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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NKX2-8

Z-value: 0.68

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Transcription factors associated with NKX2-8

Gene Symbol Gene ID Gene Info
NKX2-8
ENSG00000136327.6 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NKX2-8hg19_v2_chr14_-_37051798_37051831-0.643.6e-01Click!

Activity profile of NKX2-8 motif

Sorted Z-values of NKX2-8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_76251912 0.74 ENST00000370826.3
RABGGTB
Rab geranylgeranyltransferase, beta subunit
chr2_-_36779411 0.60 ENST00000406220.1
AC007401.2
Uncharacterized protein
chr13_+_108921977 0.52 ENST00000430559.1
ENST00000375887.4
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr8_-_144679264 0.51 ENST00000531953.1
ENST00000526133.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr16_-_66952779 0.51 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
CDH16
cadherin 16, KSP-cadherin
chr16_-_66952742 0.48 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
CDH16
cadherin 16, KSP-cadherin
chr16_+_88872176 0.46 ENST00000569140.1
CDT1
chromatin licensing and DNA replication factor 1
chr6_-_18249971 0.45 ENST00000507591.1
DEK
DEK oncogene
chr6_+_41010293 0.44 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
TSPO2
translocator protein 2
chr1_+_228337553 0.40 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr6_+_34433844 0.38 ENST00000244458.2
ENST00000374043.2
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr3_-_187455680 0.33 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr4_-_164253738 0.33 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
NPY1R
neuropeptide Y receptor Y1
chr4_+_141264597 0.33 ENST00000338517.4
ENST00000394203.3
ENST00000506322.1
SCOC
short coiled-coil protein
chr2_-_55277692 0.33 ENST00000394611.2
RTN4
reticulon 4
chr7_-_99716914 0.32 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr6_+_143772060 0.32 ENST00000367591.4
PEX3
peroxisomal biogenesis factor 3
chr6_+_43968306 0.32 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223
chromosome 6 open reading frame 223
chr6_+_125524785 0.31 ENST00000392482.2
TPD52L1
tumor protein D52-like 1
chr17_+_42015654 0.31 ENST00000565120.1
RP11-527L4.2
Uncharacterized protein
chr7_-_156803329 0.30 ENST00000252971.6
MNX1
motor neuron and pancreas homeobox 1
chr18_+_13382553 0.30 ENST00000586222.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr22_-_21213676 0.30 ENST00000449120.1
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr16_-_3350614 0.29 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr6_-_132272504 0.29 ENST00000367976.3
CTGF
connective tissue growth factor
chr4_-_819901 0.29 ENST00000304062.6
CPLX1
complexin 1
chr1_+_154401791 0.28 ENST00000476006.1
IL6R
interleukin 6 receptor
chr10_+_115674530 0.28 ENST00000451472.1
AL162407.1
CDNA FLJ20147 fis, clone COL07954; HCG1781466; Uncharacterized protein
chr5_+_92919043 0.28 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr15_+_40453204 0.27 ENST00000287598.6
ENST00000412359.3
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B
chr5_+_35852797 0.27 ENST00000508941.1
IL7R
interleukin 7 receptor
chr12_-_102591604 0.27 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chrX_-_64196351 0.27 ENST00000374839.3
ZC4H2
zinc finger, C4H2 domain containing
chr16_+_58426296 0.26 ENST00000426538.2
ENST00000328514.7
ENST00000318129.5
GINS3
GINS complex subunit 3 (Psf3 homolog)
chr14_+_58765103 0.25 ENST00000355431.3
ENST00000348476.3
ENST00000395168.3
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr2_-_136288740 0.25 ENST00000264159.6
ENST00000536680.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr1_+_109289279 0.25 ENST00000370008.3
STXBP3
syntaxin binding protein 3
chr5_+_176692466 0.24 ENST00000508029.1
ENST00000503056.1
NSD1
nuclear receptor binding SET domain protein 1
chr8_+_104310661 0.23 ENST00000522566.1
FZD6
frizzled family receptor 6
chr8_-_125551278 0.23 ENST00000519232.1
ENST00000523888.1
ENST00000522810.1
ENST00000519548.1
ENST00000517678.1
ENST00000605953.1
ENST00000276692.6
TATDN1
TatD DNase domain containing 1
chr17_+_76210267 0.22 ENST00000301633.4
ENST00000350051.3
ENST00000374948.2
ENST00000590449.1
BIRC5
baculoviral IAP repeat containing 5
chr3_+_187930719 0.22 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr11_-_77348821 0.21 ENST00000528364.1
ENST00000532069.1
ENST00000525428.1
CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr10_-_118032697 0.21 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr14_-_58894223 0.21 ENST00000555593.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr1_+_55464600 0.20 ENST00000371265.4
BSND
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
chr5_-_78808617 0.20 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
HOMER1
homer homolog 1 (Drosophila)
chr19_+_44037546 0.20 ENST00000601282.1
ZNF575
zinc finger protein 575
chr7_-_99277610 0.20 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
chr1_+_120839412 0.20 ENST00000355228.4
FAM72B
family with sequence similarity 72, member B
chr12_-_371994 0.20 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13
solute carrier family 6 (neurotransmitter transporter), member 13
chr14_-_92413353 0.19 ENST00000556154.1
FBLN5
fibulin 5
chrM_+_8366 0.19 ENST00000361851.1
MT-ATP8
mitochondrially encoded ATP synthase 8
chr18_-_44497308 0.19 ENST00000585916.1
ENST00000324794.7
ENST00000545673.1
PIAS2
protein inhibitor of activated STAT, 2
chr4_-_110723134 0.19 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr11_-_77348796 0.19 ENST00000263309.3
ENST00000525064.1
CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr2_-_55277654 0.19 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4
reticulon 4
chr16_+_28875268 0.18 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr9_+_21409146 0.18 ENST00000380205.1
IFNA8
interferon, alpha 8
chr14_-_58894332 0.18 ENST00000395159.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr12_+_51442101 0.18 ENST00000550929.1
ENST00000262055.4
ENST00000550442.1
ENST00000549340.1
ENST00000548209.1
ENST00000548251.1
ENST00000550814.1
ENST00000547660.1
ENST00000380123.2
ENST00000548401.1
ENST00000418425.2
ENST00000547008.1
ENST00000552739.1
LETMD1
LETM1 domain containing 1
chr14_-_58893876 0.17 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr7_-_5998714 0.17 ENST00000539903.1
RSPH10B
radial spoke head 10 homolog B (Chlamydomonas)
chrX_-_64196376 0.17 ENST00000447788.2
ZC4H2
zinc finger, C4H2 domain containing
chr10_-_101673782 0.16 ENST00000422692.1
DNMBP
dynamin binding protein
chr7_-_86974767 0.16 ENST00000610086.1
TP53TG1
TP53 target 1 (non-protein coding)
chr19_-_3600549 0.15 ENST00000589966.1
TBXA2R
thromboxane A2 receptor
chr15_-_56757329 0.15 ENST00000260453.3
MNS1
meiosis-specific nuclear structural 1
chr3_-_122134882 0.15 ENST00000330689.4
WDR5B
WD repeat domain 5B
chr12_+_66218212 0.15 ENST00000393578.3
ENST00000425208.2
ENST00000536545.1
ENST00000354636.3
HMGA2
high mobility group AT-hook 2
chr17_+_34901353 0.15 ENST00000593016.1
GGNBP2
gametogenetin binding protein 2
chr14_+_37667230 0.15 ENST00000556451.1
ENST00000556753.1
ENST00000396294.2
MIPOL1
mirror-image polydactyly 1
chr5_+_34929677 0.15 ENST00000342382.4
ENST00000382021.2
ENST00000303525.7
DNAJC21
DnaJ (Hsp40) homolog, subfamily C, member 21
chr16_+_226658 0.15 ENST00000320868.5
ENST00000397797.1
HBA1
hemoglobin, alpha 1
chr20_-_17539456 0.14 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr16_+_89696692 0.14 ENST00000261615.4
DPEP1
dipeptidase 1 (renal)
chrX_-_64196307 0.14 ENST00000545618.1
ZC4H2
zinc finger, C4H2 domain containing
chr13_+_88325498 0.14 ENST00000400028.3
SLITRK5
SLIT and NTRK-like family, member 5
chr17_-_46178527 0.13 ENST00000393408.3
CBX1
chromobox homolog 1
chr16_+_28875126 0.13 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr22_+_31518938 0.13 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
INPP5J
inositol polyphosphate-5-phosphatase J
chr1_+_42922173 0.13 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
PPCS
phosphopantothenoylcysteine synthetase
chr11_-_10828892 0.13 ENST00000525681.1
EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr2_-_55277436 0.12 ENST00000354474.6
RTN4
reticulon 4
chr14_+_21569245 0.12 ENST00000556585.2
TMEM253
transmembrane protein 253
chr19_+_2249308 0.12 ENST00000592877.1
ENST00000221496.4
AMH
anti-Mullerian hormone
chr5_-_176056974 0.12 ENST00000510387.1
ENST00000506696.1
SNCB
synuclein, beta
chr13_-_46425865 0.12 ENST00000400405.2
SIAH3
siah E3 ubiquitin protein ligase family member 3
chr2_-_3504587 0.12 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr6_+_84222220 0.11 ENST00000369700.3
PRSS35
protease, serine, 35
chr3_-_8811288 0.11 ENST00000316793.3
ENST00000431493.1
OXTR
oxytocin receptor
chr17_-_33390667 0.11 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr5_+_149737202 0.11 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1
Treacher Collins-Franceschetti syndrome 1
chr4_-_70080449 0.11 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr14_-_24732368 0.11 ENST00000544573.1
TGM1
transglutaminase 1
chr1_+_173793777 0.11 ENST00000239457.5
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr7_+_112063192 0.11 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr16_+_67034456 0.10 ENST00000540579.1
CES4A
carboxylesterase 4A
chr10_-_118032979 0.10 ENST00000355422.6
GFRA1
GDNF family receptor alpha 1
chr12_+_49658855 0.10 ENST00000549183.1
TUBA1C
tubulin, alpha 1c
chr12_+_16109519 0.10 ENST00000526530.1
DERA
deoxyribose-phosphate aldolase (putative)
chrX_+_118533269 0.10 ENST00000336249.7
SLC25A43
solute carrier family 25, member 43
chr10_-_14596140 0.10 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr3_-_114343039 0.10 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_110371720 0.10 ENST00000356688.4
SEPT10
septin 10
chr5_-_95158644 0.10 ENST00000237858.6
GLRX
glutaredoxin (thioltransferase)
chrX_+_123094672 0.09 ENST00000354548.5
ENST00000458700.1
STAG2
stromal antigen 2
chr12_+_66218903 0.09 ENST00000393577.3
HMGA2
high mobility group AT-hook 2
chrX_-_72095622 0.09 ENST00000290273.5
DMRTC1
DMRT-like family C1
chr19_-_17622269 0.09 ENST00000595116.1
CTD-3131K8.2
CTD-3131K8.2
chr2_-_152118352 0.09 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr5_+_80529104 0.09 ENST00000254035.4
ENST00000511719.1
ENST00000437669.1
ENST00000424301.2
ENST00000505060.1
CKMT2
creatine kinase, mitochondrial 2 (sarcomeric)
chr15_-_77363441 0.08 ENST00000346495.2
ENST00000424443.3
ENST00000561277.1
TSPAN3
tetraspanin 3
chr6_+_158957431 0.08 ENST00000367090.3
TMEM181
transmembrane protein 181
chr4_-_170947565 0.08 ENST00000506764.1
MFAP3L
microfibrillar-associated protein 3-like
chr14_-_24732403 0.08 ENST00000206765.6
TGM1
transglutaminase 1
chr13_+_46039037 0.08 ENST00000349995.5
COG3
component of oligomeric golgi complex 3
chr16_+_29674540 0.08 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
SPN
QPRT
sialophorin
quinolinate phosphoribosyltransferase
chr7_+_75028199 0.08 ENST00000437796.1
TRIM73
tripartite motif containing 73
chr2_+_11752379 0.08 ENST00000396123.1
GREB1
growth regulation by estrogen in breast cancer 1
chr3_-_58613323 0.08 ENST00000474531.1
ENST00000465970.1
FAM107A
family with sequence similarity 107, member A
chr14_+_76618242 0.08 ENST00000557542.1
ENST00000557263.1
ENST00000557207.1
ENST00000312858.5
ENST00000261530.7
GPATCH2L
G patch domain containing 2-like
chrX_+_72064690 0.07 ENST00000438696.1
DMRTC1B
DMRT-like family C1B
chr6_+_84222194 0.07 ENST00000536636.1
PRSS35
protease, serine, 35
chr12_+_121837905 0.07 ENST00000392465.3
ENST00000554606.1
ENST00000392464.2
ENST00000555076.1
RNF34
ring finger protein 34, E3 ubiquitin protein ligase
chr22_-_32341336 0.07 ENST00000248984.3
C22orf24
chromosome 22 open reading frame 24
chr1_+_179050512 0.07 ENST00000367627.3
TOR3A
torsin family 3, member A
chr4_-_119274121 0.06 ENST00000296498.3
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr12_-_10320190 0.06 ENST00000543993.1
ENST00000339968.6
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr15_-_77363375 0.06 ENST00000559494.1
TSPAN3
tetraspanin 3
chr3_+_239652 0.06 ENST00000435603.1
CHL1
cell adhesion molecule L1-like
chr17_-_46703826 0.06 ENST00000550387.1
ENST00000311177.5
HOXB9
homeobox B9
chr8_-_141810634 0.06 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr6_-_32731299 0.06 ENST00000435145.2
ENST00000437316.2
HLA-DQB2
major histocompatibility complex, class II, DQ beta 2
chr11_+_59705928 0.06 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr3_-_87039662 0.06 ENST00000494229.1
VGLL3
vestigial like 3 (Drosophila)
chr1_-_220101944 0.05 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chr3_-_53290016 0.05 ENST00000423525.2
ENST00000423516.1
ENST00000296289.6
ENST00000462138.1
TKT
transketolase
chr17_+_73642486 0.05 ENST00000579469.1
SMIM6
small integral membrane protein 6
chr7_+_73507409 0.05 ENST00000538333.3
LIMK1
LIM domain kinase 1
chr11_+_64808675 0.05 ENST00000529996.1
SAC3D1
SAC3 domain containing 1
chrX_-_48858667 0.05 ENST00000376423.4
ENST00000376441.1
GRIPAP1
GRIP1 associated protein 1
chr21_-_35899113 0.05 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
RCAN1
regulator of calcineurin 1
chr19_-_44259053 0.05 ENST00000601170.1
SMG9
SMG9 nonsense mediated mRNA decay factor
chr19_+_32836499 0.05 ENST00000311921.4
ENST00000544431.1
ENST00000355898.5
ZNF507
zinc finger protein 507
chr8_-_145018905 0.05 ENST00000398774.2
PLEC
plectin
chr8_+_107593198 0.05 ENST00000517686.1
OXR1
oxidation resistance 1
chr2_-_178129853 0.05 ENST00000397062.3
NFE2L2
nuclear factor, erythroid 2-like 2
chr22_+_29834572 0.05 ENST00000354373.2
RFPL1
ret finger protein-like 1
chr1_+_43291220 0.05 ENST00000372514.3
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr14_+_58765305 0.05 ENST00000445108.1
ARID4A
AT rich interactive domain 4A (RBP1-like)
chr17_+_62503147 0.05 ENST00000553412.1
CEP95
centrosomal protein 95kDa
chrX_-_48776292 0.05 ENST00000376509.4
PIM2
pim-2 oncogene
chr7_+_135242652 0.05 ENST00000285968.6
ENST00000440390.2
NUP205
nucleoporin 205kDa
chr5_-_179107975 0.04 ENST00000376974.4
CBY3
chibby homolog 3 (Drosophila)
chr18_+_44497455 0.04 ENST00000592005.1
KATNAL2
katanin p60 subunit A-like 2
chr11_+_35211429 0.04 ENST00000525688.1
ENST00000278385.6
ENST00000533222.1
CD44
CD44 molecule (Indian blood group)
chr6_-_137113604 0.04 ENST00000359015.4
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr4_-_100485143 0.04 ENST00000394877.3
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr9_-_99637820 0.04 ENST00000289032.8
ENST00000535338.1
ZNF782
zinc finger protein 782
chr7_+_30811004 0.04 ENST00000265299.6
FAM188B
family with sequence similarity 188, member B
chr2_-_55277512 0.04 ENST00000402434.2
RTN4
reticulon 4
chr22_+_20877924 0.04 ENST00000445189.1
MED15
mediator complex subunit 15
chr3_-_116163830 0.04 ENST00000333617.4
LSAMP
limbic system-associated membrane protein
chr17_+_73642315 0.04 ENST00000556126.2
SMIM6
small integral membrane protein 6
chr7_-_95025661 0.04 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3
paraoxonase 1
paraoxonase 3
chr3_+_10183447 0.04 ENST00000345392.2
VHL
von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
chr15_-_77363513 0.04 ENST00000267970.4
TSPAN3
tetraspanin 3
chr6_+_100054606 0.04 ENST00000369215.4
PRDM13
PR domain containing 13
chr11_+_18720316 0.03 ENST00000280734.2
TMEM86A
transmembrane protein 86A
chrX_+_77154935 0.03 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr9_-_128412696 0.03 ENST00000420643.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr19_-_51893782 0.03 ENST00000570516.1
CTD-2616J11.4
chromosome 19 open reading frame 84
chr19_-_51893827 0.03 ENST00000574814.1
CTD-2616J11.4
chromosome 19 open reading frame 84
chr10_+_123951957 0.03 ENST00000514539.1
TACC2
transforming, acidic coiled-coil containing protein 2
chr8_-_29120604 0.03 ENST00000521515.1
KIF13B
kinesin family member 13B
chr15_+_45422178 0.03 ENST00000389037.3
ENST00000558322.1
DUOX1
dual oxidase 1
chr22_+_32754139 0.03 ENST00000382088.3
RFPL3
ret finger protein-like 3
chr12_-_75603482 0.03 ENST00000341669.3
ENST00000298972.1
ENST00000350228.2
KCNC2
potassium voltage-gated channel, Shaw-related subfamily, member 2
chr2_-_133429091 0.03 ENST00000345008.6
LYPD1
LY6/PLAUR domain containing 1
chr10_+_24755416 0.03 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217
KIAA1217
chr22_+_32753854 0.03 ENST00000249007.4
RFPL3
ret finger protein-like 3
chrX_+_115567767 0.03 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr4_-_100485183 0.03 ENST00000394876.2
TRMT10A
tRNA methyltransferase 10 homolog A (S. cerevisiae)
chr12_-_49504449 0.03 ENST00000547675.1
LMBR1L
limb development membrane protein 1-like
chr5_+_43602750 0.03 ENST00000505678.2
ENST00000512422.1
ENST00000264663.5
NNT
nicotinamide nucleotide transhydrogenase
chr3_-_196242233 0.03 ENST00000397537.2
SMCO1
single-pass membrane protein with coiled-coil domains 1
chr17_+_39994032 0.03 ENST00000293303.4
ENST00000438813.1
KLHL10
kelch-like family member 10
chr14_+_37667118 0.03 ENST00000556615.1
ENST00000327441.7
ENST00000536774.1
MIPOL1
mirror-image polydactyly 1
chr4_-_153601136 0.03 ENST00000504064.1
ENST00000304385.3
TMEM154
transmembrane protein 154
chr17_-_28661065 0.02 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr20_-_43936937 0.02 ENST00000342716.4
ENST00000353917.5
ENST00000360607.6
ENST00000372751.4
MATN4
matrilin 4
chr13_+_108922228 0.02 ENST00000542136.1
TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr4_+_76481258 0.02 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr17_-_62503015 0.02 ENST00000581806.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr7_-_137686791 0.02 ENST00000452463.1
ENST00000330387.6
ENST00000456390.1
CREB3L2
cAMP responsive element binding protein 3-like 2
chr9_+_109685630 0.02 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr11_+_71791849 0.02 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr12_+_66218598 0.02 ENST00000541363.1
HMGA2
high mobility group AT-hook 2
chr3_-_178103144 0.02 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX2-8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.1 0.4 GO:0034059 response to anoxia(GO:0034059)
0.1 0.5 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.3 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1 0.7 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0002384 hepatic immune response(GO:0002384)
0.1 0.3 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.3 GO:0003131 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0043605 antibiotic metabolic process(GO:0016999) cellular amide catabolic process(GO:0043605)
0.0 0.1 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.3 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.2 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0002884 negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of hypersensitivity(GO:0002884)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.6 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.3 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.2 GO:2001256 chemical homeostasis within a tissue(GO:0048875) regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0005997 xylulose metabolic process(GO:0005997) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.0 0.0 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.4 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.6 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.3 GO:0019034 viral replication complex(GO:0019034)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.4 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.0 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.1 GO:0001940 male pronucleus(GO:0001940)
0.0 0.4 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.3 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.3 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.2 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.4 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.3 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.3 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:1903136 cuprous ion binding(GO:1903136)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling