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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for KLF6

Z-value: 1.58

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Transcription factors associated with KLF6

Gene Symbol Gene ID Gene Info
KLF6
ENSG00000067082.10 Kruppel like factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF6hg19_v2_chr10_-_3827371_3827386-0.919.3e-02Click!

Activity profile of KLF6 motif

Sorted Z-values of KLF6 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_51750948 1.29 ENST00000583046.1
ENST00000398398.2
MBD2
methyl-CpG binding domain protein 2
chr6_+_83073952 1.20 ENST00000543496.1
TPBG
trophoblast glycoprotein
chr11_+_57365150 1.05 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr19_+_10400615 0.99 ENST00000221980.4
ICAM5
intercellular adhesion molecule 5, telencephalin
chr6_+_19837592 0.93 ENST00000378700.3
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr14_-_37051798 0.91 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr20_+_48807351 0.88 ENST00000303004.3
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr19_+_54412517 0.86 ENST00000391767.1
CACNG7
calcium channel, voltage-dependent, gamma subunit 7
chr6_+_32811885 0.82 ENST00000458296.1
ENST00000413039.1
ENST00000429600.1
ENST00000412095.1
ENST00000415067.1
ENST00000395330.1
TAPSAR1
PSMB9
TAP1 and PSMB8 antisense RNA 1
proteasome (prosome, macropain) subunit, beta type, 9
chr17_-_42277203 0.80 ENST00000587097.1
ATXN7L3
ataxin 7-like 3
chr6_+_32811861 0.79 ENST00000453426.1
TAPSAR1
TAP1 and PSMB8 antisense RNA 1
chr10_-_101380121 0.77 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chr4_+_4861385 0.76 ENST00000382723.4
MSX1
msh homeobox 1
chr3_-_88108212 0.65 ENST00000482016.1
CGGBP1
CGG triplet repeat binding protein 1
chr4_-_78740511 0.65 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr10_+_102505468 0.63 ENST00000361791.3
ENST00000355243.3
ENST00000428433.1
ENST00000370296.2
PAX2
paired box 2
chr11_+_48002279 0.62 ENST00000534219.1
ENST00000527952.1
PTPRJ
protein tyrosine phosphatase, receptor type, J
chr6_+_11537910 0.62 ENST00000543875.1
TMEM170B
transmembrane protein 170B
chr15_+_41221536 0.61 ENST00000249749.5
DLL4
delta-like 4 (Drosophila)
chr12_-_7125770 0.60 ENST00000261407.4
LPCAT3
lysophosphatidylcholine acyltransferase 3
chr9_+_100174344 0.60 ENST00000422139.2
TDRD7
tudor domain containing 7
chr5_-_176924562 0.57 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDLIM7
PDZ and LIM domain 7 (enigma)
chr19_+_10196981 0.57 ENST00000591813.1
C19orf66
chromosome 19 open reading frame 66
chr7_-_99774945 0.56 ENST00000292377.2
GPC2
glypican 2
chr6_+_17281573 0.55 ENST00000379052.5
RBM24
RNA binding motif protein 24
chr6_+_99282570 0.53 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr17_+_45771420 0.52 ENST00000578982.1
TBKBP1
TBK1 binding protein 1
chr20_-_31172598 0.52 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr20_+_31350184 0.51 ENST00000328111.2
ENST00000353855.2
ENST00000348286.2
DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr19_+_45504688 0.51 ENST00000221452.8
ENST00000540120.1
ENST00000505236.1
RELB
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr2_+_220299547 0.49 ENST00000312358.7
SPEG
SPEG complex locus
chr20_+_49348109 0.49 ENST00000396039.1
PARD6B
par-6 family cell polarity regulator beta
chr11_+_64053311 0.48 ENST00000540370.1
GPR137
G protein-coupled receptor 137
chr17_+_54671047 0.48 ENST00000332822.4
NOG
noggin
chr11_-_118661588 0.48 ENST00000534980.1
ENST00000526070.2
DDX6
DEAD (Asp-Glu-Ala-Asp) box helicase 6
chr4_+_89444961 0.46 ENST00000513325.1
HERC3
HECT and RLD domain containing E3 ubiquitin protein ligase 3
chr15_-_75743915 0.43 ENST00000394949.4
SIN3A
SIN3 transcription regulator family member A
chr9_-_117267717 0.43 ENST00000374057.3
DFNB31
deafness, autosomal recessive 31
chr2_+_220306745 0.42 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG
SPEG complex locus
chr12_-_54785074 0.42 ENST00000338010.5
ENST00000550774.1
ZNF385A
zinc finger protein 385A
chr17_-_76921459 0.42 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr20_-_56284816 0.41 ENST00000395819.3
ENST00000341744.3
PMEPA1
prostate transmembrane protein, androgen induced 1
chr7_-_100493482 0.40 ENST00000411582.1
ENST00000419336.2
ENST00000241069.5
ENST00000302913.4
ACHE
acetylcholinesterase (Yt blood group)
chr16_+_69599861 0.40 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_-_220408430 0.39 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr18_+_60190226 0.39 ENST00000269499.5
ZCCHC2
zinc finger, CCHC domain containing 2
chr1_-_200992827 0.39 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr12_+_54694979 0.38 ENST00000552848.1
COPZ1
coatomer protein complex, subunit zeta 1
chr6_-_32811771 0.38 ENST00000395339.3
ENST00000374882.3
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8
chr11_-_133826852 0.38 ENST00000533871.2
ENST00000321016.8
IGSF9B
immunoglobulin superfamily, member 9B
chr6_-_31926629 0.38 ENST00000375425.5
ENST00000426722.1
ENST00000441998.1
ENST00000444811.2
ENST00000375429.3
NELFE
negative elongation factor complex member E
chr16_+_3070313 0.37 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr16_+_69599899 0.36 ENST00000567239.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_-_217236750 0.36 ENST00000273067.4
MARCH4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr16_+_30406423 0.36 ENST00000524644.1
ZNF48
zinc finger protein 48
chr19_+_13906250 0.36 ENST00000254323.2
ZSWIM4
zinc finger, SWIM-type containing 4
chr16_+_69600209 0.35 ENST00000566899.1
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr17_+_48638371 0.35 ENST00000360761.4
ENST00000352832.5
ENST00000354983.4
CACNA1G
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr5_-_94620239 0.34 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr14_-_62162541 0.34 ENST00000557544.1
HIF1A-AS1
HIF1A antisense RNA 1
chr10_+_75757863 0.34 ENST00000372755.3
ENST00000211998.4
ENST00000417648.2
VCL
vinculin
chr2_-_61765732 0.34 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr12_+_70760056 0.34 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr11_-_115375107 0.34 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1
cell adhesion molecule 1
chr4_+_155665123 0.34 ENST00000336356.3
LRAT
lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)
chr2_+_10442993 0.33 ENST00000423674.1
ENST00000307845.3
HPCAL1
hippocalcin-like 1
chr2_+_203499901 0.33 ENST00000303116.6
ENST00000392238.2
FAM117B
family with sequence similarity 117, member B
chr3_+_112280857 0.33 ENST00000492406.1
ENST00000468642.1
SLC35A5
solute carrier family 35, member A5
chr12_-_54785054 0.32 ENST00000352268.6
ENST00000549962.1
ZNF385A
zinc finger protein 385A
chr20_-_56285595 0.32 ENST00000395816.3
ENST00000347215.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr18_+_3449695 0.31 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr1_+_157963063 0.31 ENST00000360089.4
ENST00000368173.3
ENST00000392272.2
KIRREL
kin of IRRE like (Drosophila)
chr2_-_220408260 0.31 ENST00000373891.2
CHPF
chondroitin polymerizing factor
chr2_+_70142189 0.31 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr7_+_114562909 0.30 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr1_+_151254738 0.30 ENST00000336715.6
ENST00000324048.5
ENST00000368879.2
ZNF687
zinc finger protein 687
chr7_-_129592471 0.30 ENST00000473814.2
ENST00000490974.1
UBE2H
ubiquitin-conjugating enzyme E2H
chr17_+_43299156 0.30 ENST00000331495.3
FMNL1
formin-like 1
chr16_-_30134266 0.29 ENST00000484663.1
ENST00000478356.1
MAPK3
mitogen-activated protein kinase 3
chr1_+_155293702 0.29 ENST00000368347.4
RUSC1
RUN and SH3 domain containing 1
chr10_+_45869652 0.29 ENST00000542434.1
ENST00000374391.2
ALOX5
arachidonate 5-lipoxygenase
chr19_+_8455200 0.28 ENST00000601897.1
ENST00000594216.1
RAB11B
RAB11B, member RAS oncogene family
chr6_+_36165133 0.28 ENST00000446974.1
ENST00000454960.1
BRPF3
bromodomain and PHD finger containing, 3
chr3_-_121740969 0.28 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1
immunoglobulin-like domain containing receptor 1
chr7_+_116593536 0.28 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr19_+_4153598 0.28 ENST00000078445.2
ENST00000252587.3
ENST00000595923.1
ENST00000602257.1
ENST00000602147.1
CREB3L3
cAMP responsive element binding protein 3-like 3
chr1_+_145576007 0.28 ENST00000369298.1
PIAS3
protein inhibitor of activated STAT, 3
chr5_+_38845960 0.28 ENST00000502536.1
OSMR
oncostatin M receptor
chr6_-_29600559 0.28 ENST00000476670.1
GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr11_+_64053005 0.28 ENST00000538032.1
GPR137
G protein-coupled receptor 137
chr16_+_3070356 0.28 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr12_+_122064673 0.27 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr11_-_65321198 0.27 ENST00000530426.1
LTBP3
latent transforming growth factor beta binding protein 3
chr17_-_73874654 0.27 ENST00000254816.2
TRIM47
tripartite motif containing 47
chr19_-_4124079 0.27 ENST00000394867.4
ENST00000262948.5
MAP2K2
mitogen-activated protein kinase kinase 2
chr16_+_50582222 0.27 ENST00000268459.3
NKD1
naked cuticle homolog 1 (Drosophila)
chr4_-_89444883 0.27 ENST00000273968.4
PYURF
PIGY upstream reading frame
chr1_+_169075554 0.27 ENST00000367815.4
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_198126209 0.27 ENST00000367383.1
NEK7
NIMA-related kinase 7
chr5_-_78281623 0.27 ENST00000521117.1
ARSB
arylsulfatase B
chr1_+_202995611 0.27 ENST00000367240.2
PPFIA4
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr19_+_39989580 0.27 ENST00000596614.1
ENST00000205143.4
DLL3
delta-like 3 (Drosophila)
chr17_-_7145475 0.26 ENST00000571129.1
ENST00000571253.1
ENST00000573928.1
GABARAP
GABA(A) receptor-associated protein
chr17_+_30771279 0.26 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr1_+_41157671 0.26 ENST00000534399.1
ENST00000372653.1
NFYC
nuclear transcription factor Y, gamma
chr16_+_23569021 0.26 ENST00000567212.1
ENST00000567264.1
UBFD1
ubiquitin family domain containing 1
chr14_-_99947121 0.26 ENST00000329331.3
ENST00000436070.2
SETD3
SET domain containing 3
chr17_-_74733404 0.26 ENST00000508921.3
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
ENST00000359995.5
SRSF2
serine/arginine-rich splicing factor 2
chr13_-_45151259 0.26 ENST00000493016.1
TSC22D1
TSC22 domain family, member 1
chr2_+_219081817 0.25 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr1_-_222885770 0.25 ENST00000355727.2
ENST00000340020.6
AIDA
axin interactor, dorsalization associated
chr1_-_205649580 0.25 ENST00000367145.3
SLC45A3
solute carrier family 45, member 3
chr1_+_6845384 0.25 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr7_+_143078652 0.25 ENST00000354434.4
ENST00000449423.2
ZYX
zyxin
chr6_+_110501621 0.25 ENST00000368930.1
ENST00000307731.1
CDC40
cell division cycle 40
chr6_+_110501344 0.24 ENST00000368932.1
CDC40
cell division cycle 40
chr17_-_80231300 0.24 ENST00000398519.5
ENST00000580446.1
CSNK1D
casein kinase 1, delta
chr2_+_70142232 0.24 ENST00000540449.1
MXD1
MAX dimerization protein 1
chr10_+_99258625 0.24 ENST00000370664.3
UBTD1
ubiquitin domain containing 1
chr15_-_59041768 0.24 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM10
ADAM metallopeptidase domain 10
chr19_+_38879061 0.24 ENST00000587013.1
SPRED3
sprouty-related, EVH1 domain containing 3
chr12_+_132312931 0.24 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr2_-_73511407 0.24 ENST00000520530.2
FBXO41
F-box protein 41
chr17_-_66287310 0.24 ENST00000582867.1
SLC16A6
solute carrier family 16, member 6
chr6_+_33168189 0.23 ENST00000444757.1
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr5_+_109025067 0.23 ENST00000261483.4
MAN2A1
mannosidase, alpha, class 2A, member 1
chr19_+_54372639 0.23 ENST00000391769.2
MYADM
myeloid-associated differentiation marker
chr1_-_154531095 0.23 ENST00000292211.4
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr12_-_93835665 0.23 ENST00000552442.1
ENST00000550657.1
UBE2N
ubiquitin-conjugating enzyme E2N
chr17_+_43299241 0.23 ENST00000328118.3
FMNL1
formin-like 1
chr1_+_145575980 0.23 ENST00000393045.2
PIAS3
protein inhibitor of activated STAT, 3
chr7_+_143079000 0.23 ENST00000392910.2
ZYX
zyxin
chr19_+_50270219 0.23 ENST00000354293.5
ENST00000359032.5
AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr2_+_220283091 0.23 ENST00000373960.3
DES
desmin
chr5_-_176037105 0.23 ENST00000303991.4
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr19_-_10047219 0.22 ENST00000264833.4
OLFM2
olfactomedin 2
chr1_+_112939121 0.22 ENST00000441739.1
CTTNBP2NL
CTTNBP2 N-terminal like
chr1_-_186344802 0.22 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr5_-_168006324 0.22 ENST00000522176.1
PANK3
pantothenate kinase 3
chr16_+_14927538 0.22 ENST00000287667.7
NOMO1
NODAL modulator 1
chr11_+_64052944 0.22 ENST00000535675.1
ENST00000543383.1
GPR137
G protein-coupled receptor 137
chr19_+_532049 0.22 ENST00000606136.1
CDC34
cell division cycle 34
chr19_+_39989535 0.22 ENST00000356433.5
DLL3
delta-like 3 (Drosophila)
chr3_-_184079382 0.22 ENST00000344937.7
ENST00000423355.2
ENST00000434054.2
ENST00000457512.1
ENST00000265593.4
CLCN2
chloride channel, voltage-sensitive 2
chr12_+_27091387 0.22 ENST00000544111.1
FGFR1OP2
FGFR1 oncogene partner 2
chr3_+_19988736 0.22 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr17_-_80231557 0.21 ENST00000392334.2
ENST00000314028.6
CSNK1D
casein kinase 1, delta
chr19_-_11456935 0.21 ENST00000590788.1
ENST00000586590.1
ENST00000589555.1
ENST00000586956.1
ENST00000593256.2
ENST00000447337.1
ENST00000591677.1
ENST00000586701.1
ENST00000589655.1
TMEM205
RAB3D
transmembrane protein 205
RAB3D, member RAS oncogene family
chr16_+_69600058 0.21 ENST00000393742.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr15_-_66084428 0.21 ENST00000443035.3
ENST00000431932.2
DENND4A
DENN/MADD domain containing 4A
chr5_+_86563636 0.21 ENST00000274376.6
RASA1
RAS p21 protein activator (GTPase activating protein) 1
chr3_-_49907323 0.21 ENST00000296471.7
ENST00000488336.1
ENST00000467248.1
ENST00000466940.1
ENST00000463537.1
ENST00000480398.2
CAMKV
CaM kinase-like vesicle-associated
chr20_-_524455 0.21 ENST00000349736.5
ENST00000217244.3
CSNK2A1
casein kinase 2, alpha 1 polypeptide
chr1_-_114696472 0.21 ENST00000393296.1
ENST00000369547.1
ENST00000610222.1
SYT6
synaptotagmin VI
chr14_-_51411194 0.21 ENST00000544180.2
PYGL
phosphorylase, glycogen, liver
chr1_+_157963391 0.21 ENST00000359209.6
ENST00000416935.2
KIRREL
kin of IRRE like (Drosophila)
chr1_-_91487806 0.21 ENST00000361321.5
ZNF644
zinc finger protein 644
chr17_+_30264014 0.21 ENST00000322652.5
ENST00000580398.1
SUZ12
SUZ12 polycomb repressive complex 2 subunit
chr2_+_7005959 0.20 ENST00000442639.1
RSAD2
radical S-adenosyl methionine domain containing 2
chr1_+_200993071 0.20 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr18_+_3449821 0.20 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr14_-_73924954 0.20 ENST00000555307.1
ENST00000554818.1
NUMB
numb homolog (Drosophila)
chr22_+_36784632 0.20 ENST00000424761.1
RP4-633O19__A.1
RP4-633O19__A.1
chr2_-_39348137 0.20 ENST00000426016.1
SOS1
son of sevenless homolog 1 (Drosophila)
chr16_-_30134441 0.20 ENST00000395200.1
MAPK3
mitogen-activated protein kinase 3
chr11_+_65686728 0.20 ENST00000312515.2
ENST00000525501.1
DRAP1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr7_+_100081542 0.19 ENST00000300179.2
ENST00000423930.1
NYAP1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr19_-_11494975 0.19 ENST00000222139.6
ENST00000592375.2
EPOR
erythropoietin receptor
chr1_-_113615699 0.19 ENST00000421157.1
RP11-31F15.2
RP11-31F15.2
chr16_+_68119440 0.19 ENST00000346183.3
ENST00000329524.4
NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chrX_+_48660287 0.19 ENST00000444343.2
ENST00000376610.2
ENST00000334136.5
ENST00000376619.2
HDAC6
histone deacetylase 6
chr16_-_49315731 0.19 ENST00000219197.6
CBLN1
cerebellin 1 precursor
chr15_+_66161871 0.19 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr11_-_65640071 0.19 ENST00000526624.1
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr1_-_44497024 0.18 ENST00000372306.3
ENST00000372310.3
ENST00000475075.2
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr14_-_99947168 0.18 ENST00000331768.5
SETD3
SET domain containing 3
chr19_-_31840438 0.18 ENST00000240587.4
TSHZ3
teashirt zinc finger homeobox 3
chr12_+_57482665 0.18 ENST00000300131.3
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr15_-_75744014 0.18 ENST00000394947.3
ENST00000565264.1
SIN3A
SIN3 transcription regulator family member A
chr1_+_40506255 0.18 ENST00000421589.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr19_+_8455077 0.18 ENST00000328024.6
RAB11B
RAB11B, member RAS oncogene family
chr1_+_160175117 0.18 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr1_+_40506392 0.18 ENST00000414893.1
ENST00000414281.1
ENST00000420216.1
ENST00000372792.2
ENST00000372798.1
ENST00000340450.3
ENST00000372805.3
ENST00000435719.1
ENST00000427843.1
ENST00000417287.1
ENST00000424977.1
ENST00000446031.1
CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr3_-_50540854 0.18 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
CACNA2D2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr17_-_56065540 0.18 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr14_+_89029323 0.18 ENST00000554602.1
ZC3H14
zinc finger CCCH-type containing 14
chr11_+_75526212 0.18 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr11_-_62521614 0.18 ENST00000527994.1
ENST00000394807.3
ZBTB3
zinc finger and BTB domain containing 3
chr19_-_11456905 0.18 ENST00000588560.1
ENST00000592952.1
TMEM205
transmembrane protein 205
chr6_+_160390102 0.18 ENST00000356956.1
IGF2R
insulin-like growth factor 2 receptor
chr14_-_24610779 0.18 ENST00000560403.1
ENST00000419198.2
ENST00000216799.4
EMC9
ER membrane protein complex subunit 9
chr12_+_53773944 0.18 ENST00000551969.1
ENST00000327443.4
SP1
Sp1 transcription factor
chr2_-_219850277 0.18 ENST00000295727.1
FEV
FEV (ETS oncogene family)
chr6_-_94129244 0.18 ENST00000369303.4
ENST00000369297.1
EPHA7
EPH receptor A7
chr1_+_160175201 0.18 ENST00000368076.1
PEA15
phosphoprotein enriched in astrocytes 15
chr12_-_49351148 0.18 ENST00000398092.4
ENST00000539611.1
RP11-302B13.5
ARF3
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr12_+_3000037 0.17 ENST00000544943.1
ENST00000448120.2
TULP3
tubby like protein 3
chr15_-_44487408 0.17 ENST00000402883.1
ENST00000417257.1
FRMD5
FERM domain containing 5
chr1_-_114302086 0.17 ENST00000369604.1
ENST00000357783.2
PHTF1
putative homeodomain transcription factor 1
chr14_+_101293687 0.17 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.3 0.8 GO:0090427 activation of meiosis(GO:0090427)
0.2 0.6 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.2 0.6 GO:2000656 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.2 0.9 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 0.2 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.1 0.7 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.1 0.4 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.6 GO:0061074 regulation of neural retina development(GO:0061074)
0.1 0.5 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.7 GO:0010609 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 1.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.3 GO:0045799 negative regulation of nucleobase-containing compound transport(GO:0032240) positive regulation of chromatin assembly or disassembly(GO:0045799) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.5 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.1 0.3 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.3 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.1 0.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.6 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.1 0.2 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 1.3 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 0.4 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.3 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 1.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.4 GO:1904693 midbrain morphogenesis(GO:1904693)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.3 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.4 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.2 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.1 0.2 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.2 GO:0060434 bronchus morphogenesis(GO:0060434)
0.1 0.2 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1 0.2 GO:1902232 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) regulation of positive thymic T cell selection(GO:1902232) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.2 GO:0051796 regulation of monophenol monooxygenase activity(GO:0032771) positive regulation of monophenol monooxygenase activity(GO:0032773) negative regulation of catagen(GO:0051796) regulation of hair cycle by canonical Wnt signaling pathway(GO:0060901) positive regulation of melanosome transport(GO:1902910)
0.1 0.2 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 0.2 GO:0010159 specification of organ position(GO:0010159)
0.1 0.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.2 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 0.1 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.2 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.3 GO:1902460 mesenchymal stem cell proliferation(GO:0097168) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.0 0.1 GO:1902824 positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 0.2 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.5 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.3 GO:1903288 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.0 0.3 GO:0007386 compartment pattern specification(GO:0007386)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.5 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.3 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.3 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.7 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.3 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.8 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0035910 noradrenergic neuron differentiation(GO:0003357) N-terminal peptidyl-lysine acetylation(GO:0018076) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.3 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0051036 regulation of endosome size(GO:0051036)
0.0 0.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.5 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.1 GO:1990791 glial cell fate determination(GO:0007403) negative regulation of mitotic cell cycle, embryonic(GO:0045976) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793) dorsal root ganglion development(GO:1990791)
0.0 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:0072047 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) pattern specification involved in metanephros development(GO:0072268)
0.0 0.5 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.1 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.0 0.4 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.1 GO:0030862 positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.0 0.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 0.3 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.2 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.5 GO:0051014 actin filament severing(GO:0051014)
0.0 0.5 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.2 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.1 GO:0051511 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) regulation of barbed-end actin filament capping(GO:2000812) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0 0.6 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.0 0.1 GO:0035544 negative regulation of SNARE complex assembly(GO:0035544)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.2 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0042756 drinking behavior(GO:0042756)
0.0 0.4 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.2 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.4 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:1903597 negative regulation of gap junction assembly(GO:1903597)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.3 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.0 0.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.2 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.0 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.0 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.1 GO:0022614 membrane to membrane docking(GO:0022614) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.0 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.1 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.0 0.2 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.3 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.3 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.3 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 0.5 GO:0032021 NELF complex(GO:0032021)
0.1 0.2 GO:0043257 laminin-8 complex(GO:0043257)
0.1 0.4 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 0.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.8 GO:0000124 SAGA complex(GO:0000124)
0.0 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.5 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.7 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.6 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.4 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.5 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 1.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.0 GO:0055087 Ski complex(GO:0055087)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.6 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.4 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.4 GO:0008184 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.1 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 0.6 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.3 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.2 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.3 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.2 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.3 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.7 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.0 1.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.6 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.1 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.8 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0016416 O-palmitoyltransferase activity(GO:0016416)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.6 GO:0005522 profilin binding(GO:0005522)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.6 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.4 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.0 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.0 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.0 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 1.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 1.5 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.9 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 3.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 1.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.4 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.8 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.7 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.4 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects