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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for PAX1_PAX9

Z-value: 0.15

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Transcription factors associated with PAX1_PAX9

Gene Symbol Gene ID Gene Info
ENSG00000125813.9 paired box 1
ENSG00000198807.8 paired box 9

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PAX9hg19_v2_chr14_+_37131058_37131139-0.831.7e-01Click!
PAX1hg19_v2_chr20_+_21686290_21686311-0.178.3e-01Click!

Activity profile of PAX1_PAX9 motif

Sorted Z-values of PAX1_PAX9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_23261589 0.32 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
lysyl oxidase-like 2
chr8_-_23282797 0.25 ENST00000524144.1
lysyl oxidase-like 2
chr8_-_23282820 0.23 ENST00000520871.1
lysyl oxidase-like 2
chr4_+_75230853 0.17 ENST00000244869.2
epiregulin
chr18_-_47813940 0.16 ENST00000586837.1
ENST00000412036.2
ENST00000589940.1
CXXC finger protein 1
chr18_-_47814032 0.15 ENST00000589548.1
ENST00000591474.1
CXXC finger protein 1
chrX_-_153707545 0.11 ENST00000357360.4
L antigen family, member 3
chr2_+_119699864 0.10 ENST00000541757.1
ENST00000412481.1
macrophage receptor with collagenous structure
chrX_-_153707246 0.08 ENST00000407062.1
L antigen family, member 3
chr20_-_17641097 0.07 ENST00000246043.4
ribosome binding protein 1
chr11_-_67397371 0.06 ENST00000376693.2
ENST00000301490.4
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr21_-_33104367 0.05 ENST00000286835.7
ENST00000399804.1
SR-related CTD-associated factor 4
chr4_+_123747979 0.05 ENST00000608478.1
fibroblast growth factor 2 (basic)
chr19_-_39104556 0.04 ENST00000423454.2
mitogen-activated protein kinase kinase kinase kinase 1
chr7_-_2349579 0.04 ENST00000435060.1
sorting nexin 8
chr7_-_19157248 0.04 ENST00000242261.5
twist family bHLH transcription factor 1
chr19_-_40791211 0.04 ENST00000579047.1
v-akt murine thymoma viral oncogene homolog 2
chr19_-_409134 0.04 ENST00000332235.6
C2 calcium-dependent domain containing 4C
chr5_-_133747551 0.04 ENST00000395009.3
CDKN2A interacting protein N-terminal like
chr18_-_33077556 0.03 ENST00000589273.1
ENST00000586489.1
INO80 complex subunit C
chr16_+_67197288 0.03 ENST00000264009.8
ENST00000421453.1
heat shock transcription factor 4
chr6_-_137366163 0.03 ENST00000367748.1
interleukin 20 receptor, alpha
chr2_+_234160217 0.03 ENST00000392017.4
ENST00000347464.5
ENST00000444735.1
ENST00000373525.5
ENST00000419681.1
autophagy related 16-like 1 (S. cerevisiae)
chr7_-_22234381 0.03 ENST00000458533.1
Rap guanine nucleotide exchange factor (GEF) 5
chr2_+_234160340 0.02 ENST00000417017.1
ENST00000392020.4
ENST00000392018.1
autophagy related 16-like 1 (S. cerevisiae)
chr17_-_7137582 0.02 ENST00000575756.1
ENST00000575458.1
dishevelled segment polarity protein 2
chr7_-_144533074 0.02 ENST00000360057.3
ENST00000378099.3
thiamin pyrophosphokinase 1
chr19_-_5838768 0.02 ENST00000527106.1
ENST00000531199.1
ENST00000529165.1
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr17_+_37356528 0.02 ENST00000225430.4
ribosomal protein L19
chr11_-_126138808 0.02 ENST00000332118.6
ENST00000532259.1
signal recognition particle receptor (docking protein)
chr8_+_102064237 0.02 ENST00000514926.1
RP11-302J23.1
chr11_+_12308447 0.02 ENST00000256186.2
MICAL C-terminal like
chr14_-_69261310 0.02 ENST00000336440.3
ZFP36 ring finger protein-like 1
chr18_-_47018769 0.02 ENST00000583637.1
ENST00000578528.1
ENST00000578532.1
ENST00000580387.1
ENST00000579248.1
ENST00000581373.1
ribosomal protein L17
chr11_+_6947720 0.02 ENST00000414517.2
zinc finger protein 215
chr17_+_76374714 0.02 ENST00000262764.6
ENST00000589689.1
ENST00000329897.7
ENST00000592043.1
ENST00000587356.1
phosphatidylglycerophosphate synthase 1
chr10_-_99393242 0.02 ENST00000370635.3
ENST00000478953.1
ENST00000335628.3
MORN repeat containing 4
chr6_+_159291090 0.02 ENST00000367073.4
ENST00000608817.1
chromosome 6 open reading frame 99
chr17_+_37356586 0.02 ENST00000579260.1
ENST00000582193.1
ribosomal protein L19
chr17_+_37356555 0.02 ENST00000579374.1
ribosomal protein L19
chr17_-_39968406 0.01 ENST00000393928.1
leprecan-like 4
chr18_-_47017956 0.01 ENST00000584895.1
ENST00000332968.6
ENST00000580210.1
ENST00000579408.1
RPL17-C18orf32 readthrough
ribosomal protein L17
chr2_-_175711978 0.01 ENST00000409089.2
chimerin 1
chr3_+_127771212 0.01 ENST00000243253.3
ENST00000481210.1
Sec61 alpha 1 subunit (S. cerevisiae)
chrX_+_148622513 0.01 ENST00000393985.3
ENST00000423421.1
ENST00000423540.2
ENST00000434353.2
ENST00000514208.1
chromosome X open reading frame 40A
chr1_+_45140360 0.01 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
chromosome 1 open reading frame 228
chr6_-_137494775 0.01 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
interleukin 22 receptor, alpha 2
chr10_+_82297658 0.01 ENST00000339284.2
SH2 domain containing 4B
chr6_+_74104471 0.01 ENST00000370336.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr1_-_204165610 0.01 ENST00000367194.4
KiSS-1 metastasis-suppressor
chr8_+_39792474 0.01 ENST00000502986.2
indoleamine 2,3-dioxygenase 2
chr10_-_99393208 0.01 ENST00000307450.6
MORN repeat containing 4
chr17_-_39968855 0.01 ENST00000355468.3
ENST00000590496.1
leprecan-like 4
chr22_+_39745930 0.01 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
synaptogyrin 1
chr12_-_101801505 0.01 ENST00000539055.1
ENST00000551688.1
ENST00000551671.1
ENST00000261636.8
ADP-ribosylation factor-like 1
chrX_-_132091284 0.01 ENST00000370833.2
heparan sulfate 6-O-sulfotransferase 2
chr2_-_39414848 0.01 ENST00000451199.1
cyclin-dependent kinase-like 4
chr3_-_57113281 0.01 ENST00000468466.1
Rho guanine nucleotide exchange factor (GEF) 3
chr15_+_63569731 0.01 ENST00000261879.5
APH1B gamma secretase subunit
chr11_+_6947647 0.01 ENST00000278319.5
zinc finger protein 215
chr1_+_26758849 0.00 ENST00000533087.1
ENST00000531312.1
ENST00000525165.1
ENST00000525326.1
ENST00000525546.1
ENST00000436153.2
ENST00000530781.1
dehydrodolichyl diphosphate synthase
chr15_+_63569785 0.00 ENST00000380343.4
ENST00000560353.1
APH1B gamma secretase subunit
chr1_+_26758790 0.00 ENST00000427245.2
ENST00000525682.2
ENST00000236342.7
ENST00000526219.1
ENST00000374185.3
ENST00000360009.2
dehydrodolichyl diphosphate synthase
chr19_-_40791302 0.00 ENST00000392038.2
ENST00000578123.1
v-akt murine thymoma viral oncogene homolog 2
chr9_+_6716478 0.00 ENST00000452643.1
RP11-390F4.3
chr6_+_3118926 0.00 ENST00000380379.5
biphenyl hydrolase-like (serine hydrolase)
chr2_-_162931052 0.00 ENST00000360534.3
dipeptidyl-peptidase 4
chr14_+_64854958 0.00 ENST00000555709.2
ENST00000554739.1
ENST00000554768.1
ENST00000216605.8
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr16_-_84076241 0.00 ENST00000568178.1
solute carrier family 38, member 8
chr5_-_133747589 0.00 ENST00000458198.2
CDKN2A interacting protein N-terminal like
chr4_+_619347 0.00 ENST00000255622.6
phosphodiesterase 6B, cGMP-specific, rod, beta

Network of associatons between targets according to the STRING database.

First level regulatory network of PAX1_PAX9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0018277 protein deamination(GO:0018277)
0.0 0.2 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.0 GO:2000276 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.0 GO:0042660 positive regulation of cell fate specification(GO:0042660)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)