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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NR1I2

Z-value: 1.05

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Transcription factors associated with NR1I2

Gene Symbol Gene ID Gene Info
ENSG00000144852.12 nuclear receptor subfamily 1 group I member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NR1I2hg19_v2_chr3_+_119499331_1194993310.752.5e-01Click!

Activity profile of NR1I2 motif

Sorted Z-values of NR1I2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_46035187 1.20 ENST00000300557.2
proline rich 15-like
chr1_+_229440129 1.12 ENST00000366688.3
S-phase response (cyclin related)
chr16_+_28874345 0.96 ENST00000566209.1
SH2B adaptor protein 1
chr17_-_7082861 0.82 ENST00000269299.3
asialoglycoprotein receptor 1
chr15_+_96875657 0.75 ENST00000559679.1
ENST00000394171.2
nuclear receptor subfamily 2, group F, member 2
chr16_-_67427389 0.65 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr19_-_36304201 0.61 ENST00000301175.3
proline dehydrogenase (oxidase) 2
chr1_-_12679171 0.61 ENST00000606790.1
RP11-474O21.5
chr19_-_51289436 0.57 ENST00000562076.1
CTD-2568A17.1
chr1_-_197036364 0.57 ENST00000367412.1
coagulation factor XIII, B polypeptide
chr18_+_3466248 0.56 ENST00000581029.1
ENST00000581442.1
ENST00000579007.1
RP11-838N2.4
chr5_+_139055055 0.54 ENST00000511457.1
CXXC finger protein 5
chr5_-_55777586 0.52 ENST00000506836.1
Uncharacterized protein
chr2_-_86790472 0.51 ENST00000409727.1
charged multivesicular body protein 3
chr15_+_96876340 0.49 ENST00000453270.2
nuclear receptor subfamily 2, group F, member 2
chr7_-_95225768 0.46 ENST00000005178.5
pyruvate dehydrogenase kinase, isozyme 4
chr1_+_207277632 0.46 ENST00000421786.1
complement component 4 binding protein, alpha
chr6_+_84743436 0.45 ENST00000257776.4
melanocortin 2 receptor accessory protein 2
chr1_-_169555779 0.45 ENST00000367797.3
ENST00000367796.3
coagulation factor V (proaccelerin, labile factor)
chr4_-_159094194 0.44 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr4_+_95972822 0.44 ENST00000509540.1
ENST00000440890.2
bone morphogenetic protein receptor, type IB
chr5_+_134074231 0.44 ENST00000514518.1
calcium modulating ligand
chr4_-_110723335 0.44 ENST00000394634.2
complement factor I
chr1_+_45274154 0.43 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTB (POZ) domain containing 19
chr11_+_86502085 0.43 ENST00000527521.1
protease, serine, 23
chr13_-_46679144 0.43 ENST00000181383.4
carboxypeptidase B2 (plasma)
chr1_+_61869748 0.42 ENST00000357977.5
nuclear factor I/A
chr13_-_30424821 0.42 ENST00000380680.4
ubiquitin-like 3
chr15_+_36887069 0.41 ENST00000566807.1
ENST00000567389.1
ENST00000562877.1
chromosome 15 open reading frame 41
chr11_-_27384737 0.41 ENST00000317945.6
coiled-coil domain containing 34
chr4_+_71859156 0.41 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
deoxycytidine kinase
chr12_-_27167233 0.40 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
transmembrane 7 superfamily member 3
chr2_-_178417742 0.39 ENST00000408939.3
tetratricopeptide repeat domain 30B
chr15_-_64673630 0.39 ENST00000558008.1
ENST00000559519.1
ENST00000380258.2
KIAA0101
chr13_-_46679185 0.39 ENST00000439329.3
carboxypeptidase B2 (plasma)
chr3_+_153839149 0.38 ENST00000465093.1
ENST00000465817.1
Rho guanine nucleotide exchange factor (GEF) 26
chr9_-_14313893 0.38 ENST00000380921.3
ENST00000380959.3
nuclear factor I/B
chr14_-_58893832 0.37 ENST00000556007.2
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_-_245026388 0.37 ENST00000440865.1
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr2_+_223916862 0.37 ENST00000604125.1
potassium voltage-gated channel, Isk-related family, member 4
chr8_-_101733794 0.37 ENST00000523555.1
poly(A) binding protein, cytoplasmic 1
chr2_-_86790593 0.37 ENST00000263856.4
ENST00000409225.2
charged multivesicular body protein 3
chr16_+_83986827 0.37 ENST00000393306.1
ENST00000565123.1
oxidative stress induced growth inhibitor 1
chrX_-_30327495 0.37 ENST00000453287.1
nuclear receptor subfamily 0, group B, member 1
chr5_+_139055021 0.37 ENST00000502716.1
ENST00000503511.1
CXXC finger protein 5
chr5_+_78908233 0.36 ENST00000453514.1
ENST00000423041.2
ENST00000504233.1
ENST00000428308.2
PAP associated domain containing 4
chr1_-_54879140 0.36 ENST00000525990.1
single stranded DNA binding protein 3
chr3_+_118892411 0.36 ENST00000479520.1
ENST00000494855.1
uroplakin 1B
chr3_+_37284668 0.36 ENST00000361924.2
ENST00000444882.1
ENST00000356847.4
ENST00000450863.2
ENST00000429018.1
golgin A4
chr14_-_90085458 0.36 ENST00000345097.4
ENST00000555855.1
ENST00000555353.1
forkhead box N3
chr5_+_78908388 0.36 ENST00000296783.3
PAP associated domain containing 4
chr5_-_154230130 0.35 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
fatty acid hydroxylase domain containing 2
chr17_-_27503770 0.35 ENST00000533112.1
myosin XVIIIA
chr20_-_46415297 0.35 ENST00000467815.1
ENST00000359930.4
sulfatase 2
chr1_-_55089191 0.34 ENST00000302250.2
ENST00000371304.2
family with sequence similarity 151, member A
chr16_+_28875126 0.34 ENST00000359285.5
ENST00000538342.1
SH2B adaptor protein 1
chr7_-_86848933 0.34 ENST00000423734.1
transmembrane protein 243, mitochondrial
chr3_+_118892362 0.33 ENST00000497685.1
ENST00000264234.3
uroplakin 1B
chr17_-_74528128 0.33 ENST00000590175.1
cytoglobin
chr1_+_201979743 0.33 ENST00000446188.1
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr11_-_111794446 0.33 ENST00000527950.1
crystallin, alpha B
chr17_-_46682321 0.33 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr20_+_57875457 0.33 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
endothelin 3
chr11_+_117073850 0.33 ENST00000529622.1
transgelin
chr8_+_62200509 0.32 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
clavesin 1
chr6_-_85474219 0.32 ENST00000369663.5
T-box 18
chr3_+_112930306 0.32 ENST00000495514.1
BOC cell adhesion associated, oncogene regulated
chr1_-_26185844 0.32 ENST00000538789.1
ENST00000374298.3
aurora kinase A and ninein interacting protein
chr4_-_110723194 0.32 ENST00000394635.3
complement factor I
chr15_-_64673665 0.32 ENST00000300035.4
KIAA0101
chr5_-_73937244 0.31 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr17_-_7082668 0.31 ENST00000573083.1
ENST00000574388.1
asialoglycoprotein receptor 1
chr4_+_20702059 0.31 ENST00000444671.2
ENST00000510700.1
ENST00000506745.1
ENST00000514663.1
ENST00000509469.1
ENST00000515339.1
ENST00000513861.1
ENST00000502374.1
ENST00000538990.1
ENST00000511160.1
ENST00000504630.1
ENST00000513590.1
ENST00000514292.1
ENST00000502938.1
ENST00000509625.1
ENST00000505160.1
ENST00000507634.1
ENST00000513459.1
ENST00000511089.1
PARK2 co-regulated-like
chr11_+_66624527 0.30 ENST00000393952.3
leucine rich repeat and fibronectin type III domain containing 4
chr2_+_18059906 0.30 ENST00000304101.4
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr3_-_114343039 0.29 ENST00000481632.1
zinc finger and BTB domain containing 20
chr4_-_110723134 0.29 ENST00000510800.1
ENST00000512148.1
complement factor I
chr3_-_113464906 0.29 ENST00000477813.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr14_-_102552659 0.28 ENST00000441629.2
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr12_-_8088773 0.28 ENST00000544291.1
solute carrier family 2 (facilitated glucose transporter), member 3
chr1_+_207277590 0.28 ENST00000367070.3
complement component 4 binding protein, alpha
chr12_-_86230315 0.28 ENST00000361228.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr7_+_135611542 0.28 ENST00000416501.1
AC015987.2
chr10_-_120938303 0.28 ENST00000356951.3
ENST00000298510.2
peroxiredoxin 3
chr15_+_39873268 0.28 ENST00000397591.2
ENST00000260356.5
thrombospondin 1
chr4_+_106067943 0.28 ENST00000380013.4
ENST00000394764.1
ENST00000413648.2
tet methylcytosine dioxygenase 2
chr20_-_7921090 0.28 ENST00000378789.3
hydroxyacid oxidase (glycolate oxidase) 1
chr5_-_87564620 0.27 ENST00000506536.1
ENST00000512429.1
ENST00000514135.1
ENST00000296595.6
ENST00000509387.1
transmembrane protein 161B
chr5_+_92919043 0.27 ENST00000327111.3
nuclear receptor subfamily 2, group F, member 1
chr5_+_134074191 0.27 ENST00000297156.2
calcium modulating ligand
chr17_+_53344945 0.27 ENST00000575345.1
hepatic leukemia factor
chr8_-_131028869 0.27 ENST00000518283.1
ENST00000519110.1
family with sequence similarity 49, member B
chr1_+_149858461 0.27 ENST00000331380.2
histone cluster 2, H2ac
chr1_+_196912902 0.27 ENST00000476712.2
ENST00000367415.5
complement factor H-related 2
chr4_+_71600063 0.27 ENST00000513597.1
RUN and FYVE domain containing 3
chr2_+_69240302 0.26 ENST00000303714.4
anthrax toxin receptor 1
chr19_-_38878632 0.26 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
gametogenetin
chr16_+_47495201 0.26 ENST00000566044.1
ENST00000455779.1
phosphorylase kinase, beta
chr16_+_47495225 0.26 ENST00000299167.8
ENST00000323584.5
ENST00000563376.1
phosphorylase kinase, beta
chr16_-_57520378 0.26 ENST00000340099.4
docking protein 4
chr5_+_56205081 0.25 ENST00000285947.2
ENST00000541720.1
SET domain containing 9
chr6_-_8102714 0.25 ENST00000502429.1
ENST00000429723.2
ENST00000507463.1
ENST00000379715.5
eukaryotic translation elongation factor 1 epsilon 1
chr5_+_78532003 0.25 ENST00000396137.4
junction mediating and regulatory protein, p53 cofactor
chr5_+_145317356 0.25 ENST00000511217.1
SH3 domain containing ring finger 2
chr12_-_68696652 0.25 ENST00000539972.1
Mdm1 nuclear protein homolog (mouse)
chr7_-_105332084 0.25 ENST00000472195.1
ataxin 7-like 1
chr6_+_10585979 0.25 ENST00000265012.4
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr8_-_53626974 0.25 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1-inducible coiled-coil 1
chr13_-_95364389 0.24 ENST00000376945.2
SRY (sex determining region Y)-box 21
chr4_+_20702030 0.24 ENST00000510051.1
ENST00000503585.1
ENST00000360916.5
ENST00000295290.8
ENST00000514485.1
PARK2 co-regulated-like
chr12_-_12715266 0.24 ENST00000228862.2
dual specificity phosphatase 16
chr3_-_45957088 0.24 ENST00000539217.1
leucine zipper transcription factor-like 1
chr7_-_38948774 0.24 ENST00000395969.2
ENST00000414632.1
ENST00000310301.4
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr3_+_113465866 0.24 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr4_+_124317940 0.24 ENST00000505319.1
ENST00000339241.1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr1_-_173793246 0.24 ENST00000345664.6
ENST00000367710.3
centromere protein L
chr7_+_37960163 0.23 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
ependymin related 1
chr10_+_103348031 0.23 ENST00000370151.4
ENST00000370147.1
ENST00000370148.2
deleted in primary ciliary dyskinesia homolog (mouse)
chr1_+_196788887 0.23 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chrX_+_38420623 0.23 ENST00000378482.2
tetraspanin 7
chr2_-_70475701 0.23 ENST00000282574.4
TIA1 cytotoxic granule-associated RNA binding protein
chr19_+_1248547 0.23 ENST00000586757.1
ENST00000300952.2
midnolin
chr3_+_179322573 0.23 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr14_-_58893876 0.23 ENST00000555097.1
ENST00000555404.1
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr16_+_58498194 0.23 ENST00000561779.1
ENST00000565430.1
ENST00000567063.1
ENST00000566041.1
NDRG family member 4
chr13_+_115000556 0.23 ENST00000252458.6
cell division cycle 16
chr12_+_54447637 0.22 ENST00000609810.1
ENST00000430889.2
homeobox C4
Homeobox protein Hox-C4
chr2_+_111490161 0.22 ENST00000340561.4
acyl-CoA oxidase-like
chr5_+_145583156 0.22 ENST00000265271.5
RNA binding motif protein 27
chr1_-_173793458 0.22 ENST00000356198.2
centromere protein L
chr7_-_27169801 0.22 ENST00000511914.1
homeobox A4
chr6_+_107077471 0.21 ENST00000369044.1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr7_-_72936608 0.21 ENST00000404251.1
bromodomain adjacent to zinc finger domain, 1B
chr20_+_57875758 0.21 ENST00000395654.3
endothelin 3
chr12_-_94673956 0.21 ENST00000551941.1
Uncharacterized protein
chr12_-_120315074 0.20 ENST00000261833.7
ENST00000392521.2
citron (rho-interacting, serine/threonine kinase 21)
chr12_-_6715808 0.20 ENST00000545584.1
chromodomain helicase DNA binding protein 4
chr15_+_59903975 0.20 ENST00000560585.1
ENST00000396065.1
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_+_120207787 0.20 ENST00000397843.2
ENST00000356641.3
Rho guanine nucleotide exchange factor (GEF) 12
chr1_+_43291220 0.20 ENST00000372514.3
erythroblast membrane-associated protein (Scianna blood group)
chr16_-_79804394 0.20 ENST00000567993.1
RP11-345M22.2
chr11_+_118478313 0.20 ENST00000356063.5
pleckstrin homology-like domain, family B, member 1
chr1_+_218519577 0.20 ENST00000366930.4
ENST00000366929.4
transforming growth factor, beta 2
chr3_+_179322481 0.20 ENST00000259037.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr9_-_140115775 0.19 ENST00000391553.1
ENST00000392827.1
ring finger protein 208
chr9_+_33795533 0.19 ENST00000379405.3
protease, serine, 3
chr3_+_56591184 0.19 ENST00000422222.1
ENST00000394672.3
ENST00000326595.7
coiled-coil domain containing 66
chr2_-_70475730 0.19 ENST00000445587.1
ENST00000433529.2
ENST00000415783.2
TIA1 cytotoxic granule-associated RNA binding protein
chr1_+_24646263 0.19 ENST00000524724.1
grainyhead-like 3 (Drosophila)
chr11_-_102323740 0.19 ENST00000398136.2
transmembrane protein 123
chr5_-_1801408 0.18 ENST00000505818.1
mitochondrial ribosomal protein L36
chr22_-_43567750 0.18 ENST00000494035.1
tubulin tyrosine ligase-like family, member 12
chr3_+_133293278 0.18 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
CDV3 homolog (mouse)
chr3_+_133524459 0.18 ENST00000484684.1
signal recognition particle receptor, B subunit
chr7_-_32931623 0.18 ENST00000452926.1
kelch repeat and BTB (POZ) domain containing 2
chr11_-_64013663 0.18 ENST00000392210.2
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr7_-_91875358 0.18 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1, ankyrin repeat containing
chr17_-_33905521 0.18 ENST00000225873.4
peroxisomal biogenesis factor 12
chr6_+_142623063 0.18 ENST00000296932.8
ENST00000367609.3
G protein-coupled receptor 126
chr16_-_28937027 0.18 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr17_+_48611853 0.18 ENST00000507709.1
ENST00000515126.1
ENST00000507467.1
epsin 3
chr10_-_33625154 0.17 ENST00000265371.4
neuropilin 1
chr3_+_156544057 0.17 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
leucine, glutamate and lysine rich 1
chr10_-_121296045 0.17 ENST00000392865.1
regulator of G-protein signaling 10
chr1_-_205744574 0.17 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7, member RAS oncogene family-like 1
chr11_+_10772847 0.17 ENST00000524523.1
CTR9, Paf1/RNA polymerase II complex component
chr1_+_201979645 0.17 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr13_+_115000339 0.17 ENST00000360383.3
ENST00000375312.3
cell division cycle 16
chr7_-_37026108 0.17 ENST00000396045.3
engulfment and cell motility 1
chr8_-_124286735 0.17 ENST00000395571.3
zinc fingers and homeoboxes 1
chr6_+_142622991 0.17 ENST00000230173.6
ENST00000367608.2
G protein-coupled receptor 126
chr9_+_17135016 0.17 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
centlein, centrosomal protein
chr11_-_108369101 0.17 ENST00000323468.5
KDEL (Lys-Asp-Glu-Leu) containing 2
chr1_-_151965048 0.17 ENST00000368809.1
S100 calcium binding protein A10
chr7_-_72936531 0.17 ENST00000339594.4
bromodomain adjacent to zinc finger domain, 1B
chr2_+_190306159 0.16 ENST00000314761.4
WD repeat domain 75
chr11_-_118122996 0.16 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
myelin protein zero-like 3
chr22_+_46546494 0.16 ENST00000396000.2
ENST00000262735.5
ENST00000420804.1
peroxisome proliferator-activated receptor alpha
chr2_-_219433014 0.16 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
ubiquitin specific peptidase 37
chr8_-_124286495 0.16 ENST00000297857.2
zinc fingers and homeoboxes 1
chr5_+_145316120 0.16 ENST00000359120.4
SH3 domain containing ring finger 2
chr11_+_120107344 0.16 ENST00000260264.4
POU class 2 homeobox 3
chr8_+_26150628 0.16 ENST00000523925.1
ENST00000315985.7
protein phosphatase 2, regulatory subunit B, alpha
chr8_-_131028782 0.16 ENST00000519020.1
family with sequence similarity 49, member B
chr17_-_7531121 0.16 ENST00000573566.1
ENST00000269298.5
spermidine/spermine N1-acetyltransferase family member 2
chr15_+_59730348 0.15 ENST00000288228.5
ENST00000559628.1
ENST00000557914.1
ENST00000560474.1
family with sequence similarity 81, member A
chr20_+_62492566 0.15 ENST00000369916.3
abhydrolase domain containing 16B
chr1_+_173793641 0.15 ENST00000361951.4
aspartyl-tRNA synthetase 2, mitochondrial
chr12_-_120884175 0.15 ENST00000546954.1
TP53 regulated inhibitor of apoptosis 1
chr17_-_56296580 0.15 ENST00000313863.6
ENST00000546108.1
ENST00000337050.7
ENST00000393119.2
Meckel syndrome, type 1
chr14_+_100532771 0.15 ENST00000557153.1
Enah/Vasp-like
chr3_-_193096600 0.15 ENST00000446087.1
ENST00000342358.4
ATPase type 13A5
chr10_-_103347883 0.15 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
polymerase (DNA directed), lambda
chr8_+_99956759 0.15 ENST00000522510.1
ENST00000457907.2
odd-skipped related transciption factor 2
chr17_+_33448593 0.15 ENST00000158009.5
fibronectin type III domain containing 8
chr3_+_140660634 0.14 ENST00000446041.2
ENST00000507429.1
ENST00000324194.6
solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
chr1_-_12908578 0.14 ENST00000317869.6
heterogeneous nuclear ribonucleoprotein C-like 1
chr6_-_33864684 0.14 ENST00000506222.2
ENST00000533304.1
long intergenic non-protein coding RNA 1016
chr1_+_228870824 0.14 ENST00000366691.3
ras homolog family member U
chr4_-_7436671 0.14 ENST00000319098.4
prosaposin-like 1 (gene/pseudogene)

Network of associatons between targets according to the STRING database.

First level regulatory network of NR1I2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.9 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.2 0.8 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1 0.7 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 0.4 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.4 GO:0097065 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.4 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.3 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.3 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 1.1 GO:1903027 regulation of opsonization(GO:1903027)
0.1 0.3 GO:0002605 negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 0.6 GO:0010133 proline catabolic process(GO:0006562) proline catabolic process to glutamate(GO:0010133)
0.1 0.7 GO:0071484 cellular response to light intensity(GO:0071484)
0.1 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.4 GO:0032571 response to vitamin K(GO:0032571)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.2 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.4 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.1 0.2 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.2 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.3 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.4 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.2 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.3 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:2000276 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276)
0.0 0.0 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.3 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.5 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.2 GO:0061009 common bile duct development(GO:0061009)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) dorsal root ganglion development(GO:1990791)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0014876 response to injury involved in regulation of muscle adaptation(GO:0014876)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711) negative regulation of apoptotic cell clearance(GO:2000426)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.0 0.2 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:0060018 astrocyte fate commitment(GO:0060018)
0.0 0.4 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0072553 terminal button organization(GO:0072553)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0021678 third ventricle development(GO:0021678)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.4 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.3 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.4 GO:0072189 ureter development(GO:0072189)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.0 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.1 GO:2001205 TNFSF11-mediated signaling pathway(GO:0071847) negative regulation of osteoclast development(GO:2001205)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 1.0 GO:0045840 positive regulation of mitotic nuclear division(GO:0045840)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 1.1 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.2 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
0.0 0.5 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.5 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.2 GO:0046548 retinal rod cell development(GO:0046548)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0031379 RNA-directed RNA polymerase complex(GO:0031379)
0.1 0.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.5 GO:0097165 nuclear stress granule(GO:0097165)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.6 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.6 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0031906 late endosome lumen(GO:0031906)
0.0 0.3 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.2 0.5 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) type 1 melanocortin receptor binding(GO:0070996)
0.1 0.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 1.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.3 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.1 0.4 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.3 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.1 0.2 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.4 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.3 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.5 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.2 GO:1990175 EH domain binding(GO:1990175)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0016402 pristanoyl-CoA oxidase activity(GO:0016402)
0.0 0.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.3 GO:0055103 ligase regulator activity(GO:0055103)
0.0 0.0 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.0 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.0 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.4 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling