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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PDX1

Z-value: 1.33

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Transcription factors associated with PDX1

Gene Symbol Gene ID Gene Info
PDX1
ENSG00000139515.5 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PDX1hg19_v2_chr13_+_28494130_28494168-0.693.1e-01Click!

Activity profile of PDX1 motif

Sorted Z-values of PDX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_92777606 1.60 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr11_+_4510109 1.30 ENST00000307632.3
OR52K1
olfactory receptor, family 52, subfamily K, member 1
chr8_-_42234745 1.27 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chr7_+_37723336 1.22 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr1_+_158979792 1.09 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr15_+_63188009 1.08 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr2_+_66918558 0.97 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr7_+_129015484 0.89 ENST00000490911.1
AHCYL2
adenosylhomocysteinase-like 2
chr14_+_61654271 0.87 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
PRKCH
protein kinase C, eta
chr14_-_77889860 0.86 ENST00000555603.1
NOXRED1
NADP-dependent oxidoreductase domain containing 1
chr2_+_228736335 0.86 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr6_-_31107127 0.83 ENST00000259845.4
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr4_-_41884620 0.83 ENST00000504870.1
LINC00682
long intergenic non-protein coding RNA 682
chr17_-_71223839 0.79 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr15_+_91416092 0.74 ENST00000559353.1
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_-_108248169 0.74 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr4_+_169013666 0.73 ENST00000359299.3
ANXA10
annexin A10
chr20_+_45947246 0.69 ENST00000599904.1
AL031666.2
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr11_+_35222629 0.68 ENST00000526553.1
CD44
CD44 molecule (Indian blood group)
chr3_-_121740969 0.67 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chrX_-_106146547 0.66 ENST00000276173.4
ENST00000411805.1
RIPPLY1
ripply transcriptional repressor 1
chr11_-_8290263 0.66 ENST00000428101.2
LMO1
LIM domain only 1 (rhombotin 1)
chr11_+_110001723 0.63 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr6_+_126221034 0.62 ENST00000433571.1
NCOA7
nuclear receptor coactivator 7
chr17_-_46690839 0.61 ENST00000498634.2
HOXB8
homeobox B8
chr17_+_72427477 0.61 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_-_190927447 0.60 ENST00000260950.4
MSTN
myostatin
chr12_-_54813229 0.60 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr5_-_141249154 0.57 ENST00000357517.5
ENST00000536585.1
PCDH1
protocadherin 1
chr15_+_80351910 0.56 ENST00000261749.6
ENST00000561060.1
ZFAND6
zinc finger, AN1-type domain 6
chr1_-_190446759 0.55 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr11_-_8285405 0.54 ENST00000335790.3
ENST00000534484.1
LMO1
LIM domain only 1 (rhombotin 1)
chr13_-_46716969 0.54 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr18_-_47792851 0.53 ENST00000398545.4
CCDC11
coiled-coil domain containing 11
chr20_+_60174827 0.52 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr10_-_21186144 0.52 ENST00000377119.1
NEBL
nebulette
chr11_-_115375107 0.51 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr7_+_129015671 0.48 ENST00000466993.1
AHCYL2
adenosylhomocysteinase-like 2
chrX_+_591524 0.44 ENST00000554971.1
ENST00000381575.1
SHOX
short stature homeobox
chr2_+_234959376 0.44 ENST00000425558.1
SPP2
secreted phosphoprotein 2, 24kDa
chr17_-_8301132 0.44 ENST00000399398.2
RNF222
ring finger protein 222
chr2_+_87769459 0.44 ENST00000414030.1
ENST00000437561.1
LINC00152
long intergenic non-protein coding RNA 152
chr15_+_62853562 0.43 ENST00000561311.1
TLN2
talin 2
chr5_+_135394840 0.43 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr1_+_107683644 0.43 ENST00000370067.1
NTNG1
netrin G1
chrX_+_10126488 0.42 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr19_-_7968427 0.42 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr8_+_77593448 0.42 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr2_+_45168875 0.40 ENST00000260653.3
SIX3
SIX homeobox 3
chr1_+_66796401 0.40 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_-_23633720 0.39 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr21_+_30673091 0.39 ENST00000447177.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr18_+_3447572 0.39 ENST00000548489.2
TGIF1
TGFB-induced factor homeobox 1
chr2_-_145277569 0.39 ENST00000303660.4
ZEB2
zinc finger E-box binding homeobox 2
chr12_-_109221160 0.39 ENST00000326470.5
SSH1
slingshot protein phosphatase 1
chr15_-_55562479 0.38 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr17_-_18430160 0.38 ENST00000392176.3
FAM106A
family with sequence similarity 106, member A
chr19_-_7697857 0.38 ENST00000598935.1
PCP2
Purkinje cell protein 2
chr12_+_42725554 0.37 ENST00000546750.1
ENST00000547847.1
PPHLN1
periphilin 1
chrX_-_106243294 0.37 ENST00000255495.7
MORC4
MORC family CW-type zinc finger 4
chr12_+_64798826 0.37 ENST00000540203.1
XPOT
exportin, tRNA
chr11_+_65554493 0.37 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr4_-_70518941 0.36 ENST00000286604.4
ENST00000505512.1
ENST00000514019.1
UGT2A1
UGT2A1
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr4_+_30721968 0.35 ENST00000361762.2
PCDH7
protocadherin 7
chrX_-_110655306 0.35 ENST00000371993.2
DCX
doublecortin
chr7_-_33102338 0.34 ENST00000610140.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr10_+_24738355 0.34 ENST00000307544.6
KIAA1217
KIAA1217
chr15_-_100882191 0.34 ENST00000268070.4
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr14_-_36988882 0.34 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr20_-_56286479 0.33 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr1_+_198608146 0.33 ENST00000367376.2
ENST00000352140.3
ENST00000594404.1
ENST00000598951.1
ENST00000530727.1
ENST00000442510.2
ENST00000367367.4
ENST00000348564.6
ENST00000367364.1
ENST00000413409.2
PTPRC
protein tyrosine phosphatase, receptor type, C
chr7_-_33102399 0.33 ENST00000242210.7
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr1_+_19967014 0.33 ENST00000428975.1
NBL1
neuroblastoma 1, DAN family BMP antagonist
chr14_-_61116168 0.31 ENST00000247182.6
SIX1
SIX homeobox 1
chr6_+_34204642 0.31 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1
high mobility group AT-hook 1
chr5_+_174151536 0.30 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr17_-_38928414 0.30 ENST00000335552.4
KRT26
keratin 26
chr7_-_99716952 0.30 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr9_-_117267717 0.29 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr7_-_99717463 0.29 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr8_+_9953214 0.29 ENST00000382490.5
MSRA
methionine sulfoxide reductase A
chr19_+_11071546 0.29 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr1_-_94147385 0.28 ENST00000260502.6
BCAR3
breast cancer anti-estrogen resistance 3
chr12_-_56321649 0.27 ENST00000454792.2
ENST00000408946.2
WIBG
within bgcn homolog (Drosophila)
chr20_-_50418947 0.27 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr9_-_16728161 0.27 ENST00000603713.1
ENST00000603313.1
BNC2
basonuclin 2
chr7_-_100860851 0.26 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr3_-_101039402 0.26 ENST00000193391.7
IMPG2
interphotoreceptor matrix proteoglycan 2
chr1_-_149859466 0.26 ENST00000331128.3
HIST2H2AB
histone cluster 2, H2ab
chr3_-_141747950 0.25 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr11_-_85430356 0.25 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr1_-_169396646 0.25 ENST00000367806.3
CCDC181
coiled-coil domain containing 181
chr3_-_100565249 0.25 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr1_+_199996702 0.25 ENST00000367362.3
NR5A2
nuclear receptor subfamily 5, group A, member 2
chr12_-_16761007 0.25 ENST00000354662.1
ENST00000441439.2
LMO3
LIM domain only 3 (rhombotin-like 2)
chr7_+_114055052 0.24 ENST00000462331.1
ENST00000408937.3
ENST00000403559.4
ENST00000350908.4
ENST00000393498.2
ENST00000393495.3
ENST00000378237.3
ENST00000393489.3
FOXP2
forkhead box P2
chr4_-_119759795 0.24 ENST00000419654.2
SEC24D
SEC24 family member D
chr6_+_39760129 0.24 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr11_-_26593649 0.24 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr1_-_1709845 0.24 ENST00000341426.5
ENST00000344463.4
NADK
NAD kinase
chr12_-_32908809 0.23 ENST00000324868.8
YARS2
tyrosyl-tRNA synthetase 2, mitochondrial
chr1_+_62439037 0.23 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr1_-_212965104 0.23 ENST00000422588.2
ENST00000366975.6
ENST00000366977.3
ENST00000366976.1
NSL1
NSL1, MIS12 kinetochore complex component
chr7_-_14028488 0.22 ENST00000405358.4
ETV1
ets variant 1
chr8_-_42358742 0.22 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_-_53171128 0.22 ENST00000332411.2
KRT76
keratin 76
chr4_-_140544386 0.22 ENST00000561977.1
RP11-308D13.3
RP11-308D13.3
chr13_+_102104952 0.22 ENST00000376180.3
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr4_-_103749179 0.22 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chrX_-_106243451 0.21 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr21_+_30672433 0.21 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chrX_-_19817869 0.21 ENST00000379698.4
SH3KBP1
SH3-domain kinase binding protein 1
chr15_+_41913690 0.21 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr3_+_69985792 0.21 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr14_+_72052983 0.20 ENST00000358550.2
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr18_+_55888767 0.20 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr1_+_107683436 0.20 ENST00000370068.1
NTNG1
netrin G1
chr4_+_95916947 0.20 ENST00000506363.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr3_+_115342349 0.20 ENST00000393780.3
GAP43
growth associated protein 43
chr1_+_1846519 0.20 ENST00000378604.3
CALML6
calmodulin-like 6
chr1_+_36621529 0.19 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr12_-_16762971 0.19 ENST00000540590.1
LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_+_131062367 0.19 ENST00000601297.1
AL359091.2
CDNA: FLJ21673 fis, clone COL09042; HCG2036511; Uncharacterized protein
chr7_+_100860949 0.19 ENST00000305105.2
ZNHIT1
zinc finger, HIT-type containing 1
chr8_+_9953061 0.19 ENST00000522907.1
ENST00000528246.1
MSRA
methionine sulfoxide reductase A
chr13_+_78315528 0.18 ENST00000496045.1
SLAIN1
SLAIN motif family, member 1
chrX_-_13835147 0.18 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr12_-_21928515 0.18 ENST00000537950.1
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chrX_-_46187069 0.18 ENST00000446884.1
RP1-30G7.2
RP1-30G7.2
chr12_-_6233828 0.18 ENST00000572068.1
ENST00000261405.5
VWF
von Willebrand factor
chr2_-_99871570 0.18 ENST00000333017.2
ENST00000409679.1
ENST00000423306.1
LYG2
lysozyme G-like 2
chr5_-_54988559 0.18 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr19_-_12889226 0.18 ENST00000589400.1
ENST00000590839.1
ENST00000592079.1
HOOK2
hook microtubule-tethering protein 2
chr4_+_144354644 0.17 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr8_+_32579341 0.17 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr14_-_95236551 0.17 ENST00000238558.3
GSC
goosecoid homeobox
chr15_+_28624878 0.17 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr1_+_160370344 0.17 ENST00000368061.2
VANGL2
VANGL planar cell polarity protein 2
chr1_-_201140673 0.17 ENST00000367333.2
TMEM9
transmembrane protein 9
chr5_-_140998616 0.17 ENST00000389054.3
ENST00000398562.2
ENST00000389057.5
ENST00000398566.3
ENST00000398557.4
ENST00000253811.6
DIAPH1
diaphanous-related formin 1
chr18_+_32173276 0.17 ENST00000591816.1
ENST00000588125.1
ENST00000598334.1
ENST00000588684.1
ENST00000554864.3
ENST00000399121.5
ENST00000595022.1
ENST00000269190.7
ENST00000399097.3
DTNA
dystrobrevin, alpha
chr3_-_38071122 0.17 ENST00000334661.4
PLCD1
phospholipase C, delta 1
chr21_+_29911640 0.17 ENST00000412526.1
ENST00000455939.1
LINC00161
long intergenic non-protein coding RNA 161
chr14_-_78083112 0.16 ENST00000216484.2
SPTLC2
serine palmitoyltransferase, long chain base subunit 2
chr13_+_102104980 0.16 ENST00000545560.2
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr6_-_25042231 0.16 ENST00000510784.2
FAM65B
family with sequence similarity 65, member B
chr13_-_99667960 0.16 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr17_-_9929581 0.16 ENST00000437099.2
ENST00000396115.2
GAS7
growth arrest-specific 7
chr7_-_81399438 0.16 ENST00000222390.5
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr20_-_50419055 0.16 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr15_+_48498480 0.16 ENST00000380993.3
ENST00000396577.3
SLC12A1
solute carrier family 12 (sodium/potassium/chloride transporter), member 1
chr5_-_96478466 0.16 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr18_+_59000815 0.16 ENST00000262717.4
CDH20
cadherin 20, type 2
chr1_-_232651312 0.16 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chrX_-_18690210 0.15 ENST00000379984.3
RS1
retinoschisin 1
chr2_-_145188137 0.15 ENST00000440875.1
ZEB2
zinc finger E-box binding homeobox 2
chr15_-_55563072 0.15 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A
RAB27A, member RAS oncogene family
chr20_-_49307897 0.15 ENST00000535356.1
FAM65C
family with sequence similarity 65, member C
chr5_-_36301984 0.14 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr14_+_74034310 0.14 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr4_-_69111401 0.14 ENST00000332644.5
TMPRSS11B
transmembrane protease, serine 11B
chr7_+_6655225 0.14 ENST00000457543.3
ZNF853
zinc finger protein 853
chr6_+_13272904 0.14 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr15_+_43985725 0.13 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr21_+_17443434 0.13 ENST00000400178.2
LINC00478
long intergenic non-protein coding RNA 478
chr1_+_45241109 0.13 ENST00000396651.3
RPS8
ribosomal protein S8
chr12_+_15699286 0.13 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO
protein tyrosine phosphatase, receptor type, O
chr15_-_65407524 0.13 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr19_+_36632204 0.13 ENST00000592354.1
CAPNS1
calpain, small subunit 1
chr15_+_80351977 0.13 ENST00000559157.1
ENST00000561012.1
ENST00000564367.1
ENST00000558494.1
ZFAND6
zinc finger, AN1-type domain 6
chr20_+_62795827 0.12 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr6_+_150920999 0.12 ENST00000367328.1
ENST00000367326.1
PLEKHG1
pleckstrin homology domain containing, family G (with RhoGef domain) member 1
chr10_-_21435488 0.12 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113
chromosome 10 open reading frame 113
chr14_-_69261310 0.12 ENST00000336440.3
ZFP36L1
ZFP36 ring finger protein-like 1
chr14_+_39944025 0.12 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
RP11-111A21.1
chr7_-_73038867 0.12 ENST00000313375.3
ENST00000354613.1
ENST00000395189.1
ENST00000453275.1
MLXIPL
MLX interacting protein-like
chr2_-_50574856 0.12 ENST00000342183.5
NRXN1
neurexin 1
chr11_+_125034586 0.12 ENST00000298282.9
PKNOX2
PBX/knotted 1 homeobox 2
chr8_-_7243080 0.12 ENST00000400156.4
ZNF705G
zinc finger protein 705G
chr7_-_73038822 0.12 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLXIPL
MLX interacting protein-like
chrX_+_7137475 0.12 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr1_-_68698222 0.12 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr9_-_28670283 0.12 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr12_-_50643664 0.11 ENST00000550592.1
LIMA1
LIM domain and actin binding 1
chr18_-_53019208 0.11 ENST00000562607.1
TCF4
transcription factor 4
chr8_-_37457350 0.11 ENST00000519691.1
RP11-150O12.3
RP11-150O12.3
chr14_-_47351391 0.11 ENST00000399222.3
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr1_-_10532531 0.11 ENST00000377036.2
ENST00000377038.3
DFFA
DNA fragmentation factor, 45kDa, alpha polypeptide
chr3_-_112127981 0.11 ENST00000486726.2
RP11-231E6.1
RP11-231E6.1
chr16_-_85617170 0.11 ENST00000602862.1
RP11-118F19.1
RP11-118F19.1
chr10_+_114710425 0.11 ENST00000352065.5
ENST00000369395.1
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr4_-_103749205 0.11 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr10_+_119302508 0.11 ENST00000442245.4
EMX2
empty spiracles homeobox 2
chr3_-_98235962 0.11 ENST00000513873.1
CLDND1
claudin domain containing 1
chr2_+_196313239 0.10 ENST00000413290.1
AC064834.1
AC064834.1
chr12_+_56325812 0.10 ENST00000394147.1
ENST00000551156.1
ENST00000553783.1
ENST00000557080.1
ENST00000432422.3
ENST00000556001.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr20_-_31124186 0.10 ENST00000375678.3
C20orf112
chromosome 20 open reading frame 112
chr8_+_22844995 0.10 ENST00000524077.1
RHOBTB2
Rho-related BTB domain containing 2
chr1_-_2458026 0.10 ENST00000435556.3
ENST00000378466.3
PANK4
pantothenate kinase 4
chr9_+_125132803 0.10 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

Network of associatons between targets according to the STRING database.

First level regulatory network of PDX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 0.7 GO:0019082 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.2 1.3 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.2 1.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 0.7 GO:0001757 somite specification(GO:0001757)
0.2 0.6 GO:0048631 negative regulation of skeletal muscle cell proliferation(GO:0014859) regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.4 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.4 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.4 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.6 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.1 0.9 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.5 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0051795 catagen(GO:0042637) regulation of catagen(GO:0051794) positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.1 0.9 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.1 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.7 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.3 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.1 0.3 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.1 0.2 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.5 GO:0097324 melanocyte migration(GO:0097324) positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.1 0.2 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.6 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.5 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.0 0.4 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 1.3 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.4 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.7 GO:0007625 grooming behavior(GO:0007625)
0.0 0.1 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.3 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.7 GO:0072662 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 0.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0016198 axon choice point recognition(GO:0016198)
0.0 1.1 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.0 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1904721 negative regulation of mRNA cleavage(GO:0031438) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.0 GO:0061349 chemoattraction of serotonergic neuron axon(GO:0036517) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) chemoattraction of axon(GO:0061642) negative regulation of cell proliferation in midbrain(GO:1904934) planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation(GO:1904955)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.0 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.7 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.7 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.7 GO:0032982 myosin filament(GO:0032982)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.3 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.2 1.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.7 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.9 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.3 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.1 0.2 GO:0008511 sodium:potassium:chloride symporter activity(GO:0008511)
0.0 0.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.6 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0015254 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.1 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.0 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.5 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.0 GO:1902379 receptor tyrosine kinase-like orphan receptor binding(GO:0005115) chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.7 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.3 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins