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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for RCOR1_MTA3
Z-value: 1.15
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Transcription factors associated with RCOR1_MTA3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MTA3 | hg19_v2_chr2_+_42721689_42721723 | 0.77 | 2.3e-01 | Click! |
| RCOR1 | hg19_v2_chr14_+_103058948_103059005 | -0.00 | 1.0e+00 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of RCOR1_MTA3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.4 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.1 | 2.9 | GO:0051383 | kinetochore organization(GO:0051383) |
| 0.0 | 2.9 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.1 | 2.6 | GO:0061641 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.1 | 2.4 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.0 | 2.3 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 2.0 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.1 | 1.9 | GO:1903830 | magnesium ion transmembrane transport(GO:1903830) |
| 0.0 | 1.9 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.0 | 1.7 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.3 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 3.9 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 3.1 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 3.1 | GO:0005798 | Golgi-associated vesicle(GO:0005798) |
| 0.0 | 2.7 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 2.5 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.0 | 2.3 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 2.1 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 2.0 | GO:0035869 | ciliary transition zone(GO:0035869) |
| 0.0 | 1.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.6 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 3.2 | GO:0042393 | histone binding(GO:0042393) |
| 0.3 | 2.5 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.1 | 2.1 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
| 0.1 | 1.9 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.0 | 1.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 1.8 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.0 | 1.8 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 1.7 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 1.7 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.3 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 4.6 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 4.2 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 3.0 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 2.8 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.0 | 2.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 2.5 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 2.5 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 2.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 2.0 | PID FANCONI PATHWAY | Fanconi anemia pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 8.8 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.0 | 3.7 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 2.6 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 2.4 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 2.4 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 2.2 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.1 | 2.1 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 2.0 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 1.9 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |