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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for KLF12

Z-value: 1.35

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Transcription factors associated with KLF12

Gene Symbol Gene ID Gene Info
KLF12
ENSG00000118922.12 Kruppel like factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
KLF12hg19_v2_chr13_-_74708372_747084090.861.4e-01Click!

Activity profile of KLF12 motif

Sorted Z-values of KLF12 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_153750622 1.00 ENST00000532853.1
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr12_-_56120838 0.66 ENST00000548160.1
CD63
CD63 molecule
chr22_-_39268308 0.58 ENST00000407418.3
CBX6
chromobox homolog 6
chr4_-_5710257 0.57 ENST00000344938.1
ENST00000344408.5
EVC2
Ellis van Creveld syndrome 2
chr17_+_27071002 0.51 ENST00000262395.5
ENST00000422344.1
ENST00000444415.3
ENST00000262396.6
TRAF4
TNF receptor-associated factor 4
chr12_-_56120865 0.50 ENST00000548898.1
ENST00000552067.1
CD63
CD63 molecule
chr6_-_107436473 0.48 ENST00000369042.1
BEND3
BEN domain containing 3
chr17_+_1665253 0.46 ENST00000254722.4
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr5_-_139930713 0.44 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr4_+_3443614 0.42 ENST00000382774.3
ENST00000511533.1
HGFAC
HGF activator
chr17_+_4618734 0.42 ENST00000571206.1
ARRB2
arrestin, beta 2
chr12_-_56881874 0.41 ENST00000539272.1
GLS2
glutaminase 2 (liver, mitochondrial)
chr19_-_5785630 0.40 ENST00000586012.1
ENST00000590343.1
CTB-54O9.9
DUS3L
Uncharacterized protein
dihydrouridine synthase 3-like (S. cerevisiae)
chr17_-_41174367 0.39 ENST00000587173.1
VAT1
vesicle amine transport 1
chr2_+_231902193 0.39 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr16_-_67978016 0.37 ENST00000264005.5
LCAT
lecithin-cholesterol acyltransferase
chr14_-_104181771 0.37 ENST00000554913.1
ENST00000554974.1
ENST00000553361.1
ENST00000555055.1
ENST00000555964.1
ENST00000556682.1
ENST00000445556.1
ENST00000553332.1
ENST00000352127.7
XRCC3
X-ray repair complementing defective repair in Chinese hamster cells 3
chr17_-_36891830 0.36 ENST00000578487.1
PCGF2
polycomb group ring finger 2
chr22_-_39268192 0.36 ENST00000216083.6
CBX6
chromobox homolog 6
chr14_+_65171315 0.35 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_74779744 0.35 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr15_+_40763150 0.35 ENST00000306243.5
ENST00000559991.1
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr18_+_56532053 0.35 ENST00000592452.1
ZNF532
zinc finger protein 532
chr7_+_65552756 0.35 ENST00000450043.1
AC068533.7
AC068533.7
chr7_+_66800928 0.34 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr10_-_77161004 0.34 ENST00000418818.2
RP11-399K21.11
RP11-399K21.11
chr11_+_117070037 0.34 ENST00000392951.4
ENST00000525531.1
ENST00000278968.6
TAGLN
transgelin
chr14_+_63671105 0.33 ENST00000316754.3
RHOJ
ras homolog family member J
chr2_-_85828867 0.32 ENST00000425160.1
TMEM150A
transmembrane protein 150A
chr12_+_7060414 0.32 ENST00000538715.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_+_75894391 0.31 ENST00000419727.2
JDP2
Jun dimerization protein 2
chr20_+_44637526 0.30 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr17_-_28257080 0.30 ENST00000579954.1
ENST00000540801.1
ENST00000269033.3
ENST00000590153.1
ENST00000582084.1
SSH2
slingshot protein phosphatase 2
chr8_-_30670053 0.30 ENST00000518564.1
PPP2CB
protein phosphatase 2, catalytic subunit, beta isozyme
chr3_-_61237050 0.30 ENST00000476844.1
ENST00000488467.1
ENST00000492590.1
ENST00000468189.1
FHIT
fragile histidine triad
chr18_+_29598335 0.29 ENST00000217740.3
RNF125
ring finger protein 125, E3 ubiquitin protein ligase
chr8_-_71519889 0.29 ENST00000521425.1
TRAM1
translocation associated membrane protein 1
chr21_+_38338737 0.29 ENST00000430068.1
AP000704.5
AP000704.5
chr16_+_28875126 0.29 ENST00000359285.5
ENST00000538342.1
SH2B1
SH2B adaptor protein 1
chr17_-_72864739 0.29 ENST00000579893.1
ENST00000544854.1
FDXR
ferredoxin reductase
chr9_+_131445703 0.28 ENST00000454747.1
SET
SET nuclear oncogene
chr14_+_70234642 0.28 ENST00000555349.1
ENST00000554021.1
SRSF5
serine/arginine-rich splicing factor 5
chr15_+_90118685 0.28 ENST00000268138.7
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr5_-_81046841 0.28 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr6_+_33168597 0.27 ENST00000374675.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr2_+_128180842 0.27 ENST00000402125.2
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr17_-_47045949 0.27 ENST00000357424.2
GIP
gastric inhibitory polypeptide
chr8_-_42698292 0.26 ENST00000529779.1
THAP1
THAP domain containing, apoptosis associated protein 1
chr11_-_57089671 0.26 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr8_-_25281747 0.26 ENST00000421054.2
GNRH1
gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr10_+_98741041 0.26 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr19_+_10812108 0.25 ENST00000250237.5
ENST00000592254.1
QTRT1
queuine tRNA-ribosyltransferase 1
chr17_+_28256874 0.25 ENST00000541045.1
ENST00000536908.2
EFCAB5
EF-hand calcium binding domain 5
chr9_-_35754253 0.25 ENST00000436428.2
MSMP
microseminoprotein, prostate associated
chr15_+_90118723 0.25 ENST00000560985.1
TICRR
TOPBP1-interacting checkpoint and replication regulator
chr11_-_22647350 0.25 ENST00000327470.3
FANCF
Fanconi anemia, complementation group F
chr17_+_1665345 0.25 ENST00000576406.1
ENST00000571149.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_-_3978083 0.25 ENST00000600794.1
EEF2
eukaryotic translation elongation factor 2
chr22_-_30198075 0.24 ENST00000411532.1
ASCC2
activating signal cointegrator 1 complex subunit 2
chr5_+_34656450 0.24 ENST00000514527.1
RAI14
retinoic acid induced 14
chr1_-_55341551 0.23 ENST00000537443.1
DHCR24
24-dehydrocholesterol reductase
chr18_+_52385068 0.23 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr19_+_45174724 0.23 ENST00000358777.4
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr14_+_65171099 0.23 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr12_+_120740119 0.23 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr7_-_43965937 0.23 ENST00000455877.1
ENST00000223341.7
ENST00000447717.3
ENST00000426198.1
URGCP
upregulator of cell proliferation
chr8_-_144512576 0.23 ENST00000333480.2
MAFA
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
chr11_-_64856497 0.23 ENST00000524632.1
ENST00000530719.1
AP003068.6
transmembrane protein 262
chr17_-_27277615 0.22 ENST00000583747.1
ENST00000584236.1
PHF12
PHD finger protein 12
chr6_+_33168637 0.22 ENST00000374677.3
SLC39A7
solute carrier family 39 (zinc transporter), member 7
chr14_-_61190754 0.22 ENST00000216513.4
SIX4
SIX homeobox 4
chr12_-_120907374 0.22 ENST00000550458.1
SRSF9
serine/arginine-rich splicing factor 9
chr17_-_73840415 0.22 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D
unc-13 homolog D (C. elegans)
chr14_+_52313833 0.22 ENST00000553560.1
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr19_-_41220957 0.22 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
ADCK4
aarF domain containing kinase 4
chr16_+_28875268 0.22 ENST00000395532.4
SH2B1
SH2B adaptor protein 1
chr11_-_62474803 0.21 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr19_+_46000479 0.21 ENST00000456399.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr3_+_50316458 0.21 ENST00000316436.3
LSMEM2
leucine-rich single-pass membrane protein 2
chr11_-_64013288 0.21 ENST00000542235.1
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr10_+_104404644 0.21 ENST00000462202.2
TRIM8
tripartite motif containing 8
chr2_-_74710078 0.21 ENST00000290418.4
CCDC142
coiled-coil domain containing 142
chr16_+_29819372 0.21 ENST00000568544.1
ENST00000569978.1
MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_-_27593180 0.21 ENST00000493344.2
ENST00000445933.2
EIF2B4
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr22_-_42310570 0.20 ENST00000457093.1
SHISA8
shisa family member 8
chr10_-_52645416 0.20 ENST00000374001.2
ENST00000373997.3
ENST00000373995.3
ENST00000282641.2
ENST00000395495.1
ENST00000414883.1
A1CF
APOBEC1 complementation factor
chr3_-_167813132 0.20 ENST00000309027.4
GOLIM4
golgi integral membrane protein 4
chr12_+_121416489 0.20 ENST00000541395.1
ENST00000544413.1
HNF1A
HNF1 homeobox A
chr14_+_104182105 0.20 ENST00000311141.2
ZFYVE21
zinc finger, FYVE domain containing 21
chr16_-_30798492 0.20 ENST00000262525.4
ZNF629
zinc finger protein 629
chr12_-_56122220 0.20 ENST00000552692.1
CD63
CD63 molecule
chr19_+_5914213 0.20 ENST00000222125.5
ENST00000452990.2
ENST00000588865.1
CAPS
calcyphosine
chr16_+_67360712 0.20 ENST00000569499.2
ENST00000329956.6
ENST00000561948.1
LRRC36
leucine rich repeat containing 36
chr14_+_32546274 0.20 ENST00000396582.2
ARHGAP5
Rho GTPase activating protein 5
chr22_+_47016277 0.20 ENST00000406902.1
GRAMD4
GRAM domain containing 4
chr1_-_19229014 0.20 ENST00000538839.1
ENST00000290597.5
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr11_+_71164149 0.19 ENST00000319023.2
NADSYN1
NAD synthetase 1
chr3_-_8686479 0.19 ENST00000544814.1
ENST00000427408.1
SSUH2
ssu-2 homolog (C. elegans)
chr12_-_56122124 0.19 ENST00000552754.1
CD63
CD63 molecule
chr12_+_53848549 0.19 ENST00000439930.3
ENST00000548933.1
ENST00000562264.1
PCBP2
poly(rC) binding protein 2
chr15_-_78112553 0.19 ENST00000562933.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr17_+_7211280 0.19 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A
eukaryotic translation initiation factor 5A
chr1_+_206730484 0.19 ENST00000304534.8
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr1_+_28918712 0.18 ENST00000373826.3
RAB42
RAB42, member RAS oncogene family
chr3_-_49722523 0.18 ENST00000448220.1
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_-_33160231 0.18 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2
collagen, type XI, alpha 2
chr3_+_29322803 0.18 ENST00000396583.3
ENST00000383767.2
RBMS3
RNA binding motif, single stranded interacting protein 3
chr14_-_55878538 0.18 ENST00000247178.5
ATG14
autophagy related 14
chr17_-_26989136 0.18 ENST00000247020.4
SDF2
stromal cell-derived factor 2
chr17_-_27418537 0.18 ENST00000408971.2
TIAF1
TGFB1-induced anti-apoptotic factor 1
chr11_-_568369 0.18 ENST00000534540.1
ENST00000528245.1
ENST00000500447.1
ENST00000533920.1
MIR210HG
MIR210 host gene (non-protein coding)
chrX_-_129299847 0.17 ENST00000319908.3
ENST00000287295.3
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr12_+_53848505 0.17 ENST00000552819.1
ENST00000455667.3
PCBP2
poly(rC) binding protein 2
chr12_-_56121580 0.17 ENST00000550776.1
CD63
CD63 molecule
chr12_+_50366620 0.17 ENST00000315520.5
AQP6
aquaporin 6, kidney specific
chr19_+_45174994 0.17 ENST00000403660.3
CEACAM19
carcinoembryonic antigen-related cell adhesion molecule 19
chr22_+_25202232 0.17 ENST00000400358.4
ENST00000400359.4
SGSM1
small G protein signaling modulator 1
chr16_-_103572 0.17 ENST00000293860.5
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr22_-_37640456 0.17 ENST00000405484.1
ENST00000441619.1
ENST00000406508.1
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr22_-_31742218 0.16 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr12_+_7060508 0.16 ENST00000541698.1
ENST00000542462.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_+_77425972 0.16 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr8_-_107782463 0.16 ENST00000311955.3
ABRA
actin-binding Rho activating protein
chr13_-_30160925 0.16 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr12_+_121416340 0.16 ENST00000257555.6
ENST00000400024.2
HNF1A
HNF1 homeobox A
chr1_+_17866290 0.16 ENST00000361221.3
ENST00000452522.1
ENST00000434513.1
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr9_+_131084815 0.16 ENST00000300452.3
ENST00000609948.1
COQ4
coenzyme Q4
chr16_-_790887 0.16 ENST00000540986.1
NARFL
nuclear prelamin A recognition factor-like
chr20_-_52687059 0.16 ENST00000371435.2
ENST00000395961.3
BCAS1
breast carcinoma amplified sequence 1
chr16_+_103816 0.16 ENST00000383018.3
ENST00000417493.1
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr1_-_114447683 0.16 ENST00000256658.4
ENST00000369564.1
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr1_-_155211017 0.16 ENST00000536770.1
ENST00000368373.3
GBA
glucosidase, beta, acid
chr12_+_54379569 0.16 ENST00000513209.1
RP11-834C11.12
RP11-834C11.12
chr2_-_65659762 0.16 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr14_+_104182061 0.16 ENST00000216602.6
ZFYVE21
zinc finger, FYVE domain containing 21
chr1_+_116915270 0.16 ENST00000418797.1
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr8_+_7705398 0.16 ENST00000400125.2
ENST00000434307.2
ENST00000326558.5
ENST00000351436.4
ENST00000528033.1
SPAG11A
sperm associated antigen 11A
chr19_+_49109990 0.16 ENST00000321762.1
SPACA4
sperm acrosome associated 4
chr1_+_55181490 0.15 ENST00000371281.3
TTC4
tetratricopeptide repeat domain 4
chr11_-_2160180 0.15 ENST00000381406.4
IGF2
insulin-like growth factor 2 (somatomedin A)
chr15_-_90039805 0.15 ENST00000544600.1
ENST00000268122.4
RHCG
Rh family, C glycoprotein
chrX_-_129299638 0.15 ENST00000535724.1
ENST00000346424.2
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr20_+_8112824 0.15 ENST00000378641.3
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific)
chr16_-_790982 0.15 ENST00000301694.5
ENST00000251588.2
NARFL
nuclear prelamin A recognition factor-like
chr8_-_7320974 0.15 ENST00000528943.1
ENST00000359758.5
ENST00000361111.2
ENST00000398462.2
ENST00000297498.2
ENST00000317900.5
SPAG11B
sperm associated antigen 11B
chr17_-_79827808 0.15 ENST00000580685.1
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chrX_-_54209640 0.15 ENST00000375180.2
ENST00000328235.4
ENST00000477084.1
FAM120C
family with sequence similarity 120C
chr11_-_61129306 0.15 ENST00000544118.1
CYB561A3
cytochrome b561 family, member A3
chr6_-_31864977 0.15 ENST00000395728.3
ENST00000375528.4
EHMT2
euchromatic histone-lysine N-methyltransferase 2
chr17_-_4889508 0.15 ENST00000574606.2
CAMTA2
calmodulin binding transcription activator 2
chr2_+_105471969 0.15 ENST00000361360.2
POU3F3
POU class 3 homeobox 3
chr10_+_81272287 0.15 ENST00000520547.2
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr8_+_38644715 0.15 ENST00000317827.4
ENST00000379931.3
TACC1
transforming, acidic coiled-coil containing protein 1
chr2_+_27593389 0.15 ENST00000233575.2
ENST00000543024.1
ENST00000537606.1
SNX17
sorting nexin 17
chr19_+_6772710 0.15 ENST00000304076.2
ENST00000602142.1
ENST00000596764.1
VAV1
vav 1 guanine nucleotide exchange factor
chr1_-_153600656 0.15 ENST00000339556.4
ENST00000440685.2
S100A13
S100 calcium binding protein A13
chr6_-_30640761 0.15 ENST00000415603.1
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr2_-_27593306 0.15 ENST00000347454.4
EIF2B4
eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
chr12_-_24737089 0.14 ENST00000483544.1
LINC00477
long intergenic non-protein coding RNA 477
chr6_+_43612750 0.14 ENST00000372165.4
ENST00000372163.4
RSPH9
radial spoke head 9 homolog (Chlamydomonas)
chr8_+_145086574 0.14 ENST00000377470.3
ENST00000447830.2
SPATC1
spermatogenesis and centriole associated 1
chr22_-_24110063 0.14 ENST00000520222.1
ENST00000401675.3
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr15_+_31619013 0.14 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr1_+_27561104 0.14 ENST00000361771.3
WDTC1
WD and tetratricopeptide repeats 1
chr11_-_125365435 0.14 ENST00000524435.1
FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chr1_+_156084461 0.14 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr12_+_118573663 0.14 ENST00000261313.2
PEBP1
phosphatidylethanolamine binding protein 1
chr16_+_3019246 0.14 ENST00000318782.8
ENST00000293978.8
PAQR4
progestin and adipoQ receptor family member IV
chr7_+_140373619 0.14 ENST00000483369.1
ADCK2
aarF domain containing kinase 2
chr8_+_38644778 0.14 ENST00000276520.8
TACC1
transforming, acidic coiled-coil containing protein 1
chr6_+_35995531 0.14 ENST00000229794.4
MAPK14
mitogen-activated protein kinase 14
chr11_-_118966167 0.13 ENST00000530167.1
H2AFX
H2A histone family, member X
chr10_-_52645379 0.13 ENST00000395489.2
A1CF
APOBEC1 complementation factor
chr11_+_61159832 0.13 ENST00000334888.5
ENST00000398979.3
TMEM216
transmembrane protein 216
chr17_+_20059358 0.13 ENST00000536879.1
ENST00000395522.2
ENST00000395525.3
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1
chr16_+_30671223 0.13 ENST00000568722.1
FBRS
fibrosin
chr17_-_73840774 0.13 ENST00000207549.4
UNC13D
unc-13 homolog D (C. elegans)
chr6_-_134638767 0.13 ENST00000524929.1
SGK1
serum/glucocorticoid regulated kinase 1
chr15_-_64673665 0.13 ENST00000300035.4
KIAA0101
KIAA0101
chr10_-_71906342 0.13 ENST00000287078.6
ENST00000335494.5
TYSND1
trypsin domain containing 1
chr1_-_51796226 0.13 ENST00000451380.1
ENST00000371747.3
ENST00000439482.1
TTC39A
tetratricopeptide repeat domain 39A
chr17_+_7155343 0.13 ENST00000573513.1
ENST00000354429.2
ENST00000574255.1
ENST00000396627.2
ENST00000356683.2
ELP5
elongator acetyltransferase complex subunit 5
chr17_+_1633755 0.13 ENST00000545662.1
WDR81
WD repeat domain 81
chr17_-_39156138 0.13 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr12_+_7060432 0.13 ENST00000318974.9
ENST00000456013.1
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr14_+_23564700 0.12 ENST00000554203.1
C14orf119
chromosome 14 open reading frame 119
chrX_-_45060135 0.12 ENST00000398000.2
ENST00000377934.4
CXorf36
chromosome X open reading frame 36
chr11_-_1643368 0.12 ENST00000399682.1
KRTAP5-4
keratin associated protein 5-4
chr19_-_56109119 0.12 ENST00000587678.1
FIZ1
FLT3-interacting zinc finger 1
chr7_-_65447192 0.12 ENST00000421103.1
ENST00000345660.6
ENST00000304895.4
GUSB
glucuronidase, beta
chr3_-_182703688 0.12 ENST00000466812.1
ENST00000487822.1
ENST00000460412.1
ENST00000469954.1
DCUN1D1
DCN1, defective in cullin neddylation 1, domain containing 1
chr5_-_180632147 0.12 ENST00000274773.7
TRIM7
tripartite motif containing 7
chr1_+_26798955 0.12 ENST00000361427.5
HMGN2
high mobility group nucleosomal binding domain 2
chr3_-_133614467 0.12 ENST00000469959.1
RAB6B
RAB6B, member RAS oncogene family
chr4_+_103422499 0.12 ENST00000511926.1
ENST00000507079.1
NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_95972822 0.12 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_32687923 0.12 ENST00000309777.6
ENST00000344461.3
ENST00000373593.1
ENST00000545122.1
TMEM234
transmembrane protein 234
chr1_+_86064794 0.12 ENST00000426794.1
RP11-290M5.2
RP11-290M5.2
chr3_+_184037466 0.12 ENST00000441154.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_+_153600869 0.12 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1

Network of associatons between targets according to the STRING database.

First level regulatory network of KLF12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035623 renal glucose absorption(GO:0035623)
0.1 1.7 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.1 0.4 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.7 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.1 0.4 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.2 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.4 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.1 0.3 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.1 0.3 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.3 GO:1990637 response to prolactin(GO:1990637)
0.1 0.2 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.1 0.3 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.1 0.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.5 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 0.2 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 0.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.1 0.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 0.2 GO:0035696 monocyte extravasation(GO:0035696) regulation of fertilization(GO:0080154) activation of meiosis(GO:0090427) regulation of monocyte extravasation(GO:2000437)
0.0 0.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.4 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:1901804 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.0 0.2 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.3 GO:0070092 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.4 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.1 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.3 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.0 0.2 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.0 0.1 GO:0060061 Spemann organizer formation(GO:0060061)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.3 GO:0031947 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.0 0.1 GO:0072025 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric DCT cell differentiation(GO:0072240)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.2 GO:2000767 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.3 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.2 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:0042144 vacuole fusion, non-autophagic(GO:0042144)
0.0 0.1 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:0072300 positive regulation of metanephric glomerulus development(GO:0072300)
0.0 0.0 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.4 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:0098582 innate vocalization behavior(GO:0098582)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.5 GO:0006882 cellular zinc ion homeostasis(GO:0006882)
0.0 0.1 GO:0046836 glycolipid transport(GO:0046836)
0.0 0.1 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0 0.1 GO:0015824 proline transport(GO:0015824)
0.0 0.1 GO:0061086 regulation of mRNA export from nucleus(GO:0010793) negative regulation of histone H3-K27 methylation(GO:0061086) chromatin maintenance(GO:0070827)
0.0 0.3 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.1 GO:0030047 actin modification(GO:0030047)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.3 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.5 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0097361 CIA complex(GO:0097361)
0.0 0.7 GO:0043203 axon hillock(GO:0043203)
0.0 0.3 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:1990393 3M complex(GO:1990393)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.8 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.8 GO:0000792 heterochromatin(GO:0000792)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.3 GO:0016731 ferredoxin-NADP+ reductase activity(GO:0004324) NADPH-adrenodoxin reductase activity(GO:0015039) oxidoreductase activity, acting on iron-sulfur proteins as donors(GO:0016730) oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor(GO:0016731)
0.1 0.6 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.4 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
0.1 0.2 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity(GO:0003842)
0.1 0.4 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.4 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.1 0.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 1.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.4 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.0 0.5 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.1 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.9 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.2 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.1 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.3 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.0 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.3 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.0 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.0 GO:0071633 dihydroceramidase activity(GO:0071633)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 1.1 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.7 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 1.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+