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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NFKB1

Z-value: 0.88

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Transcription factors associated with NFKB1

Gene Symbol Gene ID Gene Info
NFKB1
ENSG00000109320.7 nuclear factor kappa B subunit 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFKB1hg19_v2_chr4_+_103423055_1034231120.811.9e-01Click!

Activity profile of NFKB1 motif

Sorted Z-values of NFKB1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39759154 1.11 ENST00000331982.5
IFNL2
interferon, lambda 2
chr6_+_29691198 1.06 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr6_+_29691056 1.01 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr10_+_104154229 0.89 ENST00000428099.1
ENST00000369966.3
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr2_-_191885686 0.89 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr5_-_150467221 0.81 ENST00000522226.1
TNIP1
TNFAIP3 interacting protein 1
chr19_+_45504688 0.76 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr14_-_24616426 0.75 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr6_+_32821924 0.69 ENST00000374859.2
ENST00000453265.2
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9
chr17_+_40440481 0.68 ENST00000590726.2
ENST00000452307.2
ENST00000444283.1
ENST00000588868.1
STAT5A
signal transducer and activator of transcription 5A
chr22_-_37640277 0.64 ENST00000401529.3
ENST00000249071.6
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_-_37640456 0.64 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr7_+_69064566 0.62 ENST00000403018.2
AUTS2
autism susceptibility candidate 2
chr6_-_32821599 0.61 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr12_+_56732658 0.60 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr5_-_150460914 0.58 ENST00000389378.2
TNIP1
TNFAIP3 interacting protein 1
chr5_-_150460539 0.53 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr16_-_66959429 0.53 ENST00000420652.1
ENST00000299759.6
RRAD
Ras-related associated with diabetes
chr2_-_163175133 0.53 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr5_-_150466692 0.52 ENST00000315050.7
ENST00000523338.1
ENST00000522100.1
TNIP1
TNFAIP3 interacting protein 1
chr12_+_48499883 0.52 ENST00000546755.1
ENST00000549366.1
ENST00000552792.1
PFKM
phosphofructokinase, muscle
chr6_+_138188351 0.51 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr10_+_99609996 0.51 ENST00000370602.1
GOLGA7B
golgin A7 family, member B
chr4_-_76957214 0.50 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr17_+_74381343 0.50 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr11_+_102188272 0.48 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr15_-_89438742 0.48 ENST00000562281.1
ENST00000562889.1
ENST00000359595.3
HAPLN3
hyaluronan and proteoglycan link protein 3
chr8_-_139926236 0.48 ENST00000303045.6
ENST00000435777.1
COL22A1
collagen, type XXII, alpha 1
chr2_+_97202480 0.47 ENST00000357485.3
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr17_-_56065540 0.46 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr9_-_136344197 0.46 ENST00000414172.1
ENST00000371897.4
SLC2A6
solute carrier family 2 (facilitated glucose transporter), member 6
chr22_+_31488433 0.44 ENST00000455608.1
SMTN
smoothelin
chr1_+_37940153 0.44 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr19_-_39735646 0.44 ENST00000413851.2
IFNL3
interferon, lambda 3
chr14_+_24616588 0.43 ENST00000324103.6
ENST00000559260.1
RNF31
ring finger protein 31
chr6_+_138188378 0.41 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_+_97203082 0.40 ENST00000454558.2
ARID5A
AT rich interactive domain 5A (MRF1-like)
chrX_-_21776281 0.40 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr12_+_48499252 0.39 ENST00000549003.1
ENST00000550924.1
PFKM
phosphofructokinase, muscle
chr6_+_138188551 0.39 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr9_+_134103496 0.38 ENST00000498010.1
ENST00000476004.1
ENST00000528406.1
NUP214
nucleoporin 214kDa
chr12_-_132905789 0.37 ENST00000328957.8
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr7_-_93520259 0.37 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr20_+_1115821 0.37 ENST00000435720.1
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr11_-_64570706 0.36 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr7_-_93520191 0.36 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr1_-_153935983 0.34 ENST00000537590.1
ENST00000356205.4
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr14_-_35873856 0.34 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr5_+_170846640 0.34 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr14_-_24615805 0.34 ENST00000560410.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr5_-_43313269 0.34 ENST00000511774.1
HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_-_4852332 0.33 ENST00000572383.1
PFN1
profilin 1
chr19_-_4182530 0.32 ENST00000601571.1
ENST00000601488.1
ENST00000305232.6
ENST00000381935.3
ENST00000337491.2
SIRT6
sirtuin 6
chr17_-_61777090 0.32 ENST00000578061.1
LIMD2
LIM domain containing 2
chr12_-_54813229 0.32 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr2_+_176957619 0.32 ENST00000392539.3
HOXD13
homeobox D13
chr3_-_111852061 0.31 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr4_+_74735102 0.31 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr19_+_42363917 0.31 ENST00000598742.1
RPS19
ribosomal protein S19
chr14_+_75988768 0.30 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr8_+_21899898 0.30 ENST00000518533.1
ENST00000359441.3
FGF17
fibroblast growth factor 17
chr11_-_74800799 0.30 ENST00000305159.3
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr1_-_153935938 0.30 ENST00000368621.1
ENST00000368623.3
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr6_-_150039170 0.29 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr6_+_31950150 0.29 ENST00000537134.1
C4A
complement component 4A (Rodgers blood group)
chr12_+_7053172 0.28 ENST00000229281.5
C12orf57
chromosome 12 open reading frame 57
chr7_+_100273736 0.28 ENST00000412215.1
ENST00000393924.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr12_+_7053228 0.28 ENST00000540506.2
C12orf57
chromosome 12 open reading frame 57
chr2_+_113735575 0.28 ENST00000376489.2
ENST00000259205.4
IL36G
interleukin 36, gamma
chr3_+_101546827 0.27 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_+_110453109 0.27 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr12_+_57623907 0.27 ENST00000553529.1
ENST00000554310.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr4_-_74864386 0.27 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr17_+_48638371 0.27 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr9_+_82187487 0.27 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr18_-_72920372 0.27 ENST00000581620.1
ENST00000582437.1
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr2_+_234602305 0.27 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr19_+_48898132 0.26 ENST00000263269.3
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr19_+_35940486 0.26 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr10_-_73533255 0.26 ENST00000394957.3
C10orf54
chromosome 10 open reading frame 54
chr19_-_4831701 0.26 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr2_-_217560248 0.26 ENST00000233813.4
IGFBP5
insulin-like growth factor binding protein 5
chr6_-_31613280 0.26 ENST00000453833.1
BAG6
BCL2-associated athanogene 6
chr10_+_12391685 0.25 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr9_+_82187630 0.25 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_+_7052974 0.25 ENST00000544681.1
ENST00000537087.1
C12orf57
chromosome 12 open reading frame 57
chr1_-_41950342 0.25 ENST00000372587.4
EDN2
endothelin 2
chr4_+_103422471 0.24 ENST00000226574.4
ENST00000394820.4
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr10_+_13141585 0.24 ENST00000378764.2
OPTN
optineurin
chr12_+_11802753 0.24 ENST00000396373.4
ETV6
ets variant 6
chr19_-_46272462 0.24 ENST00000317578.6
SIX5
SIX homeobox 5
chr20_+_35090150 0.23 ENST00000340491.4
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr19_+_40697514 0.23 ENST00000253055.3
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr11_+_102188224 0.23 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr2_+_228678550 0.22 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr19_+_18492973 0.22 ENST00000595973.2
GDF15
growth differentiation factor 15
chr10_+_13142075 0.22 ENST00000378757.2
ENST00000430081.1
ENST00000378752.3
ENST00000378748.3
OPTN
optineurin
chr12_-_48499826 0.22 ENST00000551798.1
SENP1
SUMO1/sentrin specific peptidase 1
chr1_-_36615051 0.22 ENST00000373163.1
TRAPPC3
trafficking protein particle complex 3
chr5_-_149792295 0.22 ENST00000518797.1
ENST00000524315.1
ENST00000009530.7
ENST00000377795.3
CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr4_-_134070250 0.21 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
RP11-9G1.3
chr6_+_29910301 0.21 ENST00000376809.5
ENST00000376802.2
HLA-A
major histocompatibility complex, class I, A
chr21_+_34775181 0.21 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr4_+_185395947 0.21 ENST00000605834.1
RP11-326I11.3
RP11-326I11.3
chr14_+_32798462 0.21 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr19_-_38747172 0.21 ENST00000347262.4
ENST00000591585.1
ENST00000301242.4
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr8_+_145582217 0.21 ENST00000530047.1
ENST00000527078.1
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr2_+_54951679 0.21 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr4_+_103422499 0.21 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr14_-_75078725 0.21 ENST00000556690.1
LTBP2
latent transforming growth factor beta binding protein 2
chr4_-_185395191 0.20 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr7_-_6570817 0.20 ENST00000435185.1
GRID2IP
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein
chr6_-_44233361 0.20 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr1_+_183441500 0.20 ENST00000456731.2
SMG7
SMG7 nonsense mediated mRNA decay factor
chrX_-_37706661 0.20 ENST00000432389.2
ENST00000378581.3
DYNLT3
dynein, light chain, Tctex-type 3
chr21_+_34775698 0.20 ENST00000381995.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_17638059 0.20 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr20_+_18488528 0.20 ENST00000377465.1
SEC23B
Sec23 homolog B (S. cerevisiae)
chr11_-_64570624 0.20 ENST00000439069.1
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr11_-_133826852 0.20 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr20_+_18488137 0.20 ENST00000450074.1
ENST00000262544.2
ENST00000336714.3
ENST00000377475.3
SEC23B
Sec23 homolog B (S. cerevisiae)
chr15_+_27216530 0.20 ENST00000555083.1
GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr9_-_117267717 0.19 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr6_+_135502466 0.19 ENST00000367814.4
MYB
v-myb avian myeloblastosis viral oncogene homolog
chr6_-_31138439 0.19 ENST00000259915.8
POU5F1
POU class 5 homeobox 1
chr1_-_153935791 0.19 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr2_+_202047843 0.19 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr12_+_57624059 0.19 ENST00000557427.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr10_-_7708918 0.19 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr16_+_28834531 0.19 ENST00000570200.1
ATXN2L
ataxin 2-like
chr2_+_208394794 0.19 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1
cAMP responsive element binding protein 1
chr3_+_57261859 0.18 ENST00000495803.1
ENST00000444459.1
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr19_-_13617247 0.18 ENST00000573710.2
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr14_+_103243813 0.18 ENST00000560371.1
ENST00000347662.4
ENST00000392745.2
ENST00000539721.1
ENST00000560463.1
TRAF3
TNF receptor-associated factor 3
chr14_+_24521202 0.18 ENST00000334420.7
ENST00000342740.5
LRRC16B
leucine rich repeat containing 16B
chr11_+_118754475 0.17 ENST00000292174.4
CXCR5
chemokine (C-X-C motif) receptor 5
chr19_+_42364313 0.17 ENST00000601492.1
ENST00000600467.1
ENST00000221975.2
RPS19
ribosomal protein S19
chr10_-_97050777 0.17 ENST00000329399.6
PDLIM1
PDZ and LIM domain 1
chr20_-_60294804 0.17 ENST00000317652.1
RP11-429E11.3
Uncharacterized protein
chr20_+_6748311 0.17 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr1_-_36615065 0.16 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr17_-_61819229 0.16 ENST00000447001.3
ENST00000392950.4
STRADA
STE20-related kinase adaptor alpha
chr17_-_17740287 0.16 ENST00000355815.4
ENST00000261646.5
SREBF1
sterol regulatory element binding transcription factor 1
chr1_+_183441600 0.16 ENST00000367537.3
SMG7
SMG7 nonsense mediated mRNA decay factor
chr22_-_39151995 0.16 ENST00000405018.1
ENST00000438058.1
SUN2
Sad1 and UNC84 domain containing 2
chr1_+_8021954 0.16 ENST00000377491.1
ENST00000377488.1
PARK7
parkinson protein 7
chr22_-_38349552 0.16 ENST00000422191.1
ENST00000249079.2
ENST00000418863.1
ENST00000403305.1
ENST00000403026.1
C22orf23
chromosome 22 open reading frame 23
chr6_+_106534192 0.16 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr1_+_28285973 0.16 ENST00000373884.5
XKR8
XK, Kell blood group complex subunit-related family, member 8
chr10_+_75668916 0.16 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr21_+_34775772 0.15 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr11_-_61596753 0.15 ENST00000448607.1
ENST00000421879.1
FADS1
fatty acid desaturase 1
chr9_+_127054254 0.15 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr10_+_13142225 0.15 ENST00000378747.3
OPTN
optineurin
chr11_-_44331679 0.15 ENST00000329255.3
ALX4
ALX homeobox 4
chr17_+_40719073 0.15 ENST00000435881.2
ENST00000246912.4
ENST00000346833.4
ENST00000591024.1
MLX
MLX, MAX dimerization protein
chr16_+_29823552 0.15 ENST00000300797.6
PRRT2
proline-rich transmembrane protein 2
chr1_-_155658085 0.15 ENST00000311573.5
ENST00000438245.2
YY1AP1
YY1 associated protein 1
chr12_-_58131931 0.15 ENST00000547588.1
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_+_31949801 0.15 ENST00000428956.2
ENST00000498271.1
C4A
complement component 4A (Rodgers blood group)
chr8_+_145582231 0.15 ENST00000526338.1
ENST00000402965.1
ENST00000534725.1
ENST00000532887.1
ENST00000329994.2
SLC52A2
solute carrier family 52 (riboflavin transporter), member 2
chr5_-_54468974 0.15 ENST00000381375.2
ENST00000296733.1
ENST00000322374.6
ENST00000334206.5
ENST00000331730.3
CDC20B
cell division cycle 20B
chr19_-_38746979 0.15 ENST00000591291.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr22_-_39151434 0.15 ENST00000439339.1
SUN2
Sad1 and UNC84 domain containing 2
chr20_-_62103862 0.15 ENST00000344462.4
ENST00000357249.2
ENST00000359125.2
ENST00000360480.3
ENST00000370224.1
ENST00000344425.5
ENST00000354587.3
ENST00000359689.1
KCNQ2
potassium voltage-gated channel, KQT-like subfamily, member 2
chr17_+_7590734 0.15 ENST00000457584.2
WRAP53
WD repeat containing, antisense to TP53
chr1_-_24469602 0.15 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr13_+_97874574 0.15 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr17_+_40440094 0.14 ENST00000546010.2
STAT5A
signal transducer and activator of transcription 5A
chr3_-_156878482 0.14 ENST00000295925.4
CCNL1
cyclin L1
chr12_+_49761224 0.14 ENST00000553127.1
ENST00000321898.6
SPATS2
spermatogenesis associated, serine-rich 2
chr7_+_101460882 0.14 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1
cut-like homeobox 1
chr17_+_47075023 0.14 ENST00000431824.2
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr19_-_5785630 0.14 ENST00000586012.1
ENST00000590343.1
CTB-54O9.9
DUS3L
Uncharacterized protein
dihydrouridine synthase 3-like (S. cerevisiae)
chr8_-_145582118 0.14 ENST00000455319.2
ENST00000331890.5
FBXL6
F-box and leucine-rich repeat protein 6
chr16_+_67282853 0.14 ENST00000299798.11
SLC9A5
solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
chr20_+_44746939 0.14 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr6_-_33168391 0.14 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr6_+_33168189 0.14 ENST00000444757.1
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr17_-_1419878 0.14 ENST00000449479.1
ENST00000477910.1
ENST00000542125.1
ENST00000575172.1
INPP5K
inositol polyphosphate-5-phosphatase K
chr12_-_48499591 0.14 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr16_+_50730910 0.14 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr1_+_155657737 0.14 ENST00000471642.2
ENST00000471214.1
DAP3
death associated protein 3
chr14_+_61789382 0.14 ENST00000555082.1
PRKCH
protein kinase C, eta
chr2_-_242447732 0.14 ENST00000439101.1
ENST00000424537.1
ENST00000401869.1
ENST00000436402.1
STK25
serine/threonine kinase 25
chrX_-_73072534 0.14 ENST00000429829.1
XIST
X inactive specific transcript (non-protein coding)
chr12_-_57504069 0.14 ENST00000543873.2
ENST00000554663.1
ENST00000557635.1
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr1_+_107683644 0.14 ENST00000370067.1
NTNG1
netrin G1
chr11_-_46142505 0.14 ENST00000524497.1
ENST00000418153.2
PHF21A
PHD finger protein 21A
chr19_+_45251804 0.14 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr19_+_42364460 0.13 ENST00000593863.1
RPS19
ribosomal protein S19
chr2_+_208394455 0.13 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr1_-_153935738 0.13 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_-_2706236 0.13 ENST00000401095.3
ENST00000574621.2
TTC34
tetratricopeptide repeat domain 34
chr1_-_156051789 0.13 ENST00000532414.2
MEX3A
mex-3 RNA binding family member A
chr20_-_2451395 0.13 ENST00000339610.6
ENST00000381342.2
ENST00000438552.2
SNRPB
small nuclear ribonucleoprotein polypeptides B and B1
chr5_-_178054014 0.13 ENST00000520957.1
CLK4
CDC-like kinase 4
chr6_+_144471643 0.13 ENST00000367568.4
STX11
syntaxin 11
chr19_+_35485682 0.13 ENST00000599564.1
GRAMD1A
GRAM domain containing 1A
chr17_-_61776522 0.13 ENST00000582055.1
LIMD2
LIM domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of NFKB1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.4 1.3 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.3 1.0 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.2 0.9 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.2 2.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.8 GO:0036343 psychomotor behavior(GO:0036343)
0.2 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.5 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.8 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 0.6 GO:0046967 cytosol to ER transport(GO:0046967)
0.2 0.6 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.2 0.9 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.1 0.4 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 0.4 GO:2000627 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 0.5 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.5 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.3 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 0.4 GO:0060584 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.4 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) histone H3-K9 deacetylation(GO:1990619)
0.1 1.3 GO:0060263 regulation of respiratory burst(GO:0060263)
0.1 0.6 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.4 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 0.6 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.4 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 0.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.2 GO:0045360 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.4 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.7 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.2 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.3 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.2 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.1 0.2 GO:0060129 regulation of calcium-independent cell-cell adhesion(GO:0051040) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.4 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.2 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.1 0.2 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 1.0 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 1.1 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.3 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.1 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116) hindlimb morphogenesis(GO:0035137)
0.0 0.1 GO:0060738 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092) primary prostatic bud elongation(GO:0060516) epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738) sclerotome development(GO:0061056)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.4 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0045359 positive regulation of interferon-beta biosynthetic process(GO:0045359)
0.0 0.1 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.3 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.2 GO:0033590 response to cobalamin(GO:0033590) cellular response to erythropoietin(GO:0036018)
0.0 0.1 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 1.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.0 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.4 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.3 GO:0071372 response to vitamin E(GO:0033197) cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 2.1 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
0.0 0.1 GO:2001151 regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.3 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.5 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.0 0.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.6 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.1 GO:2001038 regulation of cellular response to drug(GO:2001038)
0.0 0.5 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.0 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.0 0.2 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.0 0.2 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.9 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.3 GO:0097194 execution phase of apoptosis(GO:0097194)
0.0 0.0 GO:0017143 insecticide metabolic process(GO:0017143)
0.0 0.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.5 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 2.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 1.1 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0031933 telomeric heterochromatin(GO:0031933)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 0.7 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.3 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.8 GO:0070552 BRISC complex(GO:0070552)
0.1 0.4 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.4 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.4 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.0 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.5 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.5 GO:0097342 ripoptosome(GO:0097342)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 1.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.4 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.0 GO:0035101 FACT complex(GO:0035101)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.7 GO:0046979 TAP2 binding(GO:0046979)
0.1 1.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0032129 histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
0.1 0.3 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.6 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.1 0.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.8 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.4 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.5 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.2 GO:0045485 omega-6 fatty acid desaturase activity(GO:0045485)
0.1 0.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 2.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.4 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.7 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0004904 interferon receptor activity(GO:0004904)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.8 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0042577 lipid phosphatase activity(GO:0042577)
0.0 0.2 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.6 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.0 0.1 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 3.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.1 0.3 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 1.8 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.6 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 2.1 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 2.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis