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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PAX6

Z-value: 1.27

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Transcription factors associated with PAX6

Gene Symbol Gene ID Gene Info
PAX6
ENSG00000007372.16 paired box 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX6hg19_v2_chr11_-_31839488_318395150.919.4e-02Click!

Activity profile of PAX6 motif

Sorted Z-values of PAX6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_121476959 1.75 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr1_+_79115503 1.58 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
IFI44
interferon-induced protein 44
chr12_+_113354341 1.53 ENST00000553152.1
OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_+_91092241 1.44 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr12_-_10007448 0.89 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr12_-_78934441 0.87 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
RP11-171L9.1
chr19_-_36019123 0.61 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr1_+_223354486 0.59 ENST00000446145.1
RP11-239E10.3
RP11-239E10.3
chr8_-_19614810 0.57 ENST00000524213.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr20_+_48807351 0.55 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr3_+_108015382 0.53 ENST00000463019.3
ENST00000491820.1
ENST00000467562.1
ENST00000482430.1
ENST00000462629.1
HHLA2
HERV-H LTR-associating 2
chr22_-_30968813 0.52 ENST00000443111.2
ENST00000443136.1
ENST00000426220.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chrX_-_124097620 0.49 ENST00000371130.3
ENST00000422452.2
TENM1
teneurin transmembrane protein 1
chr19_-_37701386 0.46 ENST00000527838.1
ENST00000591492.1
ENST00000532828.2
ZNF585B
zinc finger protein 585B
chr22_-_30968839 0.45 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr18_-_21242774 0.45 ENST00000322980.9
ANKRD29
ankyrin repeat domain 29
chr4_-_129491686 0.44 ENST00000514265.1
RP11-184M15.1
RP11-184M15.1
chr2_-_86116020 0.44 ENST00000525834.2
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr16_+_77233294 0.43 ENST00000378644.4
SYCE1L
synaptonemal complex central element protein 1-like
chr12_+_113416340 0.42 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr18_+_61445205 0.41 ENST00000431370.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chrX_+_10126488 0.41 ENST00000380829.1
ENST00000421085.2
ENST00000454850.1
CLCN4
chloride channel, voltage-sensitive 4
chr19_+_35939154 0.41 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr12_+_10460417 0.40 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
KLRD1
killer cell lectin-like receptor subfamily D, member 1
chr12_-_3982511 0.40 ENST00000427057.2
ENST00000228820.4
PARP11
poly (ADP-ribose) polymerase family, member 11
chr5_+_67485704 0.40 ENST00000520762.1
RP11-404L6.2
Uncharacterized protein
chr18_-_21242833 0.39 ENST00000586087.1
ENST00000592179.1
ANKRD29
ankyrin repeat domain 29
chr21_+_39628655 0.39 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr4_+_130017268 0.37 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
C4orf33
chromosome 4 open reading frame 33
chr14_-_36645674 0.37 ENST00000556013.2
PTCSC3
papillary thyroid carcinoma susceptibility candidate 3 (non-protein coding)
chr9_-_140142222 0.35 ENST00000344774.4
ENST00000388932.2
FAM166A
family with sequence similarity 166, member A
chr4_+_129349188 0.34 ENST00000511497.1
RP11-420A23.1
RP11-420A23.1
chr20_+_32250079 0.34 ENST00000375222.3
C20orf144
chromosome 20 open reading frame 144
chr1_+_207818460 0.34 ENST00000508064.2
CR1L
complement component (3b/4b) receptor 1-like
chr4_+_123747979 0.32 ENST00000608478.1
FGF2
fibroblast growth factor 2 (basic)
chr4_+_70916119 0.32 ENST00000246896.3
ENST00000511674.1
HTN1
histatin 1
chr4_+_70894130 0.31 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr1_-_110933663 0.30 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr1_-_2126192 0.30 ENST00000378546.4
C1orf86
chromosome 1 open reading frame 86
chr8_-_18711866 0.30 ENST00000519851.1
PSD3
pleckstrin and Sec7 domain containing 3
chr22_+_39745930 0.30 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
SYNGR1
synaptogyrin 1
chr9_+_127023704 0.30 ENST00000373596.1
ENST00000425237.1
NEK6
NIMA-related kinase 6
chr12_+_83080724 0.29 ENST00000548305.1
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr12_+_93115281 0.29 ENST00000549856.1
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr3_+_140981456 0.29 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr12_-_3982548 0.28 ENST00000397096.2
ENST00000447133.3
ENST00000450737.2
PARP11
poly (ADP-ribose) polymerase family, member 11
chr11_+_74811578 0.28 ENST00000531713.1
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr3_-_119182506 0.27 ENST00000468676.1
TMEM39A
transmembrane protein 39A
chrX_-_80457385 0.27 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5
high mobility group nucleosome binding domain 5
chr9_-_16870704 0.27 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr22_-_36220420 0.26 ENST00000473487.2
RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_-_110933611 0.26 ENST00000472422.2
ENST00000437429.2
SLC16A4
solute carrier family 16, member 4
chrX_+_106449862 0.26 ENST00000372453.3
ENST00000535523.1
PIH1D3
PIH1 domain containing 3
chr3_-_171489085 0.26 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr1_-_232598163 0.26 ENST00000308942.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr19_-_10047219 0.26 ENST00000264833.4
OLFM2
olfactomedin 2
chr2_+_149402989 0.26 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr3_+_171561127 0.26 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr6_+_42896865 0.25 ENST00000372836.4
ENST00000394142.3
CNPY3
canopy FGF signaling regulator 3
chr13_+_53602894 0.25 ENST00000219022.2
OLFM4
olfactomedin 4
chr5_-_159766528 0.25 ENST00000505287.2
CCNJL
cyclin J-like
chr12_-_122884553 0.25 ENST00000535290.1
CLIP1
CAP-GLY domain containing linker protein 1
chr12_-_69080590 0.25 ENST00000433116.2
ENST00000500695.2
RP11-637A17.2
RP11-637A17.2
chr7_-_91808845 0.25 ENST00000343318.5
LRRD1
leucine-rich repeats and death domain containing 1
chr18_+_61445007 0.25 ENST00000447428.1
ENST00000546027.1
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr12_+_78224667 0.25 ENST00000549464.1
NAV3
neuron navigator 3
chr2_-_158182322 0.25 ENST00000420719.2
ENST00000409216.1
ERMN
ermin, ERM-like protein
chr6_-_26033796 0.24 ENST00000259791.2
HIST1H2AB
histone cluster 1, H2ab
chr2_-_158182105 0.24 ENST00000409925.1
ERMN
ermin, ERM-like protein
chr4_-_10686475 0.24 ENST00000226951.6
CLNK
cytokine-dependent hematopoietic cell linker
chr12_-_85306594 0.23 ENST00000266682.5
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr1_+_244227632 0.23 ENST00000598000.1
AL590483.1
Uncharacterized protein; cDNA FLJ42623 fis, clone BRACE3015894
chr3_-_124839648 0.23 ENST00000430155.2
SLC12A8
solute carrier family 12, member 8
chr4_-_174320687 0.23 ENST00000296506.3
SCRG1
stimulator of chondrogenesis 1
chr17_+_36283971 0.23 ENST00000327454.6
ENST00000378174.5
TBC1D3F
TBC1 domain family, member 3F
chr6_-_30684898 0.22 ENST00000422266.1
ENST00000416571.1
MDC1
mediator of DNA-damage checkpoint 1
chr17_+_25958174 0.22 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
LGALS9
lectin, galactoside-binding, soluble, 9
chr2_+_114195268 0.22 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
CBWD2
COBW domain containing 2
chr7_+_76109827 0.22 ENST00000446820.2
DTX2
deltex homolog 2 (Drosophila)
chr22_-_30642728 0.22 ENST00000403987.3
LIF
leukemia inhibitory factor
chr12_-_70093162 0.22 ENST00000551160.1
BEST3
bestrophin 3
chr14_+_57671888 0.21 ENST00000391612.1
AL391152.1
AL391152.1
chr3_+_151531810 0.21 ENST00000232892.7
AADAC
arylacetamide deacetylase
chr5_+_96212185 0.21 ENST00000379904.4
ERAP2
endoplasmic reticulum aminopeptidase 2
chr2_-_86116093 0.20 ENST00000377332.3
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_+_180897269 0.20 ENST00000367587.1
KIAA1614
KIAA1614
chr2_-_153573965 0.20 ENST00000448428.1
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr2_+_179184955 0.19 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr3_+_15045419 0.19 ENST00000406272.2
NR2C2
nuclear receptor subfamily 2, group C, member 2
chr18_+_61420169 0.19 ENST00000425392.1
ENST00000336429.2
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr15_+_51973708 0.19 ENST00000558709.1
SCG3
secretogranin III
chr6_+_170151708 0.19 ENST00000592367.1
ENST00000590711.1
ENST00000366772.2
ENST00000592745.1
ENST00000392095.4
ENST00000366773.3
ENST00000586341.1
ENST00000418781.3
ENST00000588437.1
ERMARD
ER membrane-associated RNA degradation
chr6_+_26156551 0.18 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chrX_-_53461305 0.17 ENST00000168216.6
HSD17B10
hydroxysteroid (17-beta) dehydrogenase 10
chr3_-_111852061 0.17 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr2_+_196522032 0.17 ENST00000418005.1
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr12_+_56915713 0.17 ENST00000262031.5
ENST00000552247.2
RBMS2
RNA binding motif, single stranded interacting protein 2
chr7_-_43909090 0.17 ENST00000317534.5
MRPS24
mitochondrial ribosomal protein S24
chr8_+_102064237 0.17 ENST00000514926.1
RP11-302J23.1
RP11-302J23.1
chr3_-_87842631 0.16 ENST00000462792.1
RP11-451B8.1
RP11-451B8.1
chr8_-_19615382 0.16 ENST00000544602.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr17_+_16945820 0.16 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr11_-_3078838 0.16 ENST00000397111.5
CARS
cysteinyl-tRNA synthetase
chr2_+_228189867 0.16 ENST00000423098.1
ENST00000304593.9
MFF
mitochondrial fission factor
chr8_-_62602327 0.16 ENST00000445642.3
ENST00000517847.2
ENST00000389204.4
ENST00000517661.1
ENST00000517903.1
ENST00000522603.1
ENST00000522349.1
ENST00000522835.1
ENST00000541428.1
ENST00000518306.1
ASPH
aspartate beta-hydroxylase
chr17_-_73389737 0.16 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr3_+_151531859 0.16 ENST00000488869.1
AADAC
arylacetamide deacetylase
chrX_-_138914394 0.16 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATP11C
ATPase, class VI, type 11C
chr7_-_150754935 0.16 ENST00000297518.4
CDK5
cyclin-dependent kinase 5
chr16_+_72088376 0.16 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
HP
HPR
haptoglobin
haptoglobin-related protein
chr8_-_19615538 0.15 ENST00000517494.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_-_162931052 0.15 ENST00000360534.3
DPP4
dipeptidyl-peptidase 4
chr12_-_70093235 0.15 ENST00000266661.4
BEST3
bestrophin 3
chr1_-_87379785 0.15 ENST00000401030.3
ENST00000370554.1
SEP15
Homo sapiens 15 kDa selenoprotein (SEP15), transcript variant 2, mRNA.
chr2_+_119699864 0.15 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr1_-_2126174 0.15 ENST00000400919.3
ENST00000420515.1
ENST00000378543.2
ENST00000400918.3
C1orf86
chromosome 1 open reading frame 86
chr11_+_14926543 0.15 ENST00000523376.1
CALCB
calcitonin-related polypeptide beta
chr3_-_111852128 0.14 ENST00000308910.4
GCSAM
germinal center-associated, signaling and motility
chr5_+_53686658 0.14 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr6_-_134373732 0.14 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr1_-_85725316 0.14 ENST00000344356.5
ENST00000471115.1
C1orf52
chromosome 1 open reading frame 52
chr12_-_15103621 0.14 ENST00000536592.1
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr2_+_168675182 0.14 ENST00000305861.1
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr17_-_77023683 0.14 ENST00000581579.1
C1QTNF1-AS1
C1QTNF1 antisense RNA 1
chr17_-_73266616 0.14 ENST00000579194.1
ENST00000581777.1
MIF4GD
MIF4G domain containing
chr20_+_9966728 0.14 ENST00000449270.1
RP5-839B4.8
RP5-839B4.8
chr5_-_114938090 0.13 ENST00000427199.2
TICAM2
toll-like receptor adaptor molecule 2
chr15_+_68924327 0.13 ENST00000543950.1
CORO2B
coronin, actin binding protein, 2B
chr12_+_47473369 0.13 ENST00000546455.1
PCED1B
PC-esterase domain containing 1B
chr11_-_102401469 0.13 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr9_+_131549483 0.12 ENST00000372648.5
ENST00000539497.1
TBC1D13
TBC1 domain family, member 13
chr17_-_58096336 0.12 ENST00000587125.1
ENST00000407042.3
TBC1D3P1-DHX40P1
TBC1D3P1-DHX40P1 readthrough transcribed pseudogene
chr12_+_83080659 0.12 ENST00000321196.3
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr4_-_88141615 0.12 ENST00000545252.1
ENST00000425278.2
ENST00000498875.2
KLHL8
kelch-like family member 8
chr2_+_238877424 0.12 ENST00000434655.1
UBE2F
ubiquitin-conjugating enzyme E2F (putative)
chr6_-_43027105 0.12 ENST00000230413.5
ENST00000487429.1
ENST00000489623.1
ENST00000468957.1
MRPL2
mitochondrial ribosomal protein L2
chr1_+_39491984 0.12 ENST00000372969.3
ENST00000372967.3
NDUFS5
NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase)
chr5_-_58882219 0.12 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr19_+_50936142 0.12 ENST00000357701.5
MYBPC2
myosin binding protein C, fast type
chr14_+_29241910 0.12 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr1_-_23504176 0.12 ENST00000302291.4
LUZP1
leucine zipper protein 1
chr15_-_78358465 0.12 ENST00000435468.1
TBC1D2B
TBC1 domain family, member 2B
chr22_-_37571089 0.11 ENST00000453962.1
ENST00000429622.1
ENST00000445595.1
IL2RB
interleukin 2 receptor, beta
chr7_-_150864635 0.11 ENST00000297537.4
GBX1
gastrulation brain homeobox 1
chr8_+_41347915 0.11 ENST00000518270.1
ENST00000520817.1
GOLGA7
golgin A7
chr1_+_218683438 0.11 ENST00000443836.1
C1orf143
chromosome 1 open reading frame 143
chr6_+_143447322 0.11 ENST00000458219.1
AIG1
androgen-induced 1
chr2_-_677369 0.11 ENST00000281017.3
TMEM18
transmembrane protein 18
chr11_+_33563618 0.11 ENST00000526400.1
KIAA1549L
KIAA1549-like
chr2_-_158182410 0.11 ENST00000419116.2
ENST00000410096.1
ERMN
ermin, ERM-like protein
chr16_+_77822427 0.11 ENST00000302536.2
VAT1L
vesicle amine transport 1-like
chr8_-_59412717 0.11 ENST00000301645.3
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr2_-_154335300 0.11 ENST00000325926.3
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr10_-_104597286 0.11 ENST00000369887.3
CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr1_+_15668240 0.11 ENST00000444385.1
FHAD1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr6_-_88299678 0.11 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr12_+_56915776 0.10 ENST00000550726.1
ENST00000542360.1
RBMS2
RNA binding motif, single stranded interacting protein 2
chr7_-_138348969 0.10 ENST00000436657.1
SVOPL
SVOP-like
chr4_+_123747834 0.10 ENST00000264498.3
FGF2
fibroblast growth factor 2 (basic)
chr2_+_29320571 0.10 ENST00000401605.1
ENST00000401617.2
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr5_-_55529115 0.10 ENST00000513241.2
ENST00000341048.4
ANKRD55
ankyrin repeat domain 55
chrX_-_92928557 0.10 ENST00000373079.3
ENST00000475430.2
NAP1L3
nucleosome assembly protein 1-like 3
chr6_-_26043885 0.10 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr2_+_202098166 0.10 ENST00000392263.2
ENST00000264274.9
ENST00000392259.2
ENST00000392266.3
ENST00000432109.2
ENST00000264275.5
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr4_+_40751914 0.10 ENST00000381782.2
ENST00000316607.5
NSUN7
NOP2/Sun domain family, member 7
chr16_+_89228757 0.10 ENST00000565008.1
LINC00304
long intergenic non-protein coding RNA 304
chr18_+_13611431 0.10 ENST00000587757.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr9_+_131549610 0.10 ENST00000223865.8
TBC1D13
TBC1 domain family, member 13
chr5_+_322733 0.10 ENST00000515206.1
AHRR
aryl-hydrocarbon receptor repressor
chr15_+_51973680 0.10 ENST00000542355.2
SCG3
secretogranin III
chr12_+_111284764 0.10 ENST00000545036.1
ENST00000308208.5
CCDC63
coiled-coil domain containing 63
chr4_+_40194609 0.10 ENST00000508513.1
RHOH
ras homolog family member H
chr12_-_106697974 0.10 ENST00000553039.1
CKAP4
cytoskeleton-associated protein 4
chr7_+_90338712 0.09 ENST00000265741.3
ENST00000406263.1
CDK14
cyclin-dependent kinase 14
chr19_-_50370509 0.09 ENST00000596014.1
PNKP
polynucleotide kinase 3'-phosphatase
chr18_+_18822185 0.09 ENST00000424526.1
ENST00000400483.4
ENST00000431264.1
GREB1L
growth regulation by estrogen in breast cancer-like
chr15_+_42565393 0.09 ENST00000561871.1
GANC
glucosidase, alpha; neutral C
chr7_-_76255444 0.09 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr21_+_39628780 0.09 ENST00000417042.1
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_85306562 0.09 ENST00000551612.1
ENST00000450363.3
ENST00000552192.1
SLC6A15
solute carrier family 6 (neutral amino acid transporter), member 15
chr15_-_23034322 0.09 ENST00000539711.2
ENST00000560039.1
ENST00000398013.3
ENST00000337451.3
ENST00000359727.4
ENST00000398014.2
NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr11_+_65554493 0.09 ENST00000335987.3
OVOL1
ovo-like zinc finger 1
chr4_+_115519577 0.09 ENST00000310836.6
UGT8
UDP glycosyltransferase 8
chr1_+_203651937 0.09 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr5_-_98262240 0.09 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr9_+_87283430 0.09 ENST00000376214.1
ENST00000376213.1
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr3_-_157251383 0.09 ENST00000487753.1
ENST00000489602.1
ENST00000461299.1
ENST00000479987.1
VEPH1
ventricular zone expressed PH domain-containing 1
chr19_+_51628165 0.08 ENST00000250360.3
ENST00000440804.3
SIGLEC9
sialic acid binding Ig-like lectin 9
chr13_-_24007815 0.08 ENST00000382298.3
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr17_+_72270429 0.08 ENST00000311014.6
DNAI2
dynein, axonemal, intermediate chain 2
chr15_-_65282274 0.08 ENST00000204566.2
SPG21
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
chr2_+_202098203 0.08 ENST00000450491.1
ENST00000440732.1
ENST00000392258.3
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr2_-_74776586 0.08 ENST00000420535.1
LOXL3
lysyl oxidase-like 3
chr11_+_128563652 0.08 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr18_+_13611763 0.08 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr19_-_41903161 0.08 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
EXOSC5
exosome component 5
chrX_-_15332665 0.08 ENST00000537676.1
ENST00000344384.4
ASB11
ankyrin repeat and SOCS box containing 11
chr12_+_59194154 0.08 ENST00000548969.1
RP11-362K2.2
Protein LOC100506869
chr6_-_131291572 0.08 ENST00000529208.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr4_+_113970772 0.07 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2
ankyrin 2, neuronal

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.4 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.1 0.4 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 0.9 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 1.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 1.4 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.2 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.2 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.1 0.2 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0021503 neural fold bending(GO:0021503)
0.0 0.4 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.2 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.2 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 0.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.6 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.0 0.3 GO:0015820 leucine transport(GO:0015820) proline transmembrane transport(GO:0035524)
0.0 3.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.3 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.1 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:2000389 regulation of neutrophil extravasation(GO:2000389)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0019230 proprioception(GO:0019230)
0.0 0.1 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.6 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.5 GO:0042104 positive regulation of activated T cell proliferation(GO:0042104)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.5 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:0019075 virus maturation(GO:0019075)
0.0 0.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.2 GO:0045199 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0000023 maltose metabolic process(GO:0000023)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.6 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.7 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 0.6 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.1 0.9 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.1 1.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.1 0.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.2 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.1 0.2 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.3 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.2 GO:0030548 ErbB-2 class receptor binding(GO:0005176) acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.1 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.3 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits