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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NR1I3

Z-value: 0.79

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Transcription factors associated with NR1I3

Gene Symbol Gene ID Gene Info
NR1I3
ENSG00000143257.7 nuclear receptor subfamily 1 group I member 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I3hg19_v2_chr1_-_161207986_161208000-0.346.6e-01Click!

Activity profile of NR1I3 motif

Sorted Z-values of NR1I3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_53626974 0.42 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr14_+_53173890 0.40 ENST00000445930.2
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr11_+_933555 0.35 ENST00000534485.1
AP2A2
adaptor-related protein complex 2, alpha 2 subunit
chr20_+_5987890 0.34 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr12_+_100594557 0.32 ENST00000546902.1
ENST00000552376.1
ENST00000551617.1
ACTR6
ARP6 actin-related protein 6 homolog (yeast)
chr1_+_145516560 0.29 ENST00000537888.1
PEX11B
peroxisomal biogenesis factor 11 beta
chr1_+_145516252 0.29 ENST00000369306.3
PEX11B
peroxisomal biogenesis factor 11 beta
chr11_-_71781096 0.29 ENST00000535087.1
ENST00000535838.1
NUMA1
nuclear mitotic apparatus protein 1
chr9_-_35361262 0.26 ENST00000599954.1
AL160274.1
HCG17281; PRO0038; Uncharacterized protein
chr14_+_53173910 0.25 ENST00000606149.1
ENST00000555339.1
ENST00000556813.1
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr5_+_139055021 0.24 ENST00000502716.1
ENST00000503511.1
CXXC5
CXXC finger protein 5
chr11_-_104480019 0.24 ENST00000536529.1
ENST00000545630.1
ENST00000538641.1
RP11-886D15.1
RP11-886D15.1
chr19_+_9203855 0.24 ENST00000429566.3
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr17_-_62503015 0.23 ENST00000581806.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr16_+_53133070 0.22 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr8_-_143833918 0.21 ENST00000359228.3
LYPD2
LY6/PLAUR domain containing 2
chr5_-_138780159 0.20 ENST00000512473.1
ENST00000515581.1
ENST00000515277.1
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr5_+_139055055 0.19 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr19_-_58919815 0.18 ENST00000597980.1
CTD-2619J13.14
CTD-2619J13.14
chr11_-_82611448 0.18 ENST00000393399.2
ENST00000313010.3
PRCP
prolylcarboxypeptidase (angiotensinase C)
chr1_-_21625486 0.18 ENST00000481130.2
ECE1
endothelin converting enzyme 1
chr1_-_235116495 0.18 ENST00000549744.1
RP11-443B7.3
RP11-443B7.3
chr1_-_33336414 0.17 ENST00000373471.3
ENST00000609187.1
FNDC5
fibronectin type III domain containing 5
chr1_+_82165350 0.17 ENST00000359929.3
LPHN2
latrophilin 2
chr18_-_23670546 0.16 ENST00000542743.1
ENST00000545952.1
ENST00000539849.1
ENST00000415083.2
SS18
synovial sarcoma translocation, chromosome 18
chr18_-_19284724 0.15 ENST00000580981.1
ENST00000289119.2
ABHD3
abhydrolase domain containing 3
chr18_-_19283649 0.15 ENST00000584464.1
ENST00000578270.1
ABHD3
abhydrolase domain containing 3
chr12_-_118810688 0.15 ENST00000542532.1
ENST00000392533.3
TAOK3
TAO kinase 3
chr15_+_96875657 0.15 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_-_33390667 0.15 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr1_+_45274154 0.14 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTBD19
BTB (POZ) domain containing 19
chr12_+_53817633 0.14 ENST00000257863.4
ENST00000550311.1
ENST00000379791.3
AMHR2
anti-Mullerian hormone receptor, type II
chr1_-_225616515 0.14 ENST00000338179.2
ENST00000425080.1
LBR
lamin B receptor
chr18_-_23671139 0.14 ENST00000579061.1
ENST00000542420.2
SS18
synovial sarcoma translocation, chromosome 18
chr7_-_56160625 0.14 ENST00000446428.1
ENST00000432123.1
ENST00000452681.2
ENST00000537360.1
PHKG1
phosphorylase kinase, gamma 1 (muscle)
chr2_-_228028829 0.13 ENST00000396625.3
ENST00000329662.7
COL4A4
collagen, type IV, alpha 4
chr16_+_58535372 0.13 ENST00000566656.1
ENST00000566618.1
NDRG4
NDRG family member 4
chr13_-_114107839 0.12 ENST00000375418.3
ADPRHL1
ADP-ribosylhydrolase like 1
chr2_-_209118974 0.12 ENST00000415913.1
ENST00000415282.1
ENST00000446179.1
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr9_+_134001455 0.12 ENST00000531584.1
NUP214
nucleoporin 214kDa
chr5_-_39270725 0.12 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr13_+_60971080 0.12 ENST00000377894.2
TDRD3
tudor domain containing 3
chr6_-_127780510 0.12 ENST00000487331.2
ENST00000483725.3
KIAA0408
KIAA0408
chr6_+_96969672 0.11 ENST00000369278.4
UFL1
UFM1-specific ligase 1
chr1_+_154377669 0.11 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr2_-_86790472 0.11 ENST00000409727.1
CHMP3
charged multivesicular body protein 3
chr1_+_153330322 0.11 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr12_-_108991812 0.10 ENST00000392806.3
ENST00000547567.1
TMEM119
transmembrane protein 119
chr11_-_71753188 0.10 ENST00000543009.1
NUMA1
nuclear mitotic apparatus protein 1
chr16_+_67280799 0.10 ENST00000566345.2
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr14_+_21525981 0.10 ENST00000308227.2
RNASE8
ribonuclease, RNase A family, 8
chr19_-_49140609 0.10 ENST00000601104.1
DBP
D site of albumin promoter (albumin D-box) binding protein
chr12_+_57998400 0.10 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr6_+_71276596 0.10 ENST00000370474.3
C6orf57
chromosome 6 open reading frame 57
chr11_-_61124776 0.10 ENST00000542361.1
CYB561A3
cytochrome b561 family, member A3
chr17_-_53499310 0.10 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr19_-_7562334 0.08 ENST00000593942.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr17_-_62502399 0.08 ENST00000450599.2
ENST00000585060.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr10_+_71444655 0.08 ENST00000434931.2
RP11-242G20.1
Uncharacterized protein
chr22_+_39493207 0.08 ENST00000348946.4
ENST00000442487.3
ENST00000421988.2
APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr4_+_70894130 0.08 ENST00000526767.1
ENST00000530128.1
ENST00000381057.3
HTN3
histatin 3
chr1_+_32930647 0.07 ENST00000609129.1
ZBTB8B
zinc finger and BTB domain containing 8B
chr6_+_33422343 0.07 ENST00000395064.2
ZBTB9
zinc finger and BTB domain containing 9
chr9_-_80646374 0.07 ENST00000286548.4
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr14_-_50506589 0.07 ENST00000553914.2
RP11-58E21.3
RP11-58E21.3
chr2_-_86790593 0.07 ENST00000263856.4
ENST00000409225.2
CHMP3
charged multivesicular body protein 3
chr22_+_39493268 0.06 ENST00000401756.1
APOBEC3H
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
chr6_-_56258892 0.06 ENST00000370819.1
COL21A1
collagen, type XXI, alpha 1
chrX_-_153583257 0.06 ENST00000438732.1
FLNA
filamin A, alpha
chr17_-_53499218 0.06 ENST00000571578.1
MMD
monocyte to macrophage differentiation-associated
chr5_-_176937351 0.05 ENST00000377112.4
ENST00000501403.2
ENST00000312943.6
DOK3
docking protein 3
chr17_-_62502639 0.05 ENST00000225792.5
ENST00000581697.1
ENST00000584279.1
ENST00000577922.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr5_+_52856456 0.05 ENST00000296684.5
ENST00000506765.1
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr5_-_176936817 0.05 ENST00000502885.1
ENST00000506493.1
DOK3
docking protein 3
chr4_-_82136114 0.05 ENST00000395578.1
ENST00000418486.2
PRKG2
protein kinase, cGMP-dependent, type II
chrX_+_118602363 0.04 ENST00000317881.8
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chrX_+_110924346 0.04 ENST00000371979.3
ENST00000251943.4
ENST00000486353.1
ENST00000394780.3
ENST00000495283.1
ALG13
ALG13, UDP-N-acetylglucosaminyltransferase subunit
chr14_-_22005062 0.04 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr5_+_156712372 0.04 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr9_-_114937676 0.04 ENST00000374270.3
SUSD1
sushi domain containing 1
chr6_-_43496605 0.04 ENST00000455285.2
XPO5
exportin 5
chr19_-_6604094 0.04 ENST00000597430.2
CD70
CD70 molecule
chr9_+_124048864 0.04 ENST00000545652.1
GSN
gelsolin
chr19_+_12203069 0.04 ENST00000430298.2
ENST00000339302.4
ZNF788
ZNF788
zinc finger family member 788
Zinc finger protein 788
chr1_+_26036093 0.03 ENST00000374329.1
MAN1C1
mannosidase, alpha, class 1C, member 1
chr2_-_128642434 0.03 ENST00000393001.1
AMMECR1L
AMMECR1-like
chr14_-_22005018 0.03 ENST00000546363.1
SALL2
spalt-like transcription factor 2
chr11_+_63137251 0.03 ENST00000310969.4
ENST00000279178.3
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr11_-_61124711 0.03 ENST00000536915.1
CYB561A3
cytochrome b561 family, member A3
chr11_-_57089774 0.03 ENST00000527207.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chrX_+_69674943 0.03 ENST00000542398.1
DLG3
discs, large homolog 3 (Drosophila)
chr19_-_46285646 0.03 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr13_-_20806440 0.02 ENST00000400066.3
ENST00000400065.3
ENST00000356192.6
GJB6
gap junction protein, beta 6, 30kDa
chr1_-_1690014 0.02 ENST00000400922.2
ENST00000342348.5
NADK
NAD kinase
chr9_-_75567962 0.02 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr4_+_146402346 0.02 ENST00000514778.1
ENST00000507594.1
SMAD1
SMAD family member 1
chr1_-_9086404 0.02 ENST00000400906.1
SLC2A7
solute carrier family 2 (facilitated glucose transporter), member 7
chr19_+_58920102 0.01 ENST00000599238.1
ENST00000322834.7
ZNF584
zinc finger protein 584
chr1_-_23886285 0.01 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr10_+_47658234 0.01 ENST00000447511.2
ENST00000537271.1
ANTXRL
anthrax toxin receptor-like
chr7_-_99381798 0.01 ENST00000415003.1
ENST00000354593.2
CYP3A4
cytochrome P450, family 3, subfamily A, polypeptide 4
chr9_-_91793675 0.01 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr3_-_58419537 0.01 ENST00000474765.1
ENST00000485460.1
ENST00000302746.6
ENST00000383714.4
PDHB
pyruvate dehydrogenase (lipoamide) beta
chr12_-_53729525 0.01 ENST00000303846.3
SP7
Sp7 transcription factor
chr16_-_16317321 0.01 ENST00000205557.7
ENST00000575728.1
ABCC6
ATP-binding cassette, sub-family C (CFTR/MRP), member 6
chr15_+_96876340 0.00 ENST00000453270.2
NR2F2
nuclear receptor subfamily 2, group F, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.4 GO:0032887 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.3 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.7 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.2 GO:0002254 regulation of thyroid hormone mediated signaling pathway(GO:0002155) kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.0 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.0 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.3 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.4 GO:0055028 cortical microtubule(GO:0055028)
0.0 0.4 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.1 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.0 0.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.0 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043337 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.3 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.0 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.0 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling