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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for POU2F2_POU3F1

Z-value: 1.29

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Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
POU2F2
ENSG00000028277.16 POU class 2 homeobox 2
POU3F1
ENSG00000185668.5 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636617_42636632-0.732.7e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_38171681 2.27 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
CSF3
colony stimulating factor 3 (granulocyte)
chr17_+_38171614 1.95 ENST00000583218.1
ENST00000394149.3
CSF3
colony stimulating factor 3 (granulocyte)
chr6_+_27114861 1.27 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr6_-_26124138 1.24 ENST00000314332.5
ENST00000396984.1
HIST1H2BC
histone cluster 1, H2bc
chr6_-_26043885 1.03 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr6_-_27860956 1.03 ENST00000359611.2
HIST1H2AM
histone cluster 1, H2am
chr11_-_129872672 1.02 ENST00000531431.1
ENST00000527581.1
PRDM10
PR domain containing 10
chr7_-_100183742 0.94 ENST00000310300.6
LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr9_-_35658007 0.90 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr6_+_26183958 0.90 ENST00000356530.3
HIST1H2BE
histone cluster 1, H2be
chr6_+_31588478 0.85 ENST00000376007.4
ENST00000376033.2
PRRC2A
proline-rich coiled-coil 2A
chr12_+_113344582 0.85 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344811 0.82 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344755 0.76 ENST00000550883.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr5_+_158527485 0.76 ENST00000517335.1
RP11-175K6.1
RP11-175K6.1
chr17_+_62461569 0.68 ENST00000603557.1
ENST00000605096.1
MILR1
mast cell immunoglobulin-like receptor 1
chr19_-_17516449 0.68 ENST00000252593.6
BST2
bone marrow stromal cell antigen 2
chr10_+_106113515 0.68 ENST00000369704.3
ENST00000312902.5
CCDC147
coiled-coil domain containing 147
chr14_+_65007177 0.67 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chr22_+_43011247 0.65 ENST00000602478.1
RNU12
RNA, U12 small nuclear
chr7_+_26438187 0.64 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
AC004540.5
chr19_-_44171817 0.63 ENST00000593714.1
PLAUR
plasminogen activator, urokinase receptor
chr16_-_88752889 0.61 ENST00000332281.5
SNAI3
snail family zinc finger 3
chr11_-_62369291 0.60 ENST00000278823.2
MTA2
metastasis associated 1 family, member 2
chrX_+_12993202 0.60 ENST00000451311.2
ENST00000380636.1
TMSB4X
thymosin beta 4, X-linked
chr1_+_225600404 0.60 ENST00000366845.2
AC092811.1
AC092811.1
chr17_-_19015945 0.57 ENST00000573866.2
SNORD3D
small nucleolar RNA, C/D box 3D
chrX_+_12993336 0.54 ENST00000380635.1
TMSB4X
thymosin beta 4, X-linked
chr19_-_1132207 0.53 ENST00000438103.2
SBNO2
strawberry notch homolog 2 (Drosophila)
chr5_-_141030943 0.53 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr12_+_14369524 0.52 ENST00000538329.1
RP11-134N1.2
RP11-134N1.2
chr12_+_7053172 0.51 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr12_+_7053228 0.51 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr9_-_84303269 0.51 ENST00000418319.1
TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr19_+_29493456 0.50 ENST00000591143.1
ENST00000592653.1
CTD-2081K17.2
CTD-2081K17.2
chr12_-_62653903 0.50 ENST00000552075.1
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr8_-_16859690 0.50 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr15_+_67458357 0.49 ENST00000537194.2
SMAD3
SMAD family member 3
chr17_+_19091325 0.49 ENST00000584923.1
SNORD3A
small nucleolar RNA, C/D box 3A
chr12_-_58212487 0.47 ENST00000549994.1
AVIL
advillin
chr3_-_71632894 0.47 ENST00000493089.1
FOXP1
forkhead box P1
chr2_+_66918558 0.47 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr14_-_106573756 0.46 ENST00000390601.2
IGHV3-11
immunoglobulin heavy variable 3-11 (gene/pseudogene)
chr12_+_7052974 0.45 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr11_+_64085560 0.43 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
PRDX5
peroxiredoxin 5
chr10_-_10504285 0.43 ENST00000602311.1
RP11-271F18.4
RP11-271F18.4
chr15_+_65337708 0.43 ENST00000334287.2
SLC51B
solute carrier family 51, beta subunit
chr17_+_40118805 0.43 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_+_17575584 0.42 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr7_-_50860565 0.42 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chr7_-_27153454 0.42 ENST00000522456.1
HOXA3
homeobox A3
chr19_-_50143452 0.42 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr12_-_7245125 0.42 ENST00000542285.1
ENST00000540610.1
C1R
complement component 1, r subcomponent
chr12_-_7245018 0.41 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr19_+_39903185 0.41 ENST00000409794.3
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr11_+_69455855 0.39 ENST00000227507.2
ENST00000536559.1
CCND1
cyclin D1
chr19_-_40931891 0.39 ENST00000357949.4
SERTAD1
SERTA domain containing 1
chr9_-_32526299 0.38 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_-_41742697 0.37 ENST00000242208.4
INHBA
inhibin, beta A
chr4_-_99578789 0.37 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr11_-_34379546 0.37 ENST00000435224.2
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr17_+_40118773 0.37 ENST00000472031.1
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_+_43086018 0.36 ENST00000550177.1
RP11-25I15.3
RP11-25I15.3
chr5_+_36608422 0.36 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr3_+_197464046 0.35 ENST00000428738.1
FYTTD1
forty-two-three domain containing 1
chr12_+_122064398 0.35 ENST00000330079.7
ORAI1
ORAI calcium release-activated calcium modulator 1
chr19_-_893200 0.34 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
MED16
mediator complex subunit 16
chr19_-_18508396 0.34 ENST00000595840.1
ENST00000339007.3
LRRC25
leucine rich repeat containing 25
chr5_+_73109339 0.33 ENST00000296799.4
ARHGEF28
Rho guanine nucleotide exchange factor (GEF) 28
chr12_-_7245152 0.33 ENST00000542220.2
C1R
complement component 1, r subcomponent
chr17_+_40118759 0.33 ENST00000393892.3
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_-_7245080 0.33 ENST00000541042.1
ENST00000540242.1
C1R
complement component 1, r subcomponent
chr22_+_44319648 0.32 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr6_+_26217159 0.32 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr3_-_33686925 0.32 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr2_-_239148599 0.31 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chr5_-_178017355 0.31 ENST00000390654.3
COL23A1
collagen, type XXIII, alpha 1
chr19_-_3971050 0.31 ENST00000545797.2
ENST00000596311.1
DAPK3
death-associated protein kinase 3
chr16_-_73082274 0.31 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr6_+_43139037 0.31 ENST00000265354.4
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr3_-_48594248 0.30 ENST00000545984.1
ENST00000232375.3
ENST00000416568.1
ENST00000383734.2
ENST00000541519.1
ENST00000412035.1
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr2_+_145780725 0.30 ENST00000451478.1
TEX41
testis expressed 41 (non-protein coding)
chr7_+_129932974 0.30 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4
carboxypeptidase A4
chr16_+_56691606 0.30 ENST00000334350.6
MT1F
metallothionein 1F
chr11_-_18258342 0.30 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr6_-_11779403 0.29 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chrX_-_55020511 0.29 ENST00000375006.3
ENST00000374992.2
PFKFB1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr15_-_41166414 0.29 ENST00000220507.4
RHOV
ras homolog family member V
chr1_+_32538492 0.28 ENST00000336294.5
TMEM39B
transmembrane protein 39B
chr1_+_24018269 0.28 ENST00000374550.3
RPL11
ribosomal protein L11
chr19_+_3572758 0.28 ENST00000416526.1
HMG20B
high mobility group 20B
chr19_-_45982076 0.28 ENST00000423698.2
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr8_+_102064237 0.28 ENST00000514926.1
RP11-302J23.1
RP11-302J23.1
chr17_-_73775839 0.28 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr5_-_175965008 0.27 ENST00000537487.1
RNF44
ring finger protein 44
chr1_-_190446759 0.27 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr10_+_24528108 0.27 ENST00000438429.1
KIAA1217
KIAA1217
chr1_-_149859466 0.27 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr7_-_27219849 0.27 ENST00000396344.4
HOXA10
homeobox A10
chr11_-_115375107 0.26 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr7_-_112727774 0.26 ENST00000297146.3
ENST00000501255.2
GPR85
G protein-coupled receptor 85
chr19_-_50168962 0.25 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3
interferon regulatory factor 3
chr19_-_50169064 0.25 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3
interferon regulatory factor 3
chr6_-_11779014 0.25 ENST00000229583.5
ADTRP
androgen-dependent TFPI-regulating protein
chr7_-_93520259 0.25 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr14_-_106622419 0.25 ENST00000390604.2
IGHV3-16
immunoglobulin heavy variable 3-16 (non-functional)
chr11_-_62358972 0.25 ENST00000278279.3
TUT1
terminal uridylyl transferase 1, U6 snRNA-specific
chr7_-_93520191 0.25 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr12_+_123944070 0.24 ENST00000412157.2
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr12_-_31479107 0.24 ENST00000542983.1
FAM60A
family with sequence similarity 60, member A
chr7_+_90338712 0.24 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr14_-_106845789 0.24 ENST00000390617.2
IGHV3-35
immunoglobulin heavy variable 3-35 (non-functional)
chr14_-_24615523 0.24 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr6_+_34204642 0.24 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr8_-_57123815 0.23 ENST00000316981.3
ENST00000423799.2
ENST00000429357.2
PLAG1
pleiomorphic adenoma gene 1
chr19_-_1021113 0.23 ENST00000333175.5
ENST00000356663.3
TMEM259
transmembrane protein 259
chr11_-_64085533 0.23 ENST00000544844.1
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr17_-_7580752 0.23 ENST00000508793.1
TP53
tumor protein p53
chr9_+_35658262 0.23 ENST00000378407.3
ENST00000378406.1
ENST00000426546.2
ENST00000327351.2
ENST00000421582.2
CCDC107
coiled-coil domain containing 107
chr2_+_207804278 0.22 ENST00000272852.3
CPO
carboxypeptidase O
chr1_-_209792111 0.22 ENST00000455193.1
LAMB3
laminin, beta 3
chr2_+_16080659 0.22 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr6_-_34113856 0.22 ENST00000538487.2
GRM4
glutamate receptor, metabotropic 4
chr12_+_122064673 0.22 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr6_-_33679452 0.22 ENST00000374231.4
ENST00000607484.1
ENST00000374214.3
UQCC2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr17_+_72426891 0.22 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_-_75917569 0.21 ENST00000322563.3
WNT11
wingless-type MMTV integration site family, member 11
chr21_-_36260980 0.21 ENST00000344691.4
ENST00000358356.5
RUNX1
runt-related transcription factor 1
chr12_-_16760195 0.21 ENST00000546281.1
ENST00000537757.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_-_106692191 0.21 ENST00000390607.2
IGHV3-21
immunoglobulin heavy variable 3-21
chr19_+_41305085 0.20 ENST00000303961.4
EGLN2
egl-9 family hypoxia-inducible factor 2
chr2_+_220143989 0.20 ENST00000336576.5
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr17_-_73127778 0.20 ENST00000578407.1
NT5C
5', 3'-nucleotidase, cytosolic
chr7_+_116451100 0.20 ENST00000464223.1
ENST00000484325.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_+_220144052 0.20 ENST00000425450.1
ENST00000392086.4
ENST00000421532.1
DNAJB2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr15_+_84115868 0.20 ENST00000427482.2
SH3GL3
SH3-domain GRB2-like 3
chr18_-_52989525 0.20 ENST00000457482.3
TCF4
transcription factor 4
chr14_-_106994333 0.20 ENST00000390624.2
IGHV3-48
immunoglobulin heavy variable 3-48
chr16_+_3019552 0.20 ENST00000572687.1
PAQR4
progestin and adipoQ receptor family member IV
chr3_-_126327398 0.20 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr11_-_64084959 0.20 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
TRMT112
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr2_-_207082748 0.20 ENST00000407325.2
ENST00000411719.1
GPR1
G protein-coupled receptor 1
chr20_-_60982330 0.19 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr2_+_201173667 0.19 ENST00000409755.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr11_+_537494 0.19 ENST00000270115.7
LRRC56
leucine rich repeat containing 56
chr4_-_186733363 0.19 ENST00000393523.2
ENST00000393528.3
ENST00000449407.2
SORBS2
sorbin and SH3 domain containing 2
chr1_-_149858227 0.19 ENST00000369155.2
HIST2H2BE
histone cluster 2, H2be
chr2_-_225811747 0.18 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr16_+_3019246 0.18 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr14_-_106552755 0.18 ENST00000390600.2
IGHV3-9
immunoglobulin heavy variable 3-9
chr19_-_8373173 0.18 ENST00000537716.2
ENST00000301458.5
CD320
CD320 molecule
chr12_+_93096619 0.18 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr14_-_106586656 0.18 ENST00000390602.2
IGHV3-13
immunoglobulin heavy variable 3-13
chr12_+_132312931 0.18 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr7_-_44122063 0.18 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
POLM
polymerase (DNA directed), mu
chr9_+_35658377 0.18 ENST00000378409.3
CCDC107
coiled-coil domain containing 107
chr17_-_36105009 0.18 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1B
HNF1 homeobox B
chr22_-_43010928 0.18 ENST00000348657.2
ENST00000252115.5
POLDIP3
polymerase (DNA-directed), delta interacting protein 3
chr19_+_11466062 0.18 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr16_+_3019309 0.18 ENST00000576565.1
PAQR4
progestin and adipoQ receptor family member IV
chr17_+_20059302 0.18 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr1_-_149814478 0.17 ENST00000369161.3
HIST2H2AA3
histone cluster 2, H2aa3
chr16_-_55909272 0.17 ENST00000319165.9
CES5A
carboxylesterase 5A
chr19_+_30719410 0.17 ENST00000585628.1
ENST00000591488.1
ZNF536
zinc finger protein 536
chr4_-_47983519 0.17 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr12_+_93096759 0.17 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr16_-_55909255 0.17 ENST00000290567.9
CES5A
carboxylesterase 5A
chr17_+_20059358 0.17 ENST00000536879.1
ENST00000395522.2
ENST00000395525.3
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr19_+_3572925 0.17 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
HMG20B
high mobility group 20B
chr4_-_71532601 0.17 ENST00000510614.1
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr2_-_158182410 0.17 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr17_-_48072574 0.17 ENST00000434704.2
DLX3
distal-less homeobox 3
chr16_-_55909211 0.17 ENST00000520435.1
CES5A
carboxylesterase 5A
chr1_-_23886285 0.17 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr19_+_11466167 0.17 ENST00000591608.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr3_-_107777208 0.16 ENST00000398258.3
CD47
CD47 molecule
chr17_-_36358166 0.16 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chrX_-_11369656 0.16 ENST00000413512.3
ARHGAP6
Rho GTPase activating protein 6
chr5_-_81574160 0.16 ENST00000510210.1
ENST00000512493.1
ENST00000507980.1
ENST00000511844.1
ENST00000510019.1
RPS23
ribosomal protein S23
chr19_-_19281054 0.16 ENST00000424583.2
ENST00000410050.1
ENST00000409224.1
ENST00000409447.2
MEF2B
myocyte enhancer factor 2B
chr14_+_79745746 0.16 ENST00000281127.7
NRXN3
neurexin 3
chr6_+_116691001 0.16 ENST00000537543.1
DSE
dermatan sulfate epimerase
chr12_+_130646999 0.16 ENST00000539839.1
ENST00000229030.4
FZD10
frizzled family receptor 10
chr7_-_27219632 0.16 ENST00000470747.4
RP1-170O19.20
Uncharacterized protein
chr14_-_107199464 0.16 ENST00000433072.2
IGHV3-72
immunoglobulin heavy variable 3-72
chr9_-_127533582 0.16 ENST00000416460.2
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr1_-_2458026 0.16 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr1_+_206579736 0.15 ENST00000439126.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr15_-_45406385 0.15 ENST00000389039.6
DUOX2
dual oxidase 2
chr17_-_47841485 0.15 ENST00000506156.1
ENST00000240364.2
FAM117A
family with sequence similarity 117, member A
chr2_-_8464760 0.15 ENST00000430192.1
LINC00299
long intergenic non-protein coding RNA 299
chr1_-_110284384 0.15 ENST00000540225.1
GSTM3
glutathione S-transferase mu 3 (brain)
chr15_-_45406348 0.14 ENST00000603300.1
DUOX2
dual oxidase 2
chr14_-_106518922 0.14 ENST00000390598.2
IGHV3-7
immunoglobulin heavy variable 3-7
chr4_-_71532207 0.14 ENST00000543780.1
ENST00000391614.3
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_-_106926724 0.14 ENST00000434710.1
IGHV3-43
immunoglobulin heavy variable 3-43
chr11_-_66112555 0.14 ENST00000425825.2
ENST00000359957.3
BRMS1
breast cancer metastasis suppressor 1
chr4_+_26322185 0.14 ENST00000361572.6
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr1_-_154832316 0.14 ENST00000361147.4
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr19_-_50168861 0.14 ENST00000596756.1
IRF3
interferon regulatory factor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.2 GO:0030223 neutrophil differentiation(GO:0030223)
0.4 1.5 GO:0036343 psychomotor behavior(GO:0036343)
0.2 0.7 GO:0002731 negative regulation of dendritic cell cytokine production(GO:0002731)
0.1 1.1 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.1 0.5 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.4 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.3 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.1 0.4 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.9 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.2 GO:0071895 odontoblast differentiation(GO:0071895)
0.1 0.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.6 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.1 0.3 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.1 0.5 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.5 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.1 0.2 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.1 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.6 GO:0071888 macrophage apoptotic process(GO:0071888)
0.1 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.4 GO:0010159 specification of organ position(GO:0010159)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.3 GO:0042335 cuticle development(GO:0042335) hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:0070668 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.2 GO:0090402 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.7 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.4 GO:0070779 gamma-aminobutyric acid biosynthetic process(GO:0009449) D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.9 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 3.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.4 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.7 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.4 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.6 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.4 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.3 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 2.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.1 GO:0045872 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.2 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:1905069 allantois development(GO:1905069)
0.0 0.2 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.0 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.2 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) positive regulation of mitochondrial translation(GO:0070131) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 1.2 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.1 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:0035799 ureter maturation(GO:0035799)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.4 GO:0046135 pyrimidine nucleoside catabolic process(GO:0046135)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.1 GO:0010157 response to chlorate(GO:0010157)
0.0 0.2 GO:0060065 uterus development(GO:0060065)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.3 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.4 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.4 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.4 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 1.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 0.7 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.6 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.7 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.0 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.2 2.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.6 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.1 0.3 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.3 GO:0010736 serum response element binding(GO:0010736)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.4 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.2 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.3 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.4 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 4.5 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.2 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0042923 neuropeptide binding(GO:0042923)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 5.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 2.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.6 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME AMYLOIDS Genes involved in Amyloids