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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for NFATC1

Z-value: 0.92

Motif logo

Transcription factors associated with NFATC1

Gene Symbol Gene ID Gene Info
ENSG00000131196.13 nuclear factor of activated T cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFATC1hg19_v2_chr18_+_77160282_771603920.356.5e-01Click!

Activity profile of NFATC1 motif

Sorted Z-values of NFATC1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_78354243 0.44 ENST00000294624.8
nexilin (F actin binding protein)
chr3_+_184530173 0.43 ENST00000453056.1
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr11_-_110167331 0.37 ENST00000534683.1
radixin
chr12_+_20968608 0.36 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr13_-_67804445 0.36 ENST00000456367.1
ENST00000377861.3
ENST00000544246.1
protocadherin 9
chr3_-_158390282 0.32 ENST00000264265.3
latexin
chr2_+_46926326 0.32 ENST00000394861.2
suppressor of cytokine signaling 5
chr3_+_152017924 0.32 ENST00000465907.2
ENST00000492948.1
ENST00000485509.1
ENST00000464596.1
muscleblind-like splicing regulator 1
chr1_+_87595433 0.32 ENST00000469312.2
ENST00000490006.2
long intergenic non-protein coding RNA 1140
chr7_-_38969150 0.30 ENST00000418457.2
vacuolar protein sorting 41 homolog (S. cerevisiae)
chr21_-_35899113 0.29 ENST00000492600.1
ENST00000481448.1
ENST00000381132.2
regulator of calcineurin 1
chr11_-_64660916 0.29 ENST00000413053.1
microRNA 194-2
chr1_+_235491714 0.28 ENST00000471812.1
ENST00000358966.2
ENST00000282841.5
ENST00000391855.2
geranylgeranyl diphosphate synthase 1
chrX_-_84634737 0.28 ENST00000262753.4
premature ovarian failure, 1B
chr5_+_49962495 0.27 ENST00000515175.1
poly (ADP-ribose) polymerase family, member 8
chr14_-_92413353 0.26 ENST00000556154.1
fibulin 5
chr15_+_52155001 0.26 ENST00000544199.1
tropomodulin 3 (ubiquitous)
chr2_+_201390843 0.26 ENST00000357799.4
ENST00000409203.3
shugoshin-like 2 (S. pombe)
chr11_-_110167352 0.24 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
radixin
chr19_-_30199516 0.24 ENST00000591243.1
chromosome 19 open reading frame 12
chr10_-_27149904 0.24 ENST00000376166.1
ENST00000376138.3
ENST00000355394.4
ENST00000346832.5
ENST00000376134.3
ENST00000376137.4
ENST00000536334.1
ENST00000490841.2
abl-interactor 1
chr9_-_19065082 0.24 ENST00000415524.1
HAUS augmin-like complex, subunit 6
chr13_-_41111323 0.24 ENST00000595486.1
Uncharacterized protein
chr1_+_186649754 0.24 ENST00000608917.1
RP5-973M2.2
chr10_-_105212141 0.23 ENST00000369788.3
calcium homeostasis modulator 2
chr3_+_178866199 0.23 ENST00000263967.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr17_-_46657473 0.23 ENST00000332503.5
homeobox B4
chr17_-_46692457 0.23 ENST00000468443.1
homeobox B8
chr3_-_50360165 0.22 ENST00000428028.1
hyaluronoglucosaminidase 2
chr14_-_92247032 0.22 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
catsper channel auxiliary subunit beta
chr4_+_159131346 0.21 ENST00000508243.1
ENST00000296529.6
transmembrane protein 144
chr9_-_20621834 0.21 ENST00000429426.2
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr3_+_151986709 0.21 ENST00000495875.2
ENST00000493459.1
ENST00000324210.5
ENST00000459747.1
muscleblind-like splicing regulator 1
chr3_+_69134124 0.21 ENST00000478935.1
ADP-ribosylation-like factor 6 interacting protein 5
chr10_+_94590910 0.21 ENST00000371547.4
exocyst complex component 6
chr13_+_73629107 0.21 ENST00000539231.1
Kruppel-like factor 5 (intestinal)
chr10_-_27149851 0.20 ENST00000376142.2
ENST00000359188.4
ENST00000376139.2
ENST00000376160.1
abl-interactor 1
chr3_+_152017360 0.20 ENST00000485910.1
ENST00000463374.1
muscleblind-like splicing regulator 1
chr13_+_96085847 0.19 ENST00000376873.3
claudin 10
chr18_+_52258390 0.19 ENST00000321600.1
dynactin associated protein
chr5_-_41510725 0.19 ENST00000328457.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr1_+_167298281 0.19 ENST00000367862.5
POU class 2 homeobox 1
chr3_+_157261116 0.19 ENST00000468043.1
ENST00000459838.1
ENST00000461040.1
ENST00000449199.2
ENST00000426338.2
chromosome 3 open reading frame 55
chr18_-_25739260 0.19 ENST00000413878.1
cadherin 2, type 1, N-cadherin (neuronal)
chr3_-_182817297 0.19 ENST00000539926.1
ENST00000476176.1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chrX_+_133941218 0.19 ENST00000370784.4
ENST00000370785.3
family with sequence similarity 122C
chr9_-_20622478 0.19 ENST00000355930.6
ENST00000380338.4
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr10_-_63995871 0.18 ENST00000315289.2
rhotekin 2
chr6_+_22221010 0.18 ENST00000567753.1
RP11-524C21.2
chr9_+_22646189 0.18 ENST00000436786.1
RP11-399D6.2
chr14_-_35591433 0.18 ENST00000261475.5
ENST00000555644.1
protein phosphatase 2, regulatory subunit B'', gamma
chr5_-_73937244 0.18 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr15_+_93443419 0.18 ENST00000557381.1
ENST00000420239.2
chromodomain helicase DNA binding protein 2
chr15_+_23255242 0.18 ENST00000450802.3
golgin A8 family, member I
chr1_-_244006528 0.17 ENST00000336199.5
ENST00000263826.5
v-akt murine thymoma viral oncogene homolog 3
chr12_+_50366620 0.17 ENST00000315520.5
aquaporin 6, kidney specific
chr8_-_95274536 0.17 ENST00000297596.2
ENST00000396194.2
GTP binding protein overexpressed in skeletal muscle
chr1_+_235492300 0.17 ENST00000476121.1
ENST00000497327.1
geranylgeranyl diphosphate synthase 1
chr6_+_135818979 0.17 ENST00000421378.2
ENST00000579057.1
ENST00000436554.1
ENST00000438618.2
long intergenic non-protein coding RNA 271
chr18_+_13382553 0.17 ENST00000586222.1
low density lipoprotein receptor class A domain containing 4
chr2_-_230786032 0.17 ENST00000428959.1
thyroid hormone receptor interactor 12
chr18_+_61575200 0.17 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr7_-_105221898 0.17 ENST00000486180.1
ENST00000485614.1
ENST00000480514.1
EF-hand calcium binding domain 10
chr13_-_76056250 0.17 ENST00000377636.3
ENST00000431480.2
ENST00000377625.2
ENST00000425511.1
TBC1 domain family, member 4
chr12_+_96588368 0.17 ENST00000547860.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chrX_-_154255143 0.16 ENST00000453950.1
ENST00000423959.1
coagulation factor VIII, procoagulant component
chr1_-_36020531 0.16 ENST00000440579.1
ENST00000494948.1
KIAA0319-like
chr5_-_39203093 0.15 ENST00000515010.1
FYN binding protein
chr1_+_22351977 0.15 ENST00000420503.1
ENST00000416769.1
ENST00000404210.2
long intergenic non-protein coding RNA 339
chr8_+_38831683 0.15 ENST00000302495.4
HtrA serine peptidase 4
chr7_-_151217166 0.15 ENST00000496004.1
Ras homolog enriched in brain
chr12_-_50616382 0.15 ENST00000552783.1
LIM domain and actin binding 1
chr14_+_90864504 0.15 ENST00000544280.2
calmodulin 1 (phosphorylase kinase, delta)
chr9_-_14314518 0.15 ENST00000397581.2
nuclear factor I/B
chr10_-_27149792 0.15 ENST00000376140.3
ENST00000376170.4
abl-interactor 1
chr5_-_7869108 0.15 ENST00000264669.5
ENST00000507572.1
ENST00000504695.1
FAST kinase domains 3
chr2_+_178977143 0.15 ENST00000286070.5
RNA binding motif protein 45
chr19_+_41509851 0.15 ENST00000593831.1
ENST00000330446.5
cytochrome P450, family 2, subfamily B, polypeptide 6
chr1_+_82266053 0.15 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
latrophilin 2
chr5_-_41510656 0.15 ENST00000377801.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr6_-_136871957 0.15 ENST00000354570.3
microtubule-associated protein 7
chr12_-_91573132 0.15 ENST00000550563.1
ENST00000546370.1
decorin
chr15_+_63354769 0.15 ENST00000558910.1
tropomyosin 1 (alpha)
chr12_-_50616122 0.14 ENST00000552823.1
ENST00000552909.1
LIM domain and actin binding 1
chr5_-_111093759 0.14 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
neuronal regeneration related protein
chr1_+_55013889 0.14 ENST00000343744.2
ENST00000371316.3
acyl-CoA thioesterase 11
chr7_+_95171457 0.14 ENST00000601424.1
Protein LOC100996577
chr10_-_121296045 0.14 ENST00000392865.1
regulator of G-protein signaling 10
chr12_-_11150474 0.14 ENST00000538986.1
taste receptor, type 2, member 20
chr1_-_85462762 0.14 ENST00000284027.5
mucolipin 2
chr14_+_51026844 0.14 ENST00000554886.1
atlastin GTPase 1
chr4_-_159094194 0.14 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
family with sequence similarity 198, member B
chr10_+_22610124 0.14 ENST00000376663.3
BMI1 polycomb ring finger oncogene
chr12_-_92536433 0.14 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
chromosome 12 open reading frame 79
chr11_+_11863579 0.14 ENST00000399455.2
ubiquitin specific peptidase 47
chr2_-_228244013 0.14 ENST00000304568.3
transmembrane 4 L six family member 20
chr7_-_156803329 0.14 ENST00000252971.6
motor neuron and pancreas homeobox 1
chr3_+_119814070 0.14 ENST00000469070.1
RP11-18H7.1
chr11_+_65190245 0.14 ENST00000499732.1
ENST00000501122.2
ENST00000601801.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr10_-_65028938 0.13 ENST00000402544.1
jumonji domain containing 1C
chr11_+_11863500 0.13 ENST00000527733.1
ENST00000539466.1
ubiquitin specific peptidase 47
chr17_-_49124230 0.13 ENST00000510283.1
ENST00000510855.1
sperm associated antigen 9
chr2_+_75061108 0.13 ENST00000290573.2
hexokinase 2
chr1_+_61548225 0.13 ENST00000371187.3
nuclear factor I/A
chr8_-_17555164 0.13 ENST00000297488.6
microtubule associated tumor suppressor 1
chr12_+_69201923 0.13 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase
chr10_-_92681033 0.13 ENST00000371697.3
ankyrin repeat domain 1 (cardiac muscle)
chr12_+_26111823 0.13 ENST00000381352.3
ENST00000535907.1
ENST00000405154.2
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr14_+_32547434 0.13 ENST00000556191.1
ENST00000554090.1
Rho GTPase activating protein 5
chr10_-_65028817 0.13 ENST00000542921.1
jumonji domain containing 1C
chr10_-_105212059 0.13 ENST00000260743.5
calcium homeostasis modulator 2
chr8_-_30002179 0.13 ENST00000320542.3
membrane bound O-acyltransferase domain containing 4
chr3_+_148447887 0.13 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
angiotensin II receptor, type 1
chr9_-_14314566 0.13 ENST00000397579.2
nuclear factor I/B
chr14_+_35591020 0.13 ENST00000603611.1
KIAA0391
chr8_+_92082424 0.13 ENST00000285420.4
ENST00000404789.3
OTU domain containing 6B
chr14_-_54418598 0.13 ENST00000609748.1
ENST00000558961.1
bone morphogenetic protein 4
chr12_+_54447637 0.12 ENST00000609810.1
ENST00000430889.2
homeobox C4
Homeobox protein Hox-C4
chr13_+_37581115 0.12 ENST00000481013.1
exosome component 8
chr3_+_140981456 0.12 ENST00000504264.1
acid phosphatase-like 2
chr17_+_39411636 0.12 ENST00000394008.1
keratin associated protein 9-9
chr4_-_38806404 0.12 ENST00000308979.2
ENST00000505940.1
ENST00000515861.1
toll-like receptor 1
chr1_+_92632542 0.12 ENST00000409154.4
ENST00000370378.4
KIAA1107
chrY_+_15017624 0.12 ENST00000440554.1
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr12_+_104359614 0.12 ENST00000266775.9
ENST00000544861.1
thymine-DNA glycosylase
chr1_-_186649543 0.12 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr1_+_15853308 0.12 ENST00000375838.1
ENST00000375847.3
ENST00000375849.1
DnaJ (Hsp40) homolog, subfamily C, member 16
chr7_+_76091775 0.12 ENST00000442516.1
deltex homolog 2 (Drosophila)
chr13_-_99174252 0.12 ENST00000376547.3
serine/threonine kinase 24
chr7_-_103848405 0.12 ENST00000447452.2
ENST00000545943.1
ENST00000297431.4
origin recognition complex, subunit 5
chr5_+_135496675 0.12 ENST00000507637.1
SMAD family member 5
chr3_+_69134080 0.11 ENST00000273258.3
ADP-ribosylation-like factor 6 interacting protein 5
chr16_-_66952779 0.11 ENST00000570262.1
ENST00000394055.3
ENST00000299752.4
cadherin 16, KSP-cadherin
chr10_-_27443294 0.11 ENST00000396296.3
ENST00000375972.3
ENST00000376016.3
ENST00000491542.2
YME1-like 1 ATPase
chr1_+_180601139 0.11 ENST00000367590.4
ENST00000367589.3
xenotropic and polytropic retrovirus receptor 1
chr5_+_75904950 0.11 ENST00000502745.1
IQ motif containing GTPase activating protein 2
chr6_-_64029879 0.11 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
lengsin, lens protein with glutamine synthetase domain
chr10_+_43932553 0.11 ENST00000456416.1
ENST00000437590.2
ENST00000451167.1
zinc finger protein 487
chr14_-_30396948 0.11 ENST00000331968.5
protein kinase D1
chr2_+_33701707 0.11 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_140261703 0.11 ENST00000409494.1
ENST00000289272.2
protocadherin alpha 13
chr12_+_26205496 0.11 ENST00000537946.1
ENST00000541218.1
ENST00000282884.9
ENST00000545413.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr2_-_178937478 0.11 ENST00000286063.6
phosphodiesterase 11A
chr2_+_172950227 0.11 ENST00000341900.6
distal-less homeobox 1
chr1_+_61548374 0.11 ENST00000485903.2
ENST00000371185.2
ENST00000371184.2
nuclear factor I/A
chr1_-_77685084 0.11 ENST00000370812.3
ENST00000359130.1
ENST00000445065.1
ENST00000370813.5
phosphatidylinositol glycan anchor biosynthesis, class K
chr20_+_55204351 0.10 ENST00000201031.2
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr4_+_39046615 0.10 ENST00000261425.3
ENST00000508137.2
kelch-like family member 5
chr4_-_153274078 0.10 ENST00000263981.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr20_-_43589109 0.10 ENST00000372813.3
translocase of outer mitochondrial membrane 34
chrX_-_119763835 0.10 ENST00000371313.2
ENST00000304661.5
C1GALT1-specific chaperone 1
chr7_-_83824449 0.10 ENST00000420047.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_-_46759138 0.10 ENST00000377879.3
chromosome X open reading frame 31
chr3_+_25469724 0.10 ENST00000437042.2
retinoic acid receptor, beta
chr15_+_32885657 0.10 ENST00000448387.2
ENST00000569659.1
golgin A8 family, member N
chr5_+_118690466 0.10 ENST00000503646.1
tumor necrosis factor, alpha-induced protein 8
chr16_-_69418649 0.10 ENST00000566257.1
telomeric repeat binding factor 2
chr9_+_22446814 0.10 ENST00000325870.2
DMRT-like family A1
chr3_-_182817367 0.10 ENST00000265594.4
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr4_-_52883786 0.10 ENST00000343457.3
leucine rich repeat containing 66
chr10_-_27443155 0.10 ENST00000427324.1
ENST00000326799.3
YME1-like 1 ATPase
chr2_+_33701684 0.10 ENST00000442390.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chrX_-_48827976 0.10 ENST00000218176.3
potassium voltage-gated channel, Shal-related subfamily, member 1
chr17_-_40264321 0.10 ENST00000430773.1
ENST00000413196.2
DEXH (Asp-Glu-X-His) box polypeptide 58
chr11_-_75062829 0.10 ENST00000393505.4
arrestin, beta 1
chr11_+_130542851 0.10 ENST00000317019.2
chromosome 11 open reading frame 44
chr22_-_41215328 0.09 ENST00000434185.1
ENST00000435456.2
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chrX_-_40506766 0.09 ENST00000378421.1
ENST00000440784.2
ENST00000327877.5
ENST00000378426.1
ENST00000378418.2
chromosome X open reading frame 38
chr21_-_35340759 0.09 ENST00000607953.1
AP000569.9
chr13_-_108867101 0.09 ENST00000356922.4
ligase IV, DNA, ATP-dependent
chr16_-_66952742 0.09 ENST00000565235.2
ENST00000568632.1
ENST00000565796.1
cadherin 16, KSP-cadherin
chr14_+_35591509 0.09 ENST00000604073.1
KIAA0391
chr15_-_35280426 0.09 ENST00000559564.1
ENST00000356321.4
zinc finger protein 770
chr19_-_4722780 0.09 ENST00000600621.1
dipeptidyl-peptidase 9
chr11_+_74862032 0.09 ENST00000289575.5
ENST00000341411.4
solute carrier organic anion transporter family, member 2B1
chr15_+_82722225 0.09 ENST00000300515.8
golgin A6 family-like 9
chr15_+_83098710 0.09 ENST00000561062.1
ENST00000358583.3
golgin A6 family-like 20
chr1_-_94703118 0.09 ENST00000260526.6
ENST00000370217.3
Rho GTPase activating protein 29
chr4_-_155471528 0.09 ENST00000302078.5
ENST00000499023.2
pleiotropic regulator 1
chr2_+_46926048 0.09 ENST00000306503.5
suppressor of cytokine signaling 5
chr8_-_141774467 0.09 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr1_-_151798546 0.08 ENST00000356728.6
RAR-related orphan receptor C
chr7_-_80548493 0.08 ENST00000536800.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr14_-_35591156 0.08 ENST00000554361.1
protein phosphatase 2, regulatory subunit B'', gamma
chr5_-_78808617 0.08 ENST00000282260.6
ENST00000508576.1
ENST00000535690.1
homer homolog 1 (Drosophila)
chr12_-_15815626 0.08 ENST00000540613.1
epidermal growth factor receptor pathway substrate 8
chr15_-_59981479 0.08 ENST00000607373.1
BCL2/adenovirus E1B 19kDa interacting protein 2
chr4_+_41614909 0.08 ENST00000509454.1
ENST00000396595.3
ENST00000381753.4
LIM and calponin homology domains 1
chr5_+_33440802 0.08 ENST00000502553.1
ENST00000514259.1
ENST00000265112.3
threonyl-tRNA synthetase
chr22_-_43398442 0.08 ENST00000422336.1
protein kinase C and casein kinase substrate in neurons 2
chr11_+_10477733 0.08 ENST00000528723.1
adenosine monophosphate deaminase 3
chr20_+_36149602 0.08 ENST00000062104.2
ENST00000346199.2
neuronatin
chr11_-_102401469 0.08 ENST00000260227.4
matrix metallopeptidase 7 (matrilysin, uterine)
chr4_-_11431389 0.08 ENST00000002596.5
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr5_+_32788945 0.08 ENST00000326958.1
AC026703.1
chr3_+_88188254 0.08 ENST00000309495.5
zinc finger protein 654
chr1_+_174846570 0.08 ENST00000392064.2
RAB GTPase activating protein 1-like
chr1_+_45274154 0.08 ENST00000450269.1
ENST00000453418.1
ENST00000409335.2
BTB (POZ) domain containing 19
chr2_-_159237472 0.08 ENST00000409187.1
coiled-coil domain containing 148
chr5_+_33441053 0.08 ENST00000541634.1
ENST00000455217.2
ENST00000414361.2
threonyl-tRNA synthetase

Network of associatons between targets according to the STRING database.

First level regulatory network of NFATC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033385 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.6 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.1 0.1 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.5 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.2 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.4 GO:0045629 positive regulation of T-helper 1 cell differentiation(GO:0045627) negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.2 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.0 0.1 GO:0070340 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.2 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.3 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.1 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.2 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.1 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.5 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.6 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.3 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.2 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.0 GO:0072190 ureter urothelium development(GO:0072190)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0090646 mitochondrial tRNA processing(GO:0090646)
0.0 0.6 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:2000809 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.0 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.0 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.0 0.3 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.0 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.1 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.0 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290) formaldehyde metabolic process(GO:0046292)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.0 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.0 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740) positive regulation of thymocyte migration(GO:2000412) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 0.6 GO:0051286 cell tip(GO:0051286)
0.0 0.3 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.1 GO:0020003 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.0 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.2 GO:0015228 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.3 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.2 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.2 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.5 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.0 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 ST GA13 PATHWAY G alpha 13 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol