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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NR2E1

Z-value: 0.94

Motif logo

Transcription factors associated with NR2E1

Gene Symbol Gene ID Gene Info
ENSG00000112333.7 nuclear receptor subfamily 2 group E member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2E1hg19_v2_chr6_+_108487245_1084872620.663.4e-01Click!

Activity profile of NR2E1 motif

Sorted Z-values of NR2E1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_148939598 1.25 ENST00000455472.3
ceruloplasmin (ferroxidase)
chrY_+_15418467 1.11 ENST00000595988.1
Uncharacterized protein
chr16_-_66952779 0.94 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr16_-_66952742 0.84 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr6_+_131521120 0.81 ENST00000537868.1
A kinase (PRKA) anchor protein 7
chr22_-_41842781 0.66 ENST00000434408.1
transducer of ERBB2, 2
chr7_+_142829162 0.58 ENST00000291009.3
prolactin-induced protein
chr3_-_112356944 0.57 ENST00000461431.1
coiled-coil domain containing 80
chr19_-_49567124 0.56 ENST00000301411.3
neurotrophin 4
chr1_-_197036364 0.55 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr2_-_190445499 0.51 ENST00000261024.2
solute carrier family 40 (iron-regulated transporter), member 1
chr20_+_57875457 0.49 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
endothelin 3
chr1_+_212738676 0.46 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr2_-_55237484 0.46 ENST00000394609.2
reticulon 4
chr3_-_148939835 0.45 ENST00000264613.6
ceruloplasmin (ferroxidase)
chr12_-_90049878 0.42 ENST00000359142.3
ATPase, Ca++ transporting, plasma membrane 1
chr5_-_55777586 0.42 ENST00000506836.1
Uncharacterized protein
chr12_+_40618873 0.42 ENST00000298910.7
leucine-rich repeat kinase 2
chr12_-_51418549 0.41 ENST00000548150.1
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr12_+_86268065 0.40 ENST00000551529.1
ENST00000256010.6
neurotensin
chr15_+_48413211 0.39 ENST00000449382.2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr14_-_92302784 0.39 ENST00000340892.5
ENST00000360594.5
tandem C2 domains, nuclear
chr15_-_34502197 0.38 ENST00000557877.1
katanin p80 subunit B-like 1
chr7_+_90012986 0.38 ENST00000416322.1
claudin 12
chrX_+_47077680 0.38 ENST00000522883.1
cyclin-dependent kinase 16
chr9_-_99064429 0.38 ENST00000375263.3
hydroxysteroid (17-beta) dehydrogenase 3
chr12_-_111180644 0.37 ENST00000551676.1
ENST00000550991.1
ENST00000335007.5
ENST00000340766.5
protein phosphatase 1, catalytic subunit, gamma isozyme
chrX_+_10031499 0.37 ENST00000454666.1
WWC family member 3
chr9_-_119162885 0.37 ENST00000445861.2
PAPPA antisense RNA 1
chr9_-_75567962 0.36 ENST00000297785.3
ENST00000376939.1
aldehyde dehydrogenase 1 family, member A1
chr11_-_111794446 0.35 ENST00000527950.1
crystallin, alpha B
chr12_-_90049828 0.35 ENST00000261173.2
ENST00000348959.3
ATPase, Ca++ transporting, plasma membrane 1
chr15_-_34502278 0.35 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
katanin p80 subunit B-like 1
chr18_+_13382553 0.35 ENST00000586222.1
low density lipoprotein receptor class A domain containing 4
chr3_-_139396801 0.34 ENST00000413939.2
ENST00000339837.5
ENST00000512391.1
nicotinamide nucleotide adenylyltransferase 3
chr17_+_70036164 0.34 ENST00000602013.1
Uncharacterized protein
chr22_+_25465786 0.34 ENST00000401395.1
KIAA1671
chr7_-_130066571 0.33 ENST00000492389.1
centrosomal protein 41kDa
chr17_-_46667628 0.33 ENST00000498678.1
homeobox B3
chr4_+_52917451 0.32 ENST00000295213.4
ENST00000419395.2
spermatogenesis associated 18
chr16_+_21608525 0.32 ENST00000567404.1
methyltransferase like 9
chr2_-_45162783 0.32 ENST00000432125.2
RP11-89K21.1
chr17_-_46667594 0.32 ENST00000476342.1
ENST00000460160.1
ENST00000472863.1
homeobox B3
chr11_-_63439013 0.32 ENST00000398868.3
atlastin GTPase 3
chr15_+_23255242 0.31 ENST00000450802.3
golgin A8 family, member I
chr11_-_63439174 0.31 ENST00000332645.4
atlastin GTPase 3
chr9_-_3469181 0.31 ENST00000366116.2
Uncharacterized protein
chr15_+_36887069 0.31 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
chromosome 15 open reading frame 41
chr6_+_125540951 0.30 ENST00000524679.1
tumor protein D52-like 1
chr16_+_47495225 0.30 ENST00000299167.8
ENST00000323584.5
ENST00000563376.1
phosphorylase kinase, beta
chr12_+_56624436 0.29 ENST00000266980.4
ENST00000437277.1
solute carrier family 39 (zinc transporter), member 5
chr16_-_10652993 0.29 ENST00000536829.1
epithelial membrane protein 2
chr20_-_4229721 0.29 ENST00000379453.4
adrenoceptor alpha 1D
chr16_+_47495201 0.28 ENST00000566044.1
ENST00000455779.1
phosphorylase kinase, beta
chr3_-_139396853 0.28 ENST00000406164.1
ENST00000406824.1
nicotinamide nucleotide adenylyltransferase 3
chr16_+_47496023 0.28 ENST00000567200.1
phosphorylase kinase, beta
chr4_+_96012614 0.28 ENST00000264568.4
bone morphogenetic protein receptor, type IB
chr2_+_67624430 0.28 ENST00000272342.5
Ewing tumor-associated antigen 1
chr9_-_98189055 0.27 ENST00000433644.2
RP11-435O5.2
chrX_-_106362013 0.27 ENST00000372487.1
ENST00000372479.3
ENST00000203616.8
RNA binding motif protein 41
chr12_+_79258444 0.27 ENST00000261205.4
synaptotagmin I
chr20_-_45980621 0.27 ENST00000446894.1
zinc finger, MYND-type containing 8
chr15_+_48413169 0.26 ENST00000341459.3
ENST00000482911.2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
chr21_-_46492927 0.26 ENST00000599569.1
Uncharacterized protein
chr1_+_150229554 0.26 ENST00000369111.4
carbonic anhydrase XIV
chrX_-_128657457 0.26 ENST00000371121.3
ENST00000371123.1
ENST00000371122.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr13_-_54706954 0.26 ENST00000606706.1
ENST00000607494.1
ENST00000427299.2
ENST00000423442.2
ENST00000451744.1
long intergenic non-protein coding RNA 458
chr5_-_42811986 0.26 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
selenoprotein P, plasma, 1
chr12_-_68696652 0.26 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr2_-_111291587 0.26 ENST00000437167.1
RANBP2-like and GRIP domain containing 6
chr1_-_108231101 0.25 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr16_-_15180257 0.24 ENST00000540462.1
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr10_-_115423792 0.24 ENST00000369360.3
ENST00000360478.3
ENST00000359988.3
ENST00000369358.4
nebulin-related anchoring protein
chr6_-_10747802 0.24 ENST00000606522.1
ENST00000606652.1
RP11-421M1.8
chr14_+_24407940 0.24 ENST00000354854.1
DHRS4-AS1
chr14_+_31494841 0.24 ENST00000556232.1
ENST00000216366.4
ENST00000334725.4
ENST00000554609.1
ENST00000554345.1
adaptor-related protein complex 4, sigma 1 subunit
chr11_+_3877412 0.23 ENST00000527651.1
stromal interaction molecule 1
chr13_+_110958124 0.23 ENST00000400163.2
collagen, type IV, alpha 2
chr3_+_179322481 0.23 ENST00000259037.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr12_-_31479045 0.23 ENST00000539409.1
ENST00000395766.1
family with sequence similarity 60, member A
chr4_-_153303658 0.23 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_+_79258547 0.22 ENST00000457153.2
synaptotagmin I
chr11_-_8832182 0.22 ENST00000527510.1
ENST00000528527.1
ENST00000528523.1
ENST00000313726.6
suppression of tumorigenicity 5
chr5_+_71475449 0.22 ENST00000504492.1
microtubule-associated protein 1B
chr12_-_8088773 0.22 ENST00000544291.1
solute carrier family 2 (facilitated glucose transporter), member 3
chr3_+_69788576 0.22 ENST00000352241.4
ENST00000448226.2
microphthalmia-associated transcription factor
chr20_+_33589048 0.22 ENST00000446156.1
ENST00000453028.1
ENST00000435272.1
ENST00000433934.2
ENST00000456649.1
myosin, heavy chain 7B, cardiac muscle, beta
chr8_+_104384616 0.22 ENST00000520337.1
collagen triple helix repeat containing 1
chr14_+_39734482 0.21 ENST00000554392.1
ENST00000555716.1
ENST00000341749.3
ENST00000557038.1
CTAGE family, member 5
chr2_+_207630081 0.20 ENST00000236980.6
ENST00000418289.1
ENST00000402774.3
ENST00000403094.3
FAST kinase domains 2
chr4_-_157892055 0.20 ENST00000422544.2
platelet derived growth factor C
chr9_+_2029019 0.20 ENST00000382194.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr15_+_58702742 0.19 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr14_-_71107921 0.19 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
chr7_-_5998714 0.19 ENST00000539903.1
radial spoke head 10 homolog B (Chlamydomonas)
chr12_+_72061563 0.19 ENST00000551238.1
THAP domain containing, apoptosis associated protein 2
chr3_+_141106643 0.19 ENST00000514251.1
zinc finger and BTB domain containing 38
chr6_-_108582168 0.19 ENST00000426155.2
sorting nexin 3
chr5_-_142780280 0.19 ENST00000424646.2
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_+_240408560 0.18 ENST00000441342.1
ENST00000545751.1
formin 2
chr22_-_33968239 0.18 ENST00000452586.2
ENST00000421768.1
like-glycosyltransferase
chr2_+_27760247 0.18 ENST00000447166.1
Uncharacterized protein
chr3_+_122044084 0.18 ENST00000264474.3
ENST00000479204.1
cystatin A (stefin A)
chr7_-_72936608 0.18 ENST00000404251.1
bromodomain adjacent to zinc finger domain, 1B
chr6_+_74405501 0.18 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr17_+_29664830 0.18 ENST00000444181.2
ENST00000417592.2
neurofibromin 1
chr12_+_40618764 0.18 ENST00000343742.2
leucine-rich repeat kinase 2
chr17_+_46133307 0.18 ENST00000580037.1
nuclear factor, erythroid 2-like 1
chr20_-_45976816 0.18 ENST00000441977.1
zinc finger, MYND-type containing 8
chr7_-_151217166 0.17 ENST00000496004.1
Ras homolog enriched in brain
chr9_-_99064386 0.17 ENST00000375262.2
hydroxysteroid (17-beta) dehydrogenase 3
chr5_+_75699149 0.17 ENST00000379730.3
IQ motif containing GTPase activating protein 2
chr5_-_37371163 0.17 ENST00000513532.1
nucleoporin 155kDa
chr7_+_116166331 0.17 ENST00000393468.1
ENST00000393467.1
caveolin 1, caveolae protein, 22kDa
chr4_-_141348999 0.17 ENST00000325617.5
calmegin
chr8_-_17942432 0.16 ENST00000381733.4
ENST00000314146.10
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr10_-_13350447 0.16 ENST00000429930.1
Uncharacterized protein
chr3_+_189349162 0.16 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
tumor protein p63
chr14_+_31494672 0.16 ENST00000542754.2
ENST00000313566.6
adaptor-related protein complex 4, sigma 1 subunit
chr17_-_29624343 0.16 ENST00000247271.4
oligodendrocyte myelin glycoprotein
chrX_+_114874727 0.16 ENST00000543070.1
plastin 3
chr9_-_5339873 0.16 ENST00000223862.1
ENST00000223858.4
relaxin 1
chr16_-_3068171 0.16 ENST00000572154.1
ENST00000328796.4
claudin 6
chr1_-_244006528 0.16 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr2_-_207630033 0.16 ENST00000449792.1
malate dehydrogenase 1B, NAD (soluble)
chr7_+_106809406 0.16 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HMG-box transcription factor 1
chr2_+_181845763 0.16 ENST00000602499.1
ubiquitin-conjugating enzyme E2E 3
chr9_+_5890802 0.15 ENST00000381477.3
ENST00000381476.1
ENST00000381471.1
melan-A
chr4_+_81187753 0.15 ENST00000312465.7
ENST00000456523.3
fibroblast growth factor 5
chr4_-_40631859 0.15 ENST00000295971.7
ENST00000319592.4
RNA binding motif protein 47
chr3_+_141106458 0.15 ENST00000509883.1
zinc finger and BTB domain containing 38
chr11_-_1619524 0.15 ENST00000412090.1
keratin associated protein 5-2
chr12_-_110883346 0.15 ENST00000547365.1
actin related protein 2/3 complex, subunit 3, 21kDa
chr6_+_107077471 0.14 ENST00000369044.1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr1_-_44818599 0.14 ENST00000537474.1
ERI1 exoribonuclease family member 3
chr7_-_100026280 0.14 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
zinc finger, CW type with PWWP domain 1
chr9_-_5304432 0.14 ENST00000416837.1
ENST00000308420.3
relaxin 2
chr3_+_138340067 0.14 ENST00000479848.1
Fas apoptotic inhibitory molecule
chr3_+_69928256 0.14 ENST00000394355.2
microphthalmia-associated transcription factor
chr6_+_12290586 0.14 ENST00000379375.5
endothelin 1
chr17_+_9479944 0.13 ENST00000396219.3
ENST00000352665.5
WD repeat domain 16
chr19_+_24009879 0.13 ENST00000354585.4
ribosomal protein SA pseudogene 58
chr12_-_122018346 0.13 ENST00000377069.4
lysine (K)-specific demethylase 2B
chr12_-_28124903 0.13 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
parathyroid hormone-like hormone
chr9_+_4662282 0.13 ENST00000381883.2
phosphatidic acid phosphatase type 2 domain containing 2
chr6_-_41039567 0.13 ENST00000468811.1
O-acyl-ADP-ribose deacylase 1
chr7_-_72936531 0.13 ENST00000339594.4
bromodomain adjacent to zinc finger domain, 1B
chr7_+_148936732 0.13 ENST00000335870.2
zinc finger protein 212
chr13_+_95364963 0.12 ENST00000438290.2
SOX21 antisense RNA 1 (head to head)
chr17_-_76220740 0.12 ENST00000600484.1
Uncharacterized protein
chr1_+_25944341 0.12 ENST00000263979.3
mannosidase, alpha, class 1C, member 1
chr11_+_3876859 0.12 ENST00000300737.4
stromal interaction molecule 1
chr14_+_39735411 0.12 ENST00000603904.1
cTAGE family member 5 isoform 4
chr10_+_114709999 0.12 ENST00000355995.4
ENST00000545257.1
ENST00000543371.1
ENST00000536810.1
ENST00000355717.4
ENST00000538897.1
ENST00000534894.1
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr11_-_111781454 0.12 ENST00000533280.1
crystallin, alpha B
chr3_-_138048631 0.12 ENST00000484930.1
ENST00000475751.1
NME/NM23 family member 9
chrX_-_138914394 0.12 ENST00000327569.3
ENST00000361648.2
ENST00000370543.1
ENST00000359686.2
ATPase, class VI, type 11C
chr8_+_91013676 0.12 ENST00000519410.1
ENST00000522161.1
ENST00000517761.1
ENST00000520227.1
2,4-dienoyl CoA reductase 1, mitochondrial
chr17_+_46918925 0.12 ENST00000502761.1
calcium binding and coiled-coil domain 2
chr5_-_111091948 0.12 ENST00000447165.2
neuronal regeneration related protein
chr5_+_173763250 0.12 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
chr16_+_57653989 0.12 ENST00000567835.1
ENST00000569372.1
ENST00000563548.1
ENST00000562003.1
G protein-coupled receptor 56
chr5_-_158757895 0.12 ENST00000231228.2
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr8_+_76452097 0.12 ENST00000396423.2
hepatocyte nuclear factor 4, gamma
chr5_+_75699040 0.12 ENST00000274364.6
IQ motif containing GTPase activating protein 2
chr14_+_62164340 0.11 ENST00000557538.1
ENST00000539097.1
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr15_-_74374891 0.11 ENST00000290438.3
golgin A6 family, member A
chr3_-_179322416 0.11 ENST00000259038.2
mitochondrial ribosomal protein L47
chr7_-_107880508 0.11 ENST00000425651.2
neuronal cell adhesion molecule
chr11_+_100784231 0.11 ENST00000531183.1
Rho GTPase activating protein 42
chr2_-_208030295 0.11 ENST00000458272.1
Kruppel-like factor 7 (ubiquitous)
chr1_+_178995021 0.11 ENST00000263733.4
family with sequence similarity 20, member B
chr15_+_31196080 0.11 ENST00000561607.1
ENST00000565466.1
FANCD2/FANCI-associated nuclease 1
chr2_-_25194476 0.11 ENST00000534855.1
DnaJ (Hsp40) homolog, subfamily C, member 27
chr5_+_56471592 0.11 ENST00000511209.1
GC-rich promoter binding protein 1
chr7_+_134671234 0.11 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
ATP/GTP binding protein-like 3
chr12_+_14518598 0.11 ENST00000261168.4
ENST00000538511.1
ENST00000545723.1
ENST00000543189.1
ENST00000536444.1
activating transcription factor 7 interacting protein
chr9_-_125240235 0.10 ENST00000259357.2
olfactory receptor, family 1, subfamily J, member 1
chr14_+_67291158 0.10 ENST00000555456.1
gephyrin
chr14_-_103434869 0.10 ENST00000559043.1
CDC42 binding protein kinase beta (DMPK-like)
chr1_-_169703203 0.10 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
selectin E
chr3_-_50360165 0.10 ENST00000428028.1
hyaluronoglucosaminidase 2
chr12_-_99548645 0.09 ENST00000549025.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_95846556 0.09 ENST00000426881.2
RP11-14O19.2
chr3_-_93747425 0.09 ENST00000315099.2
syntaxin 19
chr12_+_6898674 0.09 ENST00000541982.1
ENST00000539492.1
CD4 molecule
chr17_-_56494713 0.09 ENST00000407977.2
ring finger protein 43
chr12_+_122018697 0.09 ENST00000541574.1
RP13-941N14.1
chr9_+_21409146 0.09 ENST00000380205.1
interferon, alpha 8
chr1_+_201708992 0.09 ENST00000367295.1
neuron navigator 1
chr4_+_3388057 0.09 ENST00000538395.1
regulator of G-protein signaling 12
chr12_+_64238539 0.09 ENST00000357825.3
SLIT-ROBO Rho GTPase activating protein 1
chr12_-_53343633 0.09 ENST00000546826.1
keratin 8
chr8_+_107593198 0.09 ENST00000517686.1
oxidation resistance 1
chr14_-_68157084 0.09 ENST00000557564.1
RP11-1012A1.4
chr2_-_207629997 0.08 ENST00000454776.2
malate dehydrogenase 1B, NAD (soluble)
chr4_-_40632605 0.08 ENST00000514014.1
RNA binding motif protein 47
chr1_-_68698197 0.08 ENST00000370973.2
ENST00000370971.1
wntless Wnt ligand secretion mediator
chr11_-_107436443 0.08 ENST00000429370.1
ENST00000417449.2
ENST00000428149.2
alkB, alkylation repair homolog 8 (E. coli)
chr4_+_22999152 0.08 ENST00000511453.1
RP11-412P11.1

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2E1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1902823 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.2 0.6 GO:0010160 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.2 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.6 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.1 0.6 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.7 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.6 GO:0021546 rhombomere development(GO:0021546)
0.1 0.8 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.1 0.5 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.5 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.1 0.4 GO:0015692 lead ion transport(GO:0015692)
0.1 0.7 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 0.2 GO:1903336 intralumenal vesicle formation(GO:0070676) negative regulation of vacuolar transport(GO:1903336)
0.1 0.2 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.1 0.4 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.2 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 1.6 GO:0006825 copper ion transport(GO:0006825)
0.1 0.1 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.1 0.2 GO:1903609 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.4 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.1 0.3 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 1.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.0 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0070836 caveola assembly(GO:0070836)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.4 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.7 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.8 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.3 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0071880 positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0061339 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.0 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.0 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:0060694 regulation of cholesterol transporter activity(GO:0060694) negative regulation of pancreatic stellate cell proliferation(GO:2000230)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.6 GO:0044753 amphisome(GO:0044753)
0.1 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.5 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.1 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.3 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0032798 Swi5-Sfr1 complex(GO:0032798)
0.0 0.1 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 1.7 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.6 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.7 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.3 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.9 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 1.0 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.5 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.6 GO:0019864 IgG binding(GO:0019864)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.3 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.1 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.4 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.7 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.2 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.9 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4