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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for OLIG2_NEUROD1_ATOH1

Z-value: 1.21

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Transcription factors associated with OLIG2_NEUROD1_ATOH1

Gene Symbol Gene ID Gene Info
ENSG00000205927.4 oligodendrocyte transcription factor 2
ENSG00000162992.3 neuronal differentiation 1
ENSG00000172238.3 atonal bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
OLIG2hg19_v2_chr21_+_34398153_34398250-0.703.0e-01Click!
NEUROD1hg19_v2_chr2_-_182545603_182545603-0.613.9e-01Click!

Activity profile of OLIG2_NEUROD1_ATOH1 motif

Sorted Z-values of OLIG2_NEUROD1_ATOH1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr22_-_21905120 0.91 ENST00000331505.5
RIMS binding protein 3C
chr8_-_135522425 0.79 ENST00000521673.1
zinc finger and AT hook domain containing
chr8_-_123706338 0.68 ENST00000521608.1
long intergenic non-protein coding RNA 1151
chr19_-_38743878 0.64 ENST00000587515.1
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr5_+_71475449 0.62 ENST00000504492.1
microtubule-associated protein 1B
chr2_-_154335300 0.62 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr6_-_26250835 0.57 ENST00000446824.2
histone cluster 1, H3f
chr12_-_58145889 0.53 ENST00000547853.1
cyclin-dependent kinase 4
chr4_-_24914576 0.49 ENST00000502801.1
ENST00000428116.2
coiled-coil domain containing 149
chrX_+_118108571 0.48 ENST00000304778.7
LON peptidase N-terminal domain and ring finger 3
chr3_+_49840685 0.47 ENST00000333323.4
family with sequence similarity 212, member A
chr5_-_180632147 0.45 ENST00000274773.7
tripartite motif containing 7
chr16_+_72142195 0.44 ENST00000563819.1
ENST00000567142.2
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chrX_+_118108601 0.38 ENST00000371628.3
LON peptidase N-terminal domain and ring finger 3
chr20_-_31124186 0.37 ENST00000375678.3
chromosome 20 open reading frame 112
chr11_-_64764435 0.36 ENST00000534177.1
ENST00000301887.4
basic leucine zipper transcription factor, ATF-like 2
chr16_+_57438679 0.35 ENST00000219244.4
chemokine (C-C motif) ligand 17
chr2_-_183387064 0.34 ENST00000536095.1
ENST00000331935.6
ENST00000358139.2
ENST00000456212.1
phosphodiesterase 1A, calmodulin-dependent
chr19_+_45204630 0.34 ENST00000405314.2
carcinoembryonic antigen-related cell adhesion molecule 16
chr3_-_52486841 0.33 ENST00000496590.1
troponin C type 1 (slow)
chr10_-_73848531 0.32 ENST00000373109.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr19_+_17416457 0.32 ENST00000252602.1
mitochondrial ribosomal protein L34
chr16_+_4606347 0.31 ENST00000444310.4
chromosome 16 open reading frame 96
chr12_+_113416191 0.31 ENST00000342315.4
ENST00000392583.2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr8_+_39972170 0.31 ENST00000521257.1
RP11-359E19.2
chr17_-_37009882 0.30 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
ribosomal protein L23
chr12_+_56415100 0.30 ENST00000547791.1
IKAROS family zinc finger 4 (Eos)
chr19_+_17416609 0.30 ENST00000602206.1
mitochondrial ribosomal protein L34
chr8_-_49833978 0.30 ENST00000020945.1
snail family zinc finger 2
chr21_-_16135411 0.30 ENST00000435315.2
AF127936.5
chr10_-_13043697 0.29 ENST00000378825.3
coiled-coil domain containing 3
chrX_-_73512411 0.28 ENST00000602576.1
ENST00000429124.1
FTX transcript, XIST regulator (non-protein coding)
chr3_-_52869205 0.28 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr7_-_150777920 0.27 ENST00000353841.2
ENST00000297532.6
Fas-activated serine/threonine kinase
chr12_+_94551874 0.27 ENST00000551850.1
plexin C1
chr22_-_42342692 0.27 ENST00000404067.1
ENST00000402338.1
centromere protein M
chr18_+_59415396 0.27 ENST00000567801.1
RP11-1096D5.1
chr2_-_163100045 0.26 ENST00000188790.4
fibroblast activation protein, alpha
chr2_-_7005785 0.26 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chrX_-_108868390 0.26 ENST00000372101.2
KCNE1-like
chr7_-_150777949 0.26 ENST00000482571.1
Fas-activated serine/threonine kinase
chr16_+_83932684 0.25 ENST00000262430.4
malonyl-CoA decarboxylase
chr19_-_6501778 0.25 ENST00000596291.1
tubulin, beta 4A class IVa
chr11_+_66115304 0.25 ENST00000531602.1
Uncharacterized protein
chr19_+_19030497 0.24 ENST00000438170.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr17_+_74380683 0.24 ENST00000592299.1
ENST00000590959.1
ENST00000323374.4
sphingosine kinase 1
chr1_-_226111929 0.24 ENST00000343818.6
ENST00000432920.2
pyrroline-5-carboxylate reductase family, member 2
Uncharacterized protein
chr17_-_74722672 0.23 ENST00000397625.4
ENST00000445478.2
jumonji domain containing 6
chr7_-_150777874 0.23 ENST00000540185.1
Fas-activated serine/threonine kinase
chr6_+_53948328 0.22 ENST00000370876.2
muscular LMNA-interacting protein
chr12_-_49318715 0.21 ENST00000444214.2
FK506 binding protein 11, 19 kDa
chr17_-_41132010 0.21 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1 readthrough
chr12_+_6309963 0.21 ENST00000382515.2
CD9 molecule
chr2_+_7005959 0.21 ENST00000442639.1
radical S-adenosyl methionine domain containing 2
chr2_-_42160486 0.21 ENST00000427054.1
AC104654.2
chr8_-_49834299 0.20 ENST00000396822.1
snail family zinc finger 2
chr2_-_220117867 0.20 ENST00000456818.1
ENST00000447205.1
tubulin, alpha 4a
chr11_+_76494253 0.20 ENST00000333090.4
tsukushi, small leucine rich proteoglycan
chr15_+_75940218 0.20 ENST00000308527.5
sorting nexin 33
chrX_+_150565038 0.20 ENST00000370361.1
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr15_-_75660919 0.20 ENST00000569482.1
ENST00000565683.1
ENST00000561615.1
ENST00000563622.1
ENST00000568374.1
ENST00000566256.1
ENST00000267978.5
mannosidase, alpha, class 2C, member 1
chr9_+_131174024 0.20 ENST00000420034.1
ENST00000372842.1
cerebral endothelial cell adhesion molecule
chr12_+_4382917 0.19 ENST00000261254.3
cyclin D2
chr17_-_7216939 0.19 ENST00000573684.1
G protein pathway suppressor 2
chr11_+_118826999 0.19 ENST00000264031.2
uroplakin 2
chr1_-_201346761 0.19 ENST00000455702.1
ENST00000422165.1
ENST00000367318.5
ENST00000367320.2
ENST00000438742.1
ENST00000412633.1
ENST00000458432.2
ENST00000421663.2
ENST00000367322.1
ENST00000509001.1
troponin T type 2 (cardiac)
chr16_+_57847684 0.19 ENST00000335616.2
uncharacterized protein LOC388282
chr17_-_74722536 0.19 ENST00000585429.1
jumonji domain containing 6
chr8_-_41522779 0.19 ENST00000522231.1
ENST00000314214.8
ENST00000348036.4
ENST00000457297.1
ENST00000522543.1
ankyrin 1, erythrocytic
chrX_-_73512177 0.19 ENST00000603672.1
ENST00000418855.1
FTX transcript, XIST regulator (non-protein coding)
chr15_+_67547113 0.18 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQ motif containing H
chr1_-_209792111 0.18 ENST00000455193.1
laminin, beta 3
chrX_+_70521584 0.18 ENST00000373829.3
ENST00000538820.1
integrin beta 1 binding protein (melusin) 2
chr14_+_24584508 0.18 ENST00000559354.1
ENST00000560459.1
ENST00000559593.1
ENST00000396941.4
ENST00000396936.1
DDB1 and CUL4 associated factor 11
chr19_-_19030157 0.18 ENST00000349893.4
ENST00000351079.4
ENST00000600932.1
ENST00000262812.4
coatomer protein complex, subunit epsilon
chr7_+_30174668 0.18 ENST00000415604.1
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr1_-_226076843 0.18 ENST00000272134.5
left-right determination factor 1
chr7_+_5229819 0.18 ENST00000288828.4
ENST00000401525.3
ENST00000404704.3
WD repeat domain, phosphoinositide interacting 2
chr1_+_180165672 0.18 ENST00000443059.1
quiescin Q6 sulfhydryl oxidase 1
chr8_-_6914251 0.18 ENST00000330590.2
defensin, alpha 5, Paneth cell-specific
chr19_-_17010360 0.17 ENST00000599287.2
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr17_+_49243176 0.17 ENST00000513177.1
NME1-NME2 readthrough
chr19_-_13068012 0.17 ENST00000316939.1
growth arrest and DNA-damage-inducible, gamma interacting protein 1
chr9_+_116298778 0.17 ENST00000462143.1
regulator of G-protein signaling 3
chr19_+_19030478 0.17 ENST00000247003.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
chr11_-_57417367 0.17 ENST00000534810.1
yippee-like 4 (Drosophila)
chr11_+_46299199 0.17 ENST00000529193.1
ENST00000288400.3
cAMP responsive element binding protein 3-like 1
chr12_+_79371565 0.16 ENST00000551304.1
synaptotagmin I
chr3_-_10332416 0.16 ENST00000450603.1
ENST00000449554.2
ghrelin/obestatin prepropeptide
chr12_-_52715179 0.16 ENST00000293670.3
keratin 83
chr11_+_65029233 0.16 ENST00000265465.3
polymerase (DNA directed), alpha 2, accessory subunit
chr19_+_36249057 0.16 ENST00000301165.5
ENST00000536950.1
ENST00000537459.1
ENST00000421853.2
chromosome 19 open reading frame 55
chr7_+_143078652 0.16 ENST00000354434.4
ENST00000449423.2
zyxin
chr18_+_43753500 0.16 ENST00000587591.1
ENST00000588730.1
chromosome 18 open reading frame 25
chr14_-_75078725 0.16 ENST00000556690.1
latent transforming growth factor beta binding protein 2
chr1_-_154842741 0.16 ENST00000271915.4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr12_+_58176525 0.16 ENST00000543727.1
ENST00000540550.1
ENST00000323833.8
ENST00000350762.5
ENST00000550559.1
ENST00000548851.1
ENST00000434359.1
ENST00000457189.1
Ts translation elongation factor, mitochondrial
chr17_+_74381343 0.16 ENST00000392496.3
sphingosine kinase 1
chr11_+_45918092 0.16 ENST00000395629.2
mitogen-activated protein kinase 8 interacting protein 1
chr17_+_40925454 0.15 ENST00000253794.2
ENST00000590339.1
ENST00000589520.1
vacuolar protein sorting 25 homolog (S. cerevisiae)
chr19_-_42916499 0.15 ENST00000601189.1
ENST00000599211.1
lipase, hormone-sensitive
chr3_-_101039402 0.15 ENST00000193391.7
interphotoreceptor matrix proteoglycan 2
chr9_+_140033862 0.15 ENST00000350902.5
ENST00000371550.4
ENST00000371546.4
ENST00000371555.4
ENST00000371553.3
ENST00000371559.4
ENST00000371560.3
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr19_+_16186903 0.15 ENST00000588507.1
tropomyosin 4
chr12_+_57849048 0.15 ENST00000266646.2
inhibin, beta E
chr6_-_112194484 0.15 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN oncogene related to SRC, FGR, YES
chr17_-_56492989 0.15 ENST00000583753.1
ring finger protein 43
chr6_-_42690312 0.15 ENST00000230381.5
peripherin 2 (retinal degeneration, slow)
chr3_-_71774516 0.15 ENST00000425534.3
eukaryotic translation initiation factor 4E family member 3
chr18_+_77439775 0.15 ENST00000299543.7
ENST00000075430.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr7_-_41742697 0.15 ENST00000242208.4
inhibin, beta A
chr17_-_76713100 0.15 ENST00000585509.1
cytohesin 1
chr12_-_130529501 0.15 ENST00000561864.1
ENST00000567788.1
RP11-474D1.4
RP11-474D1.3
chr2_-_61389240 0.15 ENST00000606876.1
RP11-493E12.1
chr12_-_58146048 0.15 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
cyclin-dependent kinase 4
chr12_-_58145604 0.14 ENST00000552254.1
cyclin-dependent kinase 4
chr5_+_135364584 0.14 ENST00000442011.2
ENST00000305126.8
transforming growth factor, beta-induced, 68kDa
chr2_-_225811747 0.14 ENST00000409592.3
dedicator of cytokinesis 10
chrX_+_69509927 0.14 ENST00000374403.3
kinesin family member 4A
chr12_+_104458235 0.14 ENST00000229330.4
host cell factor C2
chr18_+_18943554 0.14 ENST00000580732.2
growth regulation by estrogen in breast cancer-like
chr17_-_41132410 0.14 ENST00000409446.3
ENST00000453594.1
ENST00000409399.1
ENST00000421990.2
prostaglandin E synthase 3 (cytosolic)-like
PTGES3L-AARSD1 readthrough
chr19_-_6057282 0.14 ENST00000592281.1
regulatory factor X, 2 (influences HLA class II expression)
chr9_-_139760717 0.14 ENST00000371648.4
endothelial differentiation-related factor 1
chr10_-_73848764 0.14 ENST00000317376.4
ENST00000412663.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr5_+_39520499 0.13 ENST00000604954.1
CTD-2078B5.2
chr1_-_24469602 0.13 ENST00000270800.1
interleukin 22 receptor, alpha 1
chr2_+_65215604 0.13 ENST00000531327.1
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr19_+_18111927 0.13 ENST00000379656.3
arrestin domain containing 2
chr2_-_74779744 0.13 ENST00000409249.1
lysyl oxidase-like 3
chr12_+_48152774 0.13 ENST00000549243.1
solute carrier family 48 (heme transporter), member 1
chr8_-_128231299 0.13 ENST00000500112.1
colon cancer associated transcript 1 (non-protein coding)
chr5_+_156887027 0.13 ENST00000435489.2
ENST00000311946.7
NIPA-like domain containing 4
chr2_+_220325441 0.13 ENST00000396688.1
SPEG complex locus
chr22_-_50964558 0.13 ENST00000535425.1
ENST00000439934.1
SCO2 cytochrome c oxidase assembly protein
chr14_+_52313833 0.13 ENST00000553560.1
guanine nucleotide binding protein (G protein), gamma 2
chrX_+_37765364 0.13 ENST00000567273.1
AL121578.2
chr7_+_143079000 0.13 ENST00000392910.2
zyxin
chr19_-_4454081 0.13 ENST00000591919.1
UBX domain protein 6
chr9_-_139760737 0.13 ENST00000371649.1
ENST00000224073.1
endothelial differentiation-related factor 1
chr11_-_65625014 0.13 ENST00000534784.1
cofilin 1 (non-muscle)
chr1_+_110026544 0.13 ENST00000369870.3
ataxin 7-like 2
chr3_+_54157480 0.13 ENST00000490478.1
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr4_-_41216492 0.13 ENST00000503503.1
ENST00000509446.1
ENST00000503264.1
ENST00000508707.1
ENST00000508593.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr5_+_154181816 0.12 ENST00000518677.1
La ribonucleoprotein domain family, member 1
chr11_-_130298888 0.12 ENST00000257359.6
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr4_-_174451370 0.12 ENST00000359562.4
heart and neural crest derivatives expressed 2
chr2_-_27603582 0.12 ENST00000323703.6
ENST00000436006.1
zinc finger protein 513
chr11_-_47616210 0.12 ENST00000302514.3
C1q and tumor necrosis factor related protein 4
chr8_+_81398444 0.12 ENST00000455036.3
ENST00000426744.2
zinc finger and BTB domain containing 10
chr12_-_58146128 0.12 ENST00000551800.1
ENST00000549606.1
ENST00000257904.6
cyclin-dependent kinase 4
chr19_+_35521699 0.12 ENST00000415950.3
sodium channel, voltage-gated, type I, beta subunit
chr20_-_45061695 0.12 ENST00000445496.2
engulfment and cell motility 2
chr10_-_8095412 0.12 ENST00000458727.1
ENST00000355358.1
RP11-379F12.3
GATA3 antisense RNA 1
chr17_-_27621125 0.12 ENST00000579665.1
ENST00000225388.4
nuclear fragile X mental retardation protein interacting protein 2
chr14_-_24017647 0.12 ENST00000555334.1
zinc finger homeobox 2
chr2_-_239148599 0.12 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
hes family bHLH transcription factor 6
chr12_+_4714145 0.12 ENST00000545342.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chrX_+_135279179 0.12 ENST00000370676.3
four and a half LIM domains 1
chr10_+_1102303 0.12 ENST00000381329.1
WD repeat domain 37
chrX_-_70128554 0.12 ENST00000395889.2
testis expressed 11
chr17_+_7477040 0.12 ENST00000581384.1
ENST00000577929.1
eukaryotic translation initiation factor 4A1
chr2_-_183387430 0.11 ENST00000410103.1
phosphodiesterase 1A, calmodulin-dependent
chr8_+_67405755 0.11 ENST00000521495.1
chromosome 8 open reading frame 46
chrX_+_47444613 0.11 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr5_-_59481406 0.11 ENST00000546160.1
phosphodiesterase 4D, cAMP-specific
chr2_-_30144432 0.11 ENST00000389048.3
anaplastic lymphoma receptor tyrosine kinase
chr5_-_36241900 0.11 ENST00000381937.4
ENST00000514504.1
NAD kinase 2, mitochondrial
chr15_+_44084503 0.11 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
small EDRK-rich factor 2
chr6_+_29555683 0.11 ENST00000383640.2
olfactory receptor, family 2, subfamily H, member 2
chr2_-_220083076 0.11 ENST00000295750.4
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_+_41222998 0.11 ENST00000263370.2
inositol-trisphosphate 3-kinase C
chr17_-_8301132 0.11 ENST00000399398.2
ring finger protein 222
chr8_+_61822605 0.11 ENST00000526936.1
AC022182.1
chr9_-_32573130 0.11 ENST00000350021.2
ENST00000379847.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr11_+_44587141 0.11 ENST00000227155.4
ENST00000342935.3
ENST00000532544.1
CD82 molecule
chr3_-_45267760 0.11 ENST00000503771.1
transmembrane protein 158 (gene/pseudogene)
chr1_+_155657737 0.11 ENST00000471642.2
ENST00000471214.1
death associated protein 3
chr7_+_5229904 0.11 ENST00000382384.2
WD repeat domain, phosphoinositide interacting 2
chr9_+_126773880 0.11 ENST00000373615.4
LIM homeobox 2
chr17_+_49242796 0.11 ENST00000514264.2
ENST00000393185.1
NME1-NME2 readthrough
chr11_+_110001723 0.11 ENST00000528673.1
zinc finger CCCH-type containing 12C
chr13_-_88323514 0.11 ENST00000441617.1
MIR4500 host gene (non-protein coding)
chr7_-_74867509 0.11 ENST00000426327.3
GATS protein-like 2
chr12_+_53491220 0.11 ENST00000548547.1
ENST00000301464.3
insulin-like growth factor binding protein 6
chr13_+_102104952 0.11 ENST00000376180.3
integrin, beta-like 1 (with EGF-like repeat domains)
chr17_-_77925806 0.11 ENST00000574241.2
TBC1 domain family, member 16
chr17_+_19030782 0.11 ENST00000344415.4
ENST00000577213.1
GRB2-related adaptor protein-like
chr15_-_28419569 0.11 ENST00000569772.1
HECT and RLD domain containing E3 ubiquitin protein ligase 2
chr7_+_66800928 0.10 ENST00000430244.1
RP11-166O4.5
chr5_-_80689945 0.10 ENST00000307624.3
acyl-CoA thioesterase 12
chr18_-_56985776 0.10 ENST00000587244.1
complexin 4
chr6_-_30080863 0.10 ENST00000540829.1
tripartite motif containing 31
chr22_-_36236265 0.10 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RNA binding protein, fox-1 homolog (C. elegans) 2
chr9_-_131644306 0.10 ENST00000302586.3
cysteine conjugate-beta lyase, cytoplasmic
chr11_-_46638720 0.10 ENST00000326737.3
harbinger transposase derived 1
chr9_-_140351928 0.10 ENST00000339554.3
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr1_-_153363452 0.10 ENST00000368732.1
ENST00000368733.3
S100 calcium binding protein A8
chrX_-_11445856 0.10 ENST00000380736.1
Rho GTPase activating protein 6
chr1_+_155051305 0.10 ENST00000368408.3
ephrin-A3

Network of associatons between targets according to the STRING database.

First level regulatory network of OLIG2_NEUROD1_ATOH1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.4 GO:0046521 sphingoid catabolic process(GO:0046521)
0.1 0.5 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.9 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.3 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.4 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.1 0.2 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.2 GO:1904346 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.3 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.1 0.3 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.1 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.2 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.2 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.2 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0018277 protein deamination(GO:0018277)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.3 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.2 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.0 0.1 GO:1904719 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0006311 meiotic gene conversion(GO:0006311) male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:2000784 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.1 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.7 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.8 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0061032 cardiac right ventricle formation(GO:0003219) noradrenergic neuron differentiation(GO:0003357) visceral serous pericardium development(GO:0061032)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.2 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:0035284 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.3 GO:0030913 paranodal junction assembly(GO:0030913)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.1 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.1 GO:0072752 cellular response to rapamycin(GO:0072752)
0.0 0.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.2 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.1 GO:0030822 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:0015811 L-cystine transport(GO:0015811)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.0 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877) negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.0 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.0 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.1 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.0 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957) auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.0 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0018377 protein myristoylation(GO:0018377)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0060203 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
0.0 0.2 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.0 GO:1990745 EARP complex(GO:1990745)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0033867 Fas-activated serine/threonine kinase activity(GO:0033867)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.5 GO:0031013 troponin I binding(GO:0031013)
0.1 0.2 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.4 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.1 0.3 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.2 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.4 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0031768 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.1 0.2 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.2 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.2 GO:1904315 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0004645 phosphorylase activity(GO:0004645)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0047536 2-aminoadipate transaminase activity(GO:0047536)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.1 GO:0015186 L-cystine transmembrane transporter activity(GO:0015184) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.0 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.1 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0035240 dopamine binding(GO:0035240)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.4 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.2 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway