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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PROX1

Z-value: 0.88

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Transcription factors associated with PROX1

Gene Symbol Gene ID Gene Info
PROX1
ENSG00000117707.11 prospero homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROX1hg19_v2_chr1_+_214161272_214161322-0.982.4e-02Click!

Activity profile of PROX1 motif

Sorted Z-values of PROX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_57308979 1.42 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr12_+_42624050 0.96 ENST00000601185.1
AC020629.1
Uncharacterized protein
chr8_+_142264664 0.59 ENST00000518520.1
RP11-10J21.3
Uncharacterized protein
chr12_+_52668394 0.58 ENST00000423955.2
KRT86
keratin 86
chr3_+_136676707 0.58 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr16_+_31724618 0.57 ENST00000530881.1
ENST00000529515.1
ZNF720
zinc finger protein 720
chr3_-_122283424 0.57 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr16_+_85832146 0.57 ENST00000565078.1
COX4I1
cytochrome c oxidase subunit IV isoform 1
chr22_-_39640756 0.51 ENST00000331163.6
PDGFB
platelet-derived growth factor beta polypeptide
chr21_-_16125773 0.50 ENST00000454128.2
AF127936.3
AF127936.3
chr19_-_45909585 0.50 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr5_-_157002775 0.49 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr2_-_233877912 0.49 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chr6_+_90192974 0.46 ENST00000520458.1
ANKRD6
ankyrin repeat domain 6
chr7_+_48128316 0.45 ENST00000341253.4
UPP1
uridine phosphorylase 1
chr7_+_48128194 0.45 ENST00000416681.1
ENST00000331803.4
ENST00000432131.1
UPP1
uridine phosphorylase 1
chr20_-_61885826 0.45 ENST00000370316.3
NKAIN4
Na+/K+ transporting ATPase interacting 4
chr19_-_48018203 0.44 ENST00000595227.1
ENST00000593761.1
ENST00000263354.3
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr2_-_163175133 0.44 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr1_-_109399682 0.43 ENST00000369995.3
ENST00000370001.3
AKNAD1
AKNA domain containing 1
chr8_+_145064233 0.43 ENST00000529301.1
ENST00000395068.4
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr8_+_145064215 0.41 ENST00000313269.5
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr18_-_2571210 0.39 ENST00000577166.1
METTL4
methyltransferase like 4
chr8_-_19615538 0.39 ENST00000517494.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr5_-_157002749 0.38 ENST00000517905.1
ENST00000430702.2
ENST00000394020.1
ADAM19
ADAM metallopeptidase domain 19
chr3_-_48723268 0.38 ENST00000439518.1
ENST00000416649.2
ENST00000341520.4
ENST00000294129.2
NCKIPSD
NCK interacting protein with SH3 domain
chr19_-_40732594 0.37 ENST00000430325.2
ENST00000433940.1
CNTD2
cyclin N-terminal domain containing 2
chr18_-_21166841 0.37 ENST00000269228.5
NPC1
Niemann-Pick disease, type C1
chr22_-_45559540 0.37 ENST00000432502.1
CTA-217C2.1
CTA-217C2.1
chr22_+_18121356 0.36 ENST00000317582.5
ENST00000543133.1
ENST00000538149.1
ENST00000337612.5
ENST00000493680.1
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr7_+_128864848 0.36 ENST00000325006.3
ENST00000446544.2
AHCYL2
adenosylhomocysteinase-like 2
chr8_-_19615435 0.35 ENST00000523262.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr3_-_27410847 0.32 ENST00000429845.2
ENST00000341435.5
ENST00000435750.1
NEK10
NIMA-related kinase 10
chr17_+_77018896 0.32 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr5_+_175490540 0.32 ENST00000515817.1
FAM153B
family with sequence similarity 153, member B
chr19_-_12267524 0.30 ENST00000455799.1
ENST00000355738.1
ENST00000439556.2
ENST00000542938.1
ZNF625
zinc finger protein 625
chr4_-_170947485 0.30 ENST00000504999.1
MFAP3L
microfibrillar-associated protein 3-like
chr3_-_25915189 0.30 ENST00000451284.1
LINC00692
long intergenic non-protein coding RNA 692
chr22_-_45559642 0.30 ENST00000426282.2
CTA-217C2.1
CTA-217C2.1
chr12_+_10331605 0.29 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr15_-_78913628 0.29 ENST00000348639.3
CHRNA3
cholinergic receptor, nicotinic, alpha 3 (neuronal)
chr4_+_4861385 0.29 ENST00000382723.4
MSX1
msh homeobox 1
chr14_-_36645674 0.28 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr16_+_28857916 0.28 ENST00000563591.1
SH2B1
SH2B adaptor protein 1
chr3_-_196065248 0.28 ENST00000446879.1
ENST00000273695.3
TM4SF19
transmembrane 4 L six family member 19
chr7_+_100209979 0.27 ENST00000493970.1
ENST00000379527.2
MOSPD3
motile sperm domain containing 3
chr7_-_143582450 0.27 ENST00000485416.1
FAM115A
family with sequence similarity 115, member A
chr7_+_100210133 0.27 ENST00000393950.2
ENST00000424091.2
MOSPD3
motile sperm domain containing 3
chr1_-_28241024 0.27 ENST00000313433.7
ENST00000444045.1
RPA2
replication protein A2, 32kDa
chr2_+_131862872 0.27 ENST00000439822.2
PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr1_-_201476274 0.27 ENST00000340006.2
CSRP1
cysteine and glycine-rich protein 1
chr16_+_58059470 0.27 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr6_+_126102292 0.26 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr3_+_138067314 0.26 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chr22_+_45559722 0.26 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
NUP50
nucleoporin 50kDa
chr1_-_201476220 0.25 ENST00000526723.1
ENST00000524951.1
CSRP1
cysteine and glycine-rich protein 1
chr9_+_132096166 0.24 ENST00000436710.1
RP11-65J3.1
RP11-65J3.1
chr19_+_4007644 0.24 ENST00000262971.2
PIAS4
protein inhibitor of activated STAT, 4
chr6_+_144665237 0.24 ENST00000421035.2
UTRN
utrophin
chr22_+_18121562 0.24 ENST00000355028.3
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr9_+_95858485 0.23 ENST00000375464.2
C9orf89
chromosome 9 open reading frame 89
chr16_+_28985542 0.23 ENST00000567771.1
ENST00000568388.1
SPNS1
spinster homolog 1 (Drosophila)
chr1_-_44497118 0.23 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr4_+_128886532 0.23 ENST00000444616.1
ENST00000388795.5
C4orf29
chromosome 4 open reading frame 29
chr2_+_131862900 0.22 ENST00000438882.2
ENST00000538982.1
ENST00000404460.1
PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr2_+_108443388 0.22 ENST00000354986.4
ENST00000408999.3
RGPD4
RANBP2-like and GRIP domain containing 4
chr7_+_100209725 0.22 ENST00000223054.4
MOSPD3
motile sperm domain containing 3
chr12_+_54402790 0.22 ENST00000040584.4
HOXC8
homeobox C8
chr1_-_28241226 0.22 ENST00000373912.3
ENST00000373909.3
RPA2
replication protein A2, 32kDa
chr5_+_179125368 0.22 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
CANX
calnexin
chr1_+_171454639 0.22 ENST00000392078.3
ENST00000426496.2
PRRC2C
proline-rich coiled-coil 2C
chr17_+_72209653 0.22 ENST00000269346.4
TTYH2
tweety family member 2
chr10_+_45869652 0.21 ENST00000542434.1
ENST00000374391.2
ALOX5
arachidonate 5-lipoxygenase
chr2_-_97534312 0.21 ENST00000442264.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr11_-_57298187 0.20 ENST00000525158.1
ENST00000257245.4
ENST00000525587.1
TIMM10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr7_+_1609765 0.20 ENST00000437964.1
ENST00000533935.1
ENST00000532358.1
ENST00000524978.1
PSMG3-AS1
PSMG3 antisense RNA 1 (head to head)
chr10_-_94301107 0.20 ENST00000436178.1
IDE
insulin-degrading enzyme
chr22_-_43539346 0.20 ENST00000327555.5
ENST00000290429.6
MCAT
malonyl CoA:ACP acyltransferase (mitochondrial)
chrX_-_153236620 0.20 ENST00000369984.4
HCFC1
host cell factor C1 (VP16-accessory protein)
chr11_-_59383617 0.19 ENST00000263847.1
OSBP
oxysterol binding protein
chr11_+_1874200 0.19 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr2_+_241499719 0.19 ENST00000405954.1
DUSP28
dual specificity phosphatase 28
chr6_-_72129806 0.19 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr6_-_134495992 0.19 ENST00000475719.2
ENST00000367857.5
ENST00000237305.7
SGK1
serum/glucocorticoid regulated kinase 1
chr19_-_46234119 0.19 ENST00000317683.3
FBXO46
F-box protein 46
chr4_-_69215699 0.19 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr16_-_22012419 0.19 ENST00000537222.2
ENST00000424898.2
ENST00000286143.6
PDZD9
PDZ domain containing 9
chr8_-_19615382 0.19 ENST00000544602.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr10_+_71075552 0.19 ENST00000298649.3
HK1
hexokinase 1
chr3_-_33138592 0.18 ENST00000415454.1
GLB1
galactosidase, beta 1
chrX_-_153236819 0.18 ENST00000354233.3
HCFC1
host cell factor C1 (VP16-accessory protein)
chr11_-_73882029 0.18 ENST00000539061.1
C2CD3
C2 calcium-dependent domain containing 3
chr2_+_28618532 0.18 ENST00000545753.1
FOSL2
FOS-like antigen 2
chrX_-_153237258 0.18 ENST00000310441.7
HCFC1
host cell factor C1 (VP16-accessory protein)
chr2_-_239140011 0.17 ENST00000409376.1
ENST00000409070.1
ENST00000409942.1
AC016757.3
Protein LOC151174
chr12_+_113229737 0.17 ENST00000551052.1
ENST00000415485.3
RPH3A
rabphilin 3A homolog (mouse)
chr22_-_36761081 0.17 ENST00000456729.1
ENST00000401701.1
MYH9
myosin, heavy chain 9, non-muscle
chr19_-_16582815 0.17 ENST00000455140.2
ENST00000248070.6
ENST00000594975.1
EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
chr19_+_49535169 0.17 ENST00000474913.1
ENST00000359342.6
CGB2
chorionic gonadotropin, beta polypeptide 2
chr1_-_44497024 0.16 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr9_+_75136717 0.16 ENST00000297784.5
TMC1
transmembrane channel-like 1
chrY_+_22918021 0.16 ENST00000288666.5
RPS4Y2
ribosomal protein S4, Y-linked 2
chr12_+_121078355 0.16 ENST00000316803.3
CABP1
calcium binding protein 1
chr11_+_64008525 0.16 ENST00000449942.2
FKBP2
FK506 binding protein 2, 13kDa
chr17_-_36904437 0.16 ENST00000585100.1
ENST00000360797.2
ENST00000578109.1
ENST00000579882.1
PCGF2
polycomb group ring finger 2
chr2_-_65659762 0.16 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr14_+_78266408 0.16 ENST00000238561.5
ADCK1
aarF domain containing kinase 1
chr21_-_16126181 0.16 ENST00000455253.2
AF127936.3
AF127936.3
chr14_+_73603126 0.16 ENST00000557356.1
ENST00000556864.1
ENST00000556533.1
ENST00000556951.1
ENST00000557293.1
ENST00000553719.1
ENST00000553599.1
ENST00000556011.1
ENST00000394157.3
ENST00000357710.4
ENST00000324501.5
ENST00000560005.2
ENST00000555254.1
ENST00000261970.3
ENST00000344094.3
ENST00000554131.1
ENST00000557037.1
PSEN1
presenilin 1
chr8_-_41166953 0.15 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chr16_+_30669720 0.15 ENST00000356166.6
FBRS
fibrosin
chr11_-_111749767 0.15 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr1_+_95975672 0.15 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr6_+_34725263 0.15 ENST00000374018.1
ENST00000374017.3
SNRPC
small nuclear ribonucleoprotein polypeptide C
chr19_-_53324884 0.15 ENST00000457749.2
ENST00000414252.2
ENST00000391783.2
ZNF28
zinc finger protein 28
chr10_-_52008313 0.15 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr16_-_12070468 0.15 ENST00000538896.1
RP11-166B2.1
Putative NPIP-like protein LOC729978
chr2_-_239140276 0.15 ENST00000334973.4
AC016757.3
Protein LOC151174
chr19_+_6361754 0.15 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr12_+_113229543 0.15 ENST00000447659.2
RPH3A
rabphilin 3A homolog (mouse)
chr10_+_60028818 0.14 ENST00000333926.5
CISD1
CDGSH iron sulfur domain 1
chr1_+_10459111 0.14 ENST00000541529.1
ENST00000270776.8
ENST00000483936.1
ENST00000538557.1
PGD
phosphogluconate dehydrogenase
chrX_-_53461305 0.14 ENST00000168216.6
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chrX_+_150565038 0.14 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr5_-_22853429 0.14 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr11_+_61722629 0.14 ENST00000526988.1
BEST1
bestrophin 1
chr6_+_170151708 0.13 ENST00000592367.1
ENST00000590711.1
ENST00000366772.2
ENST00000592745.1
ENST00000392095.4
ENST00000366773.3
ENST00000586341.1
ENST00000418781.3
ENST00000588437.1
ERMARD
ER membrane-associated RNA degradation
chr16_+_22518495 0.13 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr6_+_170151887 0.13 ENST00000588451.1
ERMARD
ER membrane-associated RNA degradation
chr4_+_128886424 0.13 ENST00000398965.1
C4orf29
chromosome 4 open reading frame 29
chr3_-_137834436 0.12 ENST00000327532.2
ENST00000467030.1
DZIP1L
DAZ interacting zinc finger protein 1-like
chr8_+_117963190 0.12 ENST00000427715.2
SLC30A8
solute carrier family 30 (zinc transporter), member 8
chr11_-_64739542 0.12 ENST00000536065.1
C11orf85
chromosome 11 open reading frame 85
chr12_+_113229452 0.12 ENST00000389385.4
RPH3A
rabphilin 3A homolog (mouse)
chr5_+_177433973 0.12 ENST00000507848.1
FAM153C
family with sequence similarity 153, member C
chr6_-_159420780 0.12 ENST00000449822.1
RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr11_+_60609537 0.12 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr19_-_19754404 0.11 ENST00000587205.1
ENST00000445806.2
ENST00000203556.4
GMIP
GEM interacting protein
chrX_+_49019061 0.11 ENST00000376339.1
ENST00000425661.2
ENST00000458388.1
ENST00000412696.2
MAGIX
MAGI family member, X-linked
chr22_-_32058166 0.11 ENST00000435900.1
ENST00000336566.4
PISD
phosphatidylserine decarboxylase
chr9_-_130890662 0.11 ENST00000277462.5
ENST00000338961.6
PTGES2
prostaglandin E synthase 2
chr11_-_58035732 0.11 ENST00000395079.2
OR10W1
olfactory receptor, family 10, subfamily W, member 1
chr4_-_159592996 0.11 ENST00000508457.1
C4orf46
chromosome 4 open reading frame 46
chr17_+_80009330 0.11 ENST00000580716.1
ENST00000583961.1
GPS1
G protein pathway suppressor 1
chr22_-_32058416 0.11 ENST00000439502.2
PISD
phosphatidylserine decarboxylase
chr1_-_94050668 0.11 ENST00000539242.1
BCAR3
breast cancer anti-estrogen resistance 3
chr19_-_15529790 0.10 ENST00000596195.1
ENST00000595067.1
ENST00000595465.2
ENST00000397410.5
ENST00000600247.1
AKAP8L
A kinase (PRKA) anchor protein 8-like
chr3_-_47555167 0.10 ENST00000296149.4
ELP6
elongator acetyltransferase complex subunit 6
chr3_+_9839335 0.10 ENST00000453882.1
ARPC4-TTLL3
ARPC4-TTLL3 readthrough
chr8_-_116681686 0.10 ENST00000519815.1
TRPS1
trichorhinophalangeal syndrome I
chr3_-_100565249 0.10 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr3_-_112218378 0.10 ENST00000334529.5
BTLA
B and T lymphocyte associated
chr9_-_130497565 0.10 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
TOR2A
torsin family 2, member A
chr9_-_127533582 0.10 ENST00000416460.2
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr6_-_137540477 0.10 ENST00000367735.2
ENST00000367739.4
ENST00000458076.1
ENST00000414770.1
IFNGR1
interferon gamma receptor 1
chr17_+_36908984 0.10 ENST00000225426.4
ENST00000579088.1
PSMB3
proteasome (prosome, macropain) subunit, beta type, 3
chr16_+_23194033 0.10 ENST00000300061.2
SCNN1G
sodium channel, non-voltage-gated 1, gamma subunit
chr18_+_32073253 0.10 ENST00000283365.9
ENST00000596745.1
ENST00000315456.6
DTNA
dystrobrevin, alpha
chr11_-_61062762 0.10 ENST00000335613.5
VWCE
von Willebrand factor C and EGF domains
chr11_+_92085262 0.09 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3
FAT atypical cadherin 3
chr18_+_60190226 0.09 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr12_-_122240792 0.09 ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
ENST00000541657.1
AC084018.1
RHOF
AC084018.1
ras homolog family member F (in filopodia)
chrY_-_20935572 0.09 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr16_-_18801643 0.09 ENST00000322989.4
ENST00000563390.1
RPS15A
ribosomal protein S15a
chr5_-_177210399 0.09 ENST00000510276.1
FAM153A
family with sequence similarity 153, member A
chr10_+_104005272 0.09 ENST00000369983.3
GBF1
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr14_-_54425475 0.09 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr22_+_26138108 0.09 ENST00000536101.1
ENST00000335473.7
ENST00000407587.2
MYO18B
myosin XVIIIB
chr6_-_42690312 0.09 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr9_+_125132803 0.09 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr10_-_50970322 0.09 ENST00000374103.4
OGDHL
oxoglutarate dehydrogenase-like
chr1_-_15850676 0.09 ENST00000440484.1
ENST00000333868.5
CASP9
caspase 9, apoptosis-related cysteine peptidase
chr15_-_58357932 0.08 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr22_+_24990746 0.08 ENST00000456869.1
ENST00000411974.1
GGT1
gamma-glutamyltransferase 1
chr6_-_25042231 0.08 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr13_+_27131887 0.08 ENST00000335327.5
WASF3
WAS protein family, member 3
chr6_+_168196210 0.08 ENST00000597278.1
AL009178.1
Uncharacterized protein; cDNA FLJ43200 fis, clone FEBRA2007793
chr5_+_173473662 0.08 ENST00000519717.1
NSG2
Neuron-specific protein family member 2
chr12_-_58240470 0.08 ENST00000548823.1
ENST00000398073.2
CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr16_-_23607598 0.08 ENST00000562133.1
ENST00000570319.1
ENST00000007516.3
NDUFAB1
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr15_-_90892669 0.08 ENST00000412799.2
GABARAPL3
GABA(A) receptors associated protein like 3, pseudogene
chr1_+_161719552 0.08 ENST00000367943.4
DUSP12
dual specificity phosphatase 12
chrY_+_20708557 0.08 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr6_-_90529418 0.08 ENST00000439638.1
ENST00000369393.3
ENST00000428876.1
MDN1
MDN1, midasin homolog (yeast)
chr7_-_99716952 0.08 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr17_-_48546324 0.08 ENST00000508540.1
CHAD
chondroadherin
chr18_+_29769978 0.08 ENST00000269202.6
ENST00000581447.1
MEP1B
meprin A, beta
chr12_-_66524482 0.08 ENST00000446587.2
ENST00000266604.2
LLPH
LLP homolog, long-term synaptic facilitation (Aplysia)
chr12_+_72079842 0.08 ENST00000266673.5
ENST00000550524.1
TMEM19
transmembrane protein 19
chr11_-_46408107 0.08 ENST00000433765.2
CHRM4
cholinergic receptor, muscarinic 4
chr22_-_29075853 0.08 ENST00000397906.2
TTC28
tetratricopeptide repeat domain 28
chr19_+_6361440 0.07 ENST00000245816.4
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr15_-_75249793 0.07 ENST00000322177.5
RPP25
ribonuclease P/MRP 25kDa subunit
chr16_-_28857677 0.07 ENST00000313511.3
TUFM
Tu translation elongation factor, mitochondrial
chr19_+_36120009 0.07 ENST00000589871.1
RBM42
RNA binding motif protein 42
chr15_-_31453359 0.07 ENST00000542188.1
TRPM1
transient receptor potential cation channel, subfamily M, member 1
chr11_+_73359936 0.07 ENST00000542389.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr6_+_37321823 0.07 ENST00000487950.1
ENST00000469731.1
RNF8
ring finger protein 8, E3 ubiquitin protein ligase
chr9_-_127533519 0.07 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr19_-_4400415 0.07 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1
SH3-domain GRB2-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.6 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.6 GO:0019046 release from viral latency(GO:0019046)
0.1 0.4 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.5 GO:0072255 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.9 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 0.4 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:0090427 activation of meiosis(GO:0090427)
0.1 0.2 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.3 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.6 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0051413 response to cortisone(GO:0051413)
0.0 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.0 0.2 GO:2000053 negative regulation of B cell differentiation(GO:0045578) negative regulation of non-canonical Wnt signaling pathway(GO:2000051) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 1.4 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1900154 regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.2 GO:0051563 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.8 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.5 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0071893 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.5 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.0 GO:1902573 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.0 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.0 0.0 GO:0045399 response to molecule of fungal origin(GO:0002238) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) beta selection(GO:0043366) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045423) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425) cellular response to molecule of fungal origin(GO:0071226)
0.0 0.1 GO:0036369 transcription factor catabolic process(GO:0036369)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.0 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.0 0.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.2 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 1.4 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253) gamma-secretase complex(GO:0070765)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.0 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.9 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 0.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.2 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.4 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.4 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.3 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.6 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.2 GO:0016936 galactoside binding(GO:0016936)
0.0 0.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0008430 selenium binding(GO:0008430) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.6 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.0 GO:0001855 complement component C4b binding(GO:0001855)
0.0 0.1 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0004312 fatty acid synthase activity(GO:0004312)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle