Project

A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for PRRX1_ALX4_PHOX2A

Z-value: 0.55

Motif logo

logo of logo of logo of

Transcription factors associated with PRRX1_ALX4_PHOX2A

Gene Symbol Gene ID Gene Info
PRRX1
ENSG00000116132.7 paired related homeobox 1
ALX4
ENSG00000052850.5 ALX homeobox 4
PHOX2A
ENSG00000165462.5 paired like homeobox 2A

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ALX4hg19_v2_chr11_-_44331679_44331716-0.633.7e-01Click!
PRRX1hg19_v2_chr1_+_170633047_170633084-0.336.7e-01Click!

Activity profile of PRRX1_ALX4_PHOX2A motif

Sorted Z-values of PRRX1_ALX4_PHOX2A motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_195310802 1.04 ENST00000421243.1
ENST00000453131.1
APOD
apolipoprotein D
chr4_+_155484155 0.97 ENST00000509493.1
FGB
fibrinogen beta chain
chr7_+_30589829 0.91 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr8_-_95229531 0.86 ENST00000450165.2
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr4_-_76649546 0.82 ENST00000508510.1
ENST00000509561.1
ENST00000499709.2
ENST00000511868.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr6_+_26087646 0.81 ENST00000309234.6
HFE
hemochromatosis
chr4_+_155484103 0.79 ENST00000302068.4
FGB
fibrinogen beta chain
chr7_-_111032971 0.78 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr6_-_32908792 0.68 ENST00000418107.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_107235331 0.49 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr11_+_1295809 0.47 ENST00000598274.1
AC136297.1
Uncharacterized protein
chr1_-_200379180 0.46 ENST00000294740.3
ZNF281
zinc finger protein 281
chr6_-_32908765 0.45 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr1_-_241799232 0.45 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr3_-_27764190 0.45 ENST00000537516.1
EOMES
eomesodermin
chr12_+_14572070 0.44 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr1_-_151148492 0.44 ENST00000295314.4
TMOD4
tropomodulin 4 (muscle)
chr18_+_20714525 0.41 ENST00000400473.2
CABLES1
Cdk5 and Abl enzyme substrate 1
chr2_-_114461655 0.41 ENST00000424612.1
AC017074.2
AC017074.2
chr4_+_113568207 0.40 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr14_-_38064198 0.40 ENST00000250448.2
FOXA1
forkhead box A1
chrX_+_77166172 0.37 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr16_+_53412368 0.37 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr6_-_107235378 0.35 ENST00000606430.1
RP1-60O19.1
RP1-60O19.1
chr6_-_107235287 0.35 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1
RP1-60O19.1
chr3_-_87325612 0.34 ENST00000561167.1
ENST00000560656.1
ENST00000344265.3
POU1F1
POU class 1 homeobox 1
chr2_+_44001172 0.33 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
DYNC2LI1
dynein, cytoplasmic 2, light intermediate chain 1
chr14_+_38065052 0.30 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr3_+_149192475 0.30 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr14_-_83262540 0.30 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chr15_-_76304731 0.29 ENST00000394907.3
NRG4
neuregulin 4
chr3_+_149191723 0.29 ENST00000305354.4
TM4SF4
transmembrane 4 L six family member 4
chr1_-_234667504 0.28 ENST00000421207.1
ENST00000435574.1
RP5-855F14.1
RP5-855F14.1
chr7_-_55620433 0.27 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr1_+_183774240 0.26 ENST00000360851.3
RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr16_+_53133070 0.26 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr8_-_17752912 0.25 ENST00000398054.1
ENST00000381840.2
FGL1
fibrinogen-like 1
chr3_-_186262166 0.24 ENST00000307944.5
CRYGS
crystallin, gamma S
chr8_-_17752996 0.24 ENST00000381841.2
ENST00000427924.1
FGL1
fibrinogen-like 1
chr8_-_102803163 0.24 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr1_-_151148442 0.24 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chr11_-_96076334 0.22 ENST00000524717.1
MAML2
mastermind-like 2 (Drosophila)
chr5_+_140514782 0.22 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr2_-_55496174 0.21 ENST00000417363.1
ENST00000412530.1
ENST00000394600.3
ENST00000366137.2
ENST00000420637.1
MTIF2
mitochondrial translational initiation factor 2
chr3_+_153839149 0.21 ENST00000465093.1
ENST00000465817.1
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr17_-_39156138 0.21 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr8_+_107738240 0.21 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr3_-_9291063 0.21 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr15_-_37393406 0.20 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2
Meis homeobox 2
chr12_-_49581152 0.19 ENST00000550811.1
TUBA1A
tubulin, alpha 1a
chr4_+_48485341 0.19 ENST00000273861.4
SLC10A4
solute carrier family 10, member 4
chr17_+_53342311 0.19 ENST00000226067.5
HLF
hepatic leukemia factor
chr8_-_124741451 0.18 ENST00000520519.1
ANXA13
annexin A13
chr4_+_54927213 0.18 ENST00000595906.1
AC110792.1
HCG2027126; Uncharacterized protein
chr7_-_140482926 0.18 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr4_+_109571740 0.18 ENST00000361564.4
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr7_-_35013217 0.18 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr12_+_49621658 0.18 ENST00000541364.1
TUBA1C
tubulin, alpha 1c
chr15_+_57511609 0.17 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr4_+_76649797 0.17 ENST00000538159.1
ENST00000514213.2
USO1
USO1 vesicle transport factor
chrX_+_119737806 0.17 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr12_-_118628350 0.17 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr5_+_136070614 0.17 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr1_+_50459990 0.16 ENST00000448346.1
AL645730.2
AL645730.2
chr3_-_130465604 0.16 ENST00000356763.3
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr6_+_3259122 0.16 ENST00000438998.2
ENST00000380305.4
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr5_-_134735568 0.16 ENST00000510038.1
ENST00000304332.4
H2AFY
H2A histone family, member Y
chr12_-_91573132 0.15 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr2_+_32390925 0.15 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr2_-_58468437 0.15 ENST00000403676.1
ENST00000427708.2
ENST00000403295.3
ENST00000446381.1
ENST00000417361.1
ENST00000233741.4
ENST00000402135.3
ENST00000540646.1
ENST00000449070.1
FANCL
Fanconi anemia, complementation group L
chr15_-_34331243 0.15 ENST00000306730.3
AVEN
apoptosis, caspase activation inhibitor
chr5_-_111093759 0.15 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
NREP
neuronal regeneration related protein
chr2_+_191334212 0.14 ENST00000444317.1
ENST00000535751.1
MFSD6
major facilitator superfamily domain containing 6
chr16_+_21244986 0.14 ENST00000311620.5
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr1_+_154401791 0.14 ENST00000476006.1
IL6R
interleukin 6 receptor
chr15_-_75748143 0.13 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A
SIN3 transcription regulator family member A
chr1_-_26231589 0.13 ENST00000374291.1
STMN1
stathmin 1
chrX_+_149887090 0.13 ENST00000538506.1
MTMR1
myotubularin related protein 1
chr19_+_50016610 0.13 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr4_+_76649753 0.13 ENST00000603759.1
USO1
USO1 vesicle transport factor
chr9_+_42671887 0.13 ENST00000456520.1
ENST00000377391.3
CBWD7
COBW domain containing 7
chr1_+_81106951 0.13 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr9_+_124329336 0.13 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr1_-_242162375 0.13 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr14_-_57197224 0.13 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr1_+_62439037 0.12 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr6_+_3259148 0.12 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr12_-_118796910 0.12 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr5_-_70272055 0.12 ENST00000514857.2
NAIP
NLR family, apoptosis inhibitory protein
chr8_+_26150628 0.12 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr11_-_63439013 0.12 ENST00000398868.3
ATL3
atlastin GTPase 3
chr4_+_109571800 0.12 ENST00000512478.2
OSTC
oligosaccharyltransferase complex subunit (non-catalytic)
chr3_-_11623804 0.12 ENST00000451674.2
VGLL4
vestigial like 4 (Drosophila)
chr5_-_87516448 0.12 ENST00000511218.1
TMEM161B
transmembrane protein 161B
chr8_+_107738343 0.11 ENST00000521592.1
OXR1
oxidation resistance 1
chr19_-_49149553 0.11 ENST00000084798.4
CA11
carbonic anhydrase XI
chr22_+_25615489 0.11 ENST00000398215.2
CRYBB2
crystallin, beta B2
chr17_-_39023462 0.11 ENST00000251643.4
KRT12
keratin 12
chr12_-_107380846 0.11 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERFD3
MTERF domain containing 3
chr12_-_118796971 0.11 ENST00000542902.1
TAOK3
TAO kinase 3
chr1_-_200379129 0.11 ENST00000367353.1
ZNF281
zinc finger protein 281
chr12_-_10978957 0.11 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr8_+_87111059 0.11 ENST00000285393.3
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr14_+_88851874 0.11 ENST00000393545.4
ENST00000356583.5
ENST00000555401.1
ENST00000553885.1
SPATA7
spermatogenesis associated 7
chr17_+_44701402 0.10 ENST00000575068.1
NSF
N-ethylmaleimide-sensitive factor
chr17_+_71228740 0.10 ENST00000268942.8
ENST00000359042.2
C17orf80
chromosome 17 open reading frame 80
chr21_+_17442799 0.10 ENST00000602580.1
ENST00000458468.1
ENST00000602935.1
LINC00478
long intergenic non-protein coding RNA 478
chrX_-_48858630 0.10 ENST00000376425.3
ENST00000376444.3
GRIPAP1
GRIP1 associated protein 1
chr14_+_24099318 0.10 ENST00000432832.2
DHRS2
dehydrogenase/reductase (SDR family) member 2
chr20_+_31823792 0.10 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1
BPI fold containing family A, member 1
chr9_-_123639445 0.10 ENST00000312189.6
PHF19
PHD finger protein 19
chr17_-_56494908 0.10 ENST00000577716.1
RNF43
ring finger protein 43
chr6_+_44187242 0.10 ENST00000393844.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr7_+_55980331 0.10 ENST00000429591.2
ZNF713
zinc finger protein 713
chr6_-_41039567 0.10 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chr16_+_53469525 0.10 ENST00000544405.2
RBL2
retinoblastoma-like 2 (p130)
chr3_-_33759699 0.09 ENST00000399362.4
ENST00000359576.5
ENST00000307312.7
CLASP2
cytoplasmic linker associated protein 2
chr9_-_123639304 0.09 ENST00000436309.1
PHF19
PHD finger protein 19
chr6_+_44187334 0.09 ENST00000313248.7
ENST00000427851.2
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr4_+_165878100 0.09 ENST00000513876.2
FAM218A
family with sequence similarity 218, member A
chr10_+_18689637 0.09 ENST00000377315.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_-_76072719 0.09 ENST00000370020.1
FILIP1
filamin A interacting protein 1
chr1_+_212475148 0.09 ENST00000537030.3
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr2_-_145275828 0.09 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr3_-_197300194 0.09 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr9_-_71869642 0.09 ENST00000600472.1
AL358113.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr4_+_142558078 0.09 ENST00000529613.1
IL15
interleukin 15
chr21_-_43346790 0.09 ENST00000329623.7
C2CD2
C2 calcium-dependent domain containing 2
chrX_-_48858667 0.08 ENST00000376423.4
ENST00000376441.1
GRIPAP1
GRIP1 associated protein 1
chr11_-_92931098 0.08 ENST00000326402.4
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr3_-_32544900 0.08 ENST00000205636.3
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr12_+_58003935 0.08 ENST00000333972.7
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr11_+_66276550 0.08 ENST00000419755.3
CTD-3074O7.11
Bardet-Biedl syndrome 1 protein
chr10_-_105110890 0.08 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr10_-_75226166 0.08 ENST00000544628.1
PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chrX_-_68385354 0.08 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr5_+_133562095 0.08 ENST00000602919.1
CTD-2410N18.3
CTD-2410N18.3
chr1_+_170115142 0.08 ENST00000439373.2
METTL11B
methyltransferase like 11B
chr10_-_105110831 0.08 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr12_-_107380910 0.08 ENST00000392830.2
ENST00000240050.4
MTERFD3
MTERF domain containing 3
chr5_-_142780280 0.08 ENST00000424646.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr9_-_39239171 0.07 ENST00000358144.2
CNTNAP3
contactin associated protein-like 3
chr11_+_18433840 0.07 ENST00000541669.1
ENST00000280704.4
LDHC
lactate dehydrogenase C
chr12_+_116985896 0.07 ENST00000547114.1
RP11-809C9.2
RP11-809C9.2
chr14_-_21567009 0.07 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr7_+_138145076 0.07 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr6_+_88106840 0.07 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr9_+_2159850 0.07 ENST00000416751.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_+_52155001 0.07 ENST00000544199.1
TMOD3
tropomodulin 3 (ubiquitous)
chr9_-_123639600 0.07 ENST00000373896.3
PHF19
PHD finger protein 19
chr12_+_20968608 0.07 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
LST3
SLCO1B3
SLCO1B7
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr12_-_16761117 0.07 ENST00000538051.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_+_136501478 0.07 ENST00000393056.2
ENST00000263611.2
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr5_+_68860949 0.07 ENST00000507595.1
GTF2H2C
general transcription factor IIH, polypeptide 2C
chr17_-_79623597 0.07 ENST00000574024.1
ENST00000331056.5
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr11_-_111649015 0.07 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr3_+_151591422 0.06 ENST00000362032.5
SUCNR1
succinate receptor 1
chr7_-_27169801 0.06 ENST00000511914.1
HOXA4
homeobox A4
chr17_+_71228537 0.06 ENST00000577615.1
ENST00000585109.1
C17orf80
chromosome 17 open reading frame 80
chr12_+_72061563 0.06 ENST00000551238.1
THAP2
THAP domain containing, apoptosis associated protein 2
chrX_-_68385274 0.06 ENST00000374584.3
ENST00000590146.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr9_-_215744 0.06 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr12_-_118628315 0.06 ENST00000540561.1
TAOK3
TAO kinase 3
chr15_+_75628394 0.06 ENST00000564815.1
ENST00000338995.6
COMMD4
COMM domain containing 4
chr12_-_53601000 0.06 ENST00000338737.4
ENST00000549086.2
ITGB7
integrin, beta 7
chr2_-_183291741 0.06 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr14_+_39734482 0.06 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE5
CTAGE family, member 5
chr15_-_52970820 0.06 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
FAM214A
family with sequence similarity 214, member A
chr15_+_93426514 0.06 ENST00000556722.1
CHD2
chromodomain helicase DNA binding protein 2
chrX_+_9431324 0.06 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr10_+_67330096 0.06 ENST00000433152.4
ENST00000601979.1
ENST00000599409.1
ENST00000608678.1
RP11-222A11.1
RP11-222A11.1
chr2_-_175711133 0.06 ENST00000409597.1
ENST00000413882.1
CHN1
chimerin 1
chr9_-_95244781 0.06 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr5_-_54603368 0.06 ENST00000508346.1
ENST00000251636.5
DHX29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr15_+_75628232 0.06 ENST00000267935.8
ENST00000567195.1
COMMD4
COMM domain containing 4
chr8_-_80942061 0.06 ENST00000519386.1
MRPS28
mitochondrial ribosomal protein S28
chr2_+_223725652 0.05 ENST00000357430.3
ENST00000392066.3
ACSL3
acyl-CoA synthetase long-chain family member 3
chr3_+_140660634 0.05 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
SLC25A36
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr9_-_95298314 0.05 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr1_+_186798073 0.05 ENST00000367466.3
ENST00000442353.2
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr18_-_13915530 0.05 ENST00000327606.3
MC2R
melanocortin 2 receptor (adrenocorticotropic hormone)
chr1_+_145525015 0.05 ENST00000539363.1
ENST00000538811.1
ITGA10
integrin, alpha 10
chr1_+_180601139 0.05 ENST00000367590.4
ENST00000367589.3
XPR1
xenotropic and polytropic retrovirus receptor 1
chr12_+_100897130 0.05 ENST00000551379.1
ENST00000188403.7
ENST00000551184.1
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr5_+_36152163 0.05 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr12_-_15815626 0.05 ENST00000540613.1
EPS8
epidermal growth factor receptor pathway substrate 8
chr14_+_21566980 0.05 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr11_-_82681626 0.05 ENST00000534396.1
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr17_-_5321549 0.05 ENST00000572809.1
NUP88
nucleoporin 88kDa
chr5_-_111312622 0.05 ENST00000395634.3
NREP
neuronal regeneration related protein
chr13_-_26795840 0.05 ENST00000381570.3
ENST00000399762.2
ENST00000346166.3
RNF6
ring finger protein (C3H2C3 type) 6
chr10_+_89420706 0.05 ENST00000427144.2
PAPSS2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr11_+_43333513 0.05 ENST00000534695.1
ENST00000455725.2
ENST00000531273.1
ENST00000420461.2
ENST00000378852.3
ENST00000534600.1
API5
apoptosis inhibitor 5
chr2_-_70529180 0.05 ENST00000450256.1
ENST00000037869.3
FAM136A
family with sequence similarity 136, member A
chr2_+_36923830 0.05 ENST00000379242.3
ENST00000389975.3
VIT
vitrin
chr9_-_27005686 0.05 ENST00000380055.5
LRRC19
leucine rich repeat containing 19
chrX_+_48687283 0.04 ENST00000338270.1
ERAS
ES cell expressed Ras
chr2_+_170440844 0.04 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr4_-_83769996 0.04 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr1_-_209957882 0.04 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74

Network of associatons between targets according to the STRING database.

First level regulatory network of PRRX1_ALX4_PHOX2A

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:2001190 peptide antigen assembly with MHC class II protein complex(GO:0002503) positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.4 0.4 GO:0034756 regulation of iron ion transport(GO:0034756) regulation of iron ion transmembrane transport(GO:0034759)
0.3 0.8 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.3 1.0 GO:2000097 negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 0.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 0.9 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 1.8 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.4 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.7 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.3 GO:0060133 somatotropin secreting cell development(GO:0060133)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:1904815 negative regulation of protein localization to chromosome, telomeric region(GO:1904815)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.8 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.2 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.2 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0045062 extrathymic T cell selection(GO:0045062)
0.0 0.1 GO:0019516 lactate oxidation(GO:0019516)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.2 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.7 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.0 0.1 GO:0006480 N-terminal protein amino acid methylation(GO:0006480)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0002386 immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0 0.2 GO:0018211 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.4 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.1 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:2000213 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.0 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.0 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.2 2.2 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.8 GO:1990357 terminal web(GO:1990357)
0.1 1.1 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:1990032 parallel fiber(GO:1990032)
0.0 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.0 GO:0070993 translation preinitiation complex(GO:0070993)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.0 0.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 0.9 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.4 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.1 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 1.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 1.8 GO:0051087 chaperone binding(GO:0051087)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling