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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for MYF6
Z-value: 1.27
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Transcription factors associated with MYF6
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_7005785 Show fit | 1.32 |
ENST00000256722.5
ENST00000404168.1 ENST00000458098.1 |
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial |
|
| chr8_-_23712312 Show fit | 1.27 |
ENST00000290271.2
|
stanniocalcin 1 |
|
| chr17_+_68165657 Show fit | 1.26 |
ENST00000243457.3
|
potassium inwardly-rectifying channel, subfamily J, member 2 |
|
| chr5_-_139422654 Show fit | 0.97 |
ENST00000289409.4
ENST00000358522.3 ENST00000378238.4 ENST00000289422.7 ENST00000361474.1 ENST00000545385.1 ENST00000394770.1 ENST00000541337.1 |
neuregulin 2 |
|
| chr4_+_89299994 Show fit | 0.97 |
ENST00000264346.7
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
|
| chr4_+_89299885 Show fit | 0.94 |
ENST00000380265.5
ENST00000273960.3 |
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
|
| chr8_-_145086922 Show fit | 0.89 |
ENST00000530478.1
|
poly (ADP-ribose) polymerase family, member 10 |
|
| chr4_+_7194247 Show fit | 0.79 |
ENST00000507866.2
|
sortilin-related VPS10 domain containing receptor 2 |
|
| chr11_-_627143 Show fit | 0.73 |
ENST00000176195.3
|
secretin |
|
| chr9_-_131940526 Show fit | 0.69 |
ENST00000372491.2
|
immediate early response 5-like |
Network of associatons between targets according to the STRING database.
First level regulatory network of MYF6
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.5 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 1.5 | GO:0034465 | response to carbon monoxide(GO:0034465) |
| 0.0 | 1.4 | GO:0010507 | negative regulation of autophagy(GO:0010507) |
| 0.3 | 1.3 | GO:0009138 | pyrimidine nucleoside diphosphate metabolic process(GO:0009138) |
| 0.3 | 1.3 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.3 | 1.2 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) |
| 0.1 | 1.1 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
| 0.0 | 1.1 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.1 | 1.0 | GO:0006705 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
| 0.0 | 1.0 | GO:0097067 | cellular response to thyroid hormone stimulus(GO:0097067) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.8 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 1.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.2 | 1.1 | GO:0043260 | laminin-11 complex(GO:0043260) |
| 0.0 | 0.9 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.1 | 0.8 | GO:0071438 | invadopodium membrane(GO:0071438) |
| 0.1 | 0.7 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.1 | 0.5 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.1 | 0.4 | GO:0034667 | integrin alpha3-beta1 complex(GO:0034667) |
| 0.0 | 0.4 | GO:0005610 | laminin-5 complex(GO:0005610) |
| 0.0 | 0.4 | GO:0016272 | prefoldin complex(GO:0016272) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.5 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
| 0.3 | 1.3 | GO:0009041 | uridylate kinase activity(GO:0009041) |
| 0.0 | 1.3 | GO:0005179 | hormone activity(GO:0005179) |
| 0.3 | 1.2 | GO:0086062 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062) |
| 0.0 | 1.2 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 1.1 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.0 | 1.1 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 1.0 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.0 | 1.0 | GO:0070888 | E-box binding(GO:0070888) |
| 0.1 | 0.9 | GO:0004645 | phosphorylase activity(GO:0004645) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.0 | 1.2 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 1.1 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.0 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.9 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.0 | 0.7 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.0 | 0.5 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 0.5 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.0 | 0.2 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 1.2 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 1.0 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.1 | 0.9 | REACTOME ENDOGENOUS STEROLS | Genes involved in Endogenous sterols |
| 0.0 | 0.8 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.0 | 0.6 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.5 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.0 | 0.5 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.0 | 0.5 | REACTOME GLUCAGON TYPE LIGAND RECEPTORS | Genes involved in Glucagon-type ligand receptors |