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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for KLF3

Z-value: 2.18

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Transcription factors associated with KLF3

Gene Symbol Gene ID Gene Info
ENSG00000109787.8 Kruppel like factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF3hg19_v2_chr4_+_38665810_38665827-0.683.2e-01Click!

Activity profile of KLF3 motif

Sorted Z-values of KLF3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_64764435 2.72 ENST00000534177.1
ENST00000301887.4
basic leucine zipper transcription factor, ATF-like 2
chr8_-_145060593 2.43 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
poly (ADP-ribose) polymerase family, member 10
chr17_+_38171681 2.34 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
colony stimulating factor 3 (granulocyte)
chr12_+_113344811 1.63 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_56753858 1.51 ENST00000314128.4
ENST00000557235.1
ENST00000418572.2
signal transducer and activator of transcription 2, 113kDa
chr17_+_38171614 1.40 ENST00000583218.1
ENST00000394149.3
colony stimulating factor 3 (granulocyte)
chr22_-_36635563 1.28 ENST00000451256.2
apolipoprotein L, 2
chr9_+_100174344 1.26 ENST00000422139.2
tudor domain containing 7
chr22_-_36635225 1.24 ENST00000529194.1
apolipoprotein L, 2
chr17_-_15496722 1.23 ENST00000472534.1
CMT1A duplicated region transcript 1
chr19_+_8429031 1.20 ENST00000301455.2
ENST00000541807.1
ENST00000393962.2
angiopoietin-like 4
chr11_+_60691924 1.19 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
transmembrane protein 132A
chr11_+_118826999 1.17 ENST00000264031.2
uroplakin 2
chr12_+_111843749 1.14 ENST00000341259.2
SH2B adaptor protein 3
chr20_+_2795609 1.14 ENST00000554164.1
ENST00000380593.4
transmembrane protein 239
CDNA FLJ26142 fis, clone TST04526; Transmembrane protein 239; Uncharacterized protein
chr19_-_44174330 1.13 ENST00000340093.3
plasminogen activator, urokinase receptor
chr19_+_677885 1.11 ENST00000591552.2
follistatin-like 3 (secreted glycoprotein)
chr17_+_73750699 1.10 ENST00000584939.1
integrin, beta 4
chr22_-_50970566 1.09 ENST00000405135.1
ENST00000401779.1
outer dense fiber of sperm tails 3B
chr6_+_144471643 1.08 ENST00000367568.4
syntaxin 11
chr17_+_33914424 1.05 ENST00000590432.1
adaptor-related protein complex 2, beta 1 subunit
chr22_-_50970506 1.03 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr15_+_67430339 0.99 ENST00000439724.3
SMAD family member 3
chr7_+_302918 0.93 ENST00000599994.1
Protein LOC100996433
chr17_+_79989500 0.93 ENST00000306897.4
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr19_-_44174305 0.92 ENST00000601723.1
ENST00000339082.3
plasminogen activator, urokinase receptor
chr19_-_10213335 0.91 ENST00000592641.1
ENST00000253109.4
angiopoietin-like 6
chr17_+_33914460 0.90 ENST00000537622.2
adaptor-related protein complex 2, beta 1 subunit
chr17_+_7482785 0.89 ENST00000250092.6
ENST00000380498.6
ENST00000584502.1
CD68 molecule
chr1_+_19967014 0.85 ENST00000428975.1
neuroblastoma 1, DAN family BMP antagonist
chr20_+_61299155 0.85 ENST00000451793.1
solute carrier organic anion transporter family, member 4A1
chr11_-_64512273 0.84 ENST00000377497.3
ENST00000377487.1
ENST00000430645.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_+_33914276 0.83 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
adaptor-related protein complex 2, beta 1 subunit
chr17_-_76870126 0.82 ENST00000586057.1
TIMP metallopeptidase inhibitor 2
chr12_-_96390108 0.80 ENST00000538703.1
ENST00000261208.3
histidine ammonia-lyase
chr8_-_23712312 0.79 ENST00000290271.2
stanniocalcin 1
chrX_-_153141302 0.77 ENST00000361699.4
ENST00000543994.1
ENST00000370057.3
ENST00000538883.1
ENST00000361981.3
L1 cell adhesion molecule
chr5_+_135385202 0.77 ENST00000514554.1
transforming growth factor, beta-induced, 68kDa
chr6_-_41254403 0.77 ENST00000589614.1
ENST00000334475.6
ENST00000591620.1
ENST00000244709.4
triggering receptor expressed on myeloid cells 1
chr11_+_64053311 0.75 ENST00000540370.1
G protein-coupled receptor 137
chr5_-_90610200 0.74 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr12_-_96389702 0.73 ENST00000552509.1
histidine ammonia-lyase
chr1_-_6445809 0.72 ENST00000377855.2
acyl-CoA thioesterase 7
chr3_-_120169828 0.72 ENST00000424703.2
ENST00000469005.1
follistatin-like 1
chr3_+_11196206 0.72 ENST00000431010.2
histamine receptor H1
chr8_-_110988070 0.72 ENST00000524391.1
potassium channel, subfamily V, member 1
chr19_-_40730820 0.71 ENST00000513948.1
cyclin N-terminal domain containing 2
chr11_-_61658853 0.70 ENST00000525588.1
ENST00000540820.1
fatty acid desaturase 3
chr17_+_79405396 0.70 ENST00000571813.2
BAH and coiled-coil domain-containing protein 1
chr20_+_61287711 0.68 ENST00000370507.1
solute carrier organic anion transporter family, member 4A1
chr8_-_123793048 0.68 ENST00000607710.1
RP11-44N11.2
chr13_+_52158610 0.68 ENST00000298125.5
WD repeat and FYVE domain containing 2
chr11_-_47616210 0.67 ENST00000302514.3
C1q and tumor necrosis factor related protein 4
chr17_+_40118805 0.66 ENST00000591072.1
ENST00000587679.1
ENST00000393888.1
ENST00000441615.2
2',3'-cyclic nucleotide 3' phosphodiesterase
chr11_+_57365150 0.66 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr11_-_61659006 0.65 ENST00000278829.2
fatty acid desaturase 3
chr17_+_40118773 0.65 ENST00000472031.1
2',3'-cyclic nucleotide 3' phosphodiesterase
chr19_+_41107249 0.64 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chrX_-_153151586 0.64 ENST00000370060.1
ENST00000370055.1
ENST00000420165.1
L1 cell adhesion molecule
chr3_-_5229982 0.63 ENST00000600805.1
Uncharacterized protein
chr22_-_50964558 0.63 ENST00000535425.1
ENST00000439934.1
SCO2 cytochrome c oxidase assembly protein
chr11_-_4414880 0.62 ENST00000254436.7
ENST00000543625.1
tripartite motif containing 21
chr2_+_169923577 0.61 ENST00000432060.2
dehydrogenase/reductase (SDR family) member 9
chr19_-_38806540 0.61 ENST00000592694.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr15_-_74495188 0.60 ENST00000563965.1
ENST00000395105.4
stimulated by retinoic acid 6
chr1_-_23521222 0.60 ENST00000374619.1
5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
chr17_-_62207485 0.60 ENST00000433197.3
endoplasmic reticulum to nucleus signaling 1
chr15_+_63334831 0.59 ENST00000288398.6
ENST00000358278.3
ENST00000560445.1
ENST00000403994.3
ENST00000357980.4
ENST00000559556.1
ENST00000559397.1
ENST00000267996.7
ENST00000560970.1
tropomyosin 1 (alpha)
chr2_+_233243233 0.59 ENST00000392027.2
alkaline phosphatase, placental
chr1_+_44401479 0.57 ENST00000438616.3
artemin
chr22_-_51017084 0.57 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
carnitine palmitoyltransferase 1B (muscle)
chr12_+_7169887 0.56 ENST00000542978.1
complement component 1, s subcomponent
chr12_+_52404270 0.55 ENST00000552049.1
ENST00000546756.1
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr3_-_124560257 0.54 ENST00000496703.1
integrin, beta 5
chr17_+_40118759 0.53 ENST00000393892.3
2',3'-cyclic nucleotide 3' phosphodiesterase
chr12_-_7244469 0.53 ENST00000538050.1
ENST00000536053.2
complement component 1, r subcomponent
chr10_+_35484053 0.53 ENST00000487763.1
ENST00000473940.1
ENST00000488328.1
ENST00000356917.5
cAMP responsive element modulator
chr22_+_38071615 0.53 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr2_+_85132749 0.52 ENST00000233143.4
thymosin beta 10
chr20_+_46130671 0.52 ENST00000371998.3
ENST00000371997.3
nuclear receptor coactivator 3
chr19_+_19303572 0.52 ENST00000407360.3
ENST00000540981.1
regulatory factor X-associated ankyrin-containing protein
chr18_-_61329118 0.51 ENST00000332821.8
ENST00000283752.5
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr19_-_51289374 0.51 ENST00000563228.1
CTD-2568A17.1
chr8_-_61566092 0.51 ENST00000529518.1
RP11-91I20.2
chrX_-_52260355 0.51 ENST00000375602.1
ENST00000399800.3
X antigen family, member 1A
chr19_+_1941117 0.50 ENST00000255641.8
casein kinase 1, gamma 2
chr9_-_16705069 0.50 ENST00000471301.2
basonuclin 2
chr11_-_62313090 0.49 ENST00000528508.1
ENST00000533365.1
AHNAK nucleoprotein
chr7_+_870547 0.49 ENST00000457598.1
Sad1 and UNC84 domain containing 1
chr9_+_107509944 0.49 ENST00000374767.4
nipsnap homolog 3A (C. elegans)
chr10_+_101419187 0.49 ENST00000370489.4
ectonucleoside triphosphate diphosphohydrolase 7
chr1_+_6511651 0.48 ENST00000434576.1
espin
chr16_+_2213530 0.48 ENST00000567645.1
TNF receptor-associated factor 7, E3 ubiquitin protein ligase
chr12_-_49351148 0.47 ENST00000398092.4
ENST00000539611.1
ADP-ribosylation factor 3
ADP-ribosylation factor 3
chr17_+_79859985 0.47 ENST00000333383.7
neuropeptide B
chr19_+_54135310 0.47 ENST00000376650.1
divergent-paired related homeobox
chr15_-_101817492 0.46 ENST00000528346.1
ENST00000531964.1
VCP-interacting membrane protein
chr2_+_74881355 0.46 ENST00000357877.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr5_+_86415919 0.45 ENST00000515750.1
RP11-72L22.1
chrX_+_52511761 0.45 ENST00000399795.3
ENST00000375589.1
X antigen family, member 1C
chr14_-_21491305 0.45 ENST00000554531.1
NDRG family member 2
chr17_+_6939362 0.45 ENST00000308027.6
solute carrier family 16, member 13
chrX_+_133941218 0.44 ENST00000370784.4
ENST00000370785.3
family with sequence similarity 122C
chr4_-_185820602 0.44 ENST00000515864.1
ENST00000507183.1
long intergenic non-protein coding RNA 1093
chr19_-_50836762 0.44 ENST00000474951.1
ENST00000391818.2
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr6_-_31651817 0.44 ENST00000375863.3
ENST00000375860.2
lymphocyte antigen 6 complex, locus G5C
chr3_+_51976338 0.44 ENST00000417220.2
ENST00000431474.1
ENST00000398755.3
poly (ADP-ribose) polymerase family, member 3
chr20_+_43803517 0.43 ENST00000243924.3
peptidase inhibitor 3, skin-derived
chr11_-_64512803 0.43 ENST00000377489.1
ENST00000354024.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_60010556 0.43 ENST00000427611.2
membrane-spanning 4-domains, subfamily A, member 4E
chr12_+_121088291 0.43 ENST00000351200.2
calcium binding protein 1
chr17_+_47210125 0.42 ENST00000393354.2
beta-1,4-N-acetyl-galactosaminyl transferase 2
chr19_+_676385 0.42 ENST00000166139.4
follistatin-like 3 (secreted glycoprotein)
chr19_-_38806560 0.42 ENST00000591755.1
ENST00000337679.8
ENST00000339413.6
Yip1 interacting factor homolog B (S. cerevisiae)
chrX_-_52260199 0.42 ENST00000375600.1
X antigen family, member 1A
chr7_+_26191809 0.42 ENST00000056233.3
nuclear factor, erythroid 2-like 3
chr11_-_64511575 0.42 ENST00000431822.1
ENST00000377486.3
ENST00000394432.3
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr2_+_169923504 0.42 ENST00000357546.2
dehydrogenase/reductase (SDR family) member 9
chr1_+_180165672 0.42 ENST00000443059.1
quiescin Q6 sulfhydryl oxidase 1
chr17_-_27181990 0.41 ENST00000583953.1
family with sequence similarity 222, member B
chr19_+_19303008 0.41 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
regulatory factor X-associated ankyrin-containing protein
chr19_-_1132207 0.41 ENST00000438103.2
strawberry notch homolog 2 (Drosophila)
chr20_-_17641097 0.41 ENST00000246043.4
ribosome binding protein 1
chr12_-_96390063 0.41 ENST00000541929.1
histidine ammonia-lyase
chrX_-_52533139 0.41 ENST00000374959.3
X antigen family, member 1D
chr16_+_1578674 0.41 ENST00000253934.5
transmembrane protein 204
chr10_-_112064665 0.41 ENST00000369603.5
survival motor neuron domain containing 1
chrX_+_52238810 0.40 ENST00000437949.2
ENST00000375616.1
X antigen family, member 1B
chr22_-_51016846 0.39 ENST00000312108.7
ENST00000395650.2
carnitine palmitoyltransferase 1B (muscle)
chr11_+_65647280 0.39 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
cathepsin W
chr4_-_168155730 0.39 ENST00000502330.1
ENST00000357154.3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr15_-_67351586 0.39 ENST00000558071.1
RP11-798K3.2
chr19_-_38806390 0.39 ENST00000589247.1
ENST00000329420.8
ENST00000591784.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr17_+_36873677 0.39 ENST00000471200.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_+_58033450 0.38 ENST00000561743.1
U6 snRNA biogenesis 1
chr5_+_151151471 0.38 ENST00000394123.3
ENST00000543466.1
GTPase activating protein (SH3 domain) binding protein 1
chr2_+_71295733 0.38 ENST00000443938.2
ENST00000244204.6
N-acetylglucosamine kinase
chrX_+_52511925 0.38 ENST00000375588.1
X antigen family, member 1C
chr2_-_192015697 0.38 ENST00000409995.1
signal transducer and activator of transcription 4
chr1_+_206680879 0.38 ENST00000355294.4
ENST00000367117.3
Ras association (RalGDS/AF-6) domain family member 5
chr2_+_210288760 0.37 ENST00000199940.6
microtubule-associated protein 2
chr14_-_24711470 0.37 ENST00000559969.1
TERF1 (TRF1)-interacting nuclear factor 2
chrX_-_70326455 0.37 ENST00000374251.5
chromosome X open reading frame 65
chr11_+_65407331 0.36 ENST00000527525.1
signal-induced proliferation-associated 1
chr11_-_65793948 0.36 ENST00000312106.5
cation channel, sperm associated 1
chr22_-_36850991 0.36 ENST00000442579.1
RP5-1119A7.14
chrX_-_47489244 0.35 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
complement factor properdin
chr7_-_100491854 0.35 ENST00000426415.1
ENST00000430554.1
ENST00000412389.1
acetylcholinesterase (Yt blood group)
chr8_+_124194875 0.35 ENST00000522648.1
ENST00000276699.6
family with sequence similarity 83, member A
chrX_-_52533295 0.35 ENST00000375578.1
ENST00000396497.3
X antigen family, member 1D
chr22_-_30722912 0.35 ENST00000215790.7
TBC1 domain family, member 10A
chr11_-_57194948 0.35 ENST00000533235.1
ENST00000526621.1
ENST00000352187.1
solute carrier family 43, member 3
chr11_-_119252425 0.35 ENST00000260187.2
ubiquitin specific peptidase 2
chr19_+_4007644 0.35 ENST00000262971.2
protein inhibitor of activated STAT, 4
chr16_+_89989687 0.35 ENST00000315491.7
ENST00000555576.1
ENST00000554336.1
ENST00000553967.1
Tubulin beta-3 chain
chr11_-_64512469 0.35 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_+_79071365 0.34 ENST00000576756.1
BAI1-associated protein 2
chr19_+_50321528 0.34 ENST00000312865.6
ENST00000595185.1
ENST00000538643.1
mediator complex subunit 25
chr1_+_207494853 0.34 ENST00000367064.3
ENST00000367063.2
ENST00000391921.4
ENST00000367067.4
ENST00000314754.8
ENST00000367065.5
ENST00000391920.4
ENST00000367062.4
ENST00000343420.6
CD55 molecule, decay accelerating factor for complement (Cromer blood group)
chr15_-_62457480 0.34 ENST00000380392.3
C2 calcium-dependent domain containing 4B
chr1_-_159869912 0.34 ENST00000368099.4
coiled-coil domain containing 19
chrX_-_52546189 0.34 ENST00000375570.1
ENST00000429372.2
X antigen family, member 1E
chr19_+_39279838 0.33 ENST00000314980.4
lectin, galactoside-binding, soluble, 7B
chr2_+_54951679 0.33 ENST00000356458.6
echinoderm microtubule associated protein like 6
chr16_-_3086927 0.33 ENST00000572449.1
coiled-coil domain containing 64B
chr22_-_30722866 0.33 ENST00000403477.3
TBC1 domain family, member 10A
chrX_-_52546033 0.33 ENST00000375567.3
X antigen family, member 1E
chr2_+_71295717 0.33 ENST00000418807.3
ENST00000443872.2
N-acetylglucosamine kinase
chr6_+_34725181 0.33 ENST00000244520.5
small nuclear ribonucleoprotein polypeptide C
chr6_+_142623758 0.33 ENST00000541199.1
ENST00000435011.2
G protein-coupled receptor 126
chr2_+_233734994 0.32 ENST00000331342.2
chromosome 2 open reading frame 82
chr19_+_8455200 0.32 ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chr6_+_138725343 0.32 ENST00000607197.1
ENST00000367697.3
heme binding protein 2
chr9_-_135819987 0.32 ENST00000298552.3
ENST00000403810.1
tuberous sclerosis 1
chr19_-_13213662 0.32 ENST00000264824.4
lymphoblastic leukemia derived sequence 1
chr16_+_55600580 0.32 ENST00000457326.2
calpain, small subunit 2
chr11_-_119252359 0.32 ENST00000455332.2
ubiquitin specific peptidase 2
chr12_-_113772835 0.32 ENST00000552014.1
ENST00000548186.1
ENST00000202831.3
ENST00000549181.1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr1_-_57045228 0.32 ENST00000371250.3
phosphatidic acid phosphatase type 2B
chr1_+_152178320 0.31 ENST00000429352.1
RP11-107M16.2
chr16_-_18573396 0.31 ENST00000543392.1
ENST00000381474.3
ENST00000330537.6
NODAL modulator 2
chr22_+_39916558 0.31 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr11_-_414948 0.31 ENST00000530494.1
ENST00000528209.1
ENST00000431843.2
ENST00000528058.1
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr14_-_24711806 0.31 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TERF1 (TRF1)-interacting nuclear factor 2
chr11_+_71498552 0.30 ENST00000346333.6
ENST00000359244.4
ENST00000426628.2
family with sequence similarity 86, member C1
chr1_-_28520447 0.30 ENST00000539896.1
platelet-activating factor receptor
chr15_-_88795835 0.30 ENST00000559188.1
neurotrophic tyrosine kinase, receptor, type 3
chr15_-_60690932 0.30 ENST00000559818.1
annexin A2
chr2_-_26205340 0.30 ENST00000264712.3
kinesin family member 3C
chr11_-_57194919 0.30 ENST00000532795.1
solute carrier family 43, member 3
chr12_-_31478428 0.30 ENST00000543615.1
family with sequence similarity 60, member A
chr12_-_54121261 0.30 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr4_-_69083720 0.30 ENST00000432593.3
TMPRSS11B N-terminal like
chr8_-_145642267 0.29 ENST00000301305.3
solute carrier family 39 (zinc transporter), member 4
chr14_-_105635090 0.29 ENST00000331782.3
ENST00000347004.2
jagged 2
chr11_+_46638805 0.29 ENST00000434074.1
ENST00000312040.4
ENST00000451945.1
autophagy related 13
chr16_-_1020954 0.29 ENST00000543238.1
ENST00000539379.1
ENST00000399843.2
ENST00000262301.11
lipase maturation factor 1
chr9_+_112403088 0.29 ENST00000448454.2
paralemmin 2
chr3_+_107364683 0.29 ENST00000413213.1
bobby sox homolog (Drosophila)
chr17_-_36760865 0.29 ENST00000584266.1
SRC kinase signaling inhibitor 1

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.4 3.7 GO:0030223 neutrophil differentiation(GO:0030223)
0.3 2.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 1.9 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3 2.1 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.2 0.9 GO:0006050 mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
0.2 0.7 GO:0036116 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.2 0.9 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.2 0.6 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 1.0 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 1.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.5 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.8 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 3.0 GO:0042832 defense response to protozoan(GO:0042832)
0.1 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.4 GO:0045212 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 1.5 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 0.8 GO:0035624 receptor transactivation(GO:0035624)
0.1 1.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.5 GO:0035900 response to isolation stress(GO:0035900)
0.1 0.4 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.3 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.3 GO:1904303 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.1 0.6 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.3 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.1 0.6 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.8 GO:1901142 insulin metabolic process(GO:1901142)
0.1 0.3 GO:0036034 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.1 0.9 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.2 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.1 0.2 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.7 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.1 0.9 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.1 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.3 GO:0052026 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.3 GO:0044115 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.6 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 0.8 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.4 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.1 GO:0043449 cellular alkene metabolic process(GO:0043449)
0.1 0.6 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.1 0.2 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.3 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 1.1 GO:0035878 nail development(GO:0035878)
0.1 0.3 GO:0051029 rRNA transport(GO:0051029)
0.1 0.6 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.5 GO:2000782 regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.8 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 0.2 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764) regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.2 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.3 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.2 GO:0052651 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.1 0.4 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.3 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.4 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0002522 leukocyte migration involved in immune response(GO:0002522)
0.0 0.3 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.2 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.4 GO:0070885 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.5 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.0 1.0 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.6 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0010732 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
0.0 0.4 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276) lipid glycosylation(GO:0030259)
0.0 1.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 1.1 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 2.5 GO:0006953 acute-phase response(GO:0006953)
0.0 0.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 1.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.6 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.4 GO:0035860 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.4 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.6 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 2.0 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 0.2 GO:2000468 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of hydrogen peroxide catabolic process(GO:2000295) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:0009233 coenzyme catabolic process(GO:0009109) menaquinone metabolic process(GO:0009233) ketone catabolic process(GO:0042182) menaquinone catabolic process(GO:0042361) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) vitamin K catabolic process(GO:0042377) quinone catabolic process(GO:1901662)
0.0 0.1 GO:0097327 response to antineoplastic agent(GO:0097327)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0090071 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709) negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.1 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0019860 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) beta-alanine metabolic process(GO:0019482) thymine metabolic process(GO:0019859) uracil metabolic process(GO:0019860)
0.0 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.0 0.2 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.3 GO:0009912 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.4 GO:0016576 histone dephosphorylation(GO:0016576) positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.2 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.4 GO:0007620 copulation(GO:0007620)
0.0 0.2 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.1 GO:0030185 nitric oxide transport(GO:0030185)
0.0 0.3 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.0 0.3 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.5 GO:0031629 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.1 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.2 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.1 GO:2000768 glomerular parietal epithelial cell differentiation(GO:0072139) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.0 1.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.4 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.6 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 1.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 1.4 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.1 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.5 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.5 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.2 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.4 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.2 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0098780 macromitophagy(GO:0000423) response to mitochondrial depolarisation(GO:0098780)
0.0 1.4 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.3 GO:0030336 negative regulation of cell migration(GO:0030336)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.0 0.4 GO:0001945 lymph vessel development(GO:0001945)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.0 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.2 GO:0034375 high-density lipoprotein particle remodeling(GO:0034375)
0.0 0.1 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.1 GO:0097646 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0070970 interleukin-2 secretion(GO:0070970)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.2 2.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.5 GO:0034684 integrin alphav-beta5 complex(GO:0034684)
0.1 2.1 GO:0071438 invadopodium membrane(GO:0071438)
0.1 3.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.2 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 1.2 GO:0033391 chromatoid body(GO:0033391)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0034515 proteasome storage granule(GO:0034515)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 2.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.3 GO:0000243 commitment complex(GO:0000243)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.4 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.3 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 1.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.5 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 1.3 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 1.8 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.2 GO:0005901 caveola(GO:0005901)
0.0 0.2 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.5 1.8 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.3 2.1 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.2 0.9 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.2 0.5 GO:0030395 lactose binding(GO:0030395)
0.2 1.5 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.0 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 2.5 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.1 1.6 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 1.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.1 0.3 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.1 0.8 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 3.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.3 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.1 1.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.4 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.4 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 1.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.9 GO:0016015 morphogen activity(GO:0016015)
0.1 0.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 1.4 GO:0048185 activin binding(GO:0048185)
0.1 2.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.2 GO:0008124 phenylalanine 4-monooxygenase activity(GO:0004505) 4-alpha-hydroxytetrahydrobiopterin dehydratase activity(GO:0008124)
0.1 0.6 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 2.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.6 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.2 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.2 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.5 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.3 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.4 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.3 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.1 GO:0032440 2-alkenal reductase [NAD(P)] activity(GO:0032440)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.1 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.0 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.6 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0001602 pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0099529 postsynaptic neurotransmitter receptor activity(GO:0098960) neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.2 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 4.7 GO:0005125 cytokine activity(GO:0005125)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.7 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:1902444 riboflavin binding(GO:1902444)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.6 GO:0008200 ion channel inhibitor activity(GO:0008200)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851) ICAM-3 receptor activity(GO:0030369)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.9 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 0.3 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.1 3.7 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 8.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.9 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 1.8 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.1 0.6 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 1.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.0 2.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.9 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade