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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
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Results for LHX3
Z-value: 1.36
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Transcription factors associated with LHX3
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| LHX3 | hg19_v2_chr9_-_139096955_139096979 | 0.72 | 2.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_124741451 Show fit | 2.00 |
ENST00000520519.1
|
annexin A13 |
|
| chr4_+_155484103 Show fit | 1.53 |
ENST00000302068.4
|
fibrinogen beta chain |
|
| chr6_-_47445214 Show fit | 1.48 |
ENST00000604014.1
|
RP11-385F7.1 |
|
| chr4_+_113568207 Show fit | 1.40 |
ENST00000511529.1
|
La ribonucleoprotein domain family, member 7 |
|
| chr4_+_155484155 Show fit | 1.38 |
ENST00000509493.1
|
fibrinogen beta chain |
|
| chr17_-_4938712 Show fit | 1.25 |
ENST00000254853.5
ENST00000424747.1 |
solute carrier family 52 (riboflavin transporter), member 1 |
|
| chr17_-_64225508 Show fit | 1.03 |
ENST00000205948.6
|
apolipoprotein H (beta-2-glycoprotein I) |
|
| chr6_+_26104104 Show fit | 0.97 |
ENST00000377803.2
|
histone cluster 1, H4c |
|
| chr19_-_49149553 Show fit | 0.89 |
ENST00000084798.4
|
carbonic anhydrase XI |
|
| chr12_+_49740700 Show fit | 0.79 |
ENST00000549441.2
ENST00000395069.3 |
DnaJ (Hsp40) homolog, subfamily C, member 22 |
Network of associatons between targets according to the STRING database.
First level regulatory network of LHX3
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.9 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 0.0 | 2.1 | GO:0043486 | histone exchange(GO:0043486) |
| 0.5 | 1.4 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 0.2 | 1.2 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.0 | 1.2 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 1.0 | GO:0034197 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
| 0.0 | 0.9 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 0.8 | GO:0030950 | establishment or maintenance of actin cytoskeleton polarity(GO:0030950) |
| 0.1 | 0.7 | GO:0071279 | cellular response to cobalt ion(GO:0071279) |
| 0.1 | 0.6 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.9 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 2.1 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 1.0 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.0 | 0.8 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.0 | 0.7 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 0.4 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.2 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.0 | 0.2 | GO:0005742 | mitochondrial outer membrane translocase complex(GO:0005742) |
| 0.0 | 0.2 | GO:0032437 | cuticular plate(GO:0032437) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | GO:0051087 | chaperone binding(GO:0051087) |
| 0.0 | 2.1 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.0 | 2.0 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.0 | 1.6 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.3 | 1.4 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.0 | 1.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 1.2 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.3 | 1.0 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.1 | 0.9 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.1 | 0.9 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.2 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.8 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.0 | 0.4 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 0.4 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.9 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 1.0 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.9 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.0 | 0.7 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.0 | 0.6 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.5 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 0.4 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.0 | 0.4 | REACTOME SIGNALLING TO P38 VIA RIT AND RIN | Genes involved in Signalling to p38 via RIT and RIN |
| 0.0 | 0.3 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.0 | 0.2 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |