Project
A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for MEIS1
Z-value: 1.22
Motif logo
Transcription factors associated with MEIS1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| MEIS1 | hg19_v2_chr2_+_66662249_66662267 | 0.99 | 1.2e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_+_150866779 Show fit | 1.69 |
ENST00000370353.3
|
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane) |
|
| chr17_+_68165657 Show fit | 1.44 |
ENST00000243457.3
|
potassium inwardly-rectifying channel, subfamily J, member 2 |
|
| chr6_+_53794780 Show fit | 1.15 |
ENST00000505762.1
ENST00000511369.1 ENST00000431554.2 |
muscular LMNA-interacting protein RP11-411K7.1 |
|
| chr12_-_57030096 Show fit | 0.92 |
ENST00000549506.1
|
bromodomain adjacent to zinc finger domain, 2A |
|
| chr2_-_118943930 Show fit | 0.64 |
ENST00000449075.1
ENST00000414886.1 ENST00000449819.1 |
AC093901.1 |
|
| chr5_+_49962772 Show fit | 0.62 |
ENST00000281631.5
ENST00000513738.1 ENST00000503665.1 ENST00000514067.2 ENST00000503046.1 |
poly (ADP-ribose) polymerase family, member 8 |
|
| chr1_-_144866711 Show fit | 0.60 |
ENST00000530130.1
|
phosphodiesterase 4D interacting protein |
|
| chr12_+_19358192 Show fit | 0.58 |
ENST00000538305.1
|
pleckstrin homology domain containing, family A member 5 |
|
| chr17_-_39341594 Show fit | 0.57 |
ENST00000398472.1
|
keratin associated protein 4-1 |
|
| chr5_-_138780159 Show fit | 0.57 |
ENST00000512473.1
ENST00000515581.1 ENST00000515277.1 |
DnaJ (Hsp40) homolog, subfamily C, member 18 |
Network of associatons between targets according to the STRING database.
First level regulatory network of MEIS1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 1.4 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
| 0.1 | 1.1 | GO:1903800 | positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.0 | 1.0 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.0 | 0.9 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.1 | 0.8 | GO:0021840 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129) |
| 0.1 | 0.7 | GO:0045591 | positive regulation of regulatory T cell differentiation(GO:0045591) |
| 0.1 | 0.7 | GO:1990416 | cellular response to brain-derived neurotrophic factor stimulus(GO:1990416) |
| 0.1 | 0.6 | GO:0044334 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
| 0.1 | 0.5 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.1 | 0.5 | GO:0006203 | dGTP catabolic process(GO:0006203) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.9 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 0.7 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 0.6 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.0 | 0.6 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 0.5 | GO:0033269 | internode region of axon(GO:0033269) |
| 0.1 | 0.4 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.0 | 0.4 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.0 | 0.4 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.0 | 0.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | GO:0086008 | voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008) |
| 0.0 | 1.4 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 0.9 | GO:0001163 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.0 | 0.9 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 0.8 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.1 | 0.8 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.2 | 0.7 | GO:0004676 | 3-phosphoinositide-dependent protein kinase activity(GO:0004676) |
| 0.0 | 0.7 | GO:0010314 | phosphatidylinositol-5-phosphate binding(GO:0010314) |
| 0.0 | 0.7 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 0.6 | GO:0032554 | purine deoxyribonucleotide binding(GO:0032554) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.7 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.2 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
| 0.1 | 0.1 | PID S1P S1P3 PATHWAY | S1P3 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.8 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.6 | REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA | Genes involved in G beta:gamma signalling through PI3Kgamma |
| 0.0 | 0.6 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.0 | 0.4 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.0 | 0.4 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.3 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.2 | REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION | Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation |
| 0.0 | 0.2 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.0 | 0.1 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |