Project
A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for NKX2-4
Z-value: 1.52
Motif logo
Transcription factors associated with NKX2-4
Network of associatons between targets according to the STRING database.
First level regulatory network of NKX2-4
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0034116 | positive regulation of heterotypic cell-cell adhesion(GO:0034116) |
| 0.0 | 1.1 | GO:0043101 | purine-containing compound salvage(GO:0043101) |
| 0.3 | 1.0 | GO:0035696 | monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437) |
| 0.1 | 0.8 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.2 | 0.7 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.1 | 0.7 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 0.7 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 0.0 | 0.7 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.1 | 0.6 | GO:0050915 | sensory perception of sour taste(GO:0050915) |
| 0.1 | 0.6 | GO:0030263 | apoptotic chromosome condensation(GO:0030263) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 1.1 | GO:1902560 | GMP reductase complex(GO:1902560) |
| 0.0 | 1.1 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.9 | GO:0000791 | euchromatin(GO:0000791) |
| 0.0 | 0.8 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.0 | 0.7 | GO:0030478 | actin cap(GO:0030478) |
| 0.2 | 0.6 | GO:0009330 | DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330) |
| 0.1 | 0.6 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554) |
| 0.0 | 0.6 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.6 | GO:0030057 | desmosome(GO:0030057) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.1 | GO:0003920 | GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657) |
| 0.0 | 1.0 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.0 | 0.8 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 0.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 0.7 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 0.7 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.0 | 0.7 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 0.6 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.1 | 0.6 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.0 | 0.6 | GO:0004984 | olfactory receptor activity(GO:0004984) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 0.4 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 0.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.4 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.1 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 0.0 | 0.7 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.7 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 0.6 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.0 | 0.5 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.0 | 0.4 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.4 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |