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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for LHX3

Z-value: 1.36

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Transcription factors associated with LHX3

Gene Symbol Gene ID Gene Info
LHX3
ENSG00000107187.11 LIM homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
LHX3hg19_v2_chr9_-_139096955_1390969790.722.8e-01Click!

Activity profile of LHX3 motif

Sorted Z-values of LHX3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_124741451 2.00 ENST00000520519.1
ANXA13
annexin A13
chr4_+_155484103 1.53 ENST00000302068.4
FGB
fibrinogen beta chain
chr6_-_47445214 1.48 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chr4_+_113568207 1.40 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr4_+_155484155 1.38 ENST00000509493.1
FGB
fibrinogen beta chain
chr17_-_4938712 1.25 ENST00000254853.5
ENST00000424747.1
SLC52A1
solute carrier family 52 (riboflavin transporter), member 1
chr17_-_64225508 1.03 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_+_26104104 0.97 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr19_-_49149553 0.89 ENST00000084798.4
CA11
carbonic anhydrase XI
chr12_+_49740700 0.79 ENST00000549441.2
ENST00000395069.3
DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr12_-_118628350 0.78 ENST00000537952.1
ENST00000537822.1
TAOK3
TAO kinase 3
chr19_+_50016411 0.77 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr9_-_128246769 0.75 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr19_-_51920952 0.72 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
SIGLEC10
sialic acid binding Ig-like lectin 10
chr17_+_1674982 0.71 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_+_696000 0.71 ENST00000381489.5
PRR26
proline rich 26
chr1_-_150208320 0.70 ENST00000534220.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr10_+_695888 0.63 ENST00000441152.2
PRR26
proline rich 26
chr18_+_61616510 0.62 ENST00000408945.3
HMSD
histocompatibility (minor) serpin domain containing
chr17_+_68071389 0.62 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr19_+_50016610 0.62 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr22_+_23487513 0.61 ENST00000263116.2
ENST00000341989.4
RAB36
RAB36, member RAS oncogene family
chr9_-_75567962 0.59 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr14_-_21566731 0.58 ENST00000360947.3
ZNF219
zinc finger protein 219
chr3_+_151591422 0.55 ENST00000362032.5
SUCNR1
succinate receptor 1
chr15_-_81195510 0.52 ENST00000561295.1
RP11-351M8.1
Uncharacterized protein
chr11_+_327171 0.50 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr17_-_27418537 0.49 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr7_+_134671234 0.48 ENST00000436302.2
ENST00000359383.3
ENST00000458078.1
ENST00000435976.2
ENST00000455283.2
AGBL3
ATP/GTP binding protein-like 3
chr1_-_150208291 0.48 ENST00000533654.1
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_150208412 0.47 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr12_-_118628315 0.44 ENST00000540561.1
TAOK3
TAO kinase 3
chr7_-_140482926 0.44 ENST00000496384.2
BRAF
v-raf murine sarcoma viral oncogene homolog B
chr9_-_215744 0.43 ENST00000382387.2
C9orf66
chromosome 9 open reading frame 66
chr1_-_150208363 0.43 ENST00000436748.2
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr4_-_185275104 0.42 ENST00000317596.3
RP11-290F5.2
RP11-290F5.2
chr8_-_25281747 0.41 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr7_-_105332084 0.41 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr1_+_81771806 0.39 ENST00000370721.1
ENST00000370727.1
ENST00000370725.1
ENST00000370723.1
ENST00000370728.1
ENST00000370730.1
LPHN2
latrophilin 2
chr15_-_75748143 0.38 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A
SIN3 transcription regulator family member A
chr3_+_141106643 0.37 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr4_+_3344141 0.37 ENST00000306648.7
RGS12
regulator of G-protein signaling 12
chr19_-_6279932 0.36 ENST00000252674.7
MLLT1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr16_-_28634874 0.34 ENST00000395609.1
ENST00000350842.4
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr7_+_30185406 0.34 ENST00000324489.5
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr14_-_21567009 0.34 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219
zinc finger protein 219
chr10_+_104263743 0.33 ENST00000369902.3
ENST00000369899.2
ENST00000423559.2
SUFU
suppressor of fused homolog (Drosophila)
chr17_-_8263538 0.32 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chrX_+_108779004 0.30 ENST00000218004.1
NXT2
nuclear transport factor 2-like export factor 2
chr11_-_559377 0.30 ENST00000486629.1
C11orf35
chromosome 11 open reading frame 35
chr4_-_23891693 0.30 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_67980744 0.29 ENST00000401547.2
ENST00000453170.1
ENST00000304363.4
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr4_+_95128748 0.29 ENST00000359052.4
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr17_+_35851570 0.28 ENST00000394386.1
DUSP14
dual specificity phosphatase 14
chr19_+_49199209 0.28 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr14_-_45252031 0.27 ENST00000556405.1
RP11-398E10.1
RP11-398E10.1
chr17_+_68071458 0.27 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_-_160549235 0.26 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84
CD84 molecule
chr15_+_65843130 0.26 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr16_-_28937027 0.25 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr1_+_66820058 0.25 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_-_14541060 0.25 ENST00000418420.1
ENST00000417751.1
LINC00276
long intergenic non-protein coding RNA 276
chr14_+_55494323 0.24 ENST00000339298.2
SOCS4
suppressor of cytokine signaling 4
chr12_-_53994805 0.24 ENST00000328463.7
ATF7
activating transcription factor 7
chrX_+_9431324 0.23 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr9_+_125133315 0.23 ENST00000223423.4
ENST00000362012.2
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr14_+_21566980 0.23 ENST00000418511.2
ENST00000554329.2
TMEM253
transmembrane protein 253
chr3_+_101443476 0.23 ENST00000327230.4
ENST00000494050.1
CEP97
centrosomal protein 97kDa
chr7_-_22862406 0.22 ENST00000372879.4
TOMM7
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr12_-_11287243 0.22 ENST00000539585.1
TAS2R30
taste receptor, type 2, member 30
chr17_-_28661065 0.22 ENST00000328886.4
ENST00000538566.2
TMIGD1
transmembrane and immunoglobulin domain containing 1
chr14_-_57197224 0.21 ENST00000554597.1
ENST00000556696.1
RP11-1085N6.3
Uncharacterized protein
chr20_+_5987890 0.21 ENST00000378868.4
CRLS1
cardiolipin synthase 1
chr3_+_148415571 0.21 ENST00000497524.1
ENST00000349243.3
ENST00000542281.1
ENST00000418473.2
ENST00000404754.2
AGTR1
angiotensin II receptor, type 1
chrX_+_24167746 0.19 ENST00000428571.1
ENST00000539115.1
ZFX
zinc finger protein, X-linked
chr11_-_67981046 0.19 ENST00000402789.1
ENST00000402185.2
ENST00000458496.1
SUV420H1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr4_+_41937131 0.19 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr6_+_114178512 0.18 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr15_+_75970672 0.18 ENST00000435356.1
AC105020.1
Uncharacterized protein; cDNA FLJ12988 fis, clone NT2RP3000080
chr19_+_11457232 0.18 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr5_+_81601166 0.17 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr2_+_54785485 0.17 ENST00000333896.5
SPTBN1
spectrin, beta, non-erythrocytic 1
chr3_+_69812877 0.17 ENST00000457080.1
ENST00000328528.6
MITF
microphthalmia-associated transcription factor
chr10_-_115904361 0.17 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr17_-_72772425 0.17 ENST00000578822.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr2_+_135596180 0.16 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr14_+_88852059 0.16 ENST00000045347.7
SPATA7
spermatogenesis associated 7
chr5_-_43557791 0.15 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
PAIP1
poly(A) binding protein interacting protein 1
chr10_-_74283694 0.14 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
MICU1
mitochondrial calcium uptake 1
chr9_+_35042205 0.13 ENST00000312292.5
ENST00000378745.3
C9orf131
chromosome 9 open reading frame 131
chr7_+_30185496 0.13 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr7_+_138915102 0.13 ENST00000486663.1
UBN2
ubinuclein 2
chr3_-_47517302 0.13 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr8_-_30670384 0.12 ENST00000221138.4
ENST00000518243.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr5_-_16916624 0.11 ENST00000513882.1
MYO10
myosin X
chr18_-_21852143 0.11 ENST00000399443.3
OSBPL1A
oxysterol binding protein-like 1A
chr3_-_145940126 0.10 ENST00000498625.1
PLSCR4
phospholipid scramblase 4
chr2_-_188312971 0.09 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL
calcitonin receptor-like
chr2_-_228582709 0.09 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr2_-_99279928 0.09 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr3_-_141719195 0.08 ENST00000397991.4
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr20_-_656823 0.08 ENST00000246104.6
SCRT2
scratch family zinc finger 2
chr7_-_87342564 0.07 ENST00000265724.3
ENST00000416177.1
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr8_-_66750978 0.06 ENST00000523253.1
PDE7A
phosphodiesterase 7A
chr19_+_11457175 0.05 ENST00000458408.1
ENST00000586451.1
ENST00000588592.1
CCDC159
coiled-coil domain containing 159
chrX_+_24167828 0.05 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX
zinc finger protein, X-linked
chr17_-_39623681 0.05 ENST00000225899.3
KRT32
keratin 32
chr4_+_186990298 0.04 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr17_-_72772462 0.04 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr1_-_150944411 0.04 ENST00000368949.4
CERS2
ceramide synthase 2
chr6_+_153019023 0.04 ENST00000367245.5
ENST00000529453.1
MYCT1
myc target 1
chr6_+_130339710 0.03 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3
l(3)mbt-like 3 (Drosophila)
chr19_+_14693888 0.03 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
CLEC17A
C-type lectin domain family 17, member A
chr3_+_186692745 0.02 ENST00000438590.1
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr14_+_55493920 0.02 ENST00000395472.2
ENST00000555846.1
SOCS4
suppressor of cytokine signaling 4
chr16_+_28565230 0.02 ENST00000317058.3
CCDC101
coiled-coil domain containing 101
chr1_+_244214577 0.02 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr7_-_36764142 0.01 ENST00000258749.5
ENST00000535891.1
AOAH
acyloxyacyl hydrolase (neutrophil)
chr18_-_21891460 0.01 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr5_+_55149150 0.00 ENST00000297015.3
IL31RA
interleukin 31 receptor A
chr19_+_48949087 0.00 ENST00000598711.1
GRWD1
glutamate-rich WD repeat containing 1
chr5_-_173217931 0.00 ENST00000522731.1
CTB-43E15.4
CTB-43E15.4

Network of associatons between targets according to the STRING database.

First level regulatory network of LHX3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.2 1.2 GO:0032218 riboflavin transport(GO:0032218)
0.2 2.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1 0.8 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 0.4 GO:1990637 response to prolactin(GO:1990637)
0.1 0.7 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.6 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 0.5 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.1 1.0 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.2 GO:1904640 positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.1 0.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.4 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.3 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.1 0.2 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 2.1 GO:0043486 histone exchange(GO:0043486)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.3 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.1 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.9 GO:0010107 potassium ion import(GO:0010107)
0.0 0.0 GO:0045356 positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.2 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.3 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 2.1 GO:0000812 Swr1 complex(GO:0000812)
0.1 1.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.7 GO:0043203 axon hillock(GO:0043203)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0005770 late endosome(GO:0005770)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.3 1.4 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.9 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0030572 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.1 0.2 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.1 0.6 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.9 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.0 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 1.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 2.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.1 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.8 GO:0070300 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) phosphatidic acid binding(GO:0070300)
0.0 2.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.9 GO:0051087 chaperone binding(GO:0051087)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 1.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.4 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.0 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.7 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules