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A549 cells infected with RSV Analysis Results (GEO series: GSE147507)

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Results for IRF7

Z-value: 1.18

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Transcription factors associated with IRF7

Gene Symbol Gene ID Gene Info
IRF7
ENSG00000185507.15 interferon regulatory factor 7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
IRF7hg19_v2_chr11_-_615942_6159990.109.0e-01Click!

Activity profile of IRF7 motif

Sorted Z-values of IRF7 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_91152303 0.70 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr4_-_169401628 0.65 ENST00000514748.1
ENST00000512371.1
ENST00000260184.7
ENST00000505890.1
ENST00000511577.1
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr12_+_113416265 0.60 ENST00000449768.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr1_-_150693318 0.58 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1
HORMA domain containing 1
chr10_-_9801179 0.55 ENST00000419836.1
RP5-1051H14.2
RP5-1051H14.2
chr3_-_114035026 0.54 ENST00000570269.1
RP11-553L6.5
RP11-553L6.5
chr6_-_85473073 0.49 ENST00000606621.1
TBX18
T-box 18
chr1_-_150693305 0.47 ENST00000368987.1
HORMAD1
HORMA domain containing 1
chr4_-_14889791 0.45 ENST00000509654.1
ENST00000515031.1
ENST00000505089.2
LINC00504
long intergenic non-protein coding RNA 504
chr19_-_39735646 0.44 ENST00000413851.2
IFNL3
interferon, lambda 3
chr2_-_152118276 0.44 ENST00000409092.1
RBM43
RNA binding motif protein 43
chr10_+_91061712 0.42 ENST00000371826.3
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr10_-_5446786 0.42 ENST00000479328.1
ENST00000380419.3
TUBAL3
tubulin, alpha-like 3
chr1_+_155829341 0.41 ENST00000539162.1
SYT11
synaptotagmin XI
chr20_-_32580924 0.39 ENST00000432859.1
RP5-1125A11.1
RP5-1125A11.1
chr5_+_121297650 0.37 ENST00000339397.4
SRFBP1
serum response factor binding protein 1
chr4_-_130014729 0.37 ENST00000281142.5
ENST00000434680.1
SCLT1
sodium channel and clathrin linker 1
chr5_-_133706695 0.37 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr16_-_11350036 0.35 ENST00000332029.2
SOCS1
suppressor of cytokine signaling 1
chr17_-_62499334 0.35 ENST00000579996.1
DDX5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr18_-_21977748 0.35 ENST00000399441.4
ENST00000319481.3
OSBPL1A
oxysterol binding protein-like 1A
chr17_-_57229155 0.35 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr9_+_21409146 0.35 ENST00000380205.1
IFNA8
interferon, alpha 8
chr14_-_55738788 0.35 ENST00000556183.1
RP11-665C16.6
RP11-665C16.6
chr7_-_111424506 0.34 ENST00000450156.1
ENST00000494651.2
DOCK4
dedicator of cytokinesis 4
chrX_-_71525742 0.34 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr7_-_76955563 0.34 ENST00000441833.2
GSAP
gamma-secretase activating protein
chr2_-_118943930 0.32 ENST00000449075.1
ENST00000414886.1
ENST00000449819.1
AC093901.1
AC093901.1
chr2_+_99771418 0.32 ENST00000393473.2
ENST00000393477.3
ENST00000393474.3
ENST00000340066.1
ENST00000393471.2
ENST00000449211.1
ENST00000434566.1
ENST00000410042.1
LIPT1
MRPL30
lipoyltransferase 1
39S ribosomal protein L30, mitochondrial
chr8_+_42873548 0.32 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr2_-_128785619 0.31 ENST00000450957.1
SAP130
Sin3A-associated protein, 130kDa
chr1_-_115301235 0.31 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr11_+_17298543 0.30 ENST00000533926.1
NUCB2
nucleobindin 2
chr15_+_63354769 0.30 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chr1_+_79086088 0.30 ENST00000370751.5
ENST00000342282.3
IFI44L
interferon-induced protein 44-like
chr11_+_17298522 0.30 ENST00000529313.1
NUCB2
nucleobindin 2
chr17_+_15604513 0.30 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr8_+_9009296 0.30 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr7_-_92146729 0.29 ENST00000541751.1
PEX1
peroxisomal biogenesis factor 1
chr6_+_31105426 0.29 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chrX_+_51486481 0.29 ENST00000340438.4
GSPT2
G1 to S phase transition 2
chr21_+_35553045 0.29 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr2_-_55237484 0.29 ENST00000394609.2
RTN4
reticulon 4
chr5_+_131746575 0.29 ENST00000337752.2
ENST00000378947.3
ENST00000407797.1
C5orf56
chromosome 5 open reading frame 56
chr21_+_34144411 0.28 ENST00000382375.4
ENST00000453404.1
ENST00000382378.1
ENST00000477513.1
C21orf49
chromosome 21 open reading frame 49
chr1_+_104068562 0.28 ENST00000423855.2
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr11_+_129936836 0.28 ENST00000597197.1
AP003041.2
Uncharacterized protein
chr5_+_180682720 0.28 ENST00000599439.1
AC008443.1
CDNA: FLJ23158 fis, clone LNG09623; Uncharacterized protein
chr4_-_40517984 0.28 ENST00000381795.6
RBM47
RNA binding motif protein 47
chr10_+_91092241 0.27 ENST00000371811.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr4_-_187112626 0.27 ENST00000596414.1
AC110771.1
Uncharacterized protein
chr1_+_158979680 0.27 ENST00000368131.4
ENST00000340979.6
IFI16
interferon, gamma-inducible protein 16
chr15_+_78832747 0.27 ENST00000560217.1
ENST00000044462.7
ENST00000559082.1
ENST00000559948.1
ENST00000413382.2
ENST00000559146.1
ENST00000558281.1
PSMA4
proteasome (prosome, macropain) subunit, alpha type, 4
chr12_+_19358192 0.27 ENST00000538305.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr10_+_91174486 0.27 ENST00000416601.1
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr2_-_188419078 0.27 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr7_-_111424462 0.27 ENST00000437129.1
DOCK4
dedicator of cytokinesis 4
chr5_+_133707252 0.26 ENST00000506787.1
ENST00000507277.1
UBE2B
ubiquitin-conjugating enzyme E2B
chr12_-_10324716 0.26 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1
oxidized low density lipoprotein (lectin-like) receptor 1
chr3_+_100120441 0.26 ENST00000489752.1
LNP1
leukemia NUP98 fusion partner 1
chrX_+_78003204 0.26 ENST00000435339.3
ENST00000514744.1
LPAR4
lysophosphatidic acid receptor 4
chr11_-_5537920 0.26 ENST00000380184.1
UBQLNL
ubiquilin-like
chr3_+_122283175 0.26 ENST00000383661.3
DTX3L
deltex 3-like (Drosophila)
chr12_+_40618764 0.25 ENST00000343742.2
LRRK2
leucine-rich repeat kinase 2
chr14_+_73563735 0.25 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr4_-_76944621 0.25 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr1_+_158979792 0.25 ENST00000359709.3
ENST00000430894.2
IFI16
interferon, gamma-inducible protein 16
chr1_-_108743471 0.24 ENST00000569674.1
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr14_-_35183755 0.24 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr8_-_30002179 0.24 ENST00000320542.3
MBOAT4
membrane bound O-acyltransferase domain containing 4
chrX_-_20237059 0.24 ENST00000457145.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr12_+_113416191 0.24 ENST00000342315.4
ENST00000392583.2
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chr6_+_87865262 0.24 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr10_+_86184676 0.24 ENST00000543283.1
CCSER2
coiled-coil serine-rich protein 2
chr1_+_104104379 0.24 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr4_-_129207942 0.24 ENST00000503588.1
PGRMC2
progesterone receptor membrane component 2
chr7_-_92777606 0.24 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr11_+_3875757 0.24 ENST00000525403.1
STIM1
stromal interaction molecule 1
chr10_+_114710516 0.24 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr1_+_158979686 0.24 ENST00000368132.3
ENST00000295809.7
IFI16
interferon, gamma-inducible protein 16
chr9_+_4985016 0.23 ENST00000539801.1
JAK2
Janus kinase 2
chr3_-_28390581 0.23 ENST00000479665.1
AZI2
5-azacytidine induced 2
chr15_-_80263506 0.23 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr10_+_91087651 0.23 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_+_153191706 0.23 ENST00000288670.9
FMNL2
formin-like 2
chr6_+_142468383 0.23 ENST00000367621.1
ENST00000452973.2
VTA1
vesicle (multivesicular body) trafficking 1
chr5_+_68788594 0.23 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr9_-_119162885 0.23 ENST00000445861.2
PAPPA-AS1
PAPPA antisense RNA 1
chr11_-_119249805 0.22 ENST00000527843.1
USP2
ubiquitin specific peptidase 2
chr19_+_49977466 0.22 ENST00000596435.1
ENST00000344019.3
ENST00000597551.1
ENST00000204637.2
ENST00000600429.1
FLT3LG
fms-related tyrosine kinase 3 ligand
chr3_-_187455680 0.22 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr11_+_9406169 0.22 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr21_+_18811205 0.22 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr1_+_59486129 0.22 ENST00000438195.1
ENST00000424308.1
RP4-794H19.4
RP4-794H19.4
chr18_+_61575200 0.22 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr3_+_185046676 0.22 ENST00000428617.1
ENST00000443863.1
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr11_-_60720002 0.22 ENST00000538739.1
SLC15A3
solute carrier family 15 (oligopeptide transporter), member 3
chr12_+_19358228 0.21 ENST00000424268.1
ENST00000543806.1
PLEKHA5
pleckstrin homology domain containing, family A member 5
chr1_+_104068312 0.21 ENST00000524631.1
ENST00000531883.1
ENST00000533099.1
ENST00000527062.1
RNPC3
RNA-binding region (RNP1, RRM) containing 3
chr12_+_113416340 0.21 ENST00000552756.1
OAS2
2'-5'-oligoadenylate synthetase 2, 69/71kDa
chrX_-_71526999 0.21 ENST00000453707.2
ENST00000373619.3
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr11_-_47736896 0.21 ENST00000525123.1
ENST00000528244.1
ENST00000532595.1
ENST00000529154.1
ENST00000530969.1
AGBL2
ATP/GTP binding protein-like 2
chr6_+_134273300 0.21 ENST00000416965.1
TBPL1
TBP-like 1
chr6_-_35888905 0.21 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRPK1
SRSF protein kinase 1
chr14_+_32546145 0.20 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr8_+_72755367 0.20 ENST00000537896.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr5_+_38845960 0.20 ENST00000502536.1
OSMR
oncostatin M receptor
chr15_+_96875657 0.20 ENST00000559679.1
ENST00000394171.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_-_38978847 0.20 ENST00000269576.5
KRT10
keratin 10
chr2_+_172950227 0.20 ENST00000341900.6
DLX1
distal-less homeobox 1
chr1_+_159796534 0.20 ENST00000289707.5
SLAMF8
SLAM family member 8
chr17_+_6659153 0.20 ENST00000441631.1
ENST00000438512.1
ENST00000346752.4
ENST00000361842.3
XAF1
XIAP associated factor 1
chr1_+_186265399 0.20 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
PRG4
proteoglycan 4
chr13_+_20532848 0.20 ENST00000382874.2
ZMYM2
zinc finger, MYM-type 2
chr6_+_122931366 0.20 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr9_+_67977438 0.20 ENST00000456982.1
RP11-195B21.3
Protein LOC644249
chr2_-_191878874 0.20 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_37384175 0.20 ENST00000411537.2
ENST00000233057.4
ENST00000395127.2
ENST00000390013.3
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr18_+_52258390 0.20 ENST00000321600.1
DYNAP
dynactin associated protein
chr4_-_39034542 0.19 ENST00000344606.6
TMEM156
transmembrane protein 156
chr10_-_92681033 0.19 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_+_150245177 0.19 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr17_-_40264321 0.19 ENST00000430773.1
ENST00000413196.2
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr19_-_58485895 0.19 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr14_-_54908043 0.19 ENST00000556113.1
ENST00000553660.1
ENST00000395573.4
ENST00000557690.1
ENST00000216416.4
CNIH1
cornichon family AMPA receptor auxiliary protein 1
chr22_-_22641542 0.19 ENST00000606654.1
LL22NC03-2H8.5
LL22NC03-2H8.5
chr6_+_116575329 0.19 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
DSE
RP3-486I3.7
dermatan sulfate epimerase
RP3-486I3.7
chr7_+_142498725 0.19 ENST00000466254.1
TRBC2
T cell receptor beta constant 2
chr14_-_69263043 0.19 ENST00000408913.2
ZFP36L1
ZFP36 ring finger protein-like 1
chr15_+_42565844 0.19 ENST00000566442.1
GANC
glucosidase, alpha; neutral C
chr7_-_83824449 0.18 ENST00000420047.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr4_-_129208030 0.18 ENST00000503872.1
PGRMC2
progesterone receptor membrane component 2
chr15_-_77712429 0.18 ENST00000564328.1
ENST00000558305.1
PEAK1
pseudopodium-enriched atypical kinase 1
chr2_-_191878681 0.18 ENST00000409465.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr4_-_169239921 0.18 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr9_-_32526184 0.18 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr3_+_97483572 0.18 ENST00000335979.2
ENST00000394206.1
ARL6
ADP-ribosylation factor-like 6
chr8_-_79717750 0.18 ENST00000263851.4
ENST00000379113.2
IL7
interleukin 7
chr8_+_27632083 0.18 ENST00000519637.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr11_+_93861993 0.18 ENST00000227638.3
ENST00000436171.2
PANX1
pannexin 1
chr10_+_22610876 0.18 ENST00000442508.1
BMI1
BMI1 polycomb ring finger oncogene
chr1_-_114430169 0.18 ENST00000393316.3
BCL2L15
BCL2-like 15
chr4_+_187112674 0.17 ENST00000378802.4
CYP4V2
cytochrome P450, family 4, subfamily V, polypeptide 2
chr1_-_207119738 0.17 ENST00000356495.4
PIGR
polymeric immunoglobulin receptor
chr7_+_112063192 0.17 ENST00000005558.4
IFRD1
interferon-related developmental regulator 1
chr20_-_56195449 0.17 ENST00000541799.1
ZBP1
Z-DNA binding protein 1
chr1_-_89488510 0.17 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr5_-_146461027 0.17 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr12_+_72058130 0.17 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr18_-_72264805 0.17 ENST00000577806.1
LINC00909
long intergenic non-protein coding RNA 909
chr5_-_78281623 0.17 ENST00000521117.1
ARSB
arylsulfatase B
chr3_-_28389922 0.17 ENST00000415852.1
AZI2
5-azacytidine induced 2
chr9_-_20622478 0.17 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr8_-_101733794 0.17 ENST00000523555.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr5_+_40841410 0.17 ENST00000381677.3
CARD6
caspase recruitment domain family, member 6
chr11_-_18258342 0.16 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr5_+_133706865 0.16 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chr5_+_38846101 0.16 ENST00000274276.3
OSMR
oncostatin M receptor
chr17_-_40264692 0.16 ENST00000591220.1
ENST00000251642.3
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr1_-_111506562 0.16 ENST00000485275.2
ENST00000369763.4
LRIF1
ligand dependent nuclear receptor interacting factor 1
chr10_+_24498060 0.16 ENST00000376454.3
ENST00000376452.3
KIAA1217
KIAA1217
chr6_+_147527103 0.16 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr17_-_39156138 0.16 ENST00000391587.1
KRTAP3-2
keratin associated protein 3-2
chr9_-_123812542 0.16 ENST00000223642.1
C5
complement component 5
chr2_-_231084659 0.16 ENST00000258381.6
ENST00000358662.4
ENST00000455674.1
ENST00000392048.3
SP110
SP110 nuclear body protein
chr6_+_26440700 0.16 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
BTN3A3
butyrophilin, subfamily 3, member A3
chr12_-_31479045 0.16 ENST00000539409.1
ENST00000395766.1
FAM60A
family with sequence similarity 60, member A
chr13_-_86373536 0.16 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr17_-_65362678 0.16 ENST00000357146.4
ENST00000356126.3
PSMD12
proteasome (prosome, macropain) 26S subunit, non-ATPase, 12
chr14_+_90864504 0.16 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chrX_+_146993534 0.16 ENST00000334557.6
ENST00000439526.2
ENST00000370475.4
FMR1
fragile X mental retardation 1
chr12_-_72057571 0.15 ENST00000548100.1
ZFC3H1
zinc finger, C3H1-type containing
chr5_-_58571935 0.15 ENST00000503258.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr17_+_6659354 0.15 ENST00000574907.1
XAF1
XIAP associated factor 1
chr17_-_33905521 0.15 ENST00000225873.4
PEX12
peroxisomal biogenesis factor 12
chr11_-_47869865 0.15 ENST00000530326.1
ENST00000532747.1
NUP160
nucleoporin 160kDa
chr3_+_122399444 0.15 ENST00000474629.2
PARP14
poly (ADP-ribose) polymerase family, member 14
chrX_+_49969405 0.15 ENST00000376042.1
CCNB3
cyclin B3
chr5_+_82373317 0.15 ENST00000282268.3
ENST00000338635.6
XRCC4
X-ray repair complementing defective repair in Chinese hamster cells 4
chr6_+_160693591 0.15 ENST00000419196.1
RP1-276N6.2
RP1-276N6.2
chr2_-_190044480 0.15 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr4_-_103746924 0.15 ENST00000505207.1
ENST00000502404.1
ENST00000507845.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr6_-_99873145 0.15 ENST00000369239.5
ENST00000438806.1
PNISR
PNN-interacting serine/arginine-rich protein
chr5_-_98262240 0.15 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr4_-_185395191 0.15 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr17_-_74489215 0.15 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr1_+_43613612 0.15 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr10_+_91174314 0.15 ENST00000371795.4
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chr9_+_6215799 0.15 ENST00000417746.2
ENST00000456383.2
IL33
interleukin 33
chr1_-_149783914 0.15 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
HIST2H2BF
histone cluster 2, H2bf
chr12_+_102271436 0.15 ENST00000544152.1
DRAM1
DNA-damage regulated autophagy modulator 1
chr14_-_69262916 0.15 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr12_+_113376157 0.14 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr19_+_17516624 0.14 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
CTD-2521M24.9
CTD-2521M24.9
chr18_-_29264467 0.14 ENST00000383131.3
ENST00000237019.7
B4GALT6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr2_-_55277692 0.14 ENST00000394611.2
RTN4
reticulon 4
chr5_+_34915444 0.14 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr4_+_186990298 0.14 ENST00000296795.3
ENST00000513189.1
TLR3
toll-like receptor 3
chr10_+_51549498 0.14 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr12_+_79258547 0.14 ENST00000457153.2
SYT1
synaptotagmin I

Network of associatons between targets according to the STRING database.

First level regulatory network of IRF7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0060629 meiotic DNA double-strand break formation(GO:0042138) regulation of homologous chromosome segregation(GO:0060629)
0.2 0.7 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.6 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.5 GO:1905154 negative regulation of membrane invagination(GO:1905154) calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.4 GO:0060829 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827) negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 0.5 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.4 GO:0010520 regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903)
0.1 0.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 1.0 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.7 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.5 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.3 GO:1903217 negative regulation of late endosome to lysosome transport(GO:1902823) regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.1 0.4 GO:1901545 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.6 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.3 GO:0060151 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)
0.1 0.2 GO:0061580 colon epithelial cell migration(GO:0061580)
0.1 0.2 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.1 0.9 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.6 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.2 GO:0010983 positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.1 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.4 GO:0048625 myoblast fate commitment(GO:0048625)
0.1 0.4 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.1 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:0061074 regulation of neural retina development(GO:0061074)
0.0 0.2 GO:1902724 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.4 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.0 0.2 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.3 GO:1902031 regulation of NADP metabolic process(GO:1902031)
0.0 0.2 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:0046103 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.1 GO:1904237 regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904235) positive regulation of substrate-dependent cell migration, cell attachment to substrate(GO:1904237)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.3 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.0 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.0 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0090293 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.0 0.0 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0007493 endodermal cell fate determination(GO:0007493)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0006953 acute-phase response(GO:0006953)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.1 GO:0021546 rhombomere development(GO:0021546)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0052056 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.0 0.0 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.2 GO:0000023 maltose metabolic process(GO:0000023)
0.0 0.1 GO:1905123 regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.1 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.0 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.4 GO:0035456 response to interferon-beta(GO:0035456)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.0 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.0 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.0 0.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.3 GO:0007379 segment specification(GO:0007379)
0.0 0.0 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.2 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.0 0.0 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 1.1 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.2 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.0 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.2 GO:0070673 response to interleukin-18(GO:0070673)
0.0 0.0 GO:0071283 cellular response to iron(III) ion(GO:0071283)
0.0 0.1 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.0 GO:0099640 axo-dendritic protein transport(GO:0099640)
0.0 0.1 GO:0045333 cellular respiration(GO:0045333)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0044753 amphisome(GO:0044753)
0.1 0.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 0.2 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.5 GO:0032059 bleb(GO:0032059)
0.0 0.2 GO:0097179 protease inhibitor complex(GO:0097179)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 1.0 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.3 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0097422 tubular endosome(GO:0097422)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.0 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.4 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.1 GO:0036019 endolysosome(GO:0036019)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.0 GO:0031213 RSF complex(GO:0031213)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030626 U12 snRNA binding(GO:0030626)
0.1 0.4 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.1 0.3 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.1 1.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.4 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.2 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.1 0.8 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.3 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.2 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.2 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.1 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0001602 peptide YY receptor activity(GO:0001601) pancreatic polypeptide receptor activity(GO:0001602)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.1 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-4 receptor activity(GO:0004913) interleukin-7 receptor activity(GO:0004917) interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0070336 flap-structured DNA binding(GO:0070336)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.3 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.1 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0004597 peptide-aspartate beta-dioxygenase activity(GO:0004597)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.2 GO:0032450 alpha-1,4-glucosidase activity(GO:0004558) maltose alpha-glucosidase activity(GO:0032450)
0.0 0.1 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.0 GO:0061598 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.0 GO:0008426 protein kinase C inhibitor activity(GO:0008426)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 2.8 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome