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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for NFE2L1
Z-value: 1.23
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Transcription factors associated with NFE2L1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| NFE2L1 | hg19_v2_chr17_+_46133307_46133348 | -0.91 | 8.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_57308979 Show fit | 1.24 |
ENST00000457912.1
|
smoothelin-like 1 |
|
| chr19_-_36019123 Show fit | 0.93 |
ENST00000588674.1
ENST00000452271.2 ENST00000518157.1 |
suprabasin |
|
| chr17_-_34207295 Show fit | 0.88 |
ENST00000463941.1
ENST00000293272.3 |
chemokine (C-C motif) ligand 5 |
|
| chr16_+_31044413 Show fit | 0.85 |
ENST00000394998.1
|
syntaxin 4 |
|
| chr2_-_158345341 Show fit | 0.84 |
ENST00000435117.1
|
cytohesin 1 interacting protein |
|
| chr10_-_10504285 Show fit | 0.69 |
ENST00000602311.1
|
RP11-271F18.4 |
|
| chr3_-_114790179 Show fit | 0.65 |
ENST00000462705.1
|
zinc finger and BTB domain containing 20 |
|
| chr19_-_44160768 Show fit | 0.60 |
ENST00000593447.1
|
plasminogen activator, urokinase receptor |
|
| chr18_-_2982869 Show fit | 0.58 |
ENST00000584915.1
|
lipin 2 |
|
| chr15_+_89182178 Show fit | 0.56 |
ENST00000559876.1
|
interferon stimulated exonuclease gene 20kDa |
Network of associatons between targets according to the STRING database.
First level regulatory network of NFE2L1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.6 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
| 0.4 | 1.3 | GO:1902568 | regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
| 0.1 | 1.0 | GO:0038195 | urokinase plasminogen activator signaling pathway(GO:0038195) |
| 0.3 | 0.9 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 0.1 | 0.9 | GO:0042905 | 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905) |
| 0.0 | 0.7 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.0 | 0.7 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.7 | GO:0045907 | positive regulation of vasoconstriction(GO:0045907) |
| 0.1 | 0.6 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.0 | 0.6 | GO:0015865 | purine nucleotide transport(GO:0015865) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | GO:0015030 | Cajal body(GO:0015030) |
| 0.0 | 1.5 | GO:0031430 | M band(GO:0031430) |
| 0.1 | 1.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 1.0 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.0 | 0.6 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.0 | 0.6 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 0.5 | GO:0033186 | CAF-1 complex(GO:0033186) |
| 0.0 | 0.5 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.0 | 0.5 | GO:0005639 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
| 0.1 | 0.4 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 1.6 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.3 | 1.3 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.1 | 1.0 | GO:0030377 | urokinase plasminogen activator receptor activity(GO:0030377) |
| 0.2 | 0.9 | GO:0031726 | CCR1 chemokine receptor binding(GO:0031726) |
| 0.1 | 0.9 | GO:0004022 | alcohol dehydrogenase (NAD) activity(GO:0004022) |
| 0.1 | 0.7 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 0.1 | 0.6 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.0 | 0.6 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.0 | 0.6 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.1 | 0.5 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.4 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 1.4 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 1.2 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 1.0 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.7 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.0 | 0.7 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.4 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.0 | 0.3 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 0.3 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |