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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for POU6F1

Z-value: 0.45

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Transcription factors associated with POU6F1

Gene Symbol Gene ID Gene Info
POU6F1
ENSG00000184271.11 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU6F1hg19_v2_chr12_-_51611477_516116120.336.7e-01Click!

Activity profile of POU6F1 motif

Sorted Z-values of POU6F1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_102513950 0.53 ENST00000378128.3
ENST00000327680.2
ENST00000541394.1
ENST00000543784.1
PARPBP
PARP1 binding protein
chr2_+_102721023 0.49 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr13_+_98612446 0.43 ENST00000496368.1
ENST00000421861.2
ENST00000357602.3
IPO5
importin 5
chr5_+_162864575 0.39 ENST00000512163.1
ENST00000393929.1
ENST00000340828.2
ENST00000511683.2
ENST00000510097.1
ENST00000511490.2
ENST00000510664.1
CCNG1
cyclin G1
chr1_-_197115818 0.35 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr12_+_49297899 0.34 ENST00000552942.1
ENST00000320516.4
CCDC65
coiled-coil domain containing 65
chrX_+_43515467 0.34 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr13_-_52027134 0.25 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr9_+_26746951 0.21 ENST00000523363.1
RP11-18A15.1
RP11-18A15.1
chr1_+_225117350 0.21 ENST00000413949.2
ENST00000430092.1
ENST00000366850.3
ENST00000400952.3
ENST00000366849.1
DNAH14
dynein, axonemal, heavy chain 14
chr8_-_146176199 0.21 ENST00000532351.1
ENST00000276816.4
ENST00000394909.2
ZNF16
zinc finger protein 16
chr15_+_59279851 0.20 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111
ring finger protein 111
chr17_-_25568687 0.20 ENST00000581944.1
RP11-663N22.1
RP11-663N22.1
chr11_+_85339623 0.19 ENST00000358867.6
ENST00000534341.1
ENST00000393375.1
ENST00000531274.1
TMEM126B
transmembrane protein 126B
chr19_+_10959043 0.19 ENST00000397820.4
C19orf38
chromosome 19 open reading frame 38
chr20_+_58515417 0.19 ENST00000360816.3
FAM217B
family with sequence similarity 217, member B
chr2_+_242289502 0.19 ENST00000451310.1
SEPT2
septin 2
chr7_-_83824449 0.19 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr18_+_52495426 0.18 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chr1_+_225140372 0.18 ENST00000366848.1
ENST00000439375.2
DNAH14
dynein, axonemal, heavy chain 14
chr17_+_73539339 0.17 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr20_+_5987890 0.17 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr5_+_115177178 0.16 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr6_-_47009996 0.16 ENST00000371243.2
GPR110
G protein-coupled receptor 110
chr12_-_57443886 0.15 ENST00000300119.3
MYO1A
myosin IA
chr15_-_85259360 0.15 ENST00000559729.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr22_+_31518938 0.15 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr12_+_102514019 0.15 ENST00000537257.1
ENST00000358383.5
ENST00000392911.2
PARPBP
PARP1 binding protein
chr15_-_44828838 0.15 ENST00000560750.1
EIF3J-AS1
EIF3J antisense RNA 1 (head to head)
chr14_-_70883708 0.15 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr10_+_97803151 0.14 ENST00000403870.3
ENST00000265992.5
ENST00000465148.2
ENST00000534974.1
CCNJ
cyclin J
chrY_+_14958970 0.13 ENST00000453031.1
USP9Y
ubiquitin specific peptidase 9, Y-linked
chr1_-_243326612 0.13 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr7_+_141490017 0.13 ENST00000247883.4
TAS2R5
taste receptor, type 2, member 5
chr12_+_49297887 0.12 ENST00000266984.5
CCDC65
coiled-coil domain containing 65
chr15_-_85259384 0.11 ENST00000455959.3
SEC11A
SEC11 homolog A (S. cerevisiae)
chr21_-_34915123 0.11 ENST00000438059.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr16_-_58718638 0.11 ENST00000562397.1
ENST00000564010.1
ENST00000570214.1
ENST00000563196.1
SLC38A7
solute carrier family 38, member 7
chr2_-_85828867 0.10 ENST00000425160.1
TMEM150A
transmembrane protein 150A
chr1_-_161008697 0.09 ENST00000318289.10
ENST00000368023.3
ENST00000368024.1
ENST00000423014.2
TSTD1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr3_-_48659193 0.09 ENST00000330862.3
TMEM89
transmembrane protein 89
chr6_-_111136513 0.09 ENST00000368911.3
CDK19
cyclin-dependent kinase 19
chr6_-_111804905 0.09 ENST00000358835.3
ENST00000435970.1
REV3L
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
chrX_-_100129128 0.08 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr11_-_93583697 0.08 ENST00000409977.1
VSTM5
V-set and transmembrane domain containing 5
chr1_-_151431909 0.08 ENST00000361398.3
ENST00000271715.2
POGZ
pogo transposable element with ZNF domain
chr7_-_77427676 0.08 ENST00000257663.3
TMEM60
transmembrane protein 60
chr2_+_191045562 0.08 ENST00000340623.4
C2orf88
chromosome 2 open reading frame 88
chr15_-_31283618 0.08 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr15_-_85259294 0.07 ENST00000558217.1
ENST00000558196.1
ENST00000558134.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chr15_-_85259330 0.07 ENST00000560266.1
SEC11A
SEC11 homolog A (S. cerevisiae)
chrX_+_102024075 0.06 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
LINC00630
long intergenic non-protein coding RNA 630
chr1_-_151431647 0.06 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr20_-_58515344 0.06 ENST00000370996.3
PPP1R3D
protein phosphatase 1, regulatory subunit 3D
chrX_-_122756660 0.06 ENST00000441692.1
THOC2
THO complex 2
chr14_+_24970800 0.06 ENST00000555109.1
RP11-80A15.1
Uncharacterized protein
chr11_-_65381643 0.06 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr12_-_7596735 0.05 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr6_-_26235206 0.05 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr18_+_9475001 0.05 ENST00000019317.4
RALBP1
ralA binding protein 1
chr9_+_128509624 0.05 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr7_+_48494660 0.05 ENST00000411975.1
ENST00000544596.1
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr6_-_138539627 0.05 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr10_-_94257512 0.05 ENST00000371581.5
IDE
insulin-degrading enzyme
chr5_+_67586465 0.05 ENST00000336483.5
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_-_43904235 0.05 ENST00000356053.3
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr6_-_110501126 0.05 ENST00000368938.1
WASF1
WAS protein family, member 1
chrX_+_119737806 0.04 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr11_+_118398178 0.04 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr16_+_19422035 0.04 ENST00000381414.4
ENST00000396229.2
TMC5
transmembrane channel-like 5
chr1_+_176432298 0.04 ENST00000367661.3
ENST00000367662.3
PAPPA2
pappalysin 2
chr6_-_111136299 0.04 ENST00000457688.1
CDK19
cyclin-dependent kinase 19
chr15_+_45028719 0.04 ENST00000560442.1
ENST00000558329.1
ENST00000561043.1
TRIM69
tripartite motif containing 69
chr6_-_110501200 0.03 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WASF1
WAS protein family, member 1
chr1_-_153538292 0.03 ENST00000497140.1
ENST00000368708.3
S100A2
S100 calcium binding protein A2
chr17_-_39165366 0.03 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr17_-_40337470 0.02 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr9_+_103790991 0.02 ENST00000374874.3
LPPR1
Lipid phosphate phosphatase-related protein type 1
chr2_+_128403720 0.02 ENST00000272644.3
GPR17
G protein-coupled receptor 17
chr4_-_83812157 0.02 ENST00000513323.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr1_-_151431674 0.02 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr2_+_128403439 0.02 ENST00000544369.1
GPR17
G protein-coupled receptor 17
chr20_-_50418972 0.02 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr4_+_40201954 0.01 ENST00000511121.1
RHOH
ras homolog family member H
chr12_-_95397442 0.01 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr18_-_73967160 0.01 ENST00000579714.1
RP11-94B19.7
RP11-94B19.7
chr19_+_42817527 0.01 ENST00000598766.1
TMEM145
transmembrane protein 145
chr7_-_38407770 0.01 ENST00000390348.2
TRGV1
T cell receptor gamma variable 1 (non-functional)
chr22_-_28490123 0.01 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr9_+_131644398 0.01 ENST00000372599.3
LRRC8A
leucine rich repeat containing 8 family, member A
chr2_-_179516225 0.01 ENST00000446966.1
ENST00000426232.1
TTN
titin
chr1_+_222913009 0.00 ENST00000456298.1
FAM177B
family with sequence similarity 177, member B
chr6_+_110501344 0.00 ENST00000368932.1
CDC40
cell division cycle 40
chr9_-_4666337 0.00 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like

Network of associatons between targets according to the STRING database.

First level regulatory network of POU6F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.5 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.3 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.0 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.2 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:0004641 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.4 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG