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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NKX1-2_RAX

Z-value: 1.07

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Transcription factors associated with NKX1-2_RAX

Gene Symbol Gene ID Gene Info
NKX1-2
ENSG00000229544.6 NK1 homeobox 2
RAX
ENSG00000134438.9 retina and anterior neural fold homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RAXhg19_v2_chr18_-_56940611_569406600.964.3e-02Click!
NKX1-2hg19_v2_chr10_-_126138622_1261387530.406.0e-01Click!

Activity profile of NKX1-2_RAX motif

Sorted Z-values of NKX1-2_RAX motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_57233087 2.13 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11
proline rich 11
chr17_-_57232525 1.55 ENST00000583380.1
ENST00000580541.1
ENST00000578105.1
ENST00000437036.2
SKA2
spindle and kinetochore associated complex subunit 2
chr4_-_89442940 1.53 ENST00000527353.1
PIGY
phosphatidylinositol glycan anchor biosynthesis, class Y
chr17_-_57232596 1.34 ENST00000581068.1
ENST00000330137.7
SKA2
spindle and kinetochore associated complex subunit 2
chr17_+_57232690 1.32 ENST00000262293.4
PRR11
proline rich 11
chr8_-_101571964 0.91 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46
ankyrin repeat domain 46
chr10_+_99205959 0.88 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16
zinc finger, DHHC-type containing 16
chr3_+_158519654 0.85 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1
major facilitator superfamily domain containing 1
chr10_+_99205894 0.78 ENST00000370854.3
ENST00000393760.1
ENST00000414567.1
ENST00000370846.4
ZDHHC16
zinc finger, DHHC-type containing 16
chr4_+_66536248 0.78 ENST00000514260.1
ENST00000507117.1
RP11-807H7.1
RP11-807H7.1
chr2_+_13677795 0.75 ENST00000434509.1
AC092635.1
AC092635.1
chrX_+_77166172 0.66 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr12_-_74686314 0.64 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr8_-_101571933 0.63 ENST00000520311.1
ANKRD46
ankyrin repeat domain 46
chr3_-_120400960 0.62 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr4_-_25865159 0.60 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr9_-_3469181 0.58 ENST00000366116.2
AL365202.1
Uncharacterized protein
chr6_+_26440700 0.54 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chrX_+_43515467 0.53 ENST00000338702.3
ENST00000542639.1
MAOA
monoamine oxidase A
chr14_-_53258314 0.53 ENST00000216410.3
ENST00000557604.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr7_+_138145076 0.53 ENST00000343526.4
TRIM24
tripartite motif containing 24
chr17_-_45266542 0.52 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27
cell division cycle 27
chr1_+_28261492 0.50 ENST00000373894.3
SMPDL3B
sphingomyelin phosphodiesterase, acid-like 3B
chr1_+_201979645 0.49 ENST00000367284.5
ENST00000367283.3
ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr15_+_96904487 0.49 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr2_+_27008865 0.46 ENST00000335756.4
ENST00000233505.8
CENPA
centromere protein A
chr8_-_102803163 0.44 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr17_-_4938712 0.43 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr17_-_27418537 0.41 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr16_+_53133070 0.37 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr9_-_5339873 0.35 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr2_-_239197238 0.35 ENST00000254657.3
PER2
period circadian clock 2
chr8_+_107738240 0.33 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr2_-_239197201 0.33 ENST00000254658.3
PER2
period circadian clock 2
chr9_+_135937365 0.31 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr13_+_78315295 0.31 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr12_-_112279694 0.31 ENST00000443596.1
ENST00000442119.1
MAPKAPK5-AS1
MAPKAPK5 antisense RNA 1
chr1_+_162336686 0.30 ENST00000420220.1
C1orf226
chromosome 1 open reading frame 226
chr6_+_130339710 0.29 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr19_+_8740061 0.28 ENST00000593792.1
CTD-2586B10.1
CTD-2586B10.1
chr10_-_92681033 0.28 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr13_+_36050881 0.28 ENST00000537702.1
NBEA
neurobeachin
chr11_+_71900703 0.28 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr15_+_93443419 0.27 ENST00000557381.1
ENST00000420239.2
CHD2
chromodomain helicase DNA binding protein 2
chr16_+_29832634 0.27 ENST00000565164.1
ENST00000570234.1
MVP
major vault protein
chr2_+_187371440 0.26 ENST00000445547.1
ZC3H15
zinc finger CCCH-type containing 15
chr7_+_99717230 0.26 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chr6_+_30687978 0.26 ENST00000327892.8
ENST00000435534.1
TUBB
tubulin, beta class I
chr7_-_99716914 0.25 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr1_-_159832438 0.25 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr4_+_77356248 0.25 ENST00000296043.6
SHROOM3
shroom family member 3
chr2_+_191221240 0.25 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr12_+_32832203 0.24 ENST00000553257.1
ENST00000549701.1
ENST00000358214.5
ENST00000266481.6
ENST00000551476.1
ENST00000550154.1
ENST00000547312.1
ENST00000414834.2
ENST00000381000.4
ENST00000548750.1
DNM1L
dynamin 1-like
chr14_-_88200641 0.24 ENST00000556168.1
RP11-1152H15.1
RP11-1152H15.1
chr11_+_71900572 0.22 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr17_-_39341594 0.22 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr3_-_105587879 0.22 ENST00000264122.4
ENST00000403724.1
ENST00000405772.1
CBLB
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr4_-_141348789 0.21 ENST00000414773.1
CLGN
calmegin
chr16_-_28608364 0.21 ENST00000533150.1
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_-_17766198 0.21 ENST00000375436.4
RCC2
regulator of chromosome condensation 2
chr17_+_59489112 0.21 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr6_-_111927449 0.21 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2
TRAF3 interacting protein 2
chr6_-_111927062 0.20 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr14_+_20187174 0.20 ENST00000557414.1
OR4N2
olfactory receptor, family 4, subfamily N, member 2
chr5_-_159546396 0.20 ENST00000523662.1
ENST00000456329.3
ENST00000307063.7
PWWP2A
PWWP domain containing 2A
chr6_+_52442083 0.20 ENST00000606714.1
TRAM2-AS1
TRAM2 antisense RNA 1 (head to head)
chr11_-_13011081 0.20 ENST00000532541.1
ENST00000526388.1
ENST00000534477.1
ENST00000531402.1
ENST00000527945.1
ENST00000504230.2
LINC00958
long intergenic non-protein coding RNA 958
chr6_-_82957433 0.20 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr3_+_51851612 0.19 ENST00000456080.1
IQCF3
IQ motif containing F3
chr14_+_55494323 0.19 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr6_+_26365443 0.19 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
BTN3A2
butyrophilin, subfamily 3, member A2
chr9_+_125133315 0.18 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr9_+_124329336 0.17 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr7_-_86849883 0.17 ENST00000433078.1
TMEM243
transmembrane protein 243, mitochondrial
chr20_+_43990576 0.17 ENST00000372727.1
ENST00000414310.1
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr17_-_38821373 0.15 ENST00000394052.3
KRT222
keratin 222
chr3_+_186353756 0.15 ENST00000431018.1
ENST00000450521.1
ENST00000539949.1
FETUB
fetuin B
chr10_+_35894338 0.14 ENST00000321660.1
GJD4
gap junction protein, delta 4, 40.1kDa
chr4_-_103749105 0.14 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr3_+_28390637 0.14 ENST00000420223.1
ENST00000383768.2
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr7_+_21582638 0.14 ENST00000409508.3
ENST00000328843.6
DNAH11
dynein, axonemal, heavy chain 11
chr16_-_28608424 0.14 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr14_+_55493920 0.13 ENST00000395472.2
ENST00000555846.1
SOCS4
suppressor of cytokine signaling 4
chr12_+_16500599 0.13 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
MGST1
microsomal glutathione S-transferase 1
chr20_-_50722183 0.13 ENST00000371523.4
ZFP64
ZFP64 zinc finger protein
chr8_+_107738343 0.13 ENST00000521592.1
OXR1
oxidation resistance 1
chr17_-_33390667 0.13 ENST00000378516.2
ENST00000268850.7
ENST00000394597.2
RFFL
ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
chr16_-_28937027 0.12 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr19_+_37742773 0.11 ENST00000438770.2
ENST00000591116.1
ENST00000592712.1
AC012309.5
AC012309.5
chr4_-_103749313 0.11 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr5_-_94890648 0.11 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
TTC37
tetratricopeptide repeat domain 37
chr19_-_36822551 0.10 ENST00000591372.1
LINC00665
long intergenic non-protein coding RNA 665
chr5_-_102898465 0.10 ENST00000507423.1
ENST00000230792.2
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr3_+_195447738 0.10 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr17_-_40337470 0.09 ENST00000293330.1
HCRT
hypocretin (orexin) neuropeptide precursor
chr4_+_80584903 0.09 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr2_-_74618907 0.09 ENST00000421392.1
ENST00000437375.1
DCTN1
dynactin 1
chr1_+_62439037 0.09 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr4_-_74486109 0.08 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr7_-_37488547 0.08 ENST00000453399.1
ELMO1
engulfment and cell motility 1
chr14_+_32798547 0.07 ENST00000557354.1
ENST00000557102.1
ENST00000557272.1
AKAP6
A kinase (PRKA) anchor protein 6
chr16_+_3333443 0.07 ENST00000572748.1
ENST00000573578.1
ENST00000574253.1
ZNF263
zinc finger protein 263
chr5_+_66300446 0.07 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr19_+_36239576 0.07 ENST00000587751.1
LIN37
lin-37 homolog (C. elegans)
chr12_+_16500571 0.07 ENST00000543076.1
ENST00000396210.3
MGST1
microsomal glutathione S-transferase 1
chr2_-_190446738 0.07 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr11_+_118398178 0.07 ENST00000302783.4
ENST00000539546.1
TTC36
tetratricopeptide repeat domain 36
chr6_+_160542870 0.07 ENST00000324965.4
ENST00000457470.2
SLC22A1
solute carrier family 22 (organic cation transporter), member 1
chrX_+_114827818 0.07 ENST00000420625.2
PLS3
plastin 3
chr7_-_86849836 0.06 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chrX_+_77154935 0.06 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr8_-_30670384 0.05 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr12_-_12837423 0.05 ENST00000540510.1
GPR19
G protein-coupled receptor 19
chr12_+_7013897 0.05 ENST00000007969.8
ENST00000323702.5
LRRC23
leucine rich repeat containing 23
chr22_-_32651326 0.05 ENST00000266086.4
SLC5A4
solute carrier family 5 (glucose activated ion channel), member 4
chr1_+_153746683 0.04 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr2_+_24714729 0.04 ENST00000406961.1
ENST00000405141.1
NCOA1
nuclear receptor coactivator 1
chr14_+_67831576 0.04 ENST00000555876.1
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr21_-_35796241 0.04 ENST00000450895.1
AP000322.53
AP000322.53
chr10_+_124913930 0.04 ENST00000368858.5
BUB3
BUB3 mitotic checkpoint protein
chr17_-_19364269 0.04 ENST00000421796.2
ENST00000585389.1
ENST00000609249.1
AC004448.5
AC004448.5
chr10_+_124913793 0.04 ENST00000368865.4
ENST00000538238.1
ENST00000368859.2
BUB3
BUB3 mitotic checkpoint protein
chr1_+_186265399 0.04 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr17_+_39346139 0.03 ENST00000398470.1
ENST00000318329.5
KRTAP9-1
keratin associated protein 9-1
chr8_-_29605625 0.03 ENST00000506121.3
LINC00589
long intergenic non-protein coding RNA 589
chr10_+_124914285 0.03 ENST00000407911.2
BUB3
BUB3 mitotic checkpoint protein
chr11_+_29181503 0.03 ENST00000530960.1
RP11-466I1.1
RP11-466I1.1
chr9_+_109685630 0.03 ENST00000451160.2
RP11-508N12.4
Uncharacterized protein
chr12_+_93130311 0.03 ENST00000344636.3
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr12_+_90674665 0.02 ENST00000549313.1
RP11-753N8.1
RP11-753N8.1
chr4_+_110736659 0.02 ENST00000394631.3
ENST00000226796.6
GAR1
GAR1 ribonucleoprotein
chr17_+_1666108 0.02 ENST00000570731.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr8_+_9413410 0.02 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
TNKS
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr3_-_180397256 0.01 ENST00000442201.2
CCDC39
coiled-coil domain containing 39
chr2_+_217524323 0.01 ENST00000456764.1
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr1_-_159915386 0.01 ENST00000361509.3
ENST00000368094.1
IGSF9
immunoglobulin superfamily, member 9
chr4_-_66536196 0.01 ENST00000511294.1
EPHA5
EPH receptor A5
chr7_-_87342564 0.01 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr2_+_112939365 0.01 ENST00000272559.4
FBLN7
fibulin 7
chr10_+_6779326 0.01 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr2_-_198540719 0.01 ENST00000295049.4
RFTN2
raftlin family member 2
chr11_+_112047087 0.01 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2
beta-carotene oxygenase 2
chr1_-_151804314 0.01 ENST00000318247.6
RORC
RAR-related orphan receptor C
chr14_+_74034310 0.00 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr4_-_103749205 0.00 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr1_+_100818009 0.00 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A

Network of associatons between targets according to the STRING database.

First level regulatory network of NKX1-2_RAX

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.2 0.7 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.7 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.3 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.5 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.2 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.5 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 1.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.5 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.5 GO:0060056 mammary gland involution(GO:0060056)
0.0 1.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.0 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.4 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 2.7 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0014901 regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0 0.1 GO:0070839 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395) divalent metal ion export(GO:0070839)
0.0 0.8 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.4 GO:0007249 I-kappaB kinase/NF-kappaB signaling(GO:0007249)
0.0 0.4 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.7 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.2 2.9 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 0.5 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 0.1 GO:0002947 tumor necrosis factor receptor superfamily complex(GO:0002947)
0.0 0.1 GO:1990298 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.0 GO:0043614 multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) astrocyte end-foot(GO:0097450)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 0.7 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532) copper-dependent protein binding(GO:0032767)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.5 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.5 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.4 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 1.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.3 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.1 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) norepinephrine transmembrane transporter activity(GO:0005333) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 3.7 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases