Project
A549 cells infected with RSV Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for KLF16_SP2
Z-value: 1.76
Motif logo
Transcription factors associated with KLF16_SP2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SP2 | hg19_v2_chr17_+_45973516_45973618 | 0.55 | 4.5e-01 | Click! |
| KLF16 | hg19_v2_chr19_-_1863567_1863586 | 0.20 | 8.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr19_-_39832563 Show fit | 0.81 |
ENST00000599274.1
|
CTC-246B18.10 |
|
| chr19_+_36132631 Show fit | 0.79 |
ENST00000379026.2
ENST00000379023.4 ENST00000402764.2 ENST00000479824.1 |
ets variant 2 |
|
| chr11_+_130184888 Show fit | 0.78 |
ENST00000602376.1
ENST00000532116.3 ENST00000602310.1 |
RP11-121M22.1 |
|
| chr19_-_40971643 Show fit | 0.75 |
ENST00000595483.1
|
biliverdin reductase B (flavin reductase (NADPH)) |
|
| chr3_+_238969 Show fit | 0.73 |
ENST00000421198.1
|
cell adhesion molecule L1-like |
|
| chr12_+_123849462 Show fit | 0.68 |
ENST00000543072.1
|
hsa-mir-8072 |
|
| chr11_+_64008525 Show fit | 0.67 |
ENST00000449942.2
|
FK506 binding protein 2, 13kDa |
|
| chr4_+_186392597 Show fit | 0.65 |
ENST00000512874.1
|
Uncharacterized protein |
|
| chr12_-_58145889 Show fit | 0.64 |
ENST00000547853.1
|
cyclin-dependent kinase 4 |
|
| chr19_-_19739321 Show fit | 0.63 |
ENST00000588461.1
|
lysophosphatidic acid receptor 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of KLF16_SP2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.6 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 2.6 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.1 | 1.6 | GO:0042167 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.1 | 1.5 | GO:0032075 | positive regulation of nuclease activity(GO:0032075) |
| 0.0 | 1.5 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 1.4 | GO:0010257 | NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031) |
| 0.4 | 1.3 | GO:1903461 | Okazaki fragment processing involved in mitotic DNA replication(GO:1903461) |
| 0.0 | 1.2 | GO:2001222 | regulation of neuron migration(GO:2001222) |
| 0.1 | 1.1 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 0.1 | 1.1 | GO:0060613 | fat pad development(GO:0060613) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 2.4 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 0.0 | 1.5 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.1 | 1.2 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.0 | 1.2 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.1 | 1.1 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.0 | 1.1 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 1.1 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 1.0 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.0 | 1.0 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.3 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 2.2 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.0 | 1.5 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 1.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.4 | 1.4 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.0 | 1.4 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.1 | 1.3 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.0 | 1.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 1.3 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) |
| 0.0 | 1.2 | GO:0051087 | chaperone binding(GO:0051087) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.6 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.0 | 2.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 1.8 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.0 | 1.8 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 1.5 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.4 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 1.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 1.1 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 1.1 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.9 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.7 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 2.6 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.0 | 2.6 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 2.4 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 1.8 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 1.7 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.1 | 1.6 | REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | Genes involved in Processive synthesis on the lagging strand |
| 0.0 | 1.6 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 1.5 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 1.5 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |