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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for OTX2_CRX

Z-value: 1.04

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Transcription factors associated with OTX2_CRX

Gene Symbol Gene ID Gene Info
OTX2
ENSG00000165588.12 orthodenticle homeobox 2
CRX
ENSG00000105392.11 cone-rod homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CRXhg19_v2_chr19_+_48325097_483252110.406.0e-01Click!

Activity profile of OTX2_CRX motif

Sorted Z-values of OTX2_CRX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_86999516 0.77 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr17_-_4689649 0.76 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr6_+_130339710 0.70 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr1_+_207277632 0.61 ENST00000421786.1
C4BPA
complement component 4 binding protein, alpha
chr17_+_4643337 0.61 ENST00000592813.1
ZMYND15
zinc finger, MYND-type containing 15
chr14_-_95236551 0.58 ENST00000238558.3
GSC
goosecoid homeobox
chr17_-_4643161 0.53 ENST00000574412.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr14_-_22005062 0.53 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr15_+_44092784 0.51 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr6_+_34433844 0.51 ENST00000244458.2
ENST00000374043.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr7_-_100171270 0.45 ENST00000538735.1
SAP25
Sin3A-associated protein, 25kDa
chr17_-_4689727 0.44 ENST00000328739.5
ENST00000354194.4
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr19_-_55866104 0.44 ENST00000326529.4
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr5_+_63461642 0.43 ENST00000296615.6
ENST00000381081.2
ENST00000389100.4
RNF180
ring finger protein 180
chr16_-_58004992 0.42 ENST00000564448.1
ENST00000251102.8
ENST00000311183.4
CNGB1
cyclic nucleotide gated channel beta 1
chr17_-_4643114 0.41 ENST00000293778.6
CXCL16
chemokine (C-X-C motif) ligand 16
chr19_-_55866061 0.40 ENST00000588572.2
ENST00000593184.1
ENST00000589467.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr7_+_73868220 0.38 ENST00000455841.2
GTF2IRD1
GTF2I repeat domain containing 1
chr3_-_54962100 0.38 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr17_-_48207115 0.36 ENST00000511964.1
SAMD14
sterile alpha motif domain containing 14
chr1_+_180875711 0.36 ENST00000434447.1
RP11-46A10.2
RP11-46A10.2
chr13_-_31191642 0.35 ENST00000405805.1
HMGB1
high mobility group box 1
chr3_+_111393659 0.35 ENST00000477665.1
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr17_+_4643300 0.35 ENST00000433935.1
ZMYND15
zinc finger, MYND-type containing 15
chr5_+_138209688 0.35 ENST00000518381.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chrM_+_8366 0.34 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr16_-_31076332 0.33 ENST00000539836.3
ENST00000535577.1
ENST00000442862.2
ZNF668
zinc finger protein 668
chr12_+_85673868 0.33 ENST00000316824.3
ALX1
ALX homeobox 1
chr17_+_68100989 0.31 ENST00000585558.1
ENST00000392670.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr16_-_31076273 0.31 ENST00000426488.2
ZNF668
zinc finger protein 668
chr3_-_149095652 0.29 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr12_+_78224667 0.27 ENST00000549464.1
NAV3
neuron navigator 3
chr1_+_200863949 0.27 ENST00000413687.2
C1orf106
chromosome 1 open reading frame 106
chr15_+_96869165 0.26 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr19_+_48325097 0.26 ENST00000221996.7
ENST00000539067.1
CRX
cone-rod homeobox
chr5_-_41510656 0.25 ENST00000377801.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chrX_-_21676442 0.25 ENST00000379499.2
KLHL34
kelch-like family member 34
chr8_+_54764346 0.24 ENST00000297313.3
ENST00000344277.6
RGS20
regulator of G-protein signaling 20
chr7_-_17500294 0.22 ENST00000439046.1
AC019117.2
AC019117.2
chr19_-_55865908 0.22 ENST00000590900.1
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr17_-_48207157 0.21 ENST00000330175.4
ENST00000503131.1
SAMD14
sterile alpha motif domain containing 14
chr1_-_150208498 0.20 ENST00000314136.8
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_+_21623392 0.20 ENST00000562961.1
METTL9
methyltransferase like 9
chr1_+_164528616 0.20 ENST00000340699.3
PBX1
pre-B-cell leukemia homeobox 1
chr3_+_129247479 0.19 ENST00000296271.3
RHO
rhodopsin
chr6_-_33297013 0.19 ENST00000453407.1
DAXX
death-domain associated protein
chr3_-_186262166 0.18 ENST00000307944.5
CRYGS
crystallin, gamma S
chr9_+_103204553 0.18 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1
TMEFF1
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr13_+_73632897 0.18 ENST00000377687.4
KLF5
Kruppel-like factor 5 (intestinal)
chr7_-_128415844 0.18 ENST00000249389.2
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr10_-_126716459 0.18 ENST00000309035.6
CTBP2
C-terminal binding protein 2
chr9_-_13279563 0.18 ENST00000541718.1
MPDZ
multiple PDZ domain protein
chrX_+_129473859 0.18 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr4_-_102268708 0.18 ENST00000525819.1
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_-_67981870 0.17 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr13_-_52027134 0.17 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr5_-_41510725 0.16 ENST00000328457.3
PLCXD3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr21_-_34915123 0.16 ENST00000438059.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr8_-_42360015 0.15 ENST00000522707.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr12_-_13248598 0.15 ENST00000337630.6
ENST00000545699.1
GSG1
germ cell associated 1
chr14_-_67981916 0.15 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr15_-_27184664 0.15 ENST00000541819.2
GABRB3
gamma-aminobutyric acid (GABA) A receptor, beta 3
chr4_-_15661474 0.14 ENST00000509314.1
ENST00000503196.1
FBXL5
F-box and leucine-rich repeat protein 5
chr22_-_38480100 0.14 ENST00000427592.1
SLC16A8
solute carrier family 16 (monocarboxylate transporter), member 8
chr9_-_131486367 0.14 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12
zinc finger, DHHC-type containing 12
chr1_-_150208412 0.14 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr19_-_59066452 0.13 ENST00000312547.2
CHMP2A
charged multivesicular body protein 2A
chr9_-_13279589 0.13 ENST00000319217.7
MPDZ
multiple PDZ domain protein
chr7_-_83824449 0.13 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_-_170599561 0.13 ENST00000366756.3
DLL1
delta-like 1 (Drosophila)
chr19_-_44123734 0.13 ENST00000598676.1
ZNF428
zinc finger protein 428
chr11_-_111794446 0.13 ENST00000527950.1
CRYAB
crystallin, alpha B
chr14_-_36789783 0.13 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MBIP
MAP3K12 binding inhibitory protein 1
chr9_-_39288092 0.13 ENST00000323947.7
ENST00000297668.6
ENST00000377656.2
ENST00000377659.1
CNTNAP3
contactin associated protein-like 3
chr2_-_230787879 0.13 ENST00000435716.1
TRIP12
thyroid hormone receptor interactor 12
chr2_-_119605253 0.13 ENST00000295206.6
EN1
engrailed homeobox 1
chr11_-_75017734 0.12 ENST00000532525.1
ARRB1
arrestin, beta 1
chr12_+_58138800 0.12 ENST00000547992.1
ENST00000552816.1
ENST00000547472.1
TSPAN31
tetraspanin 31
chr9_+_82188077 0.12 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr3_-_50649192 0.12 ENST00000443053.2
ENST00000348721.3
CISH
cytokine inducible SH2-containing protein
chr12_+_133757995 0.12 ENST00000536435.2
ENST00000228289.5
ENST00000541211.2
ENST00000500625.3
ENST00000539248.2
ENST00000542711.2
ENST00000536899.2
ENST00000542986.2
ENST00000537565.1
ENST00000541975.2
ZNF268
zinc finger protein 268
chr7_-_17598506 0.12 ENST00000451792.1
AC017060.1
AC017060.1
chr6_+_54173227 0.12 ENST00000259782.4
ENST00000370864.3
TINAG
tubulointerstitial nephritis antigen
chr4_+_187813673 0.12 ENST00000606881.1
RP11-11N5.3
RP11-11N5.3
chr14_-_58894332 0.11 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr7_+_73868439 0.11 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr11_+_72975578 0.11 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr22_-_30867973 0.11 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr1_+_11751748 0.11 ENST00000294485.5
DRAXIN
dorsal inhibitory axon guidance protein
chr2_-_61765315 0.11 ENST00000406957.1
ENST00000401558.2
XPO1
exportin 1 (CRM1 homolog, yeast)
chr4_+_129730947 0.11 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr3_-_98241358 0.11 ENST00000503004.1
ENST00000506575.1
ENST00000513452.1
ENST00000515620.1
CLDND1
claudin domain containing 1
chr15_+_43885252 0.11 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr2_+_55746722 0.11 ENST00000339012.3
CCDC104
coiled-coil domain containing 104
chr5_+_173316341 0.11 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr1_-_150208363 0.11 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_52604607 0.11 ENST00000551894.1
ENST00000553017.1
C12orf80
chromosome 12 open reading frame 80
chr4_+_129730839 0.11 ENST00000511647.1
PHF17
jade family PHD finger 1
chr14_-_83262540 0.11 ENST00000554451.1
RP11-11K13.1
RP11-11K13.1
chrM_+_10758 0.11 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr14_-_101034407 0.10 ENST00000443071.2
ENST00000557378.1
BEGAIN
brain-enriched guanylate kinase-associated
chr12_+_58138664 0.10 ENST00000257910.3
TSPAN31
tetraspanin 31
chr15_+_43985084 0.10 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr2_-_121223697 0.10 ENST00000593290.1
FLJ14816
long intergenic non-protein coding RNA 1101
chr2_-_14541060 0.10 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr5_-_149324306 0.10 ENST00000255266.5
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr9_-_95244781 0.10 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr1_-_53608249 0.10 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr6_-_35480640 0.10 ENST00000428978.1
ENST00000322263.4
TULP1
tubby like protein 1
chr19_+_2476116 0.10 ENST00000215631.4
ENST00000587345.1
GADD45B
growth arrest and DNA-damage-inducible, beta
chrX_+_123095860 0.10 ENST00000428941.1
STAG2
stromal antigen 2
chr10_-_62761188 0.10 ENST00000357917.4
RHOBTB1
Rho-related BTB domain containing 1
chr19_-_44124019 0.10 ENST00000300811.3
ZNF428
zinc finger protein 428
chr9_-_127358087 0.10 ENST00000475178.1
NR6A1
nuclear receptor subfamily 6, group A, member 1
chrM_+_9207 0.10 ENST00000362079.2
MT-CO3
mitochondrially encoded cytochrome c oxidase III
chr9_+_17135016 0.09 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr11_+_72975524 0.09 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr14_-_57197224 0.09 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr4_-_102268628 0.09 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_-_9291063 0.09 ENST00000383836.3
SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr4_+_110769258 0.09 ENST00000594814.1
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr7_+_28452130 0.09 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chrX_+_123095890 0.09 ENST00000435215.1
STAG2
stromal antigen 2
chr19_-_3479086 0.09 ENST00000587847.1
C19orf77
chromosome 19 open reading frame 77
chrM_+_8527 0.09 ENST00000361899.2
MT-ATP6
mitochondrially encoded ATP synthase 6
chr1_-_26633480 0.09 ENST00000450041.1
UBXN11
UBX domain protein 11
chr13_+_31191920 0.08 ENST00000255304.4
USPL1
ubiquitin specific peptidase like 1
chr9_+_17134980 0.08 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chr1_-_150208320 0.08 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr11_-_111783595 0.08 ENST00000528628.1
CRYAB
crystallin, alpha B
chr12_-_86650077 0.08 ENST00000552808.2
ENST00000547225.1
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_-_100485183 0.08 ENST00000394876.2
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr15_+_58430368 0.08 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr11_-_118436606 0.08 ENST00000530872.1
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr2_+_66662249 0.08 ENST00000560281.2
MEIS1
Meis homeobox 1
chr4_+_129730779 0.08 ENST00000226319.6
PHF17
jade family PHD finger 1
chr1_-_224033596 0.08 ENST00000391878.2
ENST00000343537.7
TP53BP2
tumor protein p53 binding protein, 2
chr11_+_111788738 0.08 ENST00000529342.1
C11orf52
chromosome 11 open reading frame 52
chr6_+_100054606 0.08 ENST00000369215.4
PRDM13
PR domain containing 13
chr6_-_31697563 0.07 ENST00000375789.2
ENST00000416410.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr3_+_111393501 0.07 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr3_+_63953415 0.07 ENST00000484332.1
ATXN7
ataxin 7
chr11_-_36619771 0.07 ENST00000311485.3
ENST00000527033.1
ENST00000532616.1
RAG2
recombination activating gene 2
chrX_-_6146876 0.07 ENST00000381095.3
NLGN4X
neuroligin 4, X-linked
chr3_-_48229846 0.07 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr2_+_120770645 0.07 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr1_-_151965048 0.07 ENST00000368809.1
S100A10
S100 calcium binding protein A10
chr2_+_170366203 0.07 ENST00000284669.1
KLHL41
kelch-like family member 41
chr10_-_48390973 0.07 ENST00000224600.4
RBP3
retinol binding protein 3, interstitial
chr2_-_188312971 0.07 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr18_-_21891460 0.07 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr12_-_110937351 0.07 ENST00000552130.2
VPS29
vacuolar protein sorting 29 homolog (S. cerevisiae)
chr5_-_95768973 0.07 ENST00000311106.3
PCSK1
proprotein convertase subtilisin/kexin type 1
chr3_-_149388682 0.07 ENST00000475579.1
WWTR1
WW domain containing transcription regulator 1
chr19_-_10121144 0.07 ENST00000264828.3
COL5A3
collagen, type V, alpha 3
chr17_-_46692287 0.07 ENST00000239144.4
HOXB8
homeobox B8
chr10_+_129785536 0.06 ENST00000419012.2
PTPRE
protein tyrosine phosphatase, receptor type, E
chr11_+_72975559 0.06 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr7_+_73868120 0.06 ENST00000265755.3
GTF2IRD1
GTF2I repeat domain containing 1
chr5_-_36301984 0.06 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr2_-_55237484 0.06 ENST00000394609.2
RTN4
reticulon 4
chr21_+_17443521 0.06 ENST00000456342.1
LINC00478
long intergenic non-protein coding RNA 478
chr19_+_40877583 0.06 ENST00000596470.1
PLD3
phospholipase D family, member 3
chr10_-_105845674 0.06 ENST00000353479.5
ENST00000369733.3
COL17A1
collagen, type XVII, alpha 1
chr6_-_31697255 0.06 ENST00000436437.1
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr4_-_100485143 0.06 ENST00000394877.3
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr1_+_180897269 0.06 ENST00000367587.1
KIAA1614
KIAA1614
chr8_+_42873548 0.06 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr10_-_74114714 0.06 ENST00000338820.3
ENST00000394903.2
ENST00000444643.2
DNAJB12
DnaJ (Hsp40) homolog, subfamily B, member 12
chr19_+_11457175 0.06 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chr14_-_71107921 0.06 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr14_-_22005197 0.05 ENST00000541965.1
SALL2
spalt-like transcription factor 2
chr22_-_41258074 0.05 ENST00000307221.4
DNAJB7
DnaJ (Hsp40) homolog, subfamily B, member 7
chr1_-_117664317 0.05 ENST00000256649.4
ENST00000369464.3
ENST00000485032.1
TRIM45
tripartite motif containing 45
chr12_+_6949964 0.05 ENST00000541978.1
ENST00000435982.2
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
chr17_-_43209862 0.05 ENST00000322765.5
PLCD3
phospholipase C, delta 3
chr18_-_35145593 0.05 ENST00000334919.5
ENST00000591282.1
ENST00000588597.1
CELF4
CUGBP, Elav-like family member 4
chr11_+_20044096 0.05 ENST00000533917.1
NAV2
neuron navigator 2
chr14_-_22005343 0.05 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr1_-_11751665 0.05 ENST00000376667.3
ENST00000235310.3
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr5_+_50679506 0.05 ENST00000511384.1
ISL1
ISL LIM homeobox 1
chrX_+_123097014 0.05 ENST00000394478.1
STAG2
stromal antigen 2
chr1_-_241799232 0.05 ENST00000366553.1
CHML
choroideremia-like (Rab escort protein 2)
chr1_+_18957500 0.05 ENST00000375375.3
PAX7
paired box 7
chr11_-_118436707 0.05 ENST00000264020.2
ENST00000264021.3
IFT46
intraflagellar transport 46 homolog (Chlamydomonas)
chr10_-_116418053 0.05 ENST00000277895.5
ABLIM1
actin binding LIM protein 1
chr10_+_95372289 0.05 ENST00000371447.3
PDE6C
phosphodiesterase 6C, cGMP-specific, cone, alpha prime
chr6_+_31554826 0.05 ENST00000376089.2
ENST00000396112.2
LST1
leukocyte specific transcript 1
chr7_-_111424462 0.05 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr10_+_95848824 0.05 ENST00000371385.3
ENST00000371375.1
PLCE1
phospholipase C, epsilon 1
chr10_+_118349920 0.05 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chr8_+_104892639 0.05 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr14_-_36789865 0.05 ENST00000416007.4
MBIP
MAP3K12 binding inhibitory protein 1
chr5_+_115358088 0.05 ENST00000600981.3
CTD-2287O16.3
CTD-2287O16.3
chr1_+_171939240 0.05 ENST00000523513.1
DNM3
dynamin 3
chr10_+_124895472 0.05 ENST00000357878.5
HMX3
H6 family homeobox 3
chr9_-_8857776 0.05 ENST00000481079.1
PTPRD
protein tyrosine phosphatase, receptor type, D
chr18_-_35145689 0.04 ENST00000591287.1
ENST00000601019.1
ENST00000601392.1
CELF4
CUGBP, Elav-like family member 4
chr17_-_39661849 0.04 ENST00000246635.3
ENST00000336861.3
ENST00000587544.1
ENST00000587435.1
KRT13
keratin 13
chr10_-_105845536 0.04 ENST00000393211.3
COL17A1
collagen, type XVII, alpha 1

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX2_CRX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.1 0.3 GO:2000426 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.2 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 0.5 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.0 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.0 0.4 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.0 0.1 GO:0048633 negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of mechanoreceptor differentiation(GO:0045632) positive regulation of skeletal muscle tissue growth(GO:0048633) negative regulation of inner ear receptor cell differentiation(GO:2000981)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:0061743 motor learning(GO:0061743)
0.0 0.9 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.1 GO:0046022 positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.0 0.2 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.3 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.0 0.6 GO:0014029 neural crest formation(GO:0014029)
0.0 0.1 GO:1903722 regulation of centriole elongation(GO:1903722)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.4 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.1 GO:1904823 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.1 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.8 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0071657 positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.6 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.0 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.0 0.2 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.1 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0010457 centriole-centriole cohesion(GO:0010457)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.8 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.5 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177)
0.0 0.0 GO:0098844 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.0 0.1 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.0 0.3 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0033165 interphotoreceptor matrix(GO:0033165)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222) intracellular cGMP activated cation channel activity(GO:0005223)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.2 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.0 0.3 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0005350 pyrimidine nucleobase transmembrane transporter activity(GO:0005350) glycerol channel activity(GO:0015254) urea channel activity(GO:0015265)
0.0 0.3 GO:0045029 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.9 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0032183 SUMO binding(GO:0032183)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME OPSINS Genes involved in Opsins
0.0 0.8 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors