000517373.1
EBF1
early B-cell factor 1
chr19_+_41725088 1.00 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr1_-_89738528 1.00 ENST00000343435.5
GBP5
guanylate binding protein 5
chr5_+_159895275 0.99 ENST00000517927.1
MIR146A
microRNA 146a
chr10_+_13141585 0.98 ENST00000378764.2
OPTN
optineurin
chr17_-_4852332 0.98 ENST00000572383.1
PFN1
profilin 1
chr19_-_4182530 0.97 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
SIRT6
sirtuin 6
chr1_-_36615065 0.97 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr2_+_228678550 0.96 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr3_+_111578131 0.96 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr17_-_61777090 0.95 ENST00000578061.1
LIMD2
LIM domain containing 2
chr12_+_11802753 0.95 ENST00000396373.4
ETV6
ets variant 6
chr16_+_67282853 0.93 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr4_+_74702214 0.93 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr2_+_201987200 0.92 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr19_-_46272462 0.91 ENST00000317578.6
SIX5
SIX homeobox 5
chr13_+_53602894 0.91 ENST00000219022.2
OLFM4
olfactomedin 4
chr6_-_30712313 0.90 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr10_+_13142225 0.90 ENST00000378747.3
OPTN
optineurin
chr20_-_45530365 0.90 ENST00000414085.1
RP11-323C15.2
RP11-323C15.2
chr10_+_22605374 0.89 ENST00000448361.1
COMMD3
COMM domain containing 3
chr2_+_97203082 0.89 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr10_+_75668916 0.89 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr15_+_44719996 0.88 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_-_209825674 0.87 ENST00000367030.3
ENST00000356082.4
LAMB3
laminin, beta 3
chr15_+_44719790 0.86 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr10_+_30723045 0.85 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr10_+_12391685 0.85 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr9_-_130693048 0.84 ENST00000388747.4
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr7_+_143078652 0.83 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr5_+_10564432 0.83 ENST00000296657.5
ANKRD33B
ankyrin repeat domain 33B
chr1_-_153935983 0.83 ENST00000537590.1
ENST00000356205.4
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr10_+_22605304 0.82 ENST00000475460.2
ENST00000602390.1
ENST00000489125.2
ENST00000456711.1
ENST00000444869.1
COMMD3-BMI1
COMMD3
COMMD3-BMI1 readthrough
COMM domain containing 3
chr15_+_57884086 0.81 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1
GRINL1A complex locus 1
chr5_-_149792295 0.81 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr1_-_1822495 0.80 ENST00000378609.4
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
chr16_-_66959429 0.80 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr1_-_153935938 0.80 ENST00000368621.1
ENST00000368623.3
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chrX_+_152907913 0.79 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr6_+_106534192 0.78 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr19_-_46272106 0.78 ENST00000560168.1
SIX5
SIX homeobox 5
chr12_+_78224667 0.77 ENST00000549464.1
NAV3
neuron navigator 3
chr19_+_41725140 0.77 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr10_-_7708918 0.76 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr12_+_48499252 0.75 ENST00000549003.1
ENST00000550924.1
PFKM
phosphofructokinase, muscle
chr17_+_40440094 0.75 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr5_+_14143728 0.74 ENST00000344204.4
ENST00000537187.1
TRIO
trio Rho guanine nucleotide exchange factor
chr7_+_143771275 0.74 ENST00000408898.2
OR2A25
olfactory receptor, family 2, subfamily A, member 25
chr15_+_57884117 0.73 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr12_-_76425368 0.73 ENST00000602540.1
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr12_+_7053228 0.72 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr4_+_185395947 0.72 ENST00000605834.1
RP11-326I11.3
RP11-326I11.3
chr3_-_111852061 0.71 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr4_+_103422471 0.70 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr11_+_10476851 0.70 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr19_-_4831701 0.69 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr14_-_69446034 0.69 ENST00000193403.6
ACTN1
actinin, alpha 1
chr21_+_34775698 0.68 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr1_+_151171012 0.68 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr5_-_58652788 0.67 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr14_+_75988768 0.67 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr7_+_120629653 0.66 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr5_-_178054014 0.65 ENST00000520957.1
CLK4
CDC-like kinase 4
chr1_-_94079648 0.65 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr2_+_202047596 0.65 ENST00000286186.6
ENST00000360132.3
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr4_-_185395672 0.64 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr4_+_41614720 0.64 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr12_+_7053172 0.63 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr21_+_34775181 0.63 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr9_-_125667618 0.63 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr7_-_24797032 0.63 ENST00000409970.1
ENST00000409775.3
DFNA5
deafness, autosomal dominant 5
chr6_-_24720226 0.62 ENST00000378102.3
C6orf62
chromosome 6 open reading frame 62
chr8_+_21899898 0.61 ENST00000518533.1
ENST00000359441.3
FGF17
fibroblast growth factor 17
chr4_-_140222358 0.61 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_+_6740888 0.61 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr2_+_234602305 0.60 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr19_-_54984354 0.59 ENST00000301200.2
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr5_-_54468974 0.58 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr9_+_127054217 0.58 ENST00000394199.2
ENST00000546191.1
NEK6
NIMA-related kinase 6
chr22_-_37640277 0.58 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr2_-_177502659 0.57 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr11_-_6633799 0.57 ENST00000299424.4
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr22_-_37640456 0.56 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr6_+_29910301 0.56 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr6_+_32121908 0.56 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr1_-_8000872 0.56 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr15_+_44719970 0.56 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr12_+_49761224 0.56 ENST00000553127.1
ENST00000321898.6
SPATS2
spermatogenesis associated, serine-rich 2
chr9_-_127952032 0.56 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C
protein phosphatase 6, catalytic subunit
chr20_+_18488528 0.55 ENST00000377465.1
SEC23B
Sec23 homolog B (S. cerevisiae)
chr21_+_34775772 0.54 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr15_+_27216530 0.54 ENST00000555083.1
GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr19_+_45251804 0.54 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr11_-_128392085 0.52 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1
v-ets avian erythroblastosis virus E26 oncogene homolog 1
chr14_+_24521202 0.52 ENST00000334420.7
ENST00000342740.5
LRRC16B
leucine rich repeat containing 16B
chr11_-_44331679 0.52 ENST00000329255.3
ALX4
ALX homeobox 4
chr13_+_108921977 0.52 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr1_+_6845497 0.52 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr12_-_48499591 0.52 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr19_-_4182497 0.51 ENST00000597896.1
SIRT6
sirtuin 6
chr22_-_20792089 0.51 ENST00000405555.3
ENST00000266214.5
SCARF2
scavenger receptor class F, member 2
chr20_+_18488137 0.51 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr9_+_82187487 0.51 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr9_+_82187630 0.50 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr19_+_42381173 0.50 ENST00000221972.3
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr12_-_62997214 0.49 ENST00000408887.2
C12orf61
chromosome 12 open reading frame 61
chr22_-_39151434 0.47 ENST00000439339.1
SUN2
Sad1 and UNC84 domain containing 2
chr3_+_197518100 0.47 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr1_-_32403903 0.47 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr19_+_40697514 0.46 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr18_+_3252265 0.46 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr15_-_66084621 0.45 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr14_-_69262916 0.45 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr3_-_111852128 0.45 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr11_+_66025274 0.44 ENST00000461611.1
KLC2
kinesin light chain 2
chr12_+_7052974 0.44 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr6_-_150039170 0.44 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr4_-_103749179 0.44 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr3_+_137717571 0.43 ENST00000343735.4
CLDN18
claudin 18
chr14_+_32798462 0.43 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr2_+_179059365 0.43 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr19_-_46145696 0.43 ENST00000588172.1
EML2
echinoderm microtubule associated protein like 2
chr11_-_46141338 0.43 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHF21A
PHD finger protein 21A
chr6_+_135502466 0.43 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr11_-_3862206 0.43 ENST00000351018.4
RHOG
ras homolog family member G
chr4_+_146560245 0.43 ENST00000541599.1
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr15_+_57884199 0.42 ENST00000587652.1
ENST00000380568.3
ENST00000380565.4
ENST00000380563.2
GCOM1
MYZAP
POLR2M
GRINL1A complex locus 1
myocardial zonula adherens protein
polymerase (RNA) II (DNA directed) polypeptide M
chr2_+_202047843 0.41 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr8_+_42128861 0.41 ENST00000518983.1
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr2_+_17721920 0.40 ENST00000295156.4
VSNL1
visinin-like 1
chr7_-_127032363 0.40 ENST00000393312.1
ZNF800
zinc finger protein 800
chr11_-_64570624 0.40 ENST00000439069.1
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr4_+_103422499 0.40 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_-_209824643 0.39 ENST00000391911.1
ENST00000415782.1
LAMB3
laminin, beta 3
chr1_+_182584314 0.39 ENST00000566297.1
RP11-317P15.4
RP11-317P15.4
chr3_+_57261859 0.39 ENST00000495803.1
ENST00000444459.1
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
1.5 7.5 GO:0052250 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
1.4 5.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
1.1 4.4 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
1.1 3.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
1.1 4.3 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.8 2.3 GO:2000366 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.7 3.6 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.7 6.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.6 3.8 GO:0002725 negative regulation of T cell cytokine production(GO:0002725)
0.5 2.7 GO:0000255 allantoin metabolic process(GO:0000255)
0.5 1.5 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.5 1.4 GO:0090427 activation of meiosis(GO:0090427)
0.4 1.8 GO:0036343 psychomotor behavior(GO:0036343)
0.4 4.3 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.4 1.7 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.4 2.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.4 1.2 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.4 9.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.4 1.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.4 2.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.3 1.0 GO:0072616 interleukin-18 secretion(GO:0072616)
0.3 1.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.3 1.8 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.3 0.6 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.3 0.8 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 0.8 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 1.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.2 1.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.2 0.9 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 1.9 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.2 1.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 0.8 GO:0098582 innate vocalization behavior(GO:0098582)
0.2 2.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 1.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 0.7 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.2 0.5 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.3 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.4 GO:1904899 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.4 GO:0051685 maintenance of ER location(GO:0051685)
0.1 3.2 GO:0002385 mucosal immune response(GO:0002385)
0.1 1.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 1.7 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.4 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.7 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.0 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.1 0.4 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.1 0.2 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.5 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.7 GO:0006196 AMP catabolic process(GO:0006196)
0.1 3.8 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.1 0.3 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.1 0.9 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.1 0.3 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.1 0.3 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.1 1.7 GO:0051601 exocyst localization(GO:0051601)
0.1 1.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.1 1.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 0.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 1.0 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.1 1.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.4 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.9 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.5 GO:0030578 PML body organization(GO:0030578)
0.1 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.1 0.2 GO:1903384 enzyme active site formation(GO:0018307) neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) detoxification of mercury ion(GO:0050787) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 0.3 GO:1902534 single-organism membrane invagination(GO:1902534)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.4 GO:0060527 embryonic hindgut morphogenesis(GO:0048619) prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1 0.5 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 1.8 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 1.8 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.4 GO:2001205 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 0.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 2.1 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.3 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 1.1 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.3 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.6 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 1.7 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.2 GO:0050976 sensory perception of touch(GO:0050975) detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.8 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 2.3 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.7 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 2.1 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0032782 bile acid secretion(GO:0032782)
0.0 1.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.6 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.1 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 1.4 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0002295 T-helper cell lineage commitment(GO:0002295) CD4-positive, alpha-beta T cell lineage commitment(GO:0043373)
0.0 0.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.7 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.5 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.2 GO:0060161 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 1.1 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.2 GO:0032415 regulation of sodium:proton antiporter activity(GO:0032415) positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 1.7 GO:0071357 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0 2.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 2.7 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:0001828 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:0051198 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:0044793 negative regulation by host of viral process(GO:0044793)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0046959 habituation(GO:0046959)
0.0 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.0 0.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 1.1 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.3 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.9 GO:0060113 inner ear receptor cell differentiation(GO:0060113)
0.0 1.8 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.6 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 0.2 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.7 6.8 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.6 6.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 1.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 1.5 GO:0031933 telomeric heterochromatin(GO:0031933)
0.3 2.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.4 GO:0008537 proteasome activator complex(GO:0008537)
0.2 1.2 GO:0071797 LUBAC complex(GO:0071797)
0.2 0.8 GO:0016938 kinesin I complex(GO:0016938)
0.1 2.7 GO:0097342 ripoptosome(GO:0097342)
0.1 1.3 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.3 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.1 0.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 1.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 1.8 GO:0033643 host cell part(GO:0033643)
0.1 1.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.3 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 1.1 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.6 GO:0000125 PCAF complex(GO:0000125)
0.1 0.2 GO:0035101 FACT complex(GO:0035101)
0.0 1.7 GO:0000145 exocyst(GO:0000145)
0.0 0.8 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 1.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 2.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.7 GO:0005916 fascia adherens(GO:0005916)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.7 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 2.1 GO:1904724 specific granule lumen(GO:0035580) tertiary granule lumen(GO:1904724)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.4 GO:0001772 immunological synapse(GO:0001772)
0.0 3.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 2.6 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0045180 basal cortex(GO:0045180)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.4 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 2.1 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 1.9 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.8 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 2.2 GO:0031674 I band(GO:0031674)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.2 GO:0046979 TAP2 binding(GO:0046979)
0.8 3.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.7 3.3 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.6 10.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.5 7.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.5 1.5 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.3 1.8 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.2 1.5 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.2 2.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.2 1.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.2 0.5 GO:0008384 IkappaB kinase activity(GO:0008384)
0.2 0.8 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.2 1.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 10.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 0.5 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 1.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.2 GO:0045159 myosin II binding(GO:0045159)
0.1 4.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 3.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 1.2 GO:0031996 thioesterase binding(GO:0031996)
0.1 0.7 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.4 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 0.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.1 GO:0046965 retinoid X receptor binding(GO:0046965)
0.1 1.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 1.4 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.9 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 2.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 5.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 1.0 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 2.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 1.3 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 1.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 5.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.0 4.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.9 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 1.2 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015) vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 1.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.7 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 2.9 GO:0005125 cytokine activity(GO:0005125)
0.0 0.6 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.3 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.2 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 1.8 GO:0000149 SNARE binding(GO:0000149)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.9 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 1.1 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.4 24.2 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.2 5.8 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 2.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.8 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.7 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.6 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.5 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 6.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 10.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.4 1.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3 10.9 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 6.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 15.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 11.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 3.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 1.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 4.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.9 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 2.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.4 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.7 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.0 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis