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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for NR2E3
Z-value: 1.39
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Transcription factors associated with NR2E3
Network of associatons between targets according to the STRING database.
First level regulatory network of NR2E3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.3 | 1.3 | GO:2000097 | negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097) |
| 0.2 | 1.1 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.0 | 1.1 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 0.3 | 0.9 | GO:0030070 | insulin processing(GO:0030070) |
| 0.1 | 0.9 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.1 | 0.8 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 0.1 | 0.6 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.1 | 0.6 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.1 | 0.6 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.2 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 1.1 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.0 | 0.9 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.9 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) |
| 0.1 | 0.8 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.0 | 0.7 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 0.6 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
| 0.1 | 0.6 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 0.6 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.6 | GO:0030057 | desmosome(GO:0030057) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 1.4 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 1.2 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.1 | 1.1 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 1.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 0.9 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.0 | 0.9 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.1 | 0.8 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 0.6 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.1 | 0.6 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 1.2 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.0 | 1.0 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.8 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 0.6 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.5 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.0 | 0.4 | PID LYMPH ANGIOGENESIS PATHWAY | VEGFR3 signaling in lymphatic endothelium |
| 0.0 | 0.4 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.0 | 0.3 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.2 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 1.1 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 0.8 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.8 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.0 | 0.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.8 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.7 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.6 | REACTOME POL SWITCHING | Genes involved in Polymerase switching |
| 0.0 | 0.6 | REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 0.6 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |