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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for OTX1

Z-value: 1.36

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Transcription factors associated with OTX1

Gene Symbol Gene ID Gene Info
OTX1
ENSG00000115507.5 orthodenticle homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OTX1hg19_v2_chr2_+_63277927_632779380.425.8e-01Click!

Activity profile of OTX1 motif

Sorted Z-values of OTX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_67968793 2.29 ENST00000417488.1
RP11-195B21.3
Protein LOC644249
chr7_+_30589829 1.76 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr7_-_91509972 1.14 ENST00000425936.1
MTERF
mitochondrial transcription termination factor
chr1_+_241695424 0.99 ENST00000366558.3
ENST00000366559.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_241695670 0.95 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_-_160654745 0.73 ENST00000259053.4
ENST00000429078.2
CD302
CD302 molecule
chr12_+_100594557 0.71 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr4_-_122744998 0.69 ENST00000274026.5
CCNA2
cyclin A2
chr1_+_229440129 0.64 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr6_+_26204825 0.63 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr5_-_114631958 0.61 ENST00000395557.4
CCDC112
coiled-coil domain containing 112
chr2_+_102721023 0.60 ENST00000409589.1
ENST00000409329.1
IL1R1
interleukin 1 receptor, type I
chr13_-_43566301 0.60 ENST00000398762.3
ENST00000313640.7
ENST00000313624.7
EPSTI1
epithelial stromal interaction 1 (breast)
chr17_-_4689649 0.59 ENST00000441199.2
ENST00000416307.2
VMO1
vitelline membrane outer layer 1 homolog (chicken)
chr3_+_142315225 0.58 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chr12_-_71533055 0.56 ENST00000552128.1
TSPAN8
tetraspanin 8
chr20_+_48884002 0.55 ENST00000425497.1
ENST00000445003.1
RP11-290F20.3
RP11-290F20.3
chr1_+_63989004 0.54 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr19_-_16008880 0.54 ENST00000011989.7
ENST00000221700.6
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr15_-_55657428 0.54 ENST00000568543.1
CCPG1
cell cycle progression 1
chr1_+_17531614 0.54 ENST00000375471.4
PADI1
peptidyl arginine deiminase, type I
chr22_-_39052300 0.53 ENST00000355830.6
FAM227A
family with sequence similarity 227, member A
chr15_+_58702742 0.50 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr8_+_109455830 0.49 ENST00000524143.1
EMC2
ER membrane protein complex subunit 2
chr1_+_184020830 0.47 ENST00000533373.1
ENST00000423085.2
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr1_+_221054411 0.43 ENST00000427693.1
HLX
H2.0-like homeobox
chr12_+_49740700 0.43 ENST00000549441.2
ENST00000395069.3
DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr14_+_50234309 0.42 ENST00000298307.5
KLHDC2
kelch domain containing 2
chr14_-_102552659 0.42 ENST00000441629.2
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr5_-_154230130 0.42 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr1_+_117910047 0.42 ENST00000356554.3
MAN1A2
mannosidase, alpha, class 1A, member 2
chr12_-_14956396 0.41 ENST00000535328.1
ENST00000261167.2
WBP11
WW domain binding protein 11
chr1_+_196621002 0.40 ENST00000367429.4
ENST00000439155.2
CFH
complement factor H
chr2_-_14541060 0.38 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr6_+_26158343 0.38 ENST00000377777.4
ENST00000289316.2
HIST1H2BD
histone cluster 1, H2bd
chr12_+_6603253 0.38 ENST00000382457.4
ENST00000545962.1
NCAPD2
non-SMC condensin I complex, subunit D2
chr5_-_54988448 0.37 ENST00000503817.1
ENST00000512595.1
SLC38A9
solute carrier family 38, member 9
chr5_+_96038476 0.35 ENST00000511049.1
ENST00000309190.5
ENST00000510156.1
ENST00000509903.1
ENST00000511782.1
ENST00000504465.1
CAST
calpastatin
chr2_+_122513109 0.35 ENST00000389682.3
ENST00000536142.1
TSN
translin
chr7_-_91509986 0.34 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF
mitochondrial transcription termination factor
chr21_+_17214724 0.32 ENST00000449491.1
USP25
ubiquitin specific peptidase 25
chr8_-_56986768 0.31 ENST00000523936.1
RPS20
ribosomal protein S20
chr16_-_29875057 0.31 ENST00000219789.6
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr22_-_36903101 0.31 ENST00000397224.4
FOXRED2
FAD-dependent oxidoreductase domain containing 2
chr10_-_115423792 0.31 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
NRAP
nebulin-related anchoring protein
chr14_-_89878369 0.31 ENST00000553840.1
ENST00000556916.1
FOXN3
forkhead box N3
chr1_+_40723779 0.31 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr3_+_142315294 0.31 ENST00000464320.1
PLS1
plastin 1
chr1_+_184020811 0.30 ENST00000361641.1
TSEN15
TSEN15 tRNA splicing endonuclease subunit
chr8_+_38244638 0.30 ENST00000526356.1
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr12_-_54071181 0.30 ENST00000338662.5
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr4_+_100737954 0.30 ENST00000296414.7
ENST00000512369.1
DAPP1
dual adaptor of phosphotyrosine and 3-phosphoinositides
chr5_+_96038554 0.30 ENST00000508197.1
CAST
calpastatin
chr16_-_57880439 0.29 ENST00000565684.1
KIFC3
kinesin family member C3
chr11_+_119205222 0.27 ENST00000311413.4
RNF26
ring finger protein 26
chr16_-_29874462 0.27 ENST00000566113.1
ENST00000569956.1
ENST00000570016.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr14_-_27066636 0.26 ENST00000267422.7
ENST00000344429.5
ENST00000574031.1
ENST00000465357.2
ENST00000547619.1
NOVA1
neuro-oncological ventral antigen 1
chr12_-_107380846 0.25 ENST00000548101.1
ENST00000550496.1
ENST00000552029.1
MTERFD3
MTERF domain containing 3
chr11_-_78052923 0.25 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr12_+_124997766 0.25 ENST00000543970.1
RP11-83B20.1
RP11-83B20.1
chr1_+_87458692 0.24 ENST00000370548.2
ENST00000356813.4
RP5-1052I5.2
HS2ST1
Heparan sulfate 2-O-sulfotransferase 1
heparan sulfate 2-O-sulfotransferase 1
chr9_+_128509624 0.24 ENST00000342287.5
ENST00000373487.4
PBX3
pre-B-cell leukemia homeobox 3
chr11_-_67210930 0.24 ENST00000453768.2
ENST00000545016.1
ENST00000341356.5
CORO1B
coronin, actin binding protein, 1B
chr6_+_147981838 0.24 ENST00000427015.1
ENST00000432506.1
RP11-307P5.1
RP11-307P5.1
chr1_-_206288647 0.23 ENST00000331555.5
C1orf186
chromosome 1 open reading frame 186
chr1_-_146696901 0.23 ENST00000369272.3
ENST00000441068.2
FMO5
flavin containing monooxygenase 5
chr8_+_22132847 0.23 ENST00000521356.1
PIWIL2
piwi-like RNA-mediated gene silencing 2
chr9_-_35665165 0.23 ENST00000343259.3
ENST00000378387.3
ARHGEF39
Rho guanine nucleotide exchange factor (GEF) 39
chr1_-_161039753 0.22 ENST00000368015.1
ARHGAP30
Rho GTPase activating protein 30
chr6_-_41039567 0.22 ENST00000468811.1
OARD1
O-acyl-ADP-ribose deacylase 1
chrX_+_133507283 0.22 ENST00000370803.3
PHF6
PHD finger protein 6
chr17_-_79623597 0.22 ENST00000574024.1
ENST00000331056.5
PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr1_-_26372602 0.21 ENST00000374278.3
ENST00000374276.3
SLC30A2
solute carrier family 30 (zinc transporter), member 2
chr9_-_113761720 0.21 ENST00000541779.1
ENST00000374430.2
LPAR1
lysophosphatidic acid receptor 1
chr1_-_92351769 0.21 ENST00000212355.4
TGFBR3
transforming growth factor, beta receptor III
chr4_-_112993808 0.21 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr19_+_47616682 0.21 ENST00000594526.1
SAE1
SUMO1 activating enzyme subunit 1
chr3_-_69062790 0.21 ENST00000540955.1
ENST00000456376.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr1_-_89458604 0.20 ENST00000260508.4
CCBL2
cysteine conjugate-beta lyase 2
chr2_-_112642267 0.20 ENST00000341068.3
ANAPC1
anaphase promoting complex subunit 1
chr2_-_211090162 0.19 ENST00000233710.3
ACADL
acyl-CoA dehydrogenase, long chain
chr3_+_42544084 0.19 ENST00000543411.1
ENST00000438259.2
ENST00000439731.1
ENST00000325123.4
VIPR1
vasoactive intestinal peptide receptor 1
chr8_-_125577940 0.19 ENST00000519168.1
ENST00000395508.2
MTSS1
metastasis suppressor 1
chr16_-_29874211 0.19 ENST00000563415.1
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr9_-_95298314 0.18 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr6_+_26251835 0.18 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr8_+_35649365 0.18 ENST00000437887.1
AC012215.1
Uncharacterized protein
chrX_-_48937684 0.18 ENST00000465382.1
ENST00000423215.2
WDR45
WD repeat domain 45
chr9_-_95244781 0.17 ENST00000375544.3
ENST00000375543.1
ENST00000395538.3
ENST00000450139.2
ASPN
asporin
chr5_+_59783540 0.17 ENST00000515734.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr4_-_83769996 0.17 ENST00000511338.1
SEC31A
SEC31 homolog A (S. cerevisiae)
chr9_+_91605778 0.17 ENST00000375851.2
ENST00000375850.3
ENST00000334490.5
C9orf47
chromosome 9 open reading frame 47
chr19_+_10531150 0.16 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_+_130029457 0.16 ENST00000278742.5
ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr7_+_16700806 0.16 ENST00000446596.1
ENST00000438834.1
BZW2
basic leucine zipper and W2 domains 2
chr2_+_109403193 0.16 ENST00000412964.2
ENST00000295124.4
CCDC138
coiled-coil domain containing 138
chr22_+_39052632 0.16 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr13_+_24825824 0.16 ENST00000434675.1
ENST00000494772.1
SPATA13
spermatogenesis associated 13
chr11_-_102962874 0.15 ENST00000531543.1
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5
chr9_-_100935043 0.15 ENST00000343933.5
CORO2A
coronin, actin binding protein, 2A
chr1_+_81771806 0.15 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr7_+_55980331 0.15 ENST00000429591.2
ZNF713
zinc finger protein 713
chr11_-_104817919 0.15 ENST00000533252.1
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr8_-_33370607 0.15 ENST00000360742.5
ENST00000523305.1
TTI2
TELO2 interacting protein 2
chrX_-_100307043 0.14 ENST00000372939.1
ENST00000372935.1
ENST00000372936.3
TRMT2B
tRNA methyltransferase 2 homolog B (S. cerevisiae)
chr6_-_131211534 0.14 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr19_-_36001286 0.14 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN
dermokine
chr8_+_80209929 0.14 ENST00000519983.1
RP11-1114I9.1
RP11-1114I9.1
chr6_+_33359582 0.14 ENST00000450504.1
KIFC1
kinesin family member C1
chr5_-_54603368 0.14 ENST00000508346.1
ENST00000251636.5
DHX29
DEAH (Asp-Glu-Ala-His) box polypeptide 29
chr3_+_195447738 0.14 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr1_+_28764653 0.13 ENST00000373836.3
PHACTR4
phosphatase and actin regulator 4
chr14_-_80697396 0.13 ENST00000557010.1
DIO2
deiodinase, iodothyronine, type II
chr1_-_53608249 0.13 ENST00000371494.4
SLC1A7
solute carrier family 1 (glutamate transporter), member 7
chr5_+_135496675 0.13 ENST00000507637.1
SMAD5
SMAD family member 5
chr18_-_59274139 0.13 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr15_+_42787452 0.12 ENST00000249647.3
SNAP23
synaptosomal-associated protein, 23kDa
chr3_+_58223228 0.12 ENST00000478253.1
ENST00000295962.4
ABHD6
abhydrolase domain containing 6
chr12_+_20963647 0.12 ENST00000381545.3
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr7_-_100239132 0.11 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr2_-_85637459 0.11 ENST00000409921.1
CAPG
capping protein (actin filament), gelsolin-like
chr10_+_114133773 0.11 ENST00000354655.4
ACSL5
acyl-CoA synthetase long-chain family member 5
chr8_-_79717750 0.11 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr2_-_61389168 0.10 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1
RP11-493E12.1
chr16_-_66583701 0.10 ENST00000527800.1
ENST00000525974.1
ENST00000563369.2
TK2
thymidine kinase 2, mitochondrial
chr14_+_102196739 0.10 ENST00000556973.1
RP11-796G6.2
Uncharacterized protein
chr17_-_34329084 0.10 ENST00000354059.4
ENST00000536149.1
CCL15
CCL14
chemokine (C-C motif) ligand 15
chemokine (C-C motif) ligand 14
chrX_+_149861836 0.10 ENST00000542156.1
ENST00000370390.3
ENST00000490316.2
ENST00000445323.2
ENST00000544228.1
ENST00000451863.2
MTMR1
myotubularin related protein 1
chr1_-_154928562 0.10 ENST00000368463.3
ENST00000539880.1
ENST00000542459.1
ENST00000368460.3
ENST00000368465.1
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr10_+_52724028 0.10 ENST00000561565.1
RP11-96B5.4
RP11-96B5.4
chr13_+_38923959 0.10 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr4_+_76439095 0.10 ENST00000506261.1
THAP6
THAP domain containing 6
chr2_+_201936707 0.10 ENST00000433898.1
ENST00000454214.1
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chrX_-_109561294 0.10 ENST00000372059.2
ENST00000262844.5
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr14_-_27066960 0.10 ENST00000539517.2
NOVA1
neuro-oncological ventral antigen 1
chr17_+_56769924 0.09 ENST00000461271.1
ENST00000583539.1
ENST00000337432.4
ENST00000421782.2
RAD51C
RAD51 paralog C
chr16_-_69373396 0.09 ENST00000562595.1
ENST00000562081.1
ENST00000306875.4
COG8
component of oligomeric golgi complex 8
chr16_-_21452040 0.09 ENST00000521589.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr5_+_59783941 0.08 ENST00000506884.1
ENST00000504876.2
PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr3_-_12587055 0.08 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr1_+_45805342 0.08 ENST00000372090.5
TOE1
target of EGR1, member 1 (nuclear)
chr7_+_99195878 0.08 ENST00000453227.1
ENST00000429679.1
GS1-259H13.2
GS1-259H13.2
chr12_+_20963632 0.08 ENST00000540853.1
ENST00000261196.2
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr14_+_21458127 0.08 ENST00000382985.4
ENST00000556670.2
ENST00000553564.1
ENST00000554751.1
ENST00000554283.1
ENST00000555670.1
METTL17
methyltransferase like 17
chr12_-_107380910 0.07 ENST00000392830.2
ENST00000240050.4
MTERFD3
MTERF domain containing 3
chr2_+_232135245 0.07 ENST00000446447.1
ARMC9
armadillo repeat containing 9
chr6_+_96025341 0.07 ENST00000369293.1
ENST00000358812.4
MANEA
mannosidase, endo-alpha
chr22_-_28316116 0.07 ENST00000415296.1
PITPNB
phosphatidylinositol transfer protein, beta
chr16_-_58163262 0.07 ENST00000565880.1
C16orf80
chromosome 16 open reading frame 80
chr6_+_150070857 0.06 ENST00000544496.1
PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr6_+_151186554 0.06 ENST00000367321.3
ENST00000367307.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr2_+_234580525 0.06 ENST00000609637.1
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_+_183815318 0.06 ENST00000425359.2
HTR3E
5-hydroxytryptamine (serotonin) receptor 3E, ionotropic
chr3_+_138340067 0.06 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr8_+_65492756 0.06 ENST00000321870.1
BHLHE22
basic helix-loop-helix family, member e22
chr1_-_166944561 0.05 ENST00000271417.3
ILDR2
immunoglobulin-like domain containing receptor 2
chr3_-_69062742 0.05 ENST00000424374.1
EOGT
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr19_-_12941469 0.05 ENST00000586969.1
ENST00000589681.1
ENST00000585384.1
ENST00000589808.1
RTBDN
retbindin
chr19_+_16308659 0.05 ENST00000590263.1
ENST00000590756.1
ENST00000541844.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr17_-_36981556 0.05 ENST00000536127.1
ENST00000225428.5
CWC25
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr2_+_234580499 0.05 ENST00000354728.4
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr1_+_178310581 0.05 ENST00000462775.1
RASAL2
RAS protein activator like 2
chrX_+_53123314 0.04 ENST00000605526.1
ENST00000604062.1
ENST00000604369.1
ENST00000366185.2
ENST00000604849.1
RP11-258C19.5
long intergenic non-protein coding RNA 1155
chr9_+_116172958 0.04 ENST00000374165.1
C9orf43
chromosome 9 open reading frame 43
chr3_+_111393501 0.04 ENST00000393934.3
PLCXD2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr3_+_136649311 0.04 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr11_-_85376121 0.04 ENST00000527447.1
CREBZF
CREB/ATF bZIP transcription factor
chr6_+_42018614 0.03 ENST00000465926.1
ENST00000482432.1
TAF8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr2_-_234475380 0.03 ENST00000443711.2
ENST00000251722.6
USP40
ubiquitin specific peptidase 40
chr2_+_204103663 0.03 ENST00000356079.4
ENST00000429815.2
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chrX_-_43832711 0.02 ENST00000378062.5
NDP
Norrie disease (pseudoglioma)
chr20_-_33539655 0.02 ENST00000451957.2
GSS
glutathione synthetase
chr4_+_22999152 0.02 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr2_+_170335924 0.02 ENST00000554017.1
ENST00000392663.2
ENST00000513963.1
BBS5
RP11-724O16.1
Bardet-Biedl syndrome 5
Bardet-Biedl syndrome 5 protein; Uncharacterized protein
chr3_-_52002403 0.02 ENST00000490063.1
ENST00000468324.1
ENST00000497653.1
ENST00000484633.1
PCBP4
poly(rC) binding protein 4
chr9_-_116172946 0.02 ENST00000374171.4
POLE3
polymerase (DNA directed), epsilon 3, accessory subunit
chr3_-_52002194 0.02 ENST00000466412.1
PCBP4
poly(rC) binding protein 4
chr16_-_69448 0.02 ENST00000326592.9
WASH4P
WAS protein family homolog 4 pseudogene
chr1_-_151300160 0.01 ENST00000368874.4
PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr14_-_102706934 0.01 ENST00000523231.1
ENST00000524370.1
ENST00000517966.1
MOK
MOK protein kinase
chr18_+_8717369 0.01 ENST00000359865.3
ENST00000400050.3
ENST00000306285.7
SOGA2
SOGA family member 2
chr1_+_222913009 0.01 ENST00000456298.1
FAM177B
family with sequence similarity 177, member B
chr12_-_11214893 0.01 ENST00000533467.1
TAS2R46
taste receptor, type 2, member 46
chr4_+_108815402 0.01 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr1_+_170501270 0.01 ENST00000367763.3
ENST00000367762.1
GORAB
golgin, RAB6-interacting
chr16_-_15950868 0.01 ENST00000396324.3
ENST00000452625.2
ENST00000576790.2
ENST00000300036.5
MYH11
myosin, heavy chain 11, smooth muscle
chr10_-_50122277 0.00 ENST00000374160.3
LRRC18
leucine rich repeat containing 18
chr19_+_16308711 0.00 ENST00000429941.2
ENST00000444449.2
ENST00000589822.1
AP1M1
adaptor-related protein complex 1, mu 1 subunit
chr20_-_3140490 0.00 ENST00000449731.1
ENST00000380266.3
UBOX5
FASTKD5
U-box domain containing 5
FAST kinase domains 5
chr15_-_80695917 0.00 ENST00000559008.1
RP11-210M15.2
Uncharacterized protein
chr7_+_120702819 0.00 ENST00000423795.1
CPED1
cadherin-like and PC-esterase domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of OTX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.2 0.7 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
0.2 0.5 GO:0003095 pressure natriuresis(GO:0003095)
0.1 0.9 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.5 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.3 GO:0080120 prenylated protein catabolic process(GO:0030327) CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.5 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.4 GO:0043335 protein unfolding(GO:0043335)
0.1 0.2 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.1 0.2 GO:1902463 protein localization to cell leading edge(GO:1902463)
0.1 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.2 GO:0034699 response to luteinizing hormone(GO:0034699)
0.1 0.2 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.1 0.4 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.4 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.2 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.8 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.6 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.8 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035) epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.3 GO:0006875 cellular metal ion homeostasis(GO:0006875)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.4 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.0 0.1 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.3 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.0 0.1 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.0 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 0.4 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.2 GO:1990923 PET complex(GO:1990923)
0.1 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:0070993 translation preinitiation complex(GO:0070993)
0.0 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0071682 endocytic vesicle lumen(GO:0071682)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.2 0.5 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.2 1.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.1 0.8 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.6 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.3 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.1 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0070123 transforming growth factor beta receptor activity, type III(GO:0070123)
0.1 0.2 GO:0019948 SUMO activating enzyme activity(GO:0019948)
0.1 0.2 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.2 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.5 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.1 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.4 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts