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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for RARB

Z-value: 1.26

Motif logo

Transcription factors associated with RARB

Gene Symbol Gene ID Gene Info
ENSG00000077092.14 retinoic acid receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RARBhg19_v2_chr3_+_25469724_254697730.982.3e-02Click!

Activity profile of RARB motif

Sorted Z-values of RARB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_100140331 1.93 ENST00000407820.2
ENST00000394897.1
ENST00000508558.1
ENST00000394899.2
alcohol dehydrogenase 6 (class V)
chr9_+_67977438 1.88 ENST00000456982.1
Protein LOC644249
chr7_-_98805129 1.35 ENST00000327442.6
karyopherin alpha 7 (importin alpha 8)
chr6_+_49431073 1.14 ENST00000335783.3
centromere protein Q
chr3_+_119316721 1.10 ENST00000488919.1
ENST00000495992.1
phospholipase A1 member A
chr22_-_37976082 1.02 ENST00000215886.4
lectin, galactoside-binding, soluble, 2
chr6_-_49430886 1.02 ENST00000274813.3
methylmalonyl CoA mutase
chr10_-_101825151 0.96 ENST00000441382.1
carboxypeptidase N, polypeptide 1
chr8_-_95274536 0.91 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr3_+_119316689 0.91 ENST00000273371.4
phospholipase A1 member A
chr15_-_31521567 0.89 ENST00000560812.1
ENST00000559853.1
ENST00000558109.1
RP11-16E12.2
chr17_-_2318731 0.88 ENST00000609667.1
Uncharacterized protein
chr19_+_29704142 0.86 ENST00000587859.1
ENST00000590607.1
CTB-32O4.2
chr22_+_39493207 0.82 ENST00000348946.4
ENST00000442487.3
ENST00000421988.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr19_-_58204128 0.80 ENST00000597520.1
Uncharacterized protein
chr15_+_29211570 0.79 ENST00000558804.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr2_+_217082311 0.77 ENST00000597904.1
RP11-566E18.3
chr17_-_41277317 0.75 ENST00000497488.1
ENST00000489037.1
ENST00000470026.1
ENST00000586385.1
ENST00000591534.1
ENST00000591849.1
breast cancer 1, early onset
chr8_+_74903580 0.67 ENST00000284818.2
ENST00000518893.1
lymphocyte antigen 96
chr19_-_9731872 0.65 ENST00000424629.1
ENST00000326044.5
ENST00000354661.4
ENST00000435550.1
ENST00000444611.1
ENST00000421525.1
zinc finger protein 561
chr17_-_41277370 0.65 ENST00000476777.1
ENST00000491747.2
ENST00000478531.1
ENST00000477152.1
ENST00000357654.3
ENST00000493795.1
ENST00000493919.1
breast cancer 1, early onset
chr18_+_657578 0.64 ENST00000323274.10
thymidylate synthetase
chr19_+_21106081 0.64 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr9_+_104296163 0.63 ENST00000374819.2
ENST00000479306.1
ring finger protein 20, E3 ubiquitin protein ligase
chrX_+_23682379 0.58 ENST00000379349.1
peroxiredoxin 4
chr12_-_112443830 0.57 ENST00000550037.1
ENST00000549425.1
transmembrane protein 116
chr1_+_35544968 0.56 ENST00000359858.4
ENST00000373330.1
zinc finger, MYM-type 1
chr1_+_53392901 0.56 ENST00000371514.3
ENST00000528311.1
ENST00000371509.4
ENST00000407246.2
ENST00000371513.5
sterol carrier protein 2
chr6_-_52859046 0.54 ENST00000457564.1
ENST00000541324.1
ENST00000370960.1
glutathione S-transferase alpha 4
chr4_+_56719782 0.53 ENST00000381295.2
ENST00000346134.7
ENST00000349598.6
exocyst complex component 1
chr1_-_109618566 0.53 ENST00000338366.5
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
chr13_+_73302047 0.52 ENST00000377814.2
ENST00000377815.3
ENST00000390667.5
bora, aurora kinase A activator
chr16_-_46649905 0.51 ENST00000569702.1
SHC SH2-domain binding protein 1
chr11_+_95523621 0.51 ENST00000325542.5
ENST00000325486.5
ENST00000544522.1
ENST00000541365.1
centrosomal protein 57kDa
chr4_+_2451700 0.51 ENST00000506607.1
Uncharacterized protein
chrY_-_23548246 0.50 ENST00000382764.1
chromosome Y open reading frame 17
chr1_+_28836561 0.49 ENST00000419074.1
regulator of chromosome condensation 1
chr5_+_27472371 0.48 ENST00000512067.1
ENST00000510165.1
ENST00000505775.1
ENST00000514844.1
ENST00000503107.1
long intergenic non-protein coding RNA 1021
chr12_+_20522179 0.46 ENST00000359062.3
phosphodiesterase 3A, cGMP-inhibited
chr10_-_27389320 0.46 ENST00000436985.2
ankyrin repeat domain 26
chr3_+_49297518 0.45 ENST00000440528.3
Uncharacterized protein
chr12_+_57810198 0.42 ENST00000598001.1
HCG1818482; Uncharacterized protein
chr12_+_57854274 0.42 ENST00000528432.1
GLI family zinc finger 1
chr19_+_38880695 0.42 ENST00000587947.1
ENST00000338502.4
sprouty-related, EVH1 domain containing 3
chrX_-_119709637 0.42 ENST00000404115.3
cullin 4B
chr11_-_798239 0.41 ENST00000531437.1
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr6_+_76311568 0.41 ENST00000370014.3
SUMO1/sentrin specific peptidase 6
chr1_-_150693318 0.40 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMA domain containing 1
chr15_-_54051831 0.40 ENST00000557913.1
ENST00000360509.5
WD repeat domain 72
chr1_-_53019059 0.39 ENST00000484723.2
ENST00000524582.1
zinc finger, CCHC domain containing 11
chr4_+_128802016 0.38 ENST00000270861.5
ENST00000515069.1
ENST00000513090.1
ENST00000507249.1
polo-like kinase 4
chrX_+_123095890 0.38 ENST00000435215.1
stromal antigen 2
chr1_-_86861660 0.38 ENST00000486215.1
outer dense fiber of sperm tails 2-like
chr3_-_195938256 0.37 ENST00000296326.3
zinc finger, DHHC-type containing 19
chr19_+_18485509 0.37 ENST00000597765.1
growth differentiation factor 15
chr4_+_124317940 0.36 ENST00000505319.1
ENST00000339241.1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr6_+_2988199 0.36 ENST00000450238.1
ENST00000445000.1
ENST00000426637.1
long intergenic non-protein coding RNA 1011
NAD(P)H dehydrogenase, quinone 2
chr1_+_52521797 0.36 ENST00000313334.8
basic transcription factor 3-like 4
chr10_-_33625154 0.35 ENST00000265371.4
neuropilin 1
chr2_-_3521518 0.35 ENST00000382093.5
acireductone dioxygenase 1
chr5_-_141392538 0.34 ENST00000503794.1
ENST00000510194.1
ENST00000504424.1
ENST00000513454.1
ENST00000458112.2
ENST00000542860.1
ENST00000503229.1
ENST00000500692.2
ENST00000311337.6
ENST00000504139.1
ENST00000505689.1
glucosamine-6-phosphate deaminase 1
chr7_-_5998714 0.34 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr11_-_796197 0.34 ENST00000530360.1
ENST00000528606.1
ENST00000320230.5
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr12_+_56075330 0.34 ENST00000394252.3
methyltransferase like 7B
chr2_-_175499294 0.33 ENST00000392547.2
WAS/WASL interacting protein family, member 1
chr1_-_110052302 0.33 ENST00000369864.4
ENST00000369862.1
adhesion molecule with Ig-like domain 1
chr4_-_171011323 0.33 ENST00000509167.1
ENST00000353187.2
ENST00000507375.1
ENST00000515480.1
aminoadipate aminotransferase
chr5_-_133968529 0.32 ENST00000402673.2
SAR1 homolog B (S. cerevisiae)
chr1_+_221051699 0.31 ENST00000366903.6
H2.0-like homeobox
chr1_-_52521831 0.31 ENST00000371626.4
thioredoxin domain containing 12 (endoplasmic reticulum)
chr5_+_140174429 0.29 ENST00000520672.2
ENST00000378132.1
ENST00000526136.1
protocadherin alpha 2
chr2_+_132287237 0.29 ENST00000467992.2
coiled-coil domain containing 74A
chr1_-_150693305 0.29 ENST00000368987.1
HORMA domain containing 1
chr6_+_76311736 0.29 ENST00000447266.2
SUMO1/sentrin specific peptidase 6
chr2_-_25194476 0.28 ENST00000534855.1
DnaJ (Hsp40) homolog, subfamily C, member 27
chr12_-_112443767 0.28 ENST00000550233.1
ENST00000546962.1
ENST00000550800.2
transmembrane protein 116
chr11_+_31531291 0.28 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
elongator acetyltransferase complex subunit 4
chr10_-_65028938 0.27 ENST00000402544.1
jumonji domain containing 1C
chr1_+_78245303 0.27 ENST00000370791.3
ENST00000443751.2
family with sequence similarity 73, member A
chr22_+_39493268 0.26 ENST00000401756.1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr11_-_506316 0.26 ENST00000532055.1
ENST00000531540.1
ribonuclease/angiogenin inhibitor 1
chr10_-_43762329 0.26 ENST00000395810.1
RasGEF domain family, member 1A
chr1_+_52521957 0.26 ENST00000472944.2
ENST00000484036.1
basic transcription factor 3-like 4
chr12_+_49658855 0.25 ENST00000549183.1
tubulin, alpha 1c
chr8_-_141774467 0.25 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr20_+_43990576 0.25 ENST00000372727.1
ENST00000414310.1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr19_+_49468558 0.24 ENST00000331825.6
ferritin, light polypeptide
chr18_-_21852143 0.24 ENST00000399443.3
oxysterol binding protein-like 1A
chr6_+_31638156 0.24 ENST00000409525.1
lymphocyte antigen 6 complex, locus G5B
chr10_-_27530997 0.23 ENST00000375901.1
ENST00000412279.1
ENST00000375905.4
acyl-CoA binding domain containing 5
chr4_-_69536346 0.23 ENST00000338206.5
UDP glucuronosyltransferase 2 family, polypeptide B15
chrX_+_123095860 0.23 ENST00000428941.1
stromal antigen 2
chr16_-_1275257 0.23 ENST00000234798.4
tryptase gamma 1
chr19_+_13228917 0.22 ENST00000586171.1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr16_+_2533020 0.22 ENST00000562105.1
TBC1 domain family, member 24
chr19_-_33360647 0.22 ENST00000590341.1
ENST00000587772.1
ENST00000023064.4
solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
chr19_+_5914213 0.22 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
calcyphosine
chr6_-_28367510 0.22 ENST00000361028.1
zinc finger and SCAN domain containing 12
chr10_-_65028817 0.21 ENST00000542921.1
jumonji domain containing 1C
chr9_-_104145795 0.21 ENST00000259407.2
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr4_-_7436671 0.21 ENST00000319098.4
prosaposin-like 1 (gene/pseudogene)
chr17_+_73997419 0.21 ENST00000425876.2
cyclin-dependent kinase 3
chrX_-_134429952 0.20 ENST00000370764.1
zinc finger protein 75D
chr6_+_88106840 0.20 ENST00000369570.4
chromosome 6 open reading frame 164
chr1_-_150979333 0.20 ENST00000312210.5
family with sequence similarity 63, member A
chr1_+_202792385 0.19 ENST00000549576.1
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr2_+_29117509 0.19 ENST00000407426.3
WD repeat domain 43
chr10_-_8095412 0.19 ENST00000458727.1
ENST00000355358.1
RP11-379F12.3
GATA3 antisense RNA 1
chr6_+_24495067 0.19 ENST00000357578.3
ENST00000546278.1
ENST00000491546.1
aldehyde dehydrogenase 5 family, member A1
chr6_+_31637944 0.19 ENST00000375864.4
lymphocyte antigen 6 complex, locus G5B
chr9_-_3489406 0.18 ENST00000457373.1
regulatory factor X, 3 (influences HLA class II expression)
chr7_-_141401951 0.18 ENST00000536163.1
KIAA1147
chr11_-_129817471 0.18 ENST00000423662.2
PR domain containing 10
chr7_-_56160625 0.18 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
phosphorylase kinase, gamma 1 (muscle)
chr17_-_46178527 0.18 ENST00000393408.3
chromobox homolog 1
chr12_-_2966193 0.18 ENST00000382678.3
Uncharacterized protein ENSP00000372125
chr6_+_147527103 0.18 ENST00000179882.6
syntaxin binding protein 5 (tomosyn)
chr6_-_33771757 0.18 ENST00000507738.1
ENST00000266003.5
ENST00000430124.2
motilin
chr7_-_107204918 0.17 ENST00000297135.3
component of oligomeric golgi complex 5
chr1_+_59775752 0.17 ENST00000371212.1
FGGY carbohydrate kinase domain containing
chr2_-_107084826 0.17 ENST00000304514.7
ENST00000409886.3
RANBP2-like and GRIP domain containing 3
chr11_+_111783450 0.17 ENST00000537382.1
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chr5_-_74162605 0.16 ENST00000389156.4
ENST00000510496.1
ENST00000380515.3
family with sequence similarity 169, member A
chr10_-_81203972 0.16 ENST00000372333.3
zinc finger, CCHC domain containing 24
chr1_+_75594119 0.16 ENST00000294638.5
LIM homeobox 8
chr6_-_31763721 0.16 ENST00000375663.3
valyl-tRNA synthetase
chr6_-_24667180 0.16 ENST00000545995.1
tyrosyl-DNA phosphodiesterase 2
chr3_-_121448791 0.16 ENST00000489400.1
golgin B1
chr22_-_21360736 0.16 ENST00000547793.2
Uncharacterized protein
chr19_-_15344243 0.15 ENST00000602233.1
epoxide hydrolase 3
chr14_+_89290965 0.15 ENST00000345383.5
ENST00000536576.1
ENST00000346301.4
ENST00000338104.6
ENST00000354441.6
ENST00000380656.2
ENST00000556651.1
ENST00000554686.1
tetratricopeptide repeat domain 8
chr4_+_8594477 0.15 ENST00000315782.6
carboxypeptidase Z
chr14_+_104710541 0.15 ENST00000419115.1
chromosome 14 open reading frame 144
chr11_-_111782484 0.15 ENST00000533971.1
crystallin, alpha B
chr11_-_116708302 0.15 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
apolipoprotein A-I
chr11_-_95522907 0.15 ENST00000358780.5
ENST00000542135.1
family with sequence similarity 76, member B
chr3_+_99986036 0.14 ENST00000471098.1
TBC1 domain family, member 23
chr2_-_152830479 0.14 ENST00000360283.6
calcium channel, voltage-dependent, beta 4 subunit
chr5_-_75008244 0.14 ENST00000510798.1
ENST00000446329.2
POC5 centriolar protein
chr4_-_84406218 0.14 ENST00000515303.1
family with sequence similarity 175, member A
chr17_-_46178741 0.14 ENST00000581003.1
ENST00000225603.4
chromobox homolog 1
chr22_+_24819565 0.14 ENST00000424232.1
ENST00000486108.1
adenosine A2a receptor
chr16_-_18923035 0.14 ENST00000563836.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr17_-_40828969 0.14 ENST00000591022.1
ENST00000587627.1
ENST00000293349.6
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr17_+_41363854 0.13 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
transmembrane protein 106A
chr1_+_174669653 0.13 ENST00000325589.5
RAB GTPase activating protein 1-like
chr17_+_58677539 0.13 ENST00000305921.3
protein phosphatase, Mg2+/Mn2+ dependent, 1D
chr17_-_40829026 0.13 ENST00000412503.1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr6_-_24667232 0.13 ENST00000378198.4
tyrosyl-DNA phosphodiesterase 2
chr9_+_104296243 0.13 ENST00000466817.1
ring finger protein 20, E3 ubiquitin protein ligase
chr17_-_28618948 0.13 ENST00000261714.6
bleomycin hydrolase
chr10_+_11784360 0.13 ENST00000379215.4
ENST00000420401.1
enoyl CoA hydratase domain containing 3
chr4_+_77177512 0.13 ENST00000606246.1
family with sequence similarity 47, member E
chr6_+_168434678 0.13 ENST00000496008.1
kinesin family member 25
chrX_-_14047996 0.12 ENST00000380523.4
ENST00000398355.3
gem (nuclear organelle) associated protein 8
chr6_+_76311636 0.12 ENST00000327284.8
SUMO1/sentrin specific peptidase 6
chr7_-_74489609 0.12 ENST00000329959.4
ENST00000503250.2
ENST00000543840.1
Williams-Beuren syndrome chromosome region 16
chr7_-_123198284 0.12 ENST00000355749.2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr2_+_88991162 0.12 ENST00000283646.4
ribose 5-phosphate isomerase A
chr22_-_43398442 0.12 ENST00000422336.1
protein kinase C and casein kinase substrate in neurons 2
chr14_-_80697396 0.11 ENST00000557010.1
deiodinase, iodothyronine, type II
chr8_+_91013676 0.11 ENST00000519410.1
ENST00000522161.1
ENST00000517761.1
ENST00000520227.1
2,4-dienoyl CoA reductase 1, mitochondrial
chr5_-_135290651 0.11 ENST00000522943.1
ENST00000514447.2
leukocyte cell-derived chemotaxin 2
chr11_+_63870660 0.11 ENST00000246841.3
fibronectin leucine rich transmembrane protein 1
chr17_+_76126842 0.11 ENST00000590426.1
ENST00000590799.1
ENST00000318430.5
ENST00000589691.1
transmembrane channel-like 8
chr11_+_118398178 0.11 ENST00000302783.4
ENST00000539546.1
tetratricopeptide repeat domain 36
chrX_+_56100757 0.11 ENST00000433279.1
Uncharacterized protein
chr11_+_111782934 0.10 ENST00000304298.3
Homo sapiens heat shock 27kDa protein 2 (HSPB2), mRNA.
chrX_+_73164167 0.10 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX transcript, XIST activator (non-protein coding)
chr8_+_13424352 0.10 ENST00000297324.4
chromosome 8 open reading frame 48
chr8_-_27462822 0.10 ENST00000522098.1
clusterin
chr11_+_61520075 0.10 ENST00000278836.5
myelin regulatory factor
chr18_-_32924372 0.10 ENST00000261332.6
ENST00000399061.3
zinc finger protein 24
chr16_-_21875424 0.10 ENST00000541674.1
nuclear pore complex interacting protein family, member B4
chr1_+_17944832 0.10 ENST00000167825.4
Rho guanine nucleotide exchange factor (GEF) 10-like
chr14_+_62164340 0.09 ENST00000557538.1
ENST00000539097.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr4_+_8594435 0.09 ENST00000382480.2
carboxypeptidase Z
chr9_-_125590818 0.09 ENST00000259467.4
phosducin-like
chr19_-_11688260 0.09 ENST00000590832.1
acid phosphatase 5, tartrate resistant
chr1_+_150898733 0.09 ENST00000525956.1
SET domain, bifurcated 1
chr9_-_100459639 0.09 ENST00000375128.4
xeroderma pigmentosum, complementation group A
chr11_-_62476694 0.08 ENST00000524862.1
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr17_+_26800756 0.08 ENST00000537681.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr20_-_5485166 0.08 ENST00000589201.1
ENST00000379053.4
long intergenic non-protein coding RNA 654
chr17_+_26800648 0.08 ENST00000545060.1
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr8_+_8860314 0.08 ENST00000250263.7
ENST00000519292.1
exoribonuclease 1
chr3_-_49837254 0.08 ENST00000412678.2
ENST00000343366.4
ENST00000487256.1
cadherin-related family member 4
chr12_-_323248 0.08 ENST00000535347.1
ENST00000536824.1
solute carrier family 6 (neurotransmitter transporter), member 12
chr4_+_8594364 0.08 ENST00000360986.4
carboxypeptidase Z
chr6_-_31763408 0.08 ENST00000444930.2
valyl-tRNA synthetase
chr3_-_64009658 0.08 ENST00000394431.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr5_+_147774275 0.08 ENST00000513826.1
F-box protein 38
chr10_-_61899124 0.08 ENST00000373815.1
ankyrin 3, node of Ranvier (ankyrin G)
chr16_+_2106134 0.07 ENST00000467949.1
tuberous sclerosis 2
chr17_+_78518617 0.07 ENST00000537330.1
ENST00000570891.1
regulatory associated protein of MTOR, complex 1
chr11_-_798305 0.07 ENST00000531514.1
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr12_-_76377795 0.07 ENST00000552856.1
RP11-114H23.1
chrX_+_73164149 0.07 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX transcript, XIST activator (non-protein coding)
chrX_+_102024075 0.07 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
long intergenic non-protein coding RNA 630
chr5_-_74162739 0.07 ENST00000513277.1
family with sequence similarity 169, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of RARB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.3 1.0 GO:0030070 insulin processing(GO:0030070)
0.3 0.9 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.7 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.2 1.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.2 0.6 GO:0019860 uracil metabolic process(GO:0019860)
0.2 1.1 GO:0070383 DNA cytosine deamination(GO:0070383)
0.1 0.7 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.8 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.1 0.3 GO:0006043 glucosamine catabolic process(GO:0006043)
0.1 0.2 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.4 GO:0060032 notochord regression(GO:0060032)
0.1 1.8 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.4 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.8 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.1 0.6 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.4 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.1 1.8 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.1 0.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.1 0.3 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512) L-kynurenine metabolic process(GO:0097052)
0.1 0.4 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.0 0.1 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903) regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.2 GO:0002071 glandular epithelial cell maturation(GO:0002071) type B pancreatic cell maturation(GO:0072560)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.3 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 1.4 GO:0019054 modulation by virus of host process(GO:0019054)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.2 GO:0000101 sulfur amino acid transport(GO:0000101) L-cystine transport(GO:0015811)
0.0 1.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.5 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014) pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.2 GO:0050893 sensory processing(GO:0050893)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.5 GO:1901685 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.5 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.0 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0044854 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.0 0.0 GO:0048808 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.1 0.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0098536 deuterosome(GO:0098536)
0.1 0.2 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 1.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.9 GO:0051233 spindle midzone(GO:0051233)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.4 GO:0018995 host(GO:0018995) host cell(GO:0043657)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 1.6 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 0.6 GO:0070538 oleic acid binding(GO:0070538)
0.2 0.5 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 1.0 GO:0016936 galactoside binding(GO:0016936)
0.1 1.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.3 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 0.3 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.1 0.3 GO:0070260 tyrosyl-RNA phosphodiesterase activity(GO:0036317) 5'-tyrosyl-DNA phosphodiesterase activity(GO:0070260)
0.1 1.0 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.8 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.4 GO:1904408 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.6 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.4 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 1.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.0 0.1 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.3 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.3 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.0 GO:0015297 antiporter activity(GO:0015297)
0.0 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 1.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.1 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects