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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NR2C1

Z-value: 1.13

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Transcription factors associated with NR2C1

Gene Symbol Gene ID Gene Info
ENSG00000120798.12 nuclear receptor subfamily 2 group C member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR2C1hg19_v2_chr12_-_95467267_95467350-0.554.5e-01Click!

Activity profile of NR2C1 motif

Sorted Z-values of NR2C1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_124873357 1.47 ENST00000448614.1
nuclear receptor corepressor 2
chr9_-_16253112 1.12 ENST00000380683.1
chromosome 9 open reading frame 92
chr5_+_1801503 1.00 ENST00000274137.5
ENST00000469176.1
NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)
chr19_-_49371711 1.00 ENST00000355496.5
ENST00000263265.6
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr17_+_37821593 0.96 ENST00000578283.1
titin-cap
chr19_-_51289374 0.91 ENST00000563228.1
CTD-2568A17.1
chr12_+_48499883 0.84 ENST00000546755.1
ENST00000549366.1
ENST00000552792.1
phosphofructokinase, muscle
chr7_+_100770328 0.83 ENST00000223095.4
ENST00000445463.2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr6_-_160147925 0.81 ENST00000535561.1
superoxide dismutase 2, mitochondrial
chr12_-_6665200 0.79 ENST00000336604.4
ENST00000396840.2
ENST00000356896.4
intermediate filament family orphan 1
chr3_+_107318157 0.78 ENST00000406780.1
bobby sox homolog (Drosophila)
chr6_-_160148356 0.76 ENST00000401980.3
ENST00000545162.1
superoxide dismutase 2, mitochondrial
chr2_-_154335300 0.59 ENST00000325926.3
reprimo, TP53 dependent G2 arrest mediator candidate
chr19_+_10197463 0.57 ENST00000590378.1
ENST00000397881.3
chromosome 19 open reading frame 66
chr12_+_107349606 0.54 ENST00000547242.1
ENST00000551489.1
ENST00000550344.1
chromosome 12 open reading frame 23
chr1_+_212797789 0.53 ENST00000294829.3
family with sequence similarity 71, member A
chr8_+_96037255 0.49 ENST00000286687.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr19_-_38806390 0.48 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr14_-_69444957 0.47 ENST00000556571.1
ENST00000553659.1
ENST00000555616.1
actinin, alpha 1
chr9_-_35685452 0.46 ENST00000607559.1
tropomyosin 2 (beta)
chr10_+_104005272 0.46 ENST00000369983.3
golgi brefeldin A resistant guanine nucleotide exchange factor 1
chr14_+_21492331 0.45 ENST00000533984.1
ENST00000532213.2
AL161668.5
chr19_+_6464502 0.45 ENST00000308243.7
crumbs homolog 3 (Drosophila)
chr16_-_88752889 0.45 ENST00000332281.5
snail family zinc finger 3
chr2_-_202316169 0.42 ENST00000430254.1
trafficking protein, kinesin binding 2
chr22_+_47158578 0.42 ENST00000355704.3
TBC1 domain family, member 22A
chr1_+_45140400 0.41 ENST00000453711.1
chromosome 1 open reading frame 228
chr1_-_155880672 0.40 ENST00000609492.1
ENST00000368322.3
Ras-like without CAAX 1
chr2_+_74757050 0.39 ENST00000352222.3
ENST00000437202.1
HtrA serine peptidase 2
chr1_-_229569834 0.38 ENST00000366684.3
ENST00000366683.2
actin, alpha 1, skeletal muscle
chr22_-_50699701 0.38 ENST00000395780.1
mitogen-activated protein kinase 12
chr9_-_34397800 0.37 ENST00000297623.2
chromosome 9 open reading frame 24
chr12_+_109577202 0.37 ENST00000377848.3
ENST00000377854.5
acetyl-CoA carboxylase beta
chr15_+_90728145 0.37 ENST00000561085.1
ENST00000379122.3
ENST00000332496.6
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_+_160148593 0.37 ENST00000337387.4
Wilms tumor 1 associated protein
chr8_-_80680078 0.36 ENST00000337919.5
ENST00000354724.3
hes-related family bHLH transcription factor with YRPW motif 1
chr2_-_219134822 0.36 ENST00000444053.1
ENST00000248450.4
angio-associated, migratory cell protein
chr15_+_75335604 0.35 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr15_-_82555000 0.34 ENST00000557844.1
ENST00000359445.3
ENST00000268206.7
elongation factor Tu GTP binding domain containing 1
chr2_-_219134343 0.33 ENST00000447885.1
ENST00000420660.1
angio-associated, migratory cell protein
chr4_-_111544254 0.31 ENST00000306732.3
paired-like homeodomain 2
chr17_+_13972807 0.31 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
cytochrome c oxidase assembly homolog 10 (yeast)
chr19_+_11350278 0.31 ENST00000252453.8
chromosome 19 open reading frame 80
chr8_+_110656344 0.31 ENST00000499579.1
Uncharacterized protein
chr20_+_44486246 0.30 ENST00000255152.2
ENST00000454862.2
zinc finger, SWIM-type containing 3
chr17_-_15902951 0.30 ENST00000472495.1
zinc finger, SWIM-type containing 7
chr2_+_201936707 0.30 ENST00000433898.1
ENST00000454214.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr12_-_48499826 0.30 ENST00000551798.1
SUMO1/sentrin specific peptidase 1
chr2_+_201936458 0.29 ENST00000237889.4
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr4_+_26321284 0.29 ENST00000506956.1
ENST00000512671.1
ENST00000345843.3
ENST00000342295.1
recombination signal binding protein for immunoglobulin kappa J region
chr14_+_74003818 0.28 ENST00000311148.4
acyl-CoA thioesterase 1
chr6_-_31138439 0.27 ENST00000259915.8
POU class 5 homeobox 1
chr11_+_67798363 0.27 ENST00000525628.1
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr2_+_33701286 0.27 ENST00000403687.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_179125907 0.27 ENST00000247461.4
ENST00000452673.2
ENST00000502498.1
ENST00000507307.1
ENST00000513246.1
ENST00000502673.1
ENST00000506654.1
ENST00000512607.2
ENST00000510810.1
calnexin
chr3_+_37284824 0.27 ENST00000431105.1
golgin A4
chr19_+_48828788 0.27 ENST00000594198.1
ENST00000597279.1
ENST00000593437.1
epithelial membrane protein 3
chr19_+_676385 0.27 ENST00000166139.4
follistatin-like 3 (secreted glycoprotein)
chr1_-_917466 0.26 ENST00000341290.2
chromosome 1 open reading frame 170
chr11_+_67798114 0.26 ENST00000453471.2
ENST00000528492.1
ENST00000526339.1
ENST00000525419.1
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr9_-_77643189 0.26 ENST00000376837.3
chromosome 9 open reading frame 41
chr11_-_65430554 0.26 ENST00000308639.9
ENST00000406246.3
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr12_-_109797249 0.26 ENST00000538041.1
RP11-256L11.1
chr18_+_54318616 0.25 ENST00000254442.3
WD repeat domain 7
chr19_+_44100544 0.24 ENST00000391965.2
ENST00000525771.1
zinc finger protein 576
chr17_-_39203519 0.24 ENST00000542137.1
ENST00000391419.3
keratin associated protein 2-1
chr17_-_36105009 0.24 ENST00000560016.1
ENST00000427275.2
ENST00000561193.1
HNF1 homeobox B
chr19_-_38806540 0.23 ENST00000592694.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr11_+_67798090 0.23 ENST00000313468.5
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase)
chr13_+_21714913 0.23 ENST00000450573.1
ENST00000467636.1
Sin3A-associated protein, 18kDa
chr22_+_47158518 0.23 ENST00000337137.4
ENST00000380995.1
ENST00000407381.3
TBC1 domain family, member 22A
chr2_-_163099885 0.22 ENST00000443424.1
fibroblast activation protein, alpha
chr11_-_45939565 0.22 ENST00000525192.1
ENST00000378750.5
peroxisomal biogenesis factor 16
chr7_+_143080063 0.22 ENST00000446634.1
zyxin
chr22_+_30163340 0.22 ENST00000330029.6
ENST00000401406.3
ubiquinol-cytochrome c reductase, complex III subunit X
chr11_-_72414256 0.22 ENST00000427971.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr17_+_80674559 0.21 ENST00000269373.6
ENST00000535965.1
ENST00000577128.1
ENST00000573158.1
fructosamine 3 kinase related protein
chr8_-_80942467 0.21 ENST00000518271.1
ENST00000276585.4
ENST00000521605.1
mitochondrial ribosomal protein S28
chr19_+_39616410 0.21 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
p21 protein (Cdc42/Rac)-activated kinase 4
chr12_-_109219937 0.21 ENST00000546697.1
slingshot protein phosphatase 1
chr18_+_54318566 0.21 ENST00000589935.1
ENST00000357574.3
WD repeat domain 7
chr19_+_48828582 0.20 ENST00000270221.6
ENST00000596315.1
epithelial membrane protein 3
chr16_+_30710462 0.20 ENST00000262518.4
ENST00000395059.2
ENST00000344771.4
Snf2-related CREBBP activator protein
chr13_-_33760216 0.20 ENST00000255486.4
StAR-related lipid transfer (START) domain containing 13
chr3_+_101546827 0.19 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr19_+_6464243 0.19 ENST00000600229.1
ENST00000356762.3
crumbs homolog 3 (Drosophila)
chr1_+_110577229 0.18 ENST00000369795.3
ENST00000369794.2
striatin interacting protein 1
chr9_-_139839064 0.18 ENST00000325285.3
ENST00000428398.1
F-box and WD repeat domain containing 5
chr17_-_49021974 0.17 ENST00000501718.2
RP11-700H6.1
chr19_-_46142362 0.17 ENST00000586770.1
ENST00000591721.1
echinoderm microtubule associated protein like 2
chr21_-_32931290 0.16 ENST00000286827.3
T-cell lymphoma invasion and metastasis 1
chr11_-_72414430 0.16 ENST00000452383.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr19_-_38806560 0.16 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
Yip1 interacting factor homolog B (S. cerevisiae)
chr2_-_163100045 0.16 ENST00000188790.4
fibroblast activation protein, alpha
chr3_-_50605150 0.16 ENST00000357203.3
chromosome 3 open reading frame 18
chr19_+_45116921 0.16 ENST00000402988.1
immunoglobulin superfamily, member 23
chr12_+_132413739 0.16 ENST00000443358.2
pseudouridylate synthase 1
chr1_+_159750776 0.15 ENST00000368107.1
dual specificity phosphatase 23
chr20_-_57607347 0.15 ENST00000395663.1
ENST00000395659.1
ENST00000243997.3
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr1_+_26872324 0.15 ENST00000531382.1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_-_48499591 0.14 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SUMO1/sentrin specific peptidase 1
chr20_-_44485835 0.14 ENST00000457981.1
ENST00000426915.1
ENST00000217455.4
acyl-CoA thioesterase 8
chr20_+_19870167 0.13 ENST00000440354.2
Ras and Rab interactor 2
chr12_-_118810688 0.13 ENST00000542532.1
ENST00000392533.3
TAO kinase 3
chr1_-_29508321 0.13 ENST00000546138.1
serine/arginine-rich splicing factor 4
chr18_+_54318893 0.13 ENST00000593058.1
WD repeat domain 7
chr10_-_23633720 0.13 ENST00000323327.4
chromosome 10 open reading frame 67
chr16_+_2255710 0.13 ENST00000397124.1
ENST00000565250.1
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr2_+_210636697 0.13 ENST00000439458.1
ENST00000272845.6
unc-80 homolog (C. elegans)
chr12_+_132413798 0.13 ENST00000440818.2
ENST00000542167.2
ENST00000538037.1
ENST00000456665.2
pseudouridylate synthase 1
chr11_+_10471836 0.12 ENST00000444303.2
adenosine monophosphate deaminase 3
chr19_-_18548921 0.12 ENST00000545187.1
ENST00000578352.1
inositol-3-phosphate synthase 1
chr1_+_159750720 0.12 ENST00000368109.1
ENST00000368108.3
dual specificity phosphatase 23
chr9_-_139137648 0.12 ENST00000358701.5
quiescin Q6 sulfhydryl oxidase 2
chr15_-_43802769 0.12 ENST00000263801.3
tumor protein p53 binding protein 1
chr19_+_10196981 0.11 ENST00000591813.1
chromosome 19 open reading frame 66
chr3_+_183903811 0.11 ENST00000429586.2
ENST00000292808.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr17_-_80023659 0.11 ENST00000578907.1
ENST00000577907.1
ENST00000578176.1
ENST00000582529.1
dihydrouridine synthase 1-like (S. cerevisiae)
chr22_-_29784519 0.10 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
adaptor-related protein complex 1, beta 1 subunit
chr16_+_83932684 0.10 ENST00000262430.4
malonyl-CoA decarboxylase
chr15_-_43863695 0.09 ENST00000439195.1
diphosphoinositol pentakisphosphate kinase 1
chr2_-_96701722 0.08 ENST00000434632.1
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr10_+_127661942 0.08 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr19_+_4153598 0.08 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
cAMP responsive element binding protein 3-like 3
chr6_+_133561725 0.08 ENST00000452339.2
eyes absent homolog 4 (Drosophila)
chr6_+_149068464 0.08 ENST00000367463.4
uronyl-2-sulfotransferase
chr6_+_33172407 0.08 ENST00000374662.3
hydroxysteroid (17-beta) dehydrogenase 8
chrX_-_19817869 0.08 ENST00000379698.4
SH3-domain kinase binding protein 1
chr3_+_159557637 0.08 ENST00000445224.2
schwannomin interacting protein 1
chr2_+_109237717 0.07 ENST00000409441.1
LIM and senescent cell antigen-like domains 1
chr14_-_21492113 0.07 ENST00000554094.1
NDRG family member 2
chr2_+_219135115 0.07 ENST00000248451.3
ENST00000273077.4
paroxysmal nonkinesigenic dyskinesia
chr19_-_18548962 0.07 ENST00000317018.6
ENST00000581800.1
ENST00000583534.1
ENST00000457269.4
ENST00000338128.8
inositol-3-phosphate synthase 1
chr7_+_120969045 0.07 ENST00000222462.2
wingless-type MMTV integration site family, member 16
chr20_+_37590942 0.07 ENST00000373325.2
ENST00000252011.3
ENST00000373323.4
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr2_+_219433588 0.07 ENST00000295701.5
RCD1 required for cell differentiation1 homolog (S. pombe)
chr6_+_54172653 0.06 ENST00000370869.3
tubulointerstitial nephritis antigen
chr3_-_50605077 0.06 ENST00000426034.1
ENST00000441239.1
chromosome 3 open reading frame 18
chr17_+_4853442 0.06 ENST00000522301.1
enolase 3 (beta, muscle)
chr14_-_65289812 0.06 ENST00000389720.3
ENST00000389721.5
ENST00000389722.3
spectrin, beta, erythrocytic
chr10_-_103815874 0.06 ENST00000370033.4
ENST00000311122.5
chromosome 10 open reading frame 76
chr1_-_45140227 0.06 ENST00000372237.3
transmembrane protein 53
chr2_+_120124497 0.06 ENST00000355857.3
ENST00000535617.1
ENST00000535757.1
ENST00000409094.1
ENST00000311521.4
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr16_-_70729496 0.06 ENST00000567648.1
Vac14 homolog (S. cerevisiae)
chr14_+_74035763 0.06 ENST00000238651.5
acyl-CoA thioesterase 2
chr6_+_31515337 0.05 ENST00000376148.4
ENST00000376145.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr8_+_77318769 0.05 ENST00000518732.1
long intergenic non-protein coding RNA 1111
chr19_+_44100727 0.05 ENST00000528387.1
ENST00000529930.1
ENST00000336564.4
ENST00000607544.1
ENST00000526798.1
zinc finger protein 576
serine/arginine repetitive matrix 5
chr10_-_73479546 0.04 ENST00000441508.2
chromosome 10 open reading frame 105
chr19_+_16771936 0.04 ENST00000187762.2
ENST00000599479.1
transmembrane protein 38A
chr11_-_45939374 0.04 ENST00000533151.1
ENST00000241041.3
peroxisomal biogenesis factor 16
chr3_-_126236588 0.04 ENST00000383579.3
urocanate hydratase 1
chr9_+_135037334 0.03 ENST00000393229.3
ENST00000360670.3
ENST00000393228.4
ENST00000372179.3
netrin G2
chr4_-_99064387 0.03 ENST00000295268.3
sperm-tail PG-rich repeat containing 2
chr13_+_21714711 0.03 ENST00000607003.1
ENST00000492245.1
Sin3A-associated protein, 18kDa
chr4_+_159593418 0.03 ENST00000507475.1
ENST00000307738.5
electron-transferring-flavoprotein dehydrogenase
chr16_+_2255841 0.03 ENST00000301725.7
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr12_-_54070098 0.03 ENST00000394349.3
ENST00000549164.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr2_+_219433281 0.02 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RCD1 required for cell differentiation1 homolog (S. pombe)
chr2_-_74757066 0.02 ENST00000377526.3
ancient ubiquitous protein 1
chr15_-_65715401 0.02 ENST00000352385.2
immunoglobulin superfamily, DCC subclass, member 4
chr10_-_118502070 0.02 ENST00000369209.3
heat shock 70kDa protein 12A
chr19_-_10679697 0.02 ENST00000335766.2
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr22_+_41777927 0.02 ENST00000266304.4
thyrotrophic embryonic factor
chr12_+_96252706 0.02 ENST00000266735.5
ENST00000553192.1
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr4_-_151936416 0.02 ENST00000510413.1
ENST00000507224.1
LPS-responsive vesicle trafficking, beach and anchor containing
chr6_+_30594619 0.02 ENST00000318999.7
ENST00000376485.4
ENST00000376478.2
ENST00000319027.5
ENST00000376483.4
ENST00000329992.8
ENST00000330083.5
alpha tubulin acetyltransferase 1
chr11_+_94501497 0.02 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
angiomotin like 1
chr9_+_33795533 0.01 ENST00000379405.3
protease, serine, 3
chr2_+_120125245 0.01 ENST00000393103.2
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr2_-_42721110 0.01 ENST00000394973.4
ENST00000306078.1
potassium voltage-gated channel, subfamily G, member 3
chr12_-_54069856 0.00 ENST00000602871.1
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr12_-_63544718 0.00 ENST00000299178.2
arginine vasopressin receptor 1A
chr10_+_26986582 0.00 ENST00000376215.5
ENST00000376203.5
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr1_+_40713573 0.00 ENST00000372766.3
transmembrane and coiled-coil domains 2
chr15_+_65369082 0.00 ENST00000432196.2
kelch repeat and BTB (POZ) domain containing 13
chr20_+_30946106 0.00 ENST00000375687.4
ENST00000542461.1
additional sex combs like 1 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of NR2C1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.3 1.0 GO:0035995 detection of muscle stretch(GO:0035995)
0.3 1.6 GO:0003069 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.3 0.8 GO:0001300 chronological cell aging(GO:0001300)
0.1 0.8 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.4 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.1 0.2 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.5 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.1 0.3 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
0.1 0.3 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.3 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.4 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.1 0.4 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.5 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.1 0.3 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.4 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.3 GO:0060578 subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) superior vena cava morphogenesis(GO:0060578)
0.0 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:1905068 positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 2.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.0 0.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.2 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.4 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.0 0.5 GO:0032060 bleb assembly(GO:0032060)
0.0 0.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.4 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 2.4 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.4 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.3 GO:0070069 cytochrome complex(GO:0070069)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0051373 FATZ binding(GO:0051373)
0.2 1.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.3 GO:0004730 pseudouridylate synthase activity(GO:0004730)
0.1 0.4 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.8 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 1.5 GO:0005112 Notch binding(GO:0005112)
0.0 2.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.4 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.6 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 2.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.3 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 1.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle