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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for MESP1

Z-value: 0.69

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Transcription factors associated with MESP1

Gene Symbol Gene ID Gene Info
MESP1
ENSG00000166823.5 mesoderm posterior bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
MESP1hg19_v2_chr15_-_90294523_902945410.928.0e-02Click!

Activity profile of MESP1 motif

Sorted Z-values of MESP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_46035187 0.86 ENST00000300557.2
PRR15L
proline rich 15-like
chr2_+_47596287 0.59 ENST00000263735.4
EPCAM
epithelial cell adhesion molecule
chr3_-_182833863 0.57 ENST00000492597.1
MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr10_-_93392811 0.42 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr15_+_82555125 0.42 ENST00000566205.1
ENST00000339465.5
ENST00000569120.1
ENST00000566861.1
FAM154B
family with sequence similarity 154, member B
chr19_-_47735918 0.40 ENST00000449228.1
ENST00000300880.7
ENST00000341983.4
BBC3
BCL2 binding component 3
chr20_+_43029911 0.39 ENST00000443598.2
ENST00000316099.4
ENST00000415691.2
HNF4A
hepatocyte nuclear factor 4, alpha
chr11_+_73358594 0.37 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr7_+_16793160 0.37 ENST00000262067.4
TSPAN13
tetraspanin 13
chr3_-_112356944 0.36 ENST00000461431.1
CCDC80
coiled-coil domain containing 80
chr11_+_86511569 0.36 ENST00000441050.1
PRSS23
protease, serine, 23
chr11_+_827553 0.36 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr11_-_86383650 0.36 ENST00000526944.1
ENST00000530335.1
ENST00000543262.1
ENST00000524826.1
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr3_+_186330712 0.36 ENST00000411641.2
ENST00000273784.5
AHSG
alpha-2-HS-glycoprotein
chr11_-_17410629 0.36 ENST00000526912.1
KCNJ11
potassium inwardly-rectifying channel, subfamily J, member 11
chr1_+_150954493 0.35 ENST00000368947.4
ANXA9
annexin A9
chr6_-_130031358 0.34 ENST00000368149.2
ARHGAP18
Rho GTPase activating protein 18
chr17_+_37894179 0.34 ENST00000577695.1
ENST00000309156.4
ENST00000309185.3
GRB7
growth factor receptor-bound protein 7
chr11_+_86502085 0.33 ENST00000527521.1
PRSS23
protease, serine, 23
chr3_+_167453026 0.33 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr19_+_48673949 0.32 ENST00000328759.7
C19orf68
chromosome 19 open reading frame 68
chr2_+_109065634 0.32 ENST00000409821.1
GCC2
GRIP and coiled-coil domain containing 2
chr19_-_47137942 0.32 ENST00000300873.4
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr16_-_21289627 0.32 ENST00000396023.2
ENST00000415987.2
CRYM
crystallin, mu
chrX_+_70443050 0.31 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr10_+_103348031 0.31 ENST00000370151.4
ENST00000370147.1
ENST00000370148.2
DPCD
deleted in primary ciliary dyskinesia homolog (mouse)
chr8_+_98881268 0.31 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2
matrilin 2
chr3_+_167453493 0.31 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_+_38152462 0.31 ENST00000354545.2
RMDN2
regulator of microtubule dynamics 2
chr12_-_27167233 0.30 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3
transmembrane 7 superfamily member 3
chr14_+_31343747 0.30 ENST00000216361.4
ENST00000396618.3
ENST00000475087.1
COCH
cochlin
chr8_-_71520513 0.29 ENST00000262213.2
ENST00000536748.1
ENST00000518678.1
TRAM1
translocation associated membrane protein 1
chr11_+_47279155 0.29 ENST00000444396.1
ENST00000457932.1
ENST00000412937.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr12_+_52450298 0.29 ENST00000550582.2
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr1_+_154377669 0.28 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr4_-_76598296 0.28 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chrX_-_45710920 0.28 ENST00000456532.1
RP5-1158E12.3
RP5-1158E12.3
chr1_+_26438289 0.27 ENST00000374271.4
ENST00000374269.1
PDIK1L
PDLIM1 interacting kinase 1 like
chr6_+_159290917 0.26 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr3_-_197282821 0.26 ENST00000445160.2
ENST00000446746.1
ENST00000432819.1
ENST00000392379.1
ENST00000441275.1
ENST00000392378.2
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr12_-_25150409 0.26 ENST00000549262.1
C12orf77
chromosome 12 open reading frame 77
chr5_+_78532003 0.25 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr12_+_124457670 0.25 ENST00000539644.1
ZNF664
zinc finger protein 664
chr12_+_124457746 0.25 ENST00000392404.3
ENST00000538932.2
ENST00000337815.4
ENST00000540762.2
ZNF664
FAM101A
zinc finger protein 664
family with sequence similarity 101, member A
chr17_+_39411636 0.25 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr12_+_50497784 0.25 ENST00000548814.1
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr19_-_49565254 0.24 ENST00000593537.1
NTF4
neurotrophin 4
chr18_+_29077990 0.24 ENST00000261590.8
DSG2
desmoglein 2
chr17_-_27503770 0.24 ENST00000533112.1
MYO18A
myosin XVIIIA
chr2_+_205410723 0.24 ENST00000358768.2
ENST00000351153.1
ENST00000349953.3
PARD3B
par-3 family cell polarity regulator beta
chrX_+_40440146 0.24 ENST00000535539.1
ENST00000378438.4
ENST00000436783.1
ENST00000544975.1
ENST00000535777.1
ENST00000447485.1
ENST00000423649.1
ATP6AP2
ATPase, H+ transporting, lysosomal accessory protein 2
chr2_-_224702201 0.24 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr22_-_41842781 0.24 ENST00000434408.1
TOB2
transducer of ERBB2, 2
chr10_+_94608245 0.24 ENST00000443748.2
ENST00000260762.6
EXOC6
exocyst complex component 6
chr9_+_135937365 0.23 ENST00000372080.4
ENST00000351304.7
CEL
carboxyl ester lipase
chr14_+_38065052 0.23 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr14_+_75746664 0.23 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_105086056 0.23 ENST00000472644.2
ALCAM
activated leukocyte cell adhesion molecule
chr8_-_71519889 0.23 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr4_+_106816592 0.23 ENST00000379987.2
ENST00000453617.2
ENST00000427316.2
ENST00000514622.1
ENST00000305572.8
NPNT
nephronectin
chr4_+_26859300 0.23 ENST00000494628.2
STIM2
stromal interaction molecule 2
chr12_-_89919220 0.22 ENST00000549035.1
ENST00000393179.4
POC1B
POC1 centriolar protein B
chr7_-_95225768 0.22 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr14_-_67981916 0.22 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr17_-_39316983 0.22 ENST00000390661.3
KRTAP4-4
keratin associated protein 4-4
chrX_+_106163626 0.22 ENST00000336803.1
CLDN2
claudin 2
chr19_-_7939319 0.22 ENST00000539422.1
CTD-3193O13.9
Protein FLJ22184
chr17_+_37894570 0.22 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr5_-_180287663 0.21 ENST00000509066.1
ENST00000504225.1
ZFP62
ZFP62 zinc finger protein
chr14_+_75746781 0.21 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr2_+_205410516 0.21 ENST00000406610.2
ENST00000462231.1
PARD3B
par-3 family cell polarity regulator beta
chr4_+_37892682 0.21 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr3_-_158450475 0.21 ENST00000237696.5
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr17_+_39346139 0.21 ENST00000398470.1
ENST00000318329.5
KRTAP9-1
keratin associated protein 9-1
chr16_+_333152 0.21 ENST00000219406.6
ENST00000404312.1
ENST00000456379.1
PDIA2
protein disulfide isomerase family A, member 2
chr8_-_53626974 0.21 ENST00000435644.2
ENST00000518710.1
ENST00000025008.5
ENST00000517963.1
RB1CC1
RB1-inducible coiled-coil 1
chr17_+_42015654 0.21 ENST00000565120.1
RP11-527L4.2
Uncharacterized protein
chr3_+_16926441 0.21 ENST00000418129.2
ENST00000396755.2
PLCL2
phospholipase C-like 2
chr11_+_86511549 0.21 ENST00000533902.2
PRSS23
protease, serine, 23
chr12_-_74686314 0.21 ENST00000551210.1
ENST00000515416.2
ENST00000549905.1
RP11-81H3.2
RP11-81H3.2
chr1_+_95582881 0.21 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr1_+_60280458 0.21 ENST00000455990.1
ENST00000371208.3
HOOK1
hook microtubule-tethering protein 1
chrX_-_107019181 0.20 ENST00000315660.4
ENST00000372384.2
ENST00000502650.1
ENST00000506724.1
TSC22D3
TSC22 domain family, member 3
chr14_+_75746340 0.20 ENST00000555686.1
ENST00000555672.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr12_-_110318263 0.20 ENST00000318348.4
GLTP
glycolipid transfer protein
chr2_-_228028829 0.20 ENST00000396625.3
ENST00000329662.7
COL4A4
collagen, type IV, alpha 4
chr14_-_50999373 0.20 ENST00000554273.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr3_+_45636219 0.20 ENST00000273317.4
LIMD1
LIM domains containing 1
chr10_-_103347883 0.20 ENST00000339310.3
ENST00000370158.3
ENST00000299206.4
ENST00000456836.2
ENST00000413344.1
ENST00000429502.1
ENST00000430045.1
ENST00000370172.1
ENST00000436284.2
ENST00000370162.3
POLL
polymerase (DNA directed), lambda
chr7_-_21985656 0.20 ENST00000406877.3
CDCA7L
cell division cycle associated 7-like
chr3_+_105085734 0.20 ENST00000306107.5
ALCAM
activated leukocyte cell adhesion molecule
chr4_-_141348763 0.20 ENST00000509477.1
CLGN
calmegin
chr7_-_27170352 0.20 ENST00000428284.2
ENST00000360046.5
HOXA4
homeobox A4
chr11_+_125439176 0.20 ENST00000529812.1
EI24
etoposide induced 2.4
chr3_-_101395936 0.20 ENST00000461821.1
ZBTB11
zinc finger and BTB domain containing 11
chr17_+_73521763 0.19 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr11_-_1619524 0.19 ENST00000412090.1
KRTAP5-2
keratin associated protein 5-2
chr8_-_103876965 0.19 ENST00000337198.5
AZIN1
antizyme inhibitor 1
chr11_+_72281681 0.19 ENST00000450804.3
RP11-169D4.1
RP11-169D4.1
chr3_-_128294929 0.19 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr8_-_103876383 0.19 ENST00000347770.4
AZIN1
antizyme inhibitor 1
chr2_+_128293323 0.19 ENST00000389524.4
ENST00000428314.1
MYO7B
myosin VIIB
chr20_-_46041046 0.19 ENST00000437920.1
RP1-148H17.1
RP1-148H17.1
chr14_+_31343951 0.19 ENST00000556908.1
ENST00000555881.1
ENST00000460581.2
COCH
cochlin
chr1_+_228337553 0.19 ENST00000366714.2
GJC2
gap junction protein, gamma 2, 47kDa
chr2_-_175869936 0.19 ENST00000409900.3
CHN1
chimerin 1
chr5_-_43557129 0.19 ENST00000514514.1
ENST00000504075.1
ENST00000306846.3
ENST00000436644.2
PAIP1
poly(A) binding protein interacting protein 1
chr7_-_8302298 0.19 ENST00000446305.1
ICA1
islet cell autoantigen 1, 69kDa
chr19_+_54058073 0.19 ENST00000505949.1
ENST00000513265.1
ZNF331
zinc finger protein 331
chr19_+_16187085 0.19 ENST00000300933.4
TPM4
tropomyosin 4
chr3_-_178790057 0.19 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr19_+_7660716 0.19 ENST00000160298.4
ENST00000446248.2
CAMSAP3
calmodulin regulated spectrin-associated protein family, member 3
chr12_+_56473628 0.18 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
ERBB3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr8_+_104311059 0.18 ENST00000358755.4
ENST00000523739.1
ENST00000540287.1
FZD6
frizzled family receptor 6
chr1_+_24645865 0.18 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr5_-_95018660 0.18 ENST00000395899.3
ENST00000274432.8
SPATA9
spermatogenesis associated 9
chr16_-_4987065 0.18 ENST00000590782.2
ENST00000345988.2
PPL
periplakin
chr17_-_78194716 0.18 ENST00000576707.1
SGSH
N-sulfoglucosamine sulfohydrolase
chr11_-_102323489 0.18 ENST00000361236.3
TMEM123
transmembrane protein 123
chr13_+_88324870 0.18 ENST00000325089.6
SLITRK5
SLIT and NTRK-like family, member 5
chr2_-_232571621 0.17 ENST00000595658.1
MGC4771
MGC4771
chr16_-_30006922 0.17 ENST00000564026.1
HIRIP3
HIRA interacting protein 3
chr1_+_24646002 0.17 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr5_+_139055055 0.17 ENST00000511457.1
CXXC5
CXXC finger protein 5
chr7_-_120497178 0.17 ENST00000441017.1
ENST00000424710.1
ENST00000433758.1
TSPAN12
tetraspanin 12
chr3_+_122920847 0.17 ENST00000466519.1
ENST00000480631.1
ENST00000491366.1
ENST00000487572.1
SEC22A
SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
chr15_+_57210818 0.17 ENST00000438423.2
ENST00000267811.5
ENST00000452095.2
ENST00000559609.1
ENST00000333725.5
TCF12
transcription factor 12
chr2_+_30670077 0.17 ENST00000466477.1
ENST00000465200.1
ENST00000379509.3
ENST00000319406.4
ENST00000488144.1
ENST00000465538.1
ENST00000309052.4
ENST00000359433.1
LCLAT1
lysocardiolipin acyltransferase 1
chr8_+_38758737 0.17 ENST00000521746.1
ENST00000420274.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr6_-_33160231 0.17 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr19_+_37709076 0.17 ENST00000590503.1
ENST00000589413.1
ZNF383
zinc finger protein 383
chr14_-_38064198 0.17 ENST00000250448.2
FOXA1
forkhead box A1
chrX_-_67653614 0.17 ENST00000355520.5
OPHN1
oligophrenin 1
chr14_-_107083690 0.17 ENST00000455737.1
ENST00000390629.2
IGHV4-59
immunoglobulin heavy variable 4-59
chr17_-_7165662 0.17 ENST00000571881.2
ENST00000360325.7
CLDN7
claudin 7
chr6_-_41888814 0.17 ENST00000409060.1
ENST00000265350.4
MED20
mediator complex subunit 20
chr4_-_139163491 0.17 ENST00000280612.5
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr14_-_67981870 0.17 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr16_+_22524379 0.17 ENST00000536620.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr12_+_27849378 0.17 ENST00000310791.2
REP15
RAB15 effector protein
chr22_-_28392227 0.16 ENST00000431039.1
TTC28
tetratricopeptide repeat domain 28
chrX_-_63005405 0.16 ENST00000374878.1
ENST00000437457.2
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr8_-_103136481 0.16 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD
neurocalcin delta
chr9_+_91003271 0.16 ENST00000375859.3
ENST00000541629.1
SPIN1
spindlin 1
chr1_-_26185844 0.16 ENST00000538789.1
ENST00000374298.3
AUNIP
aurora kinase A and ninein interacting protein
chr2_+_220436917 0.16 ENST00000243786.2
INHA
inhibin, alpha
chr3_-_46068969 0.16 ENST00000542109.1
ENST00000395946.2
XCR1
chemokine (C motif) receptor 1
chr4_-_141348789 0.16 ENST00000414773.1
CLGN
calmegin
chr22_-_37882395 0.16 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr22_-_36018569 0.16 ENST00000419229.1
ENST00000406324.1
MB
myoglobin
chr2_-_157189180 0.16 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chrX_+_16804544 0.16 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr12_+_69202795 0.16 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr1_-_219615984 0.16 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr5_+_148737562 0.16 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr1_-_150669500 0.16 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr8_-_144654918 0.16 ENST00000529971.1
MROH6
maestro heat-like repeat family member 6
chr14_+_65170820 0.16 ENST00000555982.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_-_10920838 0.16 ENST00000503469.2
CTD-2003C8.2
CTD-2003C8.2
chr10_-_46342675 0.16 ENST00000492347.1
AGAP4
ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
chr10_-_118032697 0.16 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr1_+_24645807 0.16 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr6_+_35995552 0.16 ENST00000468133.1
MAPK14
mitogen-activated protein kinase 14
chr21_-_46131470 0.16 ENST00000323084.4
TSPEAR
thrombospondin-type laminin G domain and EAR repeats
chr12_+_69201923 0.16 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr2_-_99485825 0.15 ENST00000423771.1
KIAA1211L
KIAA1211-like
chr15_+_75640068 0.15 ENST00000565051.1
ENST00000564257.1
ENST00000567005.1
NEIL1
nei endonuclease VIII-like 1 (E. coli)
chr12_-_12419905 0.15 ENST00000535731.1
LRP6
low density lipoprotein receptor-related protein 6
chr12_+_50479101 0.15 ENST00000551966.1
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr5_-_43557791 0.15 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
PAIP1
poly(A) binding protein interacting protein 1
chr4_-_76598544 0.15 ENST00000515457.1
ENST00000357854.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr17_+_52978156 0.15 ENST00000348161.4
TOM1L1
target of myb1 (chicken)-like 1
chr14_-_50999307 0.15 ENST00000013125.4
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr6_+_44191507 0.15 ENST00000371724.1
ENST00000371713.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr4_+_3443614 0.15 ENST00000382774.3
ENST00000511533.1
HGFAC
HGF activator
chr6_+_35995531 0.15 ENST00000229794.4
MAPK14
mitogen-activated protein kinase 14
chr5_-_89825328 0.15 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr1_+_57110972 0.15 ENST00000371244.4
PRKAA2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr6_-_75994536 0.15 ENST00000475111.2
ENST00000230461.6
TMEM30A
transmembrane protein 30A
chr12_+_41086297 0.15 ENST00000551295.2
CNTN1
contactin 1
chr14_+_90864504 0.15 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr4_-_76598326 0.15 ENST00000503660.1
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chr11_+_47279248 0.15 ENST00000449369.1
NR1H3
nuclear receptor subfamily 1, group H, member 3
chr13_-_95953589 0.15 ENST00000538287.1
ENST00000376887.4
ENST00000412704.1
ENST00000536256.1
ENST00000431522.1
ABCC4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr11_-_117695449 0.15 ENST00000292079.2
FXYD2
FXYD domain containing ion transport regulator 2
chr2_+_33701684 0.15 ENST00000442390.1
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_-_37488834 0.14 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr12_-_121972556 0.14 ENST00000545022.1
KDM2B
lysine (K)-specific demethylase 2B
chr17_+_9548845 0.14 ENST00000570475.1
ENST00000285199.7
USP43
ubiquitin specific peptidase 43
chr12_+_122459757 0.14 ENST00000261822.4
BCL7A
B-cell CLL/lymphoma 7A
chr10_+_70748487 0.14 ENST00000361983.4
KIAA1279
KIAA1279
chr4_+_6202448 0.14 ENST00000508601.1
RP11-586D19.1
RP11-586D19.1
chr1_+_18807424 0.14 ENST00000400664.1
KLHDC7A
kelch domain containing 7A
chr4_+_169418195 0.14 ENST00000261509.6
ENST00000335742.7
PALLD
palladin, cytoskeletal associated protein
chr1_+_109792641 0.14 ENST00000271332.3
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2
chr1_-_169555779 0.14 ENST00000367797.3
ENST00000367796.3
F5
coagulation factor V (proaccelerin, labile factor)
chr3_-_50383096 0.14 ENST00000442887.1
ENST00000360165.3
ZMYND10
zinc finger, MYND-type containing 10
chr1_-_220219775 0.14 ENST00000609181.1
EPRS
glutamyl-prolyl-tRNA synthetase
chr14_+_56078695 0.14 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr5_+_138089100 0.14 ENST00000520339.1
ENST00000355078.5
ENST00000302763.7
ENST00000518910.1
CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa

Network of associatons between targets according to the STRING database.

First level regulatory network of MESP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.5 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.3 GO:0097195 pilomotor reflex(GO:0097195)
0.1 0.4 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.2 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.4 GO:0015864 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.1 0.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.2 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.1 0.2 GO:0061193 sensory organ boundary specification(GO:0008052) formation of organ boundary(GO:0010160) taste bud development(GO:0061193)
0.1 0.3 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.4 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.1 0.6 GO:0006552 leucine catabolic process(GO:0006552)
0.1 0.2 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.2 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.2 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.6 GO:0021678 third ventricle development(GO:0021678)
0.0 0.2 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.0 0.1 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.2 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.4 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.0 0.1 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.0 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0046882 negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.1 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:1903413 cellular response to bile acid(GO:1903413)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0003168 Purkinje myocyte differentiation(GO:0003168) cardiac pacemaker cell fate commitment(GO:0060927) atrioventricular node cell fate commitment(GO:0060929)
0.0 1.0 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.4 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.2 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0003165 Purkinje myocyte development(GO:0003165)
0.0 0.1 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.2 GO:0007051 spindle organization(GO:0007051)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.7 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:1904616 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.2 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.0 0.1 GO:2000542 negative regulation of gastrulation(GO:2000542)
0.0 0.2 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.4 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.2 GO:0021903 rostrocaudal neural tube patterning(GO:0021903)
0.0 0.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.3 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.0 GO:0071878 negative regulation of adrenergic receptor signaling pathway(GO:0071878)
0.0 0.1 GO:2001250 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.2 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0010728 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) renal artery morphogenesis(GO:0061441) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.2 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.3 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.1 GO:0008078 mesoderm migration involved in gastrulation(GO:0007509) mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.2 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.1 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.1 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.0 0.1 GO:1903382 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
0.0 0.1 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.4 GO:0021756 striatum development(GO:0021756)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.3 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0032826 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.2 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.0 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.1 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.0 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.0 0.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.0 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.0 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.0 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.4 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.2 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.2 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.0 0.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.6 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.0 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.3 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.0 0.1 GO:0009439 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.0 0.2 GO:0016322 neuron remodeling(GO:0016322)
0.0 0.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086) regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.0 GO:1903572 coronary vein morphogenesis(GO:0003169) cardiac vascular smooth muscle cell development(GO:0060948) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.0 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.2 GO:0015871 choline transport(GO:0015871)
0.0 0.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.3 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:1903012 positive regulation of bone development(GO:1903012)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.1 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:1903433 regulation of constitutive secretory pathway(GO:1903433)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 0.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 0.3 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 0.2 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.3 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.0 0.3 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.3 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.3 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:1990425 ryanodine receptor complex(GO:1990425)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.1 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.0 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.6 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1 0.3 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.2 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.3 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.2 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.2 GO:0016250 N-sulfoglucosamine sulfohydrolase activity(GO:0016250) hydrolase activity, acting on acid sulfur-nitrogen bonds(GO:0016826)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.4 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.4 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.0 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.0 0.2 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.1 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368) oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901) sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.2 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.1 GO:0048763 HLH domain binding(GO:0043398) calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.2 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.1 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.0 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.0 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.1 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0052844 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.2 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.0 GO:0001515 opioid peptide activity(GO:0001515)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.6 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels