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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for LHX8

Z-value: 1.61

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Transcription factors associated with LHX8

Gene Symbol Gene ID Gene Info
LHX8
ENSG00000162624.10 LIM homeobox 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX8hg19_v2_chr1_+_75594119_755941190.928.3e-02Click!

Activity profile of LHX8 motif

Sorted Z-values of LHX8 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_57229155 2.06 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr10_-_101825151 1.92 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr4_+_174089904 1.68 ENST00000265000.4
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr6_+_26087509 1.50 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
HFE
hemochromatosis
chr2_-_152118276 1.39 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr14_+_57046500 1.26 ENST00000261556.6
TMEM260
transmembrane protein 260
chr7_+_30589829 1.22 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr1_-_247242048 1.20 ENST00000366503.2
ZNF670
zinc finger protein 670
chr19_-_58204128 1.11 ENST00000597520.1
AC004017.1
Uncharacterized protein
chr4_+_155484103 1.08 ENST00000302068.4
FGB
fibrinogen beta chain
chr4_-_110723335 1.07 ENST00000394634.2
CFI
complement factor I
chr4_+_174089951 1.06 ENST00000512285.1
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_-_149459549 1.03 ENST00000369175.3
FAM72C
family with sequence similarity 72, member C
chr4_+_155484155 1.00 ENST00000509493.1
FGB
fibrinogen beta chain
chr12_-_54982420 0.98 ENST00000257905.8
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr12_-_71551868 0.94 ENST00000247829.3
TSPAN8
tetraspanin 8
chr6_+_26087646 0.94 ENST00000309234.6
HFE
hemochromatosis
chr12_-_71551652 0.93 ENST00000546561.1
TSPAN8
tetraspanin 8
chr12_-_39734783 0.91 ENST00000552961.1
KIF21A
kinesin family member 21A
chr18_-_14132422 0.88 ENST00000589498.1
ENST00000590202.1
ZNF519
zinc finger protein 519
chr12_+_64173583 0.86 ENST00000261234.6
TMEM5
transmembrane protein 5
chr8_+_17354617 0.85 ENST00000470360.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr4_-_110723194 0.84 ENST00000394635.3
CFI
complement factor I
chr14_+_57046530 0.83 ENST00000536419.1
ENST00000538838.1
TMEM260
transmembrane protein 260
chr18_+_71815743 0.82 ENST00000169551.6
ENST00000580087.1
TIMM21
translocase of inner mitochondrial membrane 21 homolog (yeast)
chr4_-_110723134 0.82 ENST00000510800.1
ENST00000512148.1
CFI
complement factor I
chr8_+_17354587 0.72 ENST00000494857.1
ENST00000522656.1
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr2_-_14541060 0.72 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr10_-_70231639 0.71 ENST00000551118.2
ENST00000358410.3
ENST00000399180.2
ENST00000399179.2
DNA2
DNA replication helicase/nuclease 2
chr11_+_72975578 0.71 ENST00000393592.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_+_72975524 0.70 ENST00000540342.1
ENST00000542092.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr13_+_98605902 0.70 ENST00000460070.1
ENST00000481455.1
ENST00000261574.5
ENST00000493281.1
ENST00000463157.1
ENST00000471898.1
ENST00000489058.1
ENST00000481689.1
IPO5
importin 5
chr10_+_94352956 0.70 ENST00000260731.3
KIF11
kinesin family member 11
chr19_-_10697895 0.66 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr2_+_108145913 0.65 ENST00000443205.1
AC096669.3
AC096669.3
chr12_-_88974236 0.63 ENST00000228280.5
ENST00000552044.1
ENST00000357116.4
KITLG
KIT ligand
chr7_-_140482926 0.62 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr6_+_43543942 0.61 ENST00000372226.1
ENST00000443535.1
POLH
polymerase (DNA directed), eta
chr15_-_65426174 0.59 ENST00000204549.4
PDCD7
programmed cell death 7
chr8_+_9009296 0.59 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr14_-_92247032 0.58 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
CATSPERB
catsper channel auxiliary subunit beta
chr7_+_74188309 0.57 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr1_+_70876926 0.55 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr11_+_1049862 0.55 ENST00000534584.1
RP13-870H17.3
RP13-870H17.3
chr3_-_187455680 0.53 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr16_-_53737722 0.52 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr11_+_72975559 0.51 ENST00000349767.2
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr8_+_101349823 0.51 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr12_+_9822331 0.50 ENST00000545918.1
ENST00000543300.1
ENST00000261339.6
ENST00000466035.2
CLEC2D
C-type lectin domain family 2, member D
chr13_+_96085847 0.49 ENST00000376873.3
CLDN10
claudin 10
chr2_+_190541153 0.49 ENST00000313581.4
ENST00000438402.2
ENST00000431575.2
ENST00000281412.6
ANKAR
ankyrin and armadillo repeat containing
chr22_+_23487513 0.49 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr6_+_76599809 0.48 ENST00000430435.1
MYO6
myosin VI
chr5_+_41904431 0.47 ENST00000381647.2
C5orf51
chromosome 5 open reading frame 51
chr10_-_110321541 0.47 ENST00000366253.2
RP11-163F15.1
RP11-163F15.1
chr3_-_151176497 0.46 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chrX_+_108779870 0.46 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr6_-_56507586 0.45 ENST00000439203.1
ENST00000518935.1
ENST00000446842.2
ENST00000370765.6
ENST00000244364.6
DST
dystonin
chr21_-_16254231 0.44 ENST00000412426.1
ENST00000418954.1
AF127936.7
AF127936.7
chr9_+_26956371 0.44 ENST00000380062.5
ENST00000518614.1
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chrX_+_108779004 0.43 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr17_+_48823975 0.43 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr2_+_102758271 0.42 ENST00000428279.1
IL1R1
interleukin 1 receptor, type I
chr15_-_40074996 0.42 ENST00000350221.3
FSIP1
fibrous sheath interacting protein 1
chr1_+_95616933 0.42 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr3_+_127317945 0.41 ENST00000472731.1
MCM2
minichromosome maintenance complex component 2
chr4_-_100242549 0.40 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr16_+_22217577 0.39 ENST00000263026.5
EEF2K
eukaryotic elongation factor-2 kinase
chr9_+_26956474 0.38 ENST00000429045.2
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr7_+_151791095 0.38 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr7_+_115862858 0.37 ENST00000393481.2
TES
testis derived transcript (3 LIM domains)
chr8_+_75262612 0.37 ENST00000220822.7
GDAP1
ganglioside induced differentiation associated protein 1
chr12_-_92536433 0.37 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr19_-_4535233 0.37 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
PLIN5
perilipin 5
chr7_+_12727250 0.36 ENST00000404894.1
ARL4A
ADP-ribosylation factor-like 4A
chr9_-_36276966 0.36 ENST00000543356.2
ENST00000396594.3
GNE
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr8_+_22424551 0.36 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr11_-_31531121 0.36 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr11_+_59480899 0.35 ENST00000300150.7
STX3
syntaxin 3
chr11_-_118122996 0.35 ENST00000525386.1
ENST00000527472.1
ENST00000278949.4
MPZL3
myelin protein zero-like 3
chr4_+_166300084 0.35 ENST00000402744.4
CPE
carboxypeptidase E
chr4_-_164534657 0.35 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr2_+_158114051 0.34 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr12_-_8088773 0.34 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr2_+_128377550 0.34 ENST00000437387.1
ENST00000409090.1
MYO7B
myosin VIIB
chr22_-_29107919 0.33 ENST00000434810.1
ENST00000456369.1
CHEK2
checkpoint kinase 2
chr8_+_99076509 0.33 ENST00000318528.3
C8orf47
chromosome 8 open reading frame 47
chr7_+_55980331 0.33 ENST00000429591.2
ZNF713
zinc finger protein 713
chr2_-_136678123 0.32 ENST00000422708.1
DARS
aspartyl-tRNA synthetase
chr12_+_14572070 0.32 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
ATF7IP
activating transcription factor 7 interacting protein
chr4_-_186125077 0.31 ENST00000458385.2
ENST00000514798.1
ENST00000296775.6
KIAA1430
KIAA1430
chr15_+_65843130 0.31 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr2_-_136288113 0.30 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr2_-_152118352 0.29 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr1_+_109419804 0.29 ENST00000435475.1
GPSM2
G-protein signaling modulator 2
chr15_+_78832747 0.29 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr22_+_20703829 0.28 ENST00000583722.1
FAM230A
family with sequence similarity 230, member A
chr12_+_48516463 0.27 ENST00000546465.1
PFKM
phosphofructokinase, muscle
chr1_+_145883868 0.27 ENST00000447947.2
GPR89C
G protein-coupled receptor 89C
chr16_-_53737795 0.26 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr17_-_38821373 0.25 ENST00000394052.3
KRT222
keratin 222
chr5_-_75008244 0.25 ENST00000510798.1
ENST00000446329.2
POC5
POC5 centriolar protein
chr9_-_5833027 0.25 ENST00000339450.5
ERMP1
endoplasmic reticulum metallopeptidase 1
chr11_-_68780824 0.25 ENST00000441623.1
ENST00000309099.6
MRGPRF
MAS-related GPR, member F
chr2_-_152830479 0.23 ENST00000360283.6
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr12_+_94071341 0.23 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr12_+_97306295 0.23 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr13_+_53216565 0.23 ENST00000357495.2
HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr8_-_82608409 0.22 ENST00000518568.1
SLC10A5
solute carrier family 10, member 5
chr3_-_52804872 0.22 ENST00000535191.1
ENST00000461689.1
ENST00000383721.4
ENST00000233027.5
NEK4
NIMA-related kinase 4
chr2_-_145275109 0.22 ENST00000431672.2
ZEB2
zinc finger E-box binding homeobox 2
chr8_-_141810634 0.21 ENST00000521986.1
ENST00000523539.1
ENST00000538769.1
PTK2
protein tyrosine kinase 2
chr1_-_160492994 0.21 ENST00000368055.1
ENST00000368057.3
ENST00000368059.3
SLAMF6
SLAM family member 6
chr1_-_212004090 0.21 ENST00000366997.4
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr9_-_179018 0.20 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
CBWD1
COBW domain containing 1
chr13_+_38923959 0.20 ENST00000379649.1
ENST00000239878.4
ENST00000437952.1
ENST00000379641.1
UFM1
ubiquitin-fold modifier 1
chr6_+_26251835 0.19 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr5_+_140165876 0.19 ENST00000504120.2
ENST00000394633.3
ENST00000378133.3
PCDHA1
protocadherin alpha 1
chr2_-_178128250 0.19 ENST00000448782.1
ENST00000446151.2
NFE2L2
nuclear factor, erythroid 2-like 2
chr6_-_64029879 0.19 ENST00000370658.5
ENST00000485906.2
ENST00000370657.4
LGSN
lengsin, lens protein with glutamine synthetase domain
chr16_-_88770019 0.19 ENST00000541206.2
RNF166
ring finger protein 166
chr3_+_195447738 0.19 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
MUC20
mucin 20, cell surface associated
chr12_+_48592134 0.18 ENST00000595310.1
DKFZP779L1853
DKFZP779L1853
chr2_+_216946589 0.18 ENST00000433112.1
ENST00000454545.1
ENST00000437356.2
ENST00000295658.4
ENST00000455479.1
ENST00000406027.2
TMEM169
transmembrane protein 169
chr2_-_37068530 0.18 ENST00000593798.1
AC007382.1
Uncharacterized protein
chr11_+_6226782 0.18 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr16_+_67927147 0.18 ENST00000291041.5
PSKH1
protein serine kinase H1
chr12_-_53893399 0.18 ENST00000267079.2
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chrX_+_102883620 0.17 ENST00000372626.3
TCEAL1
transcription elongation factor A (SII)-like 1
chr1_+_202789394 0.17 ENST00000330493.5
RP11-480I12.4
Putative inactive alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein LOC641515
chr4_-_83812248 0.17 ENST00000514326.1
ENST00000505434.1
ENST00000503058.1
ENST00000348405.4
ENST00000505984.1
ENST00000513858.1
ENST00000508479.1
ENST00000443462.2
ENST00000508502.1
ENST00000509142.1
ENST00000432794.1
ENST00000448323.1
ENST00000326950.5
ENST00000311785.7
SEC31A
SEC31 homolog A (S. cerevisiae)
chr2_-_145275828 0.17 ENST00000392861.2
ENST00000409211.1
ZEB2
zinc finger E-box binding homeobox 2
chr22_+_23054174 0.16 ENST00000390308.2
IGLV3-21
immunoglobulin lambda variable 3-21
chr11_-_3400442 0.15 ENST00000429541.2
ENST00000532539.1
ZNF195
zinc finger protein 195
chr14_+_62164340 0.15 ENST00000557538.1
ENST00000539097.1
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr2_-_178128528 0.14 ENST00000397063.4
ENST00000421929.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr3_-_119182523 0.14 ENST00000319172.5
TMEM39A
transmembrane protein 39A
chr20_-_30458491 0.14 ENST00000339738.5
DUSP15
dual specificity phosphatase 15
chr8_-_112039643 0.14 ENST00000524283.1
RP11-946L20.2
RP11-946L20.2
chr4_-_83812402 0.14 ENST00000395310.2
SEC31A
SEC31 homolog A (S. cerevisiae)
chr7_+_7811992 0.13 ENST00000406829.1
RPA3-AS1
RPA3 antisense RNA 1
chr4_-_109684120 0.13 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL
ethanolamine-phosphate phospho-lyase
chr3_-_57199397 0.13 ENST00000296318.7
IL17RD
interleukin 17 receptor D
chr5_+_135170331 0.13 ENST00000425402.1
ENST00000274513.5
ENST00000420621.1
ENST00000433282.2
ENST00000412661.2
SLC25A48
solute carrier family 25, member 48
chr19_+_21264980 0.13 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr2_+_234621551 0.12 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr1_+_47603109 0.12 ENST00000371890.3
ENST00000294337.3
ENST00000371891.3
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 22
chrX_+_70798261 0.12 ENST00000373696.3
ACRC
acidic repeat containing
chr4_+_22999152 0.12 ENST00000511453.1
RP11-412P11.1
RP11-412P11.1
chr16_-_11922665 0.11 ENST00000573319.1
ENST00000577041.1
ENST00000574028.1
ENST00000571259.1
ENST00000573037.1
ENST00000571158.1
BCAR4
breast cancer anti-estrogen resistance 4 (non-protein coding)
chr7_-_14026123 0.11 ENST00000420159.2
ENST00000399357.3
ENST00000403527.1
ETV1
ets variant 1
chr11_-_66964638 0.11 ENST00000444002.2
AP001885.1
AP001885.1
chr16_-_2314222 0.11 ENST00000566397.1
RNPS1
RNA binding protein S1, serine-rich domain
chr6_-_128222103 0.11 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS
thymocyte selection associated
chrX_-_20236970 0.11 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr12_+_45686457 0.10 ENST00000441606.2
ANO6
anoctamin 6
chr2_+_171640291 0.10 ENST00000409885.1
ERICH2
glutamate-rich 2
chr2_-_152830441 0.09 ENST00000534999.1
ENST00000397327.2
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr11_+_29181503 0.09 ENST00000530960.1
RP11-466I1.1
RP11-466I1.1
chrX_+_73164167 0.09 ENST00000414209.1
ENST00000602895.1
ENST00000453317.1
ENST00000602546.1
ENST00000602985.1
ENST00000415215.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr12_+_54410664 0.09 ENST00000303406.4
HOXC4
homeobox C4
chr22_+_29876197 0.08 ENST00000310624.6
NEFH
neurofilament, heavy polypeptide
chr12_-_8088871 0.08 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr19_+_42300548 0.08 ENST00000344550.4
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr18_-_11908272 0.07 ENST00000592977.1
ENST00000590501.1
ENST00000586844.1
MPPE1
metallophosphoesterase 1
chr10_+_127585118 0.07 ENST00000449042.2
FANK1
fibronectin type III and ankyrin repeat domains 1
chrX_+_73164149 0.07 ENST00000602938.1
ENST00000602294.1
ENST00000602920.1
ENST00000602737.1
ENST00000602772.1
JPX
JPX transcript, XIST activator (non-protein coding)
chr2_-_183291741 0.06 ENST00000351439.5
ENST00000409365.1
PDE1A
phosphodiesterase 1A, calmodulin-dependent
chr9_+_70856899 0.06 ENST00000377342.5
ENST00000478048.1
CBWD3
COBW domain containing 3
chr1_+_113009163 0.06 ENST00000256640.5
WNT2B
wingless-type MMTV integration site family, member 2B
chr1_+_165864821 0.06 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr1_-_236445251 0.06 ENST00000354619.5
ENST00000327333.8
ERO1LB
ERO1-like beta (S. cerevisiae)
chr6_+_10633993 0.06 ENST00000417671.1
GCNT6
glucosaminyl (N-acetyl) transferase 6
chr2_-_145275228 0.06 ENST00000427902.1
ENST00000409487.3
ENST00000470879.1
ENST00000435831.1
ZEB2
zinc finger E-box binding homeobox 2
chr19_+_34856078 0.06 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
GPI
glucose-6-phosphate isomerase
chr19_-_695427 0.06 ENST00000329267.7
PRSS57
protease, serine, 57
chr5_+_157158205 0.05 ENST00000231198.7
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr8_+_39806685 0.05 ENST00000389060.4
IDO2
indoleamine 2,3-dioxygenase 2
chr21_-_34863998 0.05 ENST00000402202.1
ENST00000381947.3
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr4_-_153332886 0.05 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr22_-_29457832 0.04 ENST00000216071.4
C22orf31
chromosome 22 open reading frame 31
chr1_+_240177627 0.04 ENST00000447095.1
FMN2
formin 2
chr10_+_135207598 0.04 ENST00000477902.2
MTG1
mitochondrial ribosome-associated GTPase 1
chr20_+_34824355 0.04 ENST00000397286.3
ENST00000320849.4
ENST00000373932.3
AAR2
AAR2 splicing factor homolog (S. cerevisiae)
chr13_-_24895566 0.04 ENST00000422229.2
AL359736.1
protein PCOTH isoform 1
chr11_-_72504637 0.04 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chrX_+_56258844 0.04 ENST00000374928.3
KLF8
Kruppel-like factor 8
chr10_-_47151341 0.04 ENST00000422732.2
LINC00842
long intergenic non-protein coding RNA 842
chr1_+_119957554 0.04 ENST00000543831.1
ENST00000433745.1
ENST00000369416.3
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr1_-_48937838 0.04 ENST00000371847.3
SPATA6
spermatogenesis associated 6
chr1_+_224301787 0.03 ENST00000366862.5
ENST00000424254.2
FBXO28
F-box protein 28
chr2_-_178128199 0.03 ENST00000449627.1
NFE2L2
nuclear factor, erythroid 2-like 2
chr12_-_10766184 0.03 ENST00000539554.1
ENST00000381881.2
ENST00000320756.2
MAGOHB
mago-nashi homolog B (Drosophila)
chr4_+_76439095 0.03 ENST00000506261.1
THAP6
THAP domain containing 6
chr7_-_28220354 0.03 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr7_-_14880892 0.03 ENST00000406247.3
ENST00000399322.3
ENST00000258767.5
DGKB
diacylglycerol kinase, beta 90kDa
chr9_-_139372141 0.03 ENST00000313050.7
SEC16A
SEC16 homolog A (S. cerevisiae)
chr12_+_26205496 0.03 ENST00000537946.1
ENST00000541218.1
ENST00000282884.9
ENST00000545413.1
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr15_-_75918787 0.03 ENST00000564086.1
SNUPN
snurportin 1
chr2_+_200775971 0.02 ENST00000319974.5
C2orf69
chromosome 2 open reading frame 69

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.8 2.3 GO:0030070 insulin processing(GO:0030070)
0.5 1.6 GO:0034226 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.3 0.9 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 0.6 GO:0033025 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.2 0.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.2 0.9 GO:1903464 negative regulation of mitotic cell cycle DNA replication(GO:1903464)
0.2 2.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.4 GO:0034059 response to anoxia(GO:0034059)
0.1 1.9 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.6 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.3 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.3 GO:0036292 DNA rewinding(GO:0036292)
0.1 0.4 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.1 0.6 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.4 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.1 0.3 GO:0031291 Ran protein signal transduction(GO:0031291)
0.1 0.9 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.2 GO:0070101 positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.0 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.3 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
0.0 0.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.3 GO:1904970 brush border assembly(GO:1904970)
0.0 0.8 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.4 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 3.4 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.7 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334) positive regulation of cell adhesion mediated by integrin(GO:0033630)
0.0 0.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.8 GO:0043584 lateral ventricle development(GO:0021670) nose development(GO:0043584)
0.0 0.1 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.0 0.2 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 2.8 GO:2000257 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 0.1 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.6 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.2 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.1 GO:0000066 mitochondrial ornithine transport(GO:0000066) ornithine transport(GO:0015822)
0.0 0.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0051758 homologous chromosome movement towards spindle pole involved in homologous chromosome segregation(GO:0051758)
0.0 0.2 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 1.8 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.2 GO:0001787 natural killer cell proliferation(GO:0001787)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.4 GO:1990357 terminal web(GO:1990357)
0.2 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.1 2.1 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 2.1 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 0.6 GO:0032010 phagolysosome(GO:0032010)
0.1 0.8 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.7 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.6 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0005287 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.3 2.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 0.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.2 1.9 GO:0071553 uridine nucleotide receptor activity(GO:0015065) UDP-activated nucleotide receptor activity(GO:0045029) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.2 0.5 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.7 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 2.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.1 3.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.4 GO:0035473 lipase binding(GO:0035473)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.4 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.1 0.3 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.5 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 2.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.3 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.8 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 2.0 GO:0051087 chaperone binding(GO:0051087)
0.0 0.7 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.1 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 2.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 3.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.7 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 2.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes