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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for PRDM4
Z-value: 1.07
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Transcription factors associated with PRDM4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PRDM4 | hg19_v2_chr12_-_108154925_108154945 | -0.63 | 3.7e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of PRDM4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 2.0 | GO:0061580 | colon epithelial cell migration(GO:0061580) |
| 0.0 | 1.2 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.2 | 0.8 | GO:1990936 | metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936) |
| 0.0 | 0.8 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.0 | 0.7 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.2 | 0.6 | GO:0036060 | filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060) |
| 0.1 | 0.6 | GO:0030578 | PML body organization(GO:0030578) |
| 0.0 | 0.6 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
| 0.1 | 0.4 | GO:0035425 | autocrine signaling(GO:0035425) |
| 0.1 | 0.4 | GO:0042357 | thiamine diphosphate metabolic process(GO:0042357) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.1 | 0.6 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.0 | 0.6 | GO:0032426 | stereocilium tip(GO:0032426) |
| 0.0 | 0.4 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.3 | GO:0089701 | U2AF(GO:0089701) |
| 0.0 | 0.2 | GO:0042587 | glycogen granule(GO:0042587) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 2.0 | GO:0003943 | N-acetylgalactosamine-4-sulfatase activity(GO:0003943) |
| 0.0 | 1.9 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.1 | 1.2 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.0 | 1.1 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.0 | 0.8 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
| 0.0 | 0.8 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 0.0 | 0.6 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 0.5 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
| 0.1 | 0.4 | GO:0050333 | thiamin-triphosphatase activity(GO:0050333) |
| 0.0 | 0.4 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 0.8 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 0.6 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.4 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.0 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 0.0 | 1.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.5 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |